Researchers have developed a novel treatment approach for persistent viral infections like herpes by blocking the activity of host cell protein LSD1, reducing HSV infection, shedding, and recurrence. This epigenetic therapy shows promise as an antiviral strategy to control shedding and reactivation of latent virus.
Aarhus University leads a new EUR 8 million European research project to develop a new form of interaction between physical objects and their computer control. The technology aims to make it easier to create credible cyber-physical systems, which are crucial for industry's ability to innovate.
A new study reveals that suburban blacks and Hispanics live in poverty-stricken neighborhoods with lower test scores compared to their white and Asian counterparts. The research, part of the US2010 Project, highlights the persistent disparities in suburban segregation and unequal access to resources.
Scientists have developed a system that can identify chemicals in the atmosphere from up to one kilometer away. The technique uses terahertz radiation and an infrared laser to detect toxic gases, including nerve gas, chemical spills, and industrial pollutants.
A new model called empathic partnership aims to create safe and effective partnerships between primary care practitioners and their patients. The framework encourages caregivers to adopt six key elements: reflection, environment, language, knowledge, partnership, and empathy.
Hepatitis B virus (HBV) infection is associated with a complex tumor microenvironment in hepatocellular carcinoma (HCC), leading to carcinogenic progression. Targeted therapies targeting the microenvironment offer promise for treating this disease.
Physician-researcher Sumeet Chugh receives $2.36 million grant to develop prevention strategies for sudden cardiac arrest. The study focuses on patients aged 35-59 years old and aims to identify risk factors, including sex hormones and genetics.
Researchers demonstrate that β relaxations are intrinsic to supercooled liquids and glasses, connecting them to outstanding issues in glassy physics and material sciences. The study suggests that metallic glasses could be used to design glassy materials with specific properties, such as ductility.
A new study by Dr. Danny Ben-Shahar and Roni Golan found a correlation between personality traits and individual real estate choices, with neurotic individuals opting for homeownership over renting. The research also showed that local 'personality types' in America are associated with statewide real estate trends.
Researchers at UC Irvine found that small drainpipes at enclosed ocean bays produce high fecal counts during summer months, impacting calmer waters. The team suggests green remedies like bioswales and drought-inspired reductions in irrigation runoff to capture urban slobber before it reaches drains.
A new computer-based approach to treating anxiety sensitivity has shown significant results in reducing suicide risk. The Cognitive Anxiety Sensitivity Treatment (CAST) is a 45-minute online program that provides interactive features and exercises to improve responses to stress and anxiety.
A study at Plymouth University is exploring how proteins interact to build up in nerve cells, potentially leading to dementia diseases like Alzheimer's and Parkinson's. The research aims to understand the mechanism behind protein deposits and may one day lead to new therapies for patients with dementia with Lewy bodies.
Researchers found that great tits learn new foraging techniques by observing others in their social network, adopting the dominant behavior and creating a stable tradition. Even when birds discover multiple methods, they tend to conform to the majority behavior, passing it down to the next generation.
Researchers investigate why Kentucky children are prescribed psychotropic medications at a higher rate than the national average. The study aims to identify patterns and potential causes, with a focus on improving care for vulnerable children.
Case studies of high-functioning individuals with ASD and gender dysphoria reveal complexities in providing psychotherapy for these patients. Suggested techniques offer hope for helping them explore their gender identities and potentially benefiting from gender transition.
Research finds that physically active children outperform their inactive peers in the classroom and on tests of achievement. Physical activity is associated with larger brain volumes, increased concentration, and enhanced attention spans.
A groundbreaking study published in Nano Letters describes a revolutionary novel device that has the potential to treat a number of eye diseases. The proof-of-concept artificial retina is more efficient, flexible, and can stimulate neurons more effectively than previous designs.
Non-Tea Party Republicans' views on science and environmental issues are closer to those of Independents than Tea Party supporters, according to new research. The study found significant divisions between Tea Party supporters and Republicans, but fewer divisions between non-Tea Party Republicans and Independents.
A new study highlights the importance of inclusive reef management policies to address unequal access to reef benefits. Coral reefs provide essential resources such as food and income opportunities, but not everyone has equal access to them.
A Swedish-US research team analyzed over 1.8 million births to find that maternal overweight and obesity increase infant mortality risk, with grade 2-3 obesity linked to more than doubled infant deaths. The study found modest increased risks for overweight mothers and significant increases for those with severe obesity.
Researchers at the Walter and Eliza Hall Institute discovered that inflammatory skin diseases such as psoriasis are linked to abnormal apoptosis, while necroptosis is associated with systemic inflammation. This finding could lead to the development of new treatments for these conditions.
Researchers have developed a highly accurate airborne hygrometer, HAI, which simultaneously measures the amount of water present in the atmosphere as vapour, condensation, droplets, or ice. The device provides precise data on natural and anthropogenic cloud formation processes and their influence on climate development.
A new study found that the fungus responsible for white-nose syndrome, which causes bat populations to crash, can infect nearly every bat in a colony during hibernation. Bats that survive the winter can clear the infection after they become active again, but this leads to high mortality rates at the end of winter.
Researchers at the University of Illinois have developed a cheap, hydrolysable polymer called poly(hindered urea)s (PHUs), which can be designed to degrade over time. This material has potential applications in drug delivery, tissue engineering, and packaging, offering advantages over traditional hydrolyzable polymers.
Researchers at Salk Institute discover that confining caloric consumption to an 8- to 12-hour period can significantly reduce weight gain, improve body composition, and even reverse obesity and diabetes in mice. The study's findings add to mounting evidence highlighting the importance of time-restricted eating for overall health.
Research from Northwestern University found that heavier newborns have higher test scores from third through eighth grade. Even among twins, heavier-born twins have higher average test scores. However, other factors such as maternal education can be a larger predictor of academic achievement.
Researchers found that tens of thousands of small impacts could efficiently jettison Earth's entire primordial atmosphere, while giant impacts would be less effective. The team's calculations suggest that the early Earth was likely devoid of its original atmosphere, with Venus and Mars also experiencing significant atmospheric loss.
Tropical Storm Hagupit has become a Category One typhoon with maximum sustained winds near 70 knots, posing threats to islands in Micronesia. The storm is expected to continue moving west-northwest through the region and intensify before weakening on December 6.
A study by Cancer Research UK found that people often dismiss cancer symptoms as less serious and attribute them to other causes. Only two per cent thought cancer was a possible cause, despite experiencing red-flag symptoms such as unexplained coughs or persistent changes in bowel habits.
Researchers at Max Planck Institute of Psychiatry developed the first potent and highly selective inhibitor of FKBP51, called SAFit-ligand. This inhibitor enhances neuronal cell growth and improves stress-coping behavior in mice, providing a structural and functional basis for mechanistically novel antidepressant treatment.
Research highlights the surge of infectious disease in northern latitudes, driven by climate change and close contact between species. The study also explores the use of accelerometers to track an animal's internal state, including emotions and diseases.
A study published in Molecular Psychiatry has identified a network of genes associated with alcohol dependence. The researchers found that certain sets of genes were co-expressed together in individuals who consumed the most alcohol, but not in non-alcoholics. This discovery could lead to better screenings and treatments for alcoholism.
Researchers funded by the National Institutes of Health are unraveling the mystery of how blue light from artificial lighting and electronic devices disrupts the human body's natural circadian rhythms. The study aims to understand the chemical basis for this disruption, which can lead to health problems such as sleep disorders, cancer ...
A study of US Marines who suffered concussions found persistent post-concussive symptoms and lingering cognitive effects are due to concussion-related brain trauma. Multiple concussions were associated with worse emotional and post-concussive symptoms, an important finding for military and civilian settings.
A novel gene knock-in technique using PITCh enables accurate and efficient insertion of exogenous genes into human cells, silkworms, frogs, and other organisms. This method overcomes technical hurdles associated with homologous recombination in cultured cells and organisms.
Millions die each year from obesity-related issues, with Australia projected to be third fattest nation by 2020. Fitness facilities can mitigate risks by implementing pre-activity screening, automated defibrillators, regular inspections, and staff training.
Human sex trafficking is a significant public health issue affecting the US, with an estimated 600,000 to 800,000 victims worldwide annually. The average age of entry into the sex trade for children is between 12 and 14, with lasting mental and physical health consequences.
Researchers used a new endocrine-based approach to determine the age at sexual maturity for wild stocks of western Atlantic bluefin tuna, finding they mature at a considerably younger age than currently assumed. This discovery could lead to changes in fisheries scientists' estimates of population size.
The Office of Naval Research has developed an automated process to make F-35 canopies, saving $125 million over the life of the program. The new method uses a control system with cameras to ensure uniform shape formation and eliminates worker exposure to hot ovens.
A study by Carnegie Institution scientists Katharine Ricke and Ken Caldeira found that climate warming caused by a single carbon emission reaches its maximum effect within 10 years. This refutes the common misconception of decades-long delays and benefits current generations, not just future ones.
New research reveals that baby corals can acclimate to increased atmospheric carbon dioxide levels, potentially mitigating the impact of ocean acidification. This finding suggests that staghorn corals, traditionally considered stress-tolerant, may have a limited ability to adapt.
A new study suggests that organic carbon traces found in a Martian meteorite may have originated from biological sources. The researchers argue that the carbon content was deposited in the meteorite's fissures before it left Mars, and its isotopic ratio is consistent with biological origin.
The study reveals that the Amundsen Sea Embayment in West Antarctica is losing ice at an incredible rate, with the total amount of loss averaging 83 gigatons per year. This is equivalent to Mt. Everest's worth of water weight lost every two years over the past 21 years.
Researchers identified 150,000 sequence motifs that could adopt the G4 DNA structure, suggesting a functional role in gene regulation. These elements are strategically placed throughout the chromosomes and may help plants cope with environmental stresses.
A new study found that diabetic patients with even mild coronary artery disease are at a comparable risk of heart attacks and major adverse events to those with severe obstructive disease. Researchers used cardiac computed tomography angiography data from 14,000 patients to evaluate long-term prognostic value in diabetic patients.
A team of researchers will assess the ability of Nanotrap technology to detect Ebola virus in saliva, offering a safer and more accurate testing method. The project aims to address the dire need for better testing methods for Ebola, using non-invasive saliva collection and highly sensitive diagnostic tests.
Researchers developed game-theoretical model to examine different incentive schemes, finding rewarding cooperative agents first leads to higher cooperation levels. The optimal strategy shifts to punishing wrongdoers after a sufficiently large proportion of agents cooperate, promoting highest level of cooperation at lowest cost.
Researchers have devised a powerful technique that simultaneously determines nanoscale materials' chemical makeup and topography, improving spatial resolution to 2 nm. This breakthrough enables chemically imaging of nanoscale materials with direct chemical sensitivity.
Breast cancer patients undergoing chemotherapy and immediate breast reconstruction are at risk of thrombotic complications, which can delay or modify reconstructive plans. In some cases, these complications require anticoagulation therapy and may necessitate additional surgeries.
Louisiana Tech University has been awarded a $1.45 million grant to produce more highly-effective secondary math and science teachers through the UTeach program, which aims to address the need for qualified STEM educators. The university will work with partners to increase the number of highly-qualified STEM teachers in the region.
International research confirms King Richard III's identity to 99.999% accuracy using DNA and genealogical study. The study also reveals his likely appearance, including almost certainly blue eyes and probably blond hair, as seen in the Arched-Frame Portrait.
A study from Concordia University reveals that male millennials need specific emotional prods to engage with non-profits, unlike female millennials who respond to causes on an emotional level. Marketers must focus on the benefits of supporting a cause to successfully engage millennials in charitable efforts.
A team of scientists has created a synthetic surface that can control the adhesion of E. coli bacteria using light. By switching on and off specific wavelengths, researchers can reverseorientate carbohydrate structures to influence bacterial bonding.
The Prolaris test could save the healthcare system $6 billion over 10 years by reducing costs and improving health outcomes. The test improves health outcomes, reduces healthcare costs, and aids physicians in providing clinical care for their patients.
Scientists have identified a range of new chemicals with potent anti-malarial properties that could lead to new treatments for the disease. The compounds block a molecular salt pump at the surface of the parasite, causing it to swell and burst.
Researchers at Max Planck Institute of Molecular Physiology studied the three-dimensional structure of the ryanodine receptor using electron cryo-microscopy and a new technique for detecting electrons. The high-resolution structure reveals how the protein changes its shape upon binding calcium ions.
A study by Julia Day found that occupants who had effective training in using the features of their high-performance buildings were more satisfied with their work environments. The study, which examined over 50 high-performance buildings across the US, highlighted the importance of creating a culture focused on conservation.
Researchers found that online activism did force the Chinese government to take some actions on air pollution, but corporate and government interests largely shaped the online discussion. The study shows both the power and limits of online activism in China, highlighting the need for more nuanced approaches to addressing complex social...
A large study by UC Davis researchers found that patients of different racial and ethnic backgrounds reported experiencing differing treatment approaches from medical providers, including referrals to mental-health care and medications. Asian-Americans were the least likely to be assessed or counseled for mental-health problems, while ...
The University of Chicago is establishing the nation's most comprehensive computational facility to store and harmonize cancer genomic data, expanding access for scientists. The Genomic Data Commons will provide an interactive system for researchers to analyze and identify potential therapeutic targets.