The BIOPOOL project aggregates data from European biobanks to facilitate faster and more accurate cancer diagnoses. This initiative enables clinicians to compare biopsy images of patients with those of numerous other patients, reducing the need for invasive tests and improving treatment outcomes.
Påebo is being honored with the prestigious award for his groundbreaking work on extracting DNA from ancient human remains and sequencing Neandertal's nuclear DNA. The prize recognizes his discovery that Neandertals contributed up to 4% of modern humans' genetic material.
Researchers at the University of Manchester have identified a molecular basis for tissue-specific immune regulation in eye and kidney diseases. A common genetic alteration in complement factor H (CFH) is associated with AMD, while a different mutation is linked to rare kidney disease aHUS.
A natural product called genistein-combined polysaccharide (GCP) may help patients with metastatic prostate cancer live longer by blocking a key mechanism used by prostate cancer cells to survive. GCP is expected to be effective in treating patients with low response to androgen-deprivation therapy.
A new study by researchers at the University of Pennsylvania School of Medicine found that minimally invasive therapies can effectively remove damaged cells from patients with Barrett's esophagus, reducing cancer progression. In over two-thirds of cases, patients had no signs of disease return for years.
Researchers discovered a novel use of a fish oil component that reduced brain trauma in newborn mice by about 50%. The study found that injecting docosahexaenoic acid (DHA) within two hours of ischemic stroke significantly decreased neonatal brain damage. DHA provided protection while other omega-3 fatty acids did not.
Employees enrolled in a six-month worksite-based weight loss intervention with behavioral counseling lost an average of 18 pounds, while those in a control group gained two pounds. The study also found improvements in markers for cardiovascular disease and diabetes risk.
Scientists have developed a self-healing protective coating for concrete cracks that can repair itself using sunlight. The coating contains microcapsules loaded with a material that seals cracks upon cracking, providing an environmentally friendly solution to protect infrastructure from deterioration.
A team of UCSF researchers has uncovered the neurological basis of speech motor control, revealing a hierarchical and cyclical structure that exerts split-second control over articulators in fluent speech. The study has potential implications for developing computer-brain interfaces and treating speech disorders.
A new study published in JAMA Dermatology has found that the common acne drug isotretinoin does not increase the risk of inflammatory bowel disease. The research, led by Dr. Mahyar Etminan, statistically adjusted for severe acne and found no association between the drug and IBD.
A new device encircles the esophagus valve to control chronic acid reflux, easing symptoms in 92% of patients and allowing 87% to stop using acid-suppressing drugs. Installation is minimally invasive, taking one to two hours, and patients experience significant improvement with 94% satisfaction.
On July 19, 2012, NASA's Solar Dynamics Observatory (SDO) detected a rare event: coronal rain. This phenomenon occurs when hot plasma in the sun's corona cools and condenses along strong magnetic fields. The SDO's footage shows the plasma as it slowly falls back to the solar surface, outlining the magnetic fields.
A recent study at Washington State University found that viewers of primetime crime dramas are more inclined to intervene on behalf of sexual assault victims. The research suggests that prime-time television can be an effective medium for educating the public about sexual assault and encouraging bystander intervention.
Researchers at Harvard Medical School have identified a signaling pathway that may determine genetic susceptibility for the development of FASD. The study found that phosphorylation events inside cells can render L1 adhesion molecules more vulnerable to alcohol's inhibitory effects, providing new targets for diagnosis and therapy.
A digital processing system has been found to significantly reduce medication errors in US hospitals, with a potential to avoid over 50 million incidents nationwide. The system halves the likelihood of a drug error and cuts errors by 12.5% nationally, resulting in 17.4 million avoided errors in one year.
A study by Duke University Medical Center found that bullied children are at higher risk for psychiatric disorders, including anxiety and depressive disorders, as adults. The research used a large group of participants initially enrolled as adolescents and followed them into adulthood to assess the long-term effects of bullying.
A study published by Henry Ford Hospital found that resveratrol can reduce noise-induced hearing loss and cognitive decline in rats. The researchers discovered that resveratrol inhibits the inflammatory process and oxidative stress caused by loud noise, providing protection against age-related hearing and cognitive impairment.
A new open-source tool, Pipeline, helps leaders manage complex collaborative projects by redistributing leadership responsibilities and tasks. It enables leaders to trust certain individuals with more authority while maintaining accountability.
Research reveals that people with disabilities are three times more likely to experience physical or sexual violence than those without disabilities. Additionally, victims with disability are twice as likely to experience emotional difficulties following violence, highlighting the need for targeted support and prevention programs.
New research shows that criticism from team members can lead to downward spirals, but external criticism can boost performance by encouraging a 'them and us' mentality. This study offers a method for improving performance following setbacks in both sport and business.
Researchers have catalogued the structural diversity of metallic nanoclusters into families using a new numerical simulation method. This breakthrough enables tailoring of specific properties and has potential applications in nanocatalysis and magnetic storage.
Researchers have discovered that ancient Egyptian blue pigment can break apart into nanosheets, producing invisible infrared radiation. These nanosheets have potential applications in near-IR-based biomedical imaging, IR light-emitting devices, and security ink formulations.
Researchers have identified 138 new species of beetles within the Operclipygus genus, significantly expanding our understanding of tropical insect diversity. The study, published in ZooKeys, reveals that these tiny beetles play a crucial role in controlling pest populations and highlights the need for continued conservation efforts.
Research finds no significant linear trend pointing to a decline in UK new drug introductions between 1982-2011, contrary to widely-held views. The number of new drugs introduced has fluctuated, with dips followed by surges, indicating an overall slight increase over the past 40 years.
Researchers at Weill Cornell Medical College and Cornell University have developed bioengineered ears that can grow cartilage over a three-month period. The study's breakthrough could provide a new solution for children born with congenital ear deformities, as well as individuals who have lost part or all of their external ear.
A new study by Imperial College London found that hospital staff satisfaction is closely tied to the quality of patient care. The research suggests that hospitals with lower mortality rates tend to have more satisfied staff, and that non-clinical staff are just as likely to be satisfied as clinical staff.
A new Regenstrief study found that half of infection preventionists are unaware of health information exchange participation, while only 10% are engaged. The researchers also discovered that most preventers lack access to designed tools for sifting through electronic medical record data.
Astronomers used Kepler spacecraft data to discover a planet smaller than Mercury, about the size of Earth's moon, in the Cygnus-Lyra region of the Milky Way. The planet, Kepler-37b, is likely a rocky world with no atmosphere or water.
Bioengineered ears created by Cornell researchers use 3D printing and injectable gels made of living cells to resemble natural ears. The flexible ears can grow cartilage over a three-month period, providing a potential solution for reconstructive surgeons.
A new study suggests that scopolamine can help boost the effectiveness of exposure therapy for anxiety disorders by disrupting contextual processing. Researchers found that administering scopolamine to rats during anxiety-extinction led to fear-recovery being thwarted, suggesting a potential breakthrough in preventing relapse.
A new study published in Environmental Science & Technology found that approximately 60% of the world's population lacks access to improved sanitation. This deficiency is attributed to inadequate sewage treatment and can lead to disease, highlighting the need for better global health standards.
A recent study by Professor Hermann Brenner and colleagues found that smoking cessation in older adults significantly reduces the risk of heart attacks and strokes. Within five years of quitting, smokers experience a reduction of over 40% in cardiovascular disease risk compared to non-smokers.
A new Northwestern University study found that US veterans diagnosed with GERD are frequently prescribed high doses of proton pump inhibitors (PPIs) and kept on the drug for too long. The researchers evaluated over 1,600 patients and found that nearly 25% were given high total daily dose prescriptions.
New research finds that standard bacterial culture tests may overlook certain germs, highlighting the need for multiple detection methods. The study analyzed 44 premature babies and detected over 20 uncultured bacterial species using DNA genomic analysis.
Scientists have identified a challenging parasite that impacts algae biofuel production, highlighting the need for innovative management strategies. The study provides a comprehensive understanding of the parasite's morphology, ultrastructure, and life history, laying the groundwork for sustainable solutions.
A preclinical study uses ultrasonic molecular imaging and Dynamic Contrast Enhanced-Perfusion Imaging to measure response to pancreatic cancer therapy. The study reveals that these new technologies can detect molecular signs of tumor response after just 2 days, improving the early identification of therapeutic response.
A study published in Journal of Eating Disorders found that women's conversations about weight, known as 'fat talk,' were more prevalent during younger years. In contrast, discussions about aging, or 'old talk,' increased with age and were less frequent. Women who engaged in both types of talk tended to have a more negative body image.
A recent genome-wide imaging study has discovered a new gene, BCHE, associated with Alzheimer's plaques. The study found that variants of the BCHE gene are significantly linked to increased levels of amyloid plaque deposits in the brains of patients and those at risk for the disease.
A University of Missouri researcher found that receiving pensions improves health perceptions in older men and women, with women reporting better well-being initially. However, after five years, men's well-being improved before declining, while women's benefits persisted.
Ron Davis, chair of the Neuroscience Department at Scripps Research Institute, has been selected for a prestigious Javits Neuroscience Investigator Award to study active forgetting in memory formation. The grant will focus on understanding the role of dopamine signaling in learning and memory, with potential implications for treating d...
Tomatoes grown on organic farms have higher levels of sugars, vitamin C and antioxidants compared to conventional farming methods. This increase in bioactive compounds is linked to the stressful growth conditions experienced by organic tomatoes.
Decision makers who feel powerful are more likely to make decisions that benefit their future selves. Researchers found that power can embolden decision makers and lead to better long-term choices. Power appears to foster saving behavior by putting people in touch with their future selves.
A new study reveals that slow-firing neurons are essential for higher-order thinking and mental representations, which are compromised in diseases like schizophrenia and Alzheimer's. The research identifies NMDA-NR2B receptors as key regulators of neuronal firing.
The National Institutes of Health is launching a $700 million project to develop a common data-sharing framework for biomedical research. This framework aims to integrate millions of gigabytes of data from various disciplines, enabling researchers to tap into a gold mine of information and improve disease treatment and cure rates.
Researchers are conducting an early-stage human clinical trial of two related candidate vaccines to prevent infection with Shigella bacteria, which causes diarrheal illness particularly among children. The Phase I trial aims to evaluate the vaccines for safety and immune response induction in healthy adults.
Researchers found that fragile X syndrome alters signaling in brain cells, leading to prolonged electrical surges and potential attention problems. Restoring the gene FMRP restored normal signaling.
Researchers found that children with brain lesions use gestures similar to typically developing children to convey simple sentences. They also discovered that producing complex sentences across gesture and speech is delayed in children with larger brain lesions.
Scientists at Georgia Institute of Technology explore an alternate theory for RNA origin, finding molecules that spontaneously assemble into gene-length linear stacks in water. The discovery suggests proto-RNA bases could have formed the first genetic material.
Researchers have developed an injectable hydrogel that can repair damaged cardiac tissue and promote new cell growth after a heart attack. The gel forms a scaffold, encouraging the heart to rebuild itself without triggering adverse immune responses.
A team of doctors and nurses at Johns Hopkins Hospital implemented interventions to improve patient sleep quality, reducing delirium by 54% in ICU patients. The study suggests that simple measures can have a significant impact on patient outcomes and recovery from intensive care.
Scientists at Pacific Northwest National Laboratory have developed a rapid and accurate vapor detection method that identifies minute traces of explosives on luggage, cargo or travelers. The system, which 'sniffs' for explosive vapors, has been demonstrated to detect low-volatility compounds like RDX at levels below parts-per-trillion.
Researchers explore nano-channels to selectively unknnot DNA, with potential applications in sequencing and understanding cell metabolism. The study reveals varying channel widths can drastically change DNA knot complexity.
New findings from a 10-year project led by Professor Derek Abbott reveal that the US Federalist Papers are written by Alexander Hamilton, James Madison, and John Jay with some collaboration. The Letter to the Hebrews is attributed to Saint Paul but shares similarities with other authors like Luke and Barnabas.
A giant sunspot formed on the sun's surface over Feb. 19-20, 2013, with rapid growth to six Earth diameters across in under 48 hours. The spot's delta region exhibited unstable magnetic fields, potentially leading to solar flares.
Cyclone Haruna strengthened into a cyclone with a wide-eyed eye visible on NASA's Aqua satellite. Heavy rainfall was detected by TRMM satellite, with cloud top temperatures colder than -63F (-52C). The storm is expected to make a brief landfall near Androka in Madagascar as it moves southeast into the southern Indian Ocean.
Researchers discovered that ancient sea anemones use the same genes to form their heads as humans and other animals, providing insight into brain evolution. The study found that these 'head genes' control development of sensory centers in both sea anemones and higher animals.
Researchers have discovered how methylene blue modifies tau proteins, which aggregate in Alzheimer's disease. The study reveals that methylene blue deactivates molecular residues promoting bonding and acts as a spacer to keep proteins apart, leading to potential treatment strategies.
Researchers used the Chemical Dynamics Beamline at Berkeley Lab to examine how photochemistry determines isotope ratios in the solar system. They found that mass-independent processes, such as chemical reactions, could explain differences between Earth and meteorites/solar system elements.
A study published in Journal of the Academy of Nutrition and Dietetics found a significant association between high glycemic index diets and dairy consumption with acne. Medical nutrition therapy is recommended as an adjunct treatment for acne treatment. The study suggests that diet may influence or aggravate acne, rather than causing it.
A study on oceanic whitetip sharks reveals they spend most of their time in Bahamian waters but roam long distances, highlighting the need for international conservation measures. The research provides key findings for protecting this species, which is listed as Critically Endangered globally.