A Phase I study of a combination ARV vaginal ring found the ring safe and effective in preventing HIV infection, with dapivirine showing promising results. However, maraviroc, the first entry inhibitor tested as a microbicide, was not as effective and requires further development.
A study published in the European Heart Journal reveals a nearly fivefold increased risk for heart attack in the two hours following an angry outburst. The researchers found that patients with cardiovascular events were more likely to have experienced anger immediately prior to the event.
Research finds that HIV transmissions within communities are often facilitated by sexual contact with partners from outside the community. The study, conducted in Uganda, analyzed data from 46 communities and found that most new infections occur through sex with an outsider.
A collaborative study by McGill University researchers found that cortical thickness is linked to changes in full-scale IQ, contradicting earlier assumptions. The study discovered significant increases or decreases in IQ were associated with exaggerated or normal cortical thinning, respectively.
Researchers discovered a significant correlation between exposure to Mexican drug war violence and anxiety symptoms on social media. Citizens' posts showed decreased levels of negative affect after prolonged exposure to violence, highlighting the desensitization effect.
New research confirms Arctic ice trends show a five-day per decade increase in the length of the melt season, with implications for climate change tracking and shipping. The study's findings also highlight the importance of understanding Arctic sea ice feedback mechanisms.
A recent study analyzed nearly 24,000 active human research clinical trials and found that 5-16% are not covered by two major federal regulations. The primary federal human subjects protections policies in the US include FDA HSP regulations and the Common Rule, which can lead to overlap trials and gap trials with varying characteristics.
Scientists at Scripps Research Institute develop new probes to detect functional, normally folded, and disease-associated misfolded conformations of proteins in cells. The technology paves the way for discovering new drugs for misfolding diseases such as Alzheimer's and Parkinson's.
Researchers at Saarland University have developed a novel therapeutic approach called optokinetic stimulation therapy (OKS) that has been shown to improve perception of sounds and images in stroke patients. After undergoing OKS therapy, patients were able to better perceive people, objects, and spatial orientation.
Two studies suggest that low protein intake may be beneficial for longevity until old age, while high-protein diets are associated with increased cancer risk and mortality. High-quality protein with low fat and complex carbohydrates is recommended for optimal health and long life.
A new study published in the American Journal of Lifestyle Medicine reveals that canned foods deliver on nutrition and cost, making them a high-quality option for Americans to meet their dietary needs. Canned fruits and vegetables provide great tasting, safe options, with no sacrifices in nutritional quality.
Researchers at the University of Basel successfully pulled isolated molecular chains from a gold surface using atomic force microscopy. The experiment revealed the detachment force and binding energy of molecules, providing new insights into the mechanical behavior of single polymers.
Two studies found that homosexuals and bisexuals are more likely to be victims of intimate partner violence, with a risk compounded by childhood abuse. Non-heterosexual victims were also more likely to experience substance abuse and health issues compared to heterosexual victims.
A research team developed an adjuvant that optimizes lentivirus gene transfer by enhancing virus attachment to target cells, resulting in a three-fold increase in transduction rate. This improvement reduces the need for additional viruses, potentially leading to more effective treatments for genetic disorders.
The spiral galaxy ESO 137-001 is zooming through the Norma cluster at nearly 4.5 million miles per hour, stripping gas from its home and forming new stars in intergalactic space. Astronomers hope that studying this galaxy can help them understand how galaxies form stars and evolve over time.
Researchers at the University of Cincinnati have identified a zero-dimensional quantum dot structure that can confine electronic excitations within semiconductor nanowires. This discovery has significant implications for harnessing solar energy, creating stronger lasers, and developing more sensitive medical diagnostic devices.
A recent study found that warfarin treatment is associated with a lower risk of death, heart attack, or stroke without an increased risk of bleeding for patients with established cardiovascular disease and atrial fibrillation. The study included over 24,000 patients with kidney function measured through serum creatinine levels.
A multi-institutional team, led by Rachel Whitaker, studies host-viral interactions to understand how viruses can protect hosts from competitors and aid in survival. The research aims to develop a theoretical model of eco-evolutionary dynamics between viruses and microbes.
A new study found that children with attention deficit hyperactivity disorder (ADHD) are more likely to become obese and sedentary teenagers. The research followed almost 7000 children in Finland and found those with ADHD symptoms at age eight had significantly higher odds of being obese at age 16.
Research suggests that terminally ill cancer patients who receive chemotherapy in the last months of life are more likely to undergo intensive medical care and die in an intensive care unit. The study highlights the importance of end-of-life discussions between patients and physicians.
A recent study revisits the phenomenon of 'gaydar' in women, finding that lesbians are better at detecting sexual orientation, while straight women excel at identifying emotions and thoughts. The research also highlights differences in judgments between lesbian and straight judges.
Brandeis University researchers have identified the correct structure of a potassium ion channel in heart cells, challenging previous studies that suggested varying numbers of proteins were required. The findings have significant implications for understanding arrhythmias and developing effective treatments.
A recent analysis found that frequent experiences of racism were associated with a higher risk of obesity among African American women. Women who reported consistently high experiences of racism over a 12-year period were 69% more likely to become obese compared to those in the lowest category.
Research at Umeå University and University of Antwerp found that alien plants successfully penetrate alpine vegetation in subarctic mountain areas. Human transportation on roads and walking tracks facilitates their invasion. Climate warming also contributes to the success of introduced species.
Researchers at Georgetown University Medical Center have discovered that a small region within the amygdala in bats is responsible for producing emotional calls and sounds. This finding may lead to new treatments for malfunctions in emotional responses, such as pathological aggression.
Johns Hopkins researchers have identified a set of genes that can be turned back on to evade immune detection in ovarian, breast, and colorectal cancer. Reversing these epigenetic changes with an FDA-approved drug allows cancer cells to become more vulnerable to immune therapy, potentially leading to more effective treatment.
A team of Swedish researchers led by Professor Mats Brännström have successfully performed nine uterus transplants using live donors, a breakthrough in treating uterine infertility. The transplants involved five mother-daughter pairs and four close relatives, with no blood transfusions required during surgery.
A national study of Taiwanese youth found that adolescents who start having sex at a young age tend to exhibit externalizing problems like rule-breaking and aggressive behavior. This is especially true for females and those with same-sex partners.
A study found that exposure to passive smoke in childhood causes direct and irreversible damage to the structure of children's arteries. Children exposed to both parents' smoking have thicker artery walls, increasing their risk of heart disease and stroke. The study supports banning smoking in cars where young people are present.
Researchers have found a link between prostate cancer aggressiveness and cholesteryl ester accumulation, suggesting new diagnostic and treatment methods. The study also shows that drugs previously developed to treat atherosclerosis might be repurposed for advanced prostate cancer treatment.
Researchers at the University of Edinburgh's Roslin Institute have created working nerve cells from horse stem cells, paving the way for cell therapies targeting neurological conditions. The breakthrough could also benefit horses affected by grass sickness, a previously untreatable condition.
Astronomers have developed a new method to gauge exoplanet pressure by detecting dimer molecules. This technique may also help identify biosignatures of life in extraterrestrial atmospheres. The discovery could be made possible with future powerful telescopes like the James Webb Space Telescope.
Tropical cyclone Faxai reached typhoon strength with maximum sustained winds near 65 knots/74.8 mph on March 4. The NASA Aqua satellite captured an image of the storm, showing tightly wrapped bands of thunderstorms around its center. Forecasters predict Faxai will maintain typhoon strength for a day before weakening.
A team of researchers used computer simulations to study the aerodynamics of flying snakes, discovering that whirls of wind surrounding the snake's body provide an extra boost of lift. This unique shape helps the snake glide efficiently through the air, making it a fascinating example of nature's efficient design.
Researchers analyzed data from the VOICE trial and found that women using injectable contraceptive DMPA were more likely to acquire HIV than those using NET-EN. The study also showed a significant difference in HIV risk between DMPA and NET-EN users, particularly among HSV-2 positive women.
Scientists have discovered a molecular 'switch' that regulates heart cell division and could potentially be used to regenerate damaged heart tissue. The discovery was made by studying infant siblings with a rare heart defect, who exhibited unusual heart cell proliferation.
Eating a diet rich in animal proteins during middle age may be as deadly as smoking, according to a new study. High-protein diets were linked to a dramatic rise in cancer mortality and an increased risk of early death.
Cornell research reveals that natural enemies like ladybeetles can delay pest resistance to Bt crops, reducing the need for multiple genes and refuge plants. This finding supports the use of Bt crops in agriculture while minimizing pesticide usage.
The New Guinea flatworm, considered one of the 100 worst invasive alien species, has been found in France for the first time. The flatworm was identified by molecular analysis and is capable of consuming European snails and other soil-dwelling species.
Researchers have discovered a plant-based compound that targets the root cause of spinal muscular atrophy (SMA), a genetic disorder causing muscle wastage and weakness in infants. Quercetin has shown promise in tests on zebra fish, mice, and fruit flies, offering a potential treatment option for early stages of the disease.
Researchers from North Carolina State University have developed a new security tool called Practical Root Exploit Containment (PREC) to detect and contain malware that attempts root exploits in Android devices. PREC targets code written in the C programming language, reducing false positives and making anomaly detection more practical.
A new study by Ben Marzeion and Anders Levermann finds that global warming will put 136 cultural monuments at risk, including historical cities like Bruges, Naples, and Istanbul. Sea-level rise will impact not only coastal areas but also regions currently populated by millions of people, leading to the loss of culture and heritage.
The study found that seven per cent of the current global population would be living on land that would be below sea level if temperatures increased above pre-industrial levels by 3°C in the next 2000 years. The impact on cultural heritage sites, including iconic landmarks like the Statue of Liberty and Sydney Opera House, is severe.
Research links intimate partner violence in men who have sex with men to negative health indicators such as alcohol use, depressive symptoms, HIV positivity, and unprotected sex. The study found a lifetime rate of exposure to IPV among MSM was 48%.
A major new study found that pre-enlistment mental disorders are a significant risk factor for suicidal ideation among US soldiers. The study, which surveyed over 975,000 Army personnel, reveals that nearly 60% of soldier suicide attempts can be traced to these conditions, with the vast majority developing them before enlistment.
A recent study published on bmj.com found that the HPV vaccine significantly protects against cervical abnormalities in young women. The research estimated that three doses of the vaccine provided 46% protection against high-grade cervical abnormalities and 34% protection against other cervical abnormalities.
A new study suggests that male hormones, such as testosterone, play an important role in female fertility and may enhance IVF success rates. The research found that male hormones promote follicle development by preventing cell death and increasing sensitivity to follicle-stimulating hormone.
Research suggests that palliative chemotherapy can lead to more invasive medical procedures and a higher risk of death in intensive care units among advanced cancer patients. The findings highlight the need for clearer discussion of the harms and benefits of palliative chemotherapy at the end of life.
DVT can lead to post-thrombotic syndrome, causing chronic leg pain, fatigue, swelling, and skin ulcers; interventional radiologists offer minimally invasive treatments to prevent this complication
Dr. Richard Glassock, a member of LA BioMed's Board of Directors, has been awarded the 2014 Medal of Excellence for his exceptional contributions to patient care. He is recognized for his extensive research and clinical expertise in glomerular diseases and clinical nephrology.
A study reveals that military fathers returning from combat deployment struggle to reconnect with their young children, who may not remember them. The researchers emphasize the need for support and resources to help these families rebuild their relationships.
A systematic review found that prenatal and postnatal interventions, duration, and mother emotional support are critical factors in promoting exclusive breastfeeding. The study suggests that more support and interventions in the postpartum period may be necessary to achieve the international goal of exclusive breastfeeding for six months.
A team of scientists tracked 17 loggerhead turtles for 27 to 220 days, providing the first look at their early behavior and movements in the wild. The study's findings challenge previously held beliefs, suggesting that young turtles may drop out of currents into the middle of the Atlantic or the Sargasso Sea.
New USDA guidelines have increased consumption of fruits and vegetables among low-income students without leading to an increase in food waste. Students now select a fruit or vegetable as part of their lunch, resulting in improved nutrition.
Fossils from the Middle-Upper Jurassic Period in northeastern China have revealed an exceptional window into life approximately 160 million years ago. The Daohugou Biota contains superbly preserved specimens of a diverse group of amphibian, mammal and reptile species.
A recent study by CHOP researcher Brendan J. Keating found that higher BMI raises the risk of type 2 diabetes and high blood pressure, while another study identified genetic signals linked to central adiposity. These findings have significant implications for the obesity pandemic in the US and other countries.
A new HIV/STI prevention program in Haiti is changing lives by empowering marginalized women to become health workers. The program increased HIV and STI knowledge, condom use, and decreased depression rates among participants.
Researchers have found that a plant pigment called quercetin could help prevent nerve damage associated with spinal muscular atrophy (SMA), a leading genetic cause of death in children. Quercetin was shown to significantly improve health of nerve and muscle cells in tests on zebrafish, flies, and mice.
In the Central African Republic, stock-outs of antiretroviral drugs have led to mistrust among patients and reduced treatment adherence. The country's HIV-infected population of over 220,000 faces significant challenges in accessing life-saving medication.
Research reveals that seminal plasma enhances bacterial movement, promoting infection; increased bacterial density on human epithelial cells also facilitate infection. More than 100 million new gonorrhea cases annually worldwide.