Scientists develop the first maturation-based disease model for arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) using patient skin cells. The model mimics adult-onset disease by inducing adult-like metabolism, revealing metabolic malfunction and abnormal protein activation as key drivers of the disease.
A new study reveals that human activities in cities alter atmospheric circulation patterns, leading to significant warming in northern Asia and North America. The study found that the 'waste heat' generated by urban areas can widen the jet stream and increase temperatures across large distances.
Researchers have uncovered the elastic properties of spider silk, with variations among fibers, junctions, and glue spots. The findings provide a blueprint for structural engineering of strong, stretchy, and elastic materials.
Research at Ultra Short Pulse High Intensity Lab in TIFR has found a novel scheme to accelerate neutral particles over millimeters using lasers. The concept uses powerful lasers to strip electrons from argon atoms, accelerating charged ions to high energies.
A study published in BioMed Central's Stem Cell Research & Therapy journal found that stem cells from bone marrow or fat improved brain and nerve repair after stroke in rats. The treated animals showed significant functional recovery, even without the stem cells migrating to the damaged area.
A recent study by Cold Spring Harbor Laboratory researchers has identified a specific class of neurons in the central amygdala as crucial for encoding and recalling fear memories. The team used optogenetics to activate these neurons, which release neurotransmitters that enhance or inhibit synaptic connections, leading to fear responses.
Researchers used dispensary records to measure the effect of forest fires on people with chronic lung diseases. The study found that even small increases in smoke were associated with higher salbutamol dispensations, highlighting the impact of pollution on public health.
Scientists at the University of California, Berkeley, have found a link between poor sleep, memory loss and brain deterioration in older adults. Boosting 'slow wave' sleep may help restore memory, suggesting a potentially new treatment avenue for age-related memory loss.
Researchers at A*STAR's Genome Institute of Singapore discovered four processes that cause mutations in gastric cancer, including one triggered by bacterial infection. These findings pave the way for diagnostics and targeted therapy, with potential implications for improving treatment outcomes.
GATA3 acts downstream to activate microRNA29b, which stops tumor cells from spreading by inhibiting genes involved in metastasis. The absence of GATA3 allows cancerous cells to break free and induce inflammation and new blood vessel formation.
Rice University scientists develop a technique to combine single-atom-thick graphene and hexagonal boron nitride into sheets with controlled patterns. The new method enables the creation of fully functional devices with circuits on the same scale as current semiconductor fabrication.
Researchers find that hot electrons generated by laser pulses cause ultrafast demagnetization in nickel, not the light itself. The study suggests a new possibility for spintronics research.