A study found that juvenile detainees with multiple psychiatric disorders are at high risk for developing new disorders five years after release from detention. Almost 27% of males and 14% of females had two or more psychiatric disorders five years later.
Researchers from Aarhus University developed a comprehensive overview of gene interactions in muscles, providing insights into the effects of exercise on metabolism. The study's results, published in Scientific Data, offer a platform for future research into diseases like diabetes and obesity.
Scientists at Forschungszentrum Juelich re-measured the van der Waals force for single molecules, revealing a superlinear increase with growing molecular size. The study highlights the importance of van der Waals forces in biomolecules and adhesives, such as geckos' ability to climb smooth walls.
A team of researchers from the University of Florida has developed a process to convert human waste into rocket fuel, producing 290 liters of methane per crew per day. This anaerobic digester process can also produce non-potable water and hydrogen, offering a sustainable solution for space missions and potentially on Earth.
Researchers revised classical enzymatic theory by incorporating long-lasting protein-water coupled motions into models of functional catalysis. The study revealed a new biological phenomenon where water motions adapt to substrate binding, critical for effective binding.
A new study led by Brown University found that older adults learn and retain visual perception tasks as well as younger people, but struggle to filter out irrelevant information. The researchers suggest this may be due to the brain's tendency to learn more than necessary, leading to a 'plasticity and stability dilemma'.
Researchers at Lund University discover that proteins in the lens of the eye convert from a fluid to a glassy state, leading to reduced mobility and potential cataract formation. This transition may be responsible for age-related long-sightedness.
A new study identifies TET1 as a master regulator in cancer progression by silencing tumor suppressor genes. Adding TET1 back to cancer cells reactivates these genes, reducing abnormal proliferation.
Recent research suggests that moderate coffee consumption may lower the risk of Alzheimer's disease by up to 20 percent. This protective effect is attributed to compounds such as polyphenols, which are also found in high quantities in coffee.
A team of researchers from the University of the Basque Country has analyzed the most suitable configurations to minimize delays in multi-hop Bluetooth networks. The study found that permanent node connections result in minimal delay, while varying delay between one hop and another.
The new coating material radiates infrared light directly into space while also reflecting sunlight, resulting in cooler buildings that require less air conditioning. The technology has the potential to reduce energy consumption and meet skyrocketing demand for cooling in urban areas.
Researchers have developed a comprehensive cognitive test battery, Cognition, to measure the impact of spaceflight stressors on astronauts' cognition. The 10-test battery will be administered to the first astronaut on the International Space Station on November 28.
A £120 million investment will fuel the development of secure communication technologies, leveraging quantum physics to transform data security and transactions. The Quantum Communications Hub brings together world-leading researchers from top UK universities, with potential applications in healthcare, communications, and security.
A new study suggests that prehistoric conflict played a crucial role in the evolution of humans' ability to work together, overcoming costs associated with large brains. The research proposes that warfare and 'us vs. them' activities drove the emergence of high intelligence and cooperative behavior.
Researchers from Chongqing University have discovered a new method to compress laser linewidth based on Rayleigh backscattering, achieving ultra-narrow linewidths of hundreds of hertz. This breakthrough enables the development of portable laser devices with precise optical signals, revolutionizing fields like spectroscopy and sensing.
Researchers have described the intricate relationships within a biological wastewater treatment plant in unprecedented detail. This study provides new insights into the laws governing bacterial function, with potential applications in medicine and environmental conservation.
A clinical trial confirms the external artificial pancreas system improves glucose control and reduces the risk of hypoglycemia compared to conventional diabetes treatment. The dual-hormone artificial pancreas provides additional reduction in hypoglycemia, offering a promising treatment option for type 1 diabetes patients.
Researchers used iPS cells to correct genetic mutations in Duchenne muscular dystrophy (DMD), a severe muscular degenerative disease. Engineered nucleases TALEN and CRISPR were successfully used to edit the genome of iPS cells generated from DMD patient skin cells, resulting in the disappearance of the mutation responsible for DMD.
A promising immunotherapy drug, MPDL3280A, shows improved efficacy in patients whose immune cells initially attack cancer but are shut down by PD-L1. Researchers found that tumor expression of PD-L1 in surrounding immune cells is a key indicator of response to the treatment.
Researchers at UNL pinpoint characteristics of laser pulses that can control electron behavior, enabling predictive and controlled electron motion. The study's findings offer a new signature for classifying experimentally produced laser pulses.
Women's sport coverage in the UK press remains underrepresented, with only 5% of total sports coverage dedicated to women's sport. This marginalization leaves girls with fewer role models, resulting in lower participation rates and potential health problems related to obesity.
Researchers found dogs process human speech in left- and right-hemisphere biases, similar to humans. Dogs respond differently to familiar commands and intonation cues, suggesting they pay attention to both who and how we communicate.
Researchers have developed a robotic fish prototype with advanced flexibility, inspired by Anguilliform fish. The device can swim forward, backward, and turn using artificial intelligence and torques applied to its joints.
Researchers identified specific circuits in the brain where memories are generated, using a precision MRI technique that tracked information flow within the brain. The study aims to gain new insights into how Alzheimer's disease affects the brain and memory processing.
Research found teens with traumatic brain injury (TBI) are two to four times more likely to drink alcohol, use cannabis, or abuse other drugs compared to peers without a history of TBI. Specifically, teens with TBI reported higher rates of using crystal meth.
Researchers at Carnegie Mellon University used fMRI scans to analyze brain activity while eight people read a chapter of Harry Potter. The result was the first integrated computational model of reading, identifying which parts of the brain are responsible for parsing sentences and determining word meaning.
Researchers at Stanford University School of Medicine have discovered an enzyme that repairs damaged DNA but can also cause destruction. The study found that endonucleases, which are attracted to DNA/RNA hybrids, cut the DNA and damage it when present.
Researchers discovered lactate plays a key role in ASPS tumor cells' behavior, fueling their growth and aggressiveness. The study also confirms the fusion gene ASPSCR1-TFE3 as the driver of this rare cancer.
The Van Allen radiation belts contain a nearly impenetrable barrier that prevents the fastest, most energetic electrons from reaching Earth. The discovery was made using NASA's Van Allen Probes, which study the region and provide accurate measurements of high-energy electrons for the first time.
A team led by University of Colorado Boulder discovered an invisible shield in the Van Allen radiation belts that blocks ultrafast electrons, threatening astronauts and space systems. The barrier is thought to be maintained by Earth's magnetic field or plasmaspheric hiss.
A new study by the University of Michigan found that more than half of seniors with signs of dementia haven't received a medical evaluation. The study suggests that as many as 1.8 million Americans over 70 with dementia are not being evaluated for cognitive symptoms, which can lead to modifiable causes of thinking or memory impairment.
Scientists from Queen Mary University of London have developed a new therapy for advanced bladder cancer, showing significant tumor shrinkage in patients. The treatment, MPDL3280A, has been given breakthrough therapy designation status by the US FDA and has promising results in a phase one clinical trial.
Saint Louis University researcher Daniela Salvemini and colleagues have discovered a way to block a pain pathway in animal models of chronic neuropathic pain, suggesting a promising new approach to pain relief. Activating the A3 adenosine receptor subtype provides robust pain reduction across several types of pain.
A world-first breakthrough drug therapy for treating battle casualties is being developed by James Cook University scientists in Australia, with potential to save thousands of soldiers' lives and has widespread civilian applications.
A team of scientists has developed a new way to measure precise distances to galaxies tens of millions of light years away, using the W. M. Keck Observatory. By measuring the physical size of a dusty ring around supermassive black holes, they calculated the distance to the galaxy NGC 4151 with only 10% uncertainty. This method has the ...
The study reveals the complex relationships within a model ecosystem, with implications for protecting the environment and human health. The researchers found that Microthrix parvicella, a generalist bacterium, can adapt to various living conditions and dominate the wastewater treatment plant ecosystem.
Scientists at Max F. Perutz Laboratories have elucidated the molecular structure and regulation of α-actinin, a crucial muscle protein. The findings provide unprecedented insights into the protein's mode of action and its role in muscle disorders, paving the way for improved treatments.
Researchers at Drexel University have developed a conductive clay that can be easily molded into various shapes and sizes, representing a significant shift in the production of electrodes for energy storage devices. The clay's high conductivity and plasticity make it an attractive candidate for use in batteries and supercapacitors.
Researchers found that plasmid DNA attached to a rocket exterior survived suborbital spaceflight, re-entry, and landing conditions. The study showed that up to 53% of the DNA retained its full biological function, with 35% remaining functional after heating up to 1000°C.
A breakthrough in atomic memory technology allows for reliable quantum information storage and transmission over long distances. The device can store light with multiple spatial modes, enabling higher capacity and paving the way for widespread adoption of quantum communications.
A recent study published in ecancermedicalscience found that cimetidine, an over-the-counter medication, can increase survival rates in colorectal cancer. The ReDO project aims to repurpose other common medicines for cancer treatment, offering promising alternatives to expensive anti-cancer drugs.
Researchers found that the time spent by a drunken sailor on a square with streetlamps is constant regardless of the lamp density. This effect also applies to light waves in disordered media, rubber balls rolling across a plank, and even ant paths, revealing a universal phenomenon.
A £600,000 grant from Cancer Research UK will fund a research study investigating the efficacy of BTK inhibiting drugs in treating mantle cell lymphoma. The trial will compare these new drugs to standard chemotherapy and aim to improve life expectancy and quality of life for patients.
A study published in PLOS ONE found that individuals buried as potential 'vampires' in 17th-18th century Poland were likely local residents. The research used radiogenic strontium isotope ratios to determine the origin of the individuals, and the results suggested a predominantly local population. This suggests that these burials may h...
Researchers studied molecular tools to understand the influence of the Isthmus of Panama on freshwater shrimps. The results showed that sister species remained genetically isolated despite potential crossing through a channel.
Medical experts call for radical improvements in UK liver disease treatment and detection, citing a 'postcode lottery' for patients. The commission recommends increasing specialist centers and improving primary care services to address excessive alcohol use and obesity.
Researchers have developed a new vaccine strategy that targets unique features of cancer cells, enabling the immune system to destroy or drive into remission tumors. The vaccines, which use samples of DNA from patient tumors and normal tissue, have shown promising results in computer simulations, cell cultures, and animal models.
The GOCE satellite provided accurate gravity field measurements, enabling scientists to image the planet in a new way. Researchers are sharpening the picture of our dynamic planet with studies in geophysics, ocean circulation, climate change, and civil engineering.
University of Minnesota engineers have developed a novel device platform that generates and confines both sound wave and light wave on a computer chip. This technology has the potential to improve wireless communications systems using optical fibers and could be used for computation using quantum physics.
Researchers found that combining imagery with observation strengthens brain activity in movement-related areas, potentially aiding motor function recovery for stroke patients. The technique may help compensate for lost brain functions through brain plasticity.
A UT Arlington researcher has won a $200,000 grant to screen Hispanic patients for depression and provide education on the disease and its treatment options. The project aims to dispel myths and reduce stigma associated with mental health care among Hispanics.
Researchers developed LipoLLA, a therapeutic nanoparticle containing linolenic acid that effectively kills Helicobacter pylori bacteria in mice. The treatment also reduced inflammation and was non-toxic, making it a promising alternative to standard antibiotics.
A multidisciplinary team from UTMB will lead projects to determine the drug safety and efficacy of an antiretroviral-releasing intravaginal ring. The project aims to develop a device that can deliver multiple-drug combinations of HIV antiretroviral drugs, which is crucial for preventing the spread of sexually transmitted HIV in women.
A study found that pharmaceutical companies failed to comply with FDA recommendations for pivotal drug study design and primary outcomes in nearly a quarter of cases. The researchers suggested that mandatory FDA review of pivotal trial protocols could optimize study quality.
A new study published in the journal Diabetes shows that a chemical produced in the pancreas, gamma-aminobutryic acid (GABA), can prevent and reverse Type 1 diabetes in mice with human beta cells transplanted into their bodies. GABA also improved the survival rate of pancreatic cells during transplantation.
Scientists at KU Leuven successfully converted cellulose in sawdust into hydrocarbon chains, which can be used as an additive in gasoline or component in plastics. The conversion process is a new type of bio-refining and has potential economic benefits, offering an alternative to traditional fossil fuels.
Researchers at the University of Leeds have identified a missing gene mutation linked to autistic traits in mice. The study found behavioural features similar to autism symptoms, including sociability issues and impaired neurotransmitter release.
Concordia University's Lean Aerospace Value Streams project aims to minimize waste and increase value in Canada's aerospace sector. Researchers will apply lean principles to design, manufacturing, and supply chain processes.
Researchers fabricated a new substance from atomic sheets that interlock like Lego toy bricks, offering potential for next-generation materials. The material, made of graphene and tungsten disulfide, combines the good properties of each component layer, enabling efficient solar cells and flexible electronics.
Researchers discover PHD3 controls EGFR uptake, leading to uncontrolled cell growth and tumor proliferation. PHD3 loss is crucial for human malignant brain tumour growth under hypoxia.