A study of Finnish twins found that adolescent drinking problems were strongly associated with adverse outcomes in early adulthood, including substance abuse, poor health, and relationship problems. The researchers controlled for genetic and environmental factors to isolate the causal effect of adolescent drinking on adult outcomes.
Researchers have found that cachexia, associated with cancer, is triggered by the conversion of white fat to brown fat tissue, a process also studied for obesity and diabetes. Blocking inflammation-promoting cytokine IL-6 can reduce cachexia symptoms.
Scharlach, a University of California at Berkeley professor, is recognized for his work on innovative programs to improve the lives of older adults. His research focuses on the physical and social contexts that contribute to positive outcomes for aging populations.
A new national study examines campus police/security responses to serious, underage, and less-serious alcohol incidents on and off college campuses. The study found that campus security or law enforcement officials rarely issue citations for alcohol-law violations, instead referring students to discipline or sanctions from other univer...
A study suggests that busier emergency centers may give the best chance of surviving life-threatening medical crises, with a 10% lower death rate compared to less busy centers. Patients with sepsis had a 26% lower death rate at busiest centers.
Researchers have found that groundwater reservoirs are being depleted at an increasing rate worldwide. A study by Prof. Petra Döll found that the rate of depletion is not as high as previously estimated, but still poses a significant threat to ecosystems and water resources.
New study finds orthopedic surgeries for patients aged 80+ generally safe, with significant decreases in mortality and complication rates. Spinal fusion, total knee replacement, and total hip replacement procedures show improved outcomes in patients without comorbidities.
Researchers estimate four to five large earthquakes occurred on the Seattle fault or related faults during the past 3,500 years. The study uses geologic data and new field evidence to reconstruct earthquake patterns in the Puget Lowland, a structurally complex region.
Scientists have identified a crucial region and pathway involved in the formation of the front-most portion of developing vertebrate embryos. The extreme anterior domain (EAD) orchestrates proper facial structure through signals that also affect adjacent regions, leading to significant defects when disrupted.
Researchers used an ultrafast optical laser and X-ray pulses to study the movement of electrons between atoms in exploding molecules. They observed that electrons can jump over surprisingly long distances, up to 10 times the length of the original molecule, shedding new light on microscopic dynamics.
A new study suggests that cancer metastasis, the spread of tumors from one part of the body to another, may occur through pure chance. Researchers used statistical models to show that 'common' cancer cells circulating in the bloodstream could, on rare occasions, cause metastasis.
Research reveals that white fat transforming into brown fat may stimulate weight gain and muscle strength in cancer patients suffering from cachexia. The browning process is triggered by inflammation, and anti-inflammatory therapies show promise in alleviating the condition.
A study of GRID2 gene mutations in spinocerebellar ataxia patients reveals no point mutations or insertion/deletion mutations. Instead, polymorphic deletions and single nucleotide variations were identified, with similar frequencies in patients and controls.
The collection contains about 2,000 clones of plant transcription factors, which can be used to improve plant traits such as cold resistance and seed quantity. The researchers hope that the library will help scientists understand how plants adapt to environmental changes and design more robust crops for future food security.
Researchers from NYU Langone will present new findings on tau immunotherapy and its potential for treating Alzheimer's disease. The presentations focus on the role of mitochondria and death receptors in amyloid toxicity, which may lead to improved treatment options for patients.
A new study suggests that improving food systems on specific regions and crops can boost global food security and protect the environment. The report identifies key leverage points for reducing environmental impacts and increasing food production in six countries: China, India, U.S., Brazil, Indonesia, and Pakistan. Closing the yield g...
A new study reveals that gut microbes metabolize carbohydrates, causing intestinal cell proliferation and tumor formation in mice genetically predisposed to colorectal cancer. Treatment with antibiotics or a low-carbohydrate diet significantly reduced tumors, suggesting these interventions could prevent this type of cancer in humans.
Researchers found that lipoic acid improved liver function and synchronized circadian rhythms in older animals, suggesting a potential breakthrough in understanding its benefits for human health. The study sheds light on the role of circadian rhythms in various biological processes and their dysfunction with age.
A study published in Journal of General Internal Medicine found that hour-long home coaching sessions and follow-up phone calls reduced re-admission odds by 39% among Medicare patients. The average cost of care was also reduced by $3,700 per patient.
A new study by NYU researchers found that African Americans and Latinos with HIV/AIDS face significant barriers to care, including fear of stigma and distrust of the medical system. Peer-recruitment was found to be nearly twice as effective as in-clinic recruitment for locating and engaging this vulnerable population.
The National Drug Early Warning System (NDEWS) will generate critically needed information about new drug trends in specific locations around the country. NDEWS will utilize social media and other innovative technologies to identify emerging drugs and trends, providing real-time information to experts and interested citizens.
A cross-disciplinary team proposes using gene drives to manage ecosystems, potentially combating malaria and other diseases. Gene drives can spread specified genetic alterations through targeted wild populations over many generations.
A recent study by Penn State researchers found that eating lean beef daily can effectively lower blood pressure in healthy individuals. The BOLD+ diet, which includes 5.4 ounces of lean beef per day, was more effective at reducing blood pressure compared to other diets tested.
A team of scientists at Cold Spring Harbor Laboratory has identified a gene called LIN-42 that controls the timing of events during development, governing a broad range of events throughout growth and behavior. The study provides insight into how species evolve without creating new genes.
Researchers have developed a method to stabilize microwave signals using laser beams as references, potentially replacing quartz crystals. This new technique, called electro-optical frequency division, enables stabilization of high-frequency signals with smaller devices, outperforming current electronic technology in some cases.
A study found that women who identify with their profession work more hours and spend less time with children, but have a more balanced childcare split. In contrast, men's paternal identity has no impact on childcare time or duties taken by mothers.
A GW researcher has discovered an antibody that recognizes ancestral fossil viruses in the human genome, providing a new target for HIV-1 immunotherapy. This breakthrough could help overcome the virus's frequent mutations and improve treatment options.
A potential biomarker associated with participants who experienced a more profound viral load reduction after receiving the vaccine has been identified. The biomarker, anti-C5/gp41732-744 antibody levels above 4μg/ml, may be able to predict which patients will benefit most from the therapeutic HIV vaccine candidate Vacc-4x.
Researchers from Scripps Florida have discovered a gene called Spns1 that plays a critical role in combating aging. The study found that manipulating the function of this gene can affect both developmental senescence and long-term biological aging.
Researchers simulate bubble universe collisions to predict observable signatures, ruling out certain models and providing a proof of principle for the multiverse hypothesis. By producing testable predictions, the multiverse model has crossed the line between appealing story and real science.
A new method using mRNA sequences has revolutionized the study of proteins in the African clawed frog, allowing for cost-effective proteomics experiments. The technique enables researchers to identify and estimate protein abundance with high accuracy, opening up new avenues for research in developmental biology and medicine.
Huntsman Cancer Institute will become a key partner in the National Clinical Trials Network, providing access to clinical trials for patients across the Intermountain West region. The institute's unique research assets, including the Utah Population Database and Center for Quantitative Imaging Excellence, will enable multi-institutiona...
EPFL researchers have developed a novel method to increase the accessible active sites of metal oxide catalysts in water splitting reactions, resulting in improved catalytic properties. The exfoliation method shows increased rates of up to 4.5-fold compared to conventional methods.
A team of scientists in China has developed a new type of perovskite solar cell that does not use a hole-transportation layer, showing high efficiency and stability. The innovation reduces production costs and paves the way for a cost-effective branch of development in this type of solar cell.
A study of 19,849 participants found that those with vision impairment had significantly lower employment rates, especially among women and younger individuals. Poor eyesight was also associated with a higher likelihood of not working due to its impact on income.
University of Houston researchers have developed a technique to extract biomolecules from live cells without killing them. The method uses magnetized carbon nanotubes to retrieve molecular information, allowing researchers to study single cells. This breakthrough could provide new avenues for diagnosing cancer and other diseases.
A crucial molecular key, Wnt5a, has been identified for healthy embryo implantation and pregnancy. Disruption of this signaling pathway can lead to infertility, miscarriage, or preterm birth.
A study from UMass Medical School found that older adults have two times the risk of falling while walking out of necessity than walking for recreation. The study also revealed that falls on sidewalks and streets are more likely to result in an injury, even with less walking distance.
Researchers found that H. pylori bacteria can rapidly detect minor injuries in the stomach and navigate toward them. The study shows how H. pylori causes disease by interfering with healing at these injury sites.
Researchers found that L-carnitine administration improved axon area, myelin sheath area, and numerical density of myelinated axons, suggesting neuroprotective effects on sciatic nerve crush injury in rats. These findings indicate potential benefits of L-carnitine for treating nerve damage.
Researchers tracked changes in gene activity when Western honey bees eat different diets, finding significant differences between those eating honey and those consuming sucrose or high-fructose corn syrup. Gene expression changes support the potential role of diet in maintaining bee health.
Scientists at Salk Institute identify gene DIXDC1 that stops cancer cells from spreading, opening new avenues for treating aggressive lung and other cancers. The discovery provides hope for patients with limited treatment options.
Researchers at Harvard University studied 137 varieties of cheese from 10 countries to identify three general types of microbial communities. These findings provide a model for studying microbial communities and their interactions, with potential applications in understanding various biological processes. The study also reveals the imp...
A decade of research led by Dr. Tak Mak identified PLK4 as a promising therapeutic target for breast cancer treatment and developed a small molecule inhibitor to block it. The study showed significant antitumor activity in preclinical models, offering hope for personalized cancer medicine.
The three institutions are working together to develop less painful treatments for babies with fused skulls, reducing the need for annual surgeries. Researchers have established a Craniofacial Anomalies Registry and plan to expand their collaboration to include postdoctoral fellows and graduate students.
US Department of Education reforms place demands on principals' expertise and time; new report recommends coaching teachers, redesigning job descriptions, and university partnerships to support principals. Effective principal training is crucial to implementing stronger teacher evaluation systems, according to researchers.
A recent study published in JAMA Psychiatry has identified the risk factors for post-traumatic stress disorder (PTSD) after an accident. The research found that 9% of injured people develop PTSD, with symptoms such as headaches, pain, and anxiety persisting for months after the incident.
Researchers have experimentally re-created conditions deep inside giant planets like Jupiter and Saturn using the National Ignition Facility. They successfully compressed diamond to unprecedented densities, providing new constraints for dense matter theories and planet evolution models.
New research suggests that combining energy drinks with alcohol can increase the urge to keep drinking. Study participants who consumed A+EDs had higher ratings of liking and wanting to drink more than those in an alcohol-only condition. The findings highlight concerns about energy drink consumption among young adults.
A large international study has found that overall death rates among HIV-positive adults have almost halved since 1999, while deaths due to AIDS-related causes and cardiovascular disease have declined significantly. Non-AIDS cancers remain a leading cause of non-AIDS deaths in people with HIV.
Researchers have developed a promising new approach to editing gene transcripts, which uses targeted oligonucleotide drugs. This technique has already shown promise in treating diseases such as Duchenne Muscular Dystrophy and spinal muscular atrophy.
Typhoon Rammasun brought heavy rainfall over the Philippines, with total rainfall estimates exceeding 325 mm, according to NASA's TRMM satellite analysis. The storm made its way towards Hainan Island, China, with forecasters predicting landfall on July 18.
A groundbreaking study by Harvard University researchers shows that orb-weaver spiders do not share a single origin, contrary to long-held popular opinion. The study's findings suggest that the orb web evolved independently in two groups of spiders, with distinct behaviors and silk characteristics.
Researchers at Drexel University and Temple University found that the introduction of SugarHouse Casino had no significant impact on violent street felonies, vehicle crime, residential burglary, or drug crimes in the immediate neighborhood. Crime rates were largely unaffected, with some displacement to surrounding areas observed.
A recent study found racial and ethnic disparities in alcohol services utilization among women, with Latina and Black women showing lower rates of treatment. This disparity highlights the need for targeted outreach programs to address the unique needs of female minority drinkers.
A study of 6,800 outpatients found antiviral therapy was given to only 19% of those at high risk for complications, while antibiotics were prescribed to 30%. The findings suggest a need for increased education on appropriate use in outpatient settings.
A team of researchers from Kansas State University has completed a chromosome-based draft of the wheat genome, providing a valuable resource for plant science researchers and breeders. The genetic blueprint will enable the rapid location of specific genes controlling complex traits such as yield, grain quality, and disease resistance.
The study reveals that two kinases, Plk1 and CDK, work together to ensure precise CENP-A replenishment at centromeres. Incorrect timing of this process can lead to chromosome segregation failure, resulting in cell death or disease.
Researchers at the University of Delaware have identified a protein called HSP70 that helps stabilize NOD2, a key protein involved in Crohn's disease. This finding provides a possible pathway for developing an effective therapy for the inflammatory bowel disease.
A new paper from the University of Toronto suggests that gender quotas are more effective in countries with tight cultural norms, where people prioritize obedience and conformity. In contrast, loose cultures may struggle to implement policies due to disagreements over how to translate egalitarian principles into practice.