A University at Buffalo study suggests that high-carbohydrate diets in infancy may lead to increased weight gain and obesity in later life. Researchers found that even moderate caloric restriction could not reverse the programming effect.
A new study from Brigham and Women's Hospital found that physical therapy improves functional status, pain, and physical function in patients with meniscal tears and osteoarthritis. For a third of patients assigned to physical therapy, surgery was still necessary.
A study found that genetic testing can help identify BPH patients at higher risk of developing prostate cancer. Ten single nucleotide polymorphisms were linked to PCa risk, with one marker showing a strong association.
The new HPC data center at NREL's Energy Systems Integration Facility (ESIF) is the first of its kind, boasting an annualized average power usage effectiveness (PUE) rating of 1.06 or better. It achieves this by using warm-water liquid cooling and capturing and reusing waste heat to reduce energy consumption.
A new study from St. Jude Children's Research Hospital found that inherited genetic variations in four genes increase the risk of acute lymphoblastic leukemia in children. The research also showed ethnic differences in the cancer's incidence, with higher rates among Hispanic and African American patients.
Researchers genetically engineered tomatoes to produce a peptide that mimics the action of good cholesterol, reducing inflammation and plaque build-up in mice. The study suggests that targeting the small intestine may be a new strategy to prevent diet-induced atherosclerosis.
A study found that only 6.3% of emergency department visits with primary care-treatable diagnoses also had nonemergency complaints, highlighting the flaws in using discharge diagnosis to predict ED use. Patients with nonemergency-complaint ED visits often required immediate emergency care or hospital admission.
Scientists have cracked the genetic code of bacteria linked to periodontitis, a disease marked by inflammation and infection of the teeth's supporting ligaments and bones. The unique genetic code allows SR1 bacteria to introduce a glycine amino acid, limiting gene exchange with other bacteria.
Scientists warn millions in Asia may be at risk of kidney failure and bladder cancer from taking widely available herbal medicines. A new study proposes protocols for diagnosis and treatment, and suggests a need for better regulation to prevent exposure.
Assistant Professor Hyeok Choi's research aims to develop a sensor system that can detect biological toxins wirelessly, providing real-time data for early warning systems. The system will be deployed in areas with high concentrations of harmful algal blooms, enabling water providers to take action.
A new study challenges the long-held explanation that depression is caused by insufficient serotonin levels. Instead, researchers found that abnormal communication between brain cells is the root cause of depression. This discovery opens possibilities for new therapies targeting excitatory connections rather than serotonin.
A community-based diabetes prevention program, led by health workers, successfully reduced blood glucose levels and improved insulin sensitivity in overweight participants with prediabetes. The study replicated the results of the Diabetes Prevention Project, demonstrating a significant reduction in diabetes risk.
A large-scale study found that oral estrogen therapy increases the risk of gallbladder surgery in postmenopausal women. Women using transdermal therapies like patches or gels were not at increased risk.
Researchers explore naturally occurring egg-hatching factors to control G. pallida, a non-native species causing economic hardship in US potato fields. Using these chemicals to stimulate eggs to hatch when no potato plants are present could be an effective defense against the pest.
A recent study published in JAMA Neurology found that unmedicated adults with hypertension and a genetic risk factor for Alzheimer's disease have higher amyloid plaque levels than other groups. Controlling hypertension may significantly decrease the risk of developing amyloid deposits, even in those with genetic risk.
Researchers developed biodegradable nanoparticles that deliver inflammation-resolving drugs to sites of tissue injury, promoting clearance of pathogens or damaged tissue and restoring normal state. The treatment has potential for treating conditions like atherosclerosis and neurodegenerative diseases.
Research suggests that skimmed/semi-skimmed milk consumption is associated with a higher risk of overweight and obesity in preschool-age children. Milk fat may increase feelings of fullness, reducing appetite for other calorie-dense foods.
Researchers monitored sleeping adolescents' brain waves, finding that synaptic density in the cerebral cortex peaks at age 8 and declines until adulthood. EEG sleep analysis identifies crucial aspects of adolescent brain maturation.
Researchers found a new class of dust motion on the moon, where charged particles swarm like bees around partially shaded regions. This phenomenon creates oscillations over 1-10 meter-sized shaded regions, with dust bouncing back and forth between sunlit areas.
PhenoDB is a new online database that enables clinicians to document cases of unusual genetic diseases, which can then be analyzed by researchers. The database captures standardized information about a person's phenotype, including symptoms and family history, to help understand the genetic variations involved.
A recent study found that preterm infants with low-grade brain bleeding have similar neurodevelopmental outcomes as those with no bleeding. The study analyzed 1472 extremely preterm infants and found that those with grade 1 or 2 PIVH did not have an increased incidence of poor outcomes compared to infants without PIVH.
A new study reveals that male lions use dense savanna vegetation to hunt prey successfully, often ambushing them from behind vegetation. The findings suggest that changes to vegetation structure could impact the balance of predators and prey.
A recent study by Mayo Clinic found that over 2 in 5 parents are hesitant to vaccinate their teenage daughters against human papillomavirus (HPV) due to potential side effects. The vaccine is recommended for teens to prevent cervical cancer and genital cancers, with the majority of experts agreeing on its necessity.
Researchers have found that cuprate superconductors, known for carrying electrical current without resistance, cannot be fully explained by the traditional concept of Luttinger's theorem, which states that electrons carry current. This discovery reveals that there must be alternative explanations beyond electron behavior.
Researchers found a link between lifestyle factors and an increased risk of developing rheumatoid arthritis, with smoking, obesity, and diabetes being key contributors. The study also identified reduced risks associated with moderate alcohol consumption and higher social class.
VeriStem Technologies has developed an antibody that selectively targets and kills undifferentiated stem cells, reducing the risk of tumour formation. The company's Cellradication technology has the potential to revolutionize stem cell therapies and bring significant improvements to the healthcare industry.
A study published in Current Biology found that roosters' crowing is entrained to a circadian rhythm, meaning it follows a natural daily cycle. The researchers used constant light conditions and recorders to observe the birds' behavior, confirming that predawn crowing depends on an internal clock.
A new study reveals that critically ill very low birth weight (VLBW) infants are at high risk of hospital-acquired infections due to nurse understaffing. The research found that 13.9% of VLBW infants developed infections, resulting in increased mortality rates and long-term developmental issues.
Studies on the fruit fly Drosophila show that blind flies can't see due to histamine recycling in glial cells. Flies lacking Ebony and Tan genes have impaired vision, but those with Black mutations still struggle to see without histamine recycling. Further research is needed to understand the role of enzyme Black in vision.
A study suggests that humans rely on past experiences to predict future outcomes, which can lead to irrational decisions in games of chance. This strategy may contribute to problem gambling behavior and is resistant to current behavioral intervention strategies.
A new study has identified CA9, CD31, CD34 and VEGFR1/2 as potential biomarkers for predicting a good response to sunitinib treatment in patients with metastatic clear cell renal cell carcinoma. Patients with low Fuhrman grade tumors and high CA9 expression exhibited improved progression-free and overall survival.
A study found that pubic hair removal, particularly shaving, can increase the risk of spreading Molluscum contagiosum. Researchers believe micro trauma from hair removal facilitates transmission of the pox virus through self-infection or scratching.
A study published in Current Biology reveals that cliff swallows have decreased their mortality rates due to road collisions over the past three decades. The birds with longer-than-average wingspans are more likely to collide with vehicles, indicating that shorter-winged birds may be adapting to reduce fatalities.
A new Johns Hopkins Children's Center study reveals that peripheral intravenous catheters are nearly four times more likely to cause complications compared to centrally placed PICC lines. Clinicians should carefully weigh the ease of placement against the higher complication risk for non-central vein placement.
A team of researchers has created a map of gene 'shortcuts' between all human genes, simplifying the search for disease-causing mutations. This tool, called the human gene connectome, uses GPS-like principles to predict the distance and route between any two genes.
Researchers found that most medical subspecialty practices are unable to accommodate patients who use wheelchairs, citing transfer issues as the primary barrier. A new study suggests hydrochlorothiazide may be a safer treatment option than chlorthalidone for elderly patients with hypertension, due to its lower risk of electrolyte imbal...
A study conducted at Boston Medical Center found that IVC filters are often left in place indefinitely due to low retrieval rates and inconsistent anticoagulant use. A new multi-disciplinary team approach has been implemented to track and retrieve filters, resulting in successful removals of 10 out of 36 eligible filters.
Researchers found that elite athletes outperformed nonathletes in cognitive tests such as memory recall, task-switching, and peripheral vision detection. Female athletes also showed significant advantages over their male peers in certain tasks, minimizing the typical performance gap between women and men.
The AAN has released an evidence-based guideline for evaluating and managing athletes with suspected concussions. The new guideline emphasizes that any athlete suspected of experiencing a concussion should immediately be removed from play, and recommends concussion and return to play assessments be done individually. Athletes under hig...
Scientists discovered a correlation between adiponectin, a protein hormone from fat tissue, and migraine pain relief. The study found that increased levels of low molecular weight adiponectin were associated with reduced pain severity, while high molecular weight adiponectin was linked to increased pain.
The collaboration aims to accelerate the translation of Organs-on-Chips from benchtop to marketplace, providing more predictive and useful measures of drug efficacy and safety in humans. The Wyss Institute has developed over ten Organs-on-Chips, including lung, heart, liver, kidney, bone marrow, and gut-on-a-chip technologies.
Timothy Berners-Lee, British man and inventor of HTML language, receives the Queen Elizabeth Prize for his groundbreaking contributions to the development of the World Wide Web. The prize is the most highly endowed award in engineering science worldwide.
A recent Weizmann Institute study has discovered that caspase 8 signaling enzymes, which were previously thought to only induce programmed cell death, can also activate an entirely different process in certain cells - causing inflammation more directly. This finding highlights the need for further research into the signals transmitted ...
Researchers at the Max Planck Institute for Chemical Ecology discovered that insect odorant receptors are self-regulated, allowing them to amplify sensitivity in response to below-threshold odor stimulation. This mechanism enables flies to detect minute amounts of odors, essential for navigation and finding resources.
Researchers analyzed how particle shape affects the behavior of jammed materials, employing a computer algorithm to optimize shape configurations. The results were verified through large-scale 3D printed tests, providing insights into the complex interactions between particles and material properties.
The Thirty Meter Telescope will be the most powerful telescope ever constructed, allowing researchers to detect and study light from the earliest stars and galaxies. With NSF's support, the project aims to push the boundaries of scientific discovery in astronomy.
The article highlights how cultural norms influence parenting behaviors, with Western cultures emphasizing autonomy and many Asian, African, and Latino cultures valuing interdependence. Pediatricians can benefit from understanding these differences to provide culturally sensitive guidance and support.
A new study by Harvard T.H. Chan School of Public Health researchers found that hospital characteristics, not patient risk factors, influence c-section rates in Massachusetts. Hospital practices and culture play a significant role in determining c-section rates.
Researchers at Tufts University School of Medicine found that modifying astrocyte signals can limit the spread of damage after an ischemic brain stroke. By regulating neurotransmitter pathways, astrocytes play a critical role in the spread of damage following stroke.
The University of Miami's CSTARS has been awarded a contract by the Office of Naval Research to collect, process and disseminate global Synthetic Aperture Radar data in near-real time. This will enable the U.S. Navy to utilize SAR imagery for improved operational capabilities.
Researchers found that allogeneic hematopoietic stem cell transplantation with mesenchymal stem cells from third-party donors improved poor graft function in five patients with acute GVHD and two with chronic GVHD. The treatment also showed promise in reducing morbidity and mortality.
A longitudinal cohort study of 1,310 women found that even three years after being declared free of cancer, women who had a false-positive result consistently reported greater negative psychosocial consequences compared to women with normal test findings. Researchers propose annual blood pressure screening instead of checking at every ...
A new study published in Clinical Psychological Science found that adults suffering from complicated grief retain their ability to recall specific memories of their past when those events involve the deceased. They often generate impossible future scenarios with the deceased relative to their difficulty imagining a realistic future.
The study reveals that peripheral glaciers in Greenland are losing mass at a rate of up to 50 Gigatons per year, contributing to around 15-20% of sea-level rise. This is higher than expected and more significant than the ice sheet alone.
Retention forestry and agroforestry systems offer a balance between production and biodiversity conservation. The paper proposes bridging the two fields to enhance ecological benefits and species conservation.
Researchers developed biodegradable nanoparticles that selectively target and resolve inflammation, potentially treating atherosclerosis and neurodegenerative diseases. The nanoparticles release an inflammation-resolving peptide drug, promoting tissue repair and reducing chronic inflammation.
A large observational study found no significant association between maternal vitamin D levels and children's bone mineral content, suggesting that UK guidelines for vitamin D supplementation during pregnancy may be overstated.
Assistant professor of astronomy Misty Bentz will receive a five-year $862,769 NSF grant to measure distances to galaxies with known black hole masses and obtain clearer images of galaxies to predict black hole masses. This project aims to develop a shortcut for predicting black hole mass in any given galaxy through simple observations.
Researchers at Intermountain Medical Center have developed a real-time electronic screening tool to identify patients with pneumonia, speeding up diagnosis and treatment. The tool analyzes over 40 variables to determine the probability of pneumonia, alerting caregivers when necessary.
A Swedish study found significant heterogeneity in continence rates among patients after radical prostatectomy, suggesting that some receive suboptimal care. The research used multivariate models to evaluate surgeon variation and identified a negative correlation between potency and continence rates.