A recent study in Human Vaccines & Immunotherapeutics found that two doses of the HPV-16/18 AS04-adjuvanted vaccine Cervarix are non-inferior to three doses, providing similar protection against cervical cancer. The two-dose schedule showed a clinically acceptable safety profile and induced strong antibody responses.
Researchers analyzed the Chile earthquake of February 2010, finding that fluid pressure in rocks affects earthquake rupture processes. The study revealed that mechanical coupling between plates controls stress build-up and seismic energy release, with fluid pressure variations linked to subduction zone dynamics.
A recent study published in the Journal of Epidemiology and Public Health found that being underweight increases the risk of death for both adults and fetuses. Adults with a BMI under 18.5 are 1.8 times more likely to die than those with a normal BMI, while obesity is associated with a 1.2-1.3 times higher risk of mortality.
People who are married have lower rates of several cardiovascular diseases compared to those who are single, divorced, or widowed. Married individuals were found to be 5% less likely to have any vascular disease and had lower odds of other vascular conditions.
A new study published in the Journal of Sexual Medicine found that 29% of men with erectile dysfunction were able to reverse their condition through lifestyle changes. The study highlights the importance of addressing risk factors such as obesity, alcohol intake, and sleep disorders to improve sexual health.
Researchers have developed perovskite solar cells that excel at absorbing and emitting light, with a remarkable 70% efficiency rate. These 'wonder cells' can also produce cheap lasers, opening up new applications in telecommunications and light-emitting devices.
A study found that women who ate a diet high in fruits and vegetables as young adults were less likely to have plaque build-up in their arteries 20 years later. In contrast, men did not show the same benefit. The study's findings support the importance of developing healthy eating habits early in life.
Research suggests that high TV time is associated with poorer food choices and increased cardiovascular risk in middle schoolers. Kids who watched TV for two to six hours a day were more likely to eat high-fat foods like French fries and chips.
A large-scale survey of 3.5 million Americans found that married people have a significantly lower risk of heart disease than singles, divorced, or widowed individuals. The study also revealed age-related differences in cardiovascular disease risk among married couples.
Researchers developed a predictive tool that analyzes gene expression changes to predict patient survival. The tool, based on mouse studies, has shown promise in predicting treatment risk for early-stage breast cancer and certain lung cancers.
Research suggests that women with four or more children are at increased risk of cardiovascular disease, with a two-fold higher risk of abnormal coronary artery calcium scores and aortic wall thickness. This association remains even after adjusting for socioeconomic factors, education, race, and known risk factors.
A new UK research center will focus on developing advanced chemical products worth £200 billion to the economy. The Centre for Doctoral Training in Complex Particulate Products and Processes will train researchers to develop people who can go out there and continue the UK's leadership in this field.
A study of 12,712 children found that 30% had borderline or elevated total cholesterol, underscoring the importance of universal pediatric cholesterol screening. The findings suggest that adopting healthy lifestyle choices and regular screening can potentially stall vascular changes and reduce future disease risk.
Chemists at Ruhr-Universität Bochum have completely analyzed the Terahertz spectrum of dissolved glycine in water, revealing its motion and disproving a long-standing theory. The study used spectroscopy and molecular-dynamics simulations to track the amino acid's movement in an aqueous solution.
A systematic review and meta-analysis found that obesity intervention programs lowered children's blood pressure, with healthy eating and physical activity promoting the most effective results. The study suggests that early intervention can help prevent long-term health consequences.
Pediatricians Rebecca H. Buckley and Jennifer M. Puck received the March of Dimes Lifetime Achievement Award in Genetics for laying the groundwork for early detection of severe combined immunodeficiency disease (SCID). Their research led to the development of a newborn screening test, significantly improving long-term survival rates.
Researchers estimate that up to 100% of lung cancer patients experience sexual dysfunction, which can persist after treatment. Experts call for open discussions and specialized help from healthcare professionals to address these issues.
Researchers suggest aspartic acid could serve as a biomarker for postoperative cognitive dysfunction, based on correlation analysis between changes in hippocampal metabolites and cognitive impairment in aged rats. The study aims to identify potential biomarkers for predicting postoperative cognitive dysfunction.
Research reveals endocrine disrupting chemicals cause feminization in male thick-lipped grey mullet; 60-91% of males show vitellogenin and Aromatase Cyp19a1b gene expression, indicating feminization. Estuaries across Basque coast show high levels of pollutants contributing to the phenomenon.
Researchers from NUS have developed a novel fluorescent sensor, GHB Orange, to identify the presence of gamma-hydroxybutyric acid (GHB) in beverages. The sensor can detect GHB in under 30 seconds, making it a valuable tool for preventing drug-facilitated sexual assault.
A study by the University of Southampton found that Autumn is becoming significantly later in the year, while Spring is arriving slightly earlier. The researchers analyzed satellite imagery and vegetation data to identify changes in vegetation growth cycles, finding a delay in Autumn's onset.
Engineers have developed a multilayered waveguide taper array that can absorb light across different frequencies, boosting the efficiency of solar power and thermal energy recycling. This technology has potential applications in stealth technology and waste heat recycling.
A new study suggests that infants who experience near-death events (ALTEs) have abnormal regulation of esophageal and airway function. The research found that these infants are more likely to have pauses in breathing, gasping breaths, and difficulty coordinating swallowing and respiratory interactions.
Researchers at Tufts University have demonstrated an environmentally friendly process to generate nanostructures from silk using water as a developing agent. This approach provides a green alternative to conventional synthetic polymers and delivers fabrication quality comparable to conventional methods.
Researchers investigated percutaneous microballoon compression for trigeminal neuralgia, finding that a 2-minute compression period can suppress pain transduction. However, long-term compression is ideal for patients with recurrent trigeminal neuralgia to reduce complications and increase success rates.
Researchers found Gulf War veterans with impaired mitochondrial function had significantly delayed phosphocreatine recovery after exercise, a robust marker of mitochondrial dysfunction. Impaired mitochondrial function accounts for Gulf War illness symptoms like fatigue, cognitive challenges, muscle problems, and exercise intolerance.
Researchers at Johns Hopkins Medicine have developed a computerized process that enhances image-based guidance in minimally invasive surgery, potentially replacing conventional tracking systems. The new system achieves high accuracy, often exceeding 2 millimeters, while using low-dose radiation, making it suitable for various procedures.
Disadvantaged children attending high-quality early childhood programs exhibit improved health outcomes as adults, including lower cardiovascular and metabolic disease risks. These findings support the importance of early intervention in preventing costly adult chronic diseases.
Researchers found that individuals with high 'justice sensitivity' are driven by cognitive reasoning rather than emotion when evaluating morally good or bad behavior. This suggests that the search for justice is fueled by analysis and mental calculation rather than sentimental motivations.
Researchers investigate why only 14 percent of woodrat hybrids have genetic signatures from both desert and Bryant's woodrats. Habitat differences and mating conflicts are found to be key factors limiting hybridization in closely-related species.
Researchers identified a new mechanism linking genetic variation to heart disease risk by disrupting the interaction between a developmental gene and a specialized type of RNA. This discovery expands understanding of complex disease risk and potential drug targets for cardiovascular disease.
Dr. Tu's research identified a unique nutritional pathway in mammalian cells crucial to cancer cell growth, which he hopes will lead to new treatments for human disease. He received the award for his work expanding our understanding of metabolism's role in cellular processes.
A recent study found that individuals with diabetes who experience major depressive symptoms are at a significantly higher risk of developing kidney failure. In contrast, minor depressive symptoms were not found to have a significant association with kidney disease development.
NASA's Hubble Space Telescope captured an image of Mars-bound comet Siding Spring, revealing two jets of dust emanating from the nucleus. This observation will help astronomers determine the direction of the nucleus's pole and axis of rotation.
Banning smoking in public places has been shown to cut premature births by 10% globally, according to a comprehensive study published in The Lancet. The research also found a 10% fall in hospital attendances for childhood asthma attacks in regions with anti-smoking laws.
Researchers at Århus University used X-ray light to track the growth of tungsten oxide nanoparticles, which can be tailored for smart windows and solar cells. The study shows that nanoparticles form from octahedra units in solution and develop a predominantly ordered crystal structure as they grow.
A large-scale study found that cholesterol levels tend to be worse in the colder months compared to warmer months, with significant variations in lipid profiles. The researchers speculate that behaviors such as reduced sun exposure and lower vitamin D levels during winter may contribute to these seasonal fluctuations.
A Rice University analysis of state implementation plans reveals that most urban areas have met the next benchmark for reducing airborne particulate matter. The study found that PM 2.5 concentrations declined by an average 2.6 micrograms per cubic meter in regions that filed SIPs to attain the standard by 2009.
UCSF researchers found that breast tissue stiffening in cancer development leads to tumor progression, triggering the production of a molecule associated with worse clinical outcomes. The discovery may lead to more accurate prognosis and new treatment strategies targeting structural changes in breast cancers.
Researchers have made a computer app to spot and decode the unique footprints in yeast DNA, revealing an intricately choreographed dance of ribosomal RNA genes. This discovery enables biologists to track evolutionary relationships between different species using these tiny changes.
Researchers at the University of Dundee have identified a critical chemical messenger that protects brain cells against Parkinson's disease. The discovery of phospho-ubiquitin suggests it may be possible to develop drugs to switch on Parkin enzyme by mimicking this molecule, offering new avenues for treatment.
Research shows that vitamin D deficiency is associated with higher prevalence and severity of coronary artery disease. Patients with low vitamin D levels are at a higher risk of developing severe heart disease, and the study suggests that vitamin D may be beneficial in preventing heart disease.
Researchers created logical circuits using living slime molds, which can process information and carry out Boolean logic operations. The slime mold-based system could potentially be used to build low-cost, biological computing devices and sensors.
Researchers from the University of Edinburgh found that newborn male deer with high testosterone levels are less likely to survive their first year compared to peers. The study also showed that testosterone levels in offspring are linked to their mother's condition, suggesting a potential survival advantage for younger calves.
Researchers have discovered that zebrafish regenerates its caudal fin by a process involving V-ATPase, which pumps hydrogen ions to generate an electrical current. This finding has implications for understanding adult tissue regeneration and developing new therapeutic strategies.
Researchers have found a potential target for treating mitochondrial disorders, a condition that affects cellular energy production. The study suggests that blocking the gene ATPIF1 may be therapeutic in rescuing cells from mitochondrial dysfunction.
The CHAMPION PHOENIX trial found cangrelor significantly reduces stent thrombosis (ST) at 48 hours and 30 days, associated with lower mortality. Cangrelor also improves freedom from ST at 30 days in various categories of ST.
A study by Simon Fraser University ecologist Anne Salomon warns of a declining natural history research and use in academia, government agencies and non-government organizations. Natural history collections have stopped expanding since 1990, but it remains vital for making wise management and conservation decisions.
A study analyzing 300 summer Arctic sea ice forecasts found that predictions are accurate when conditions follow the observed downward trend, but less so when they deviate from it. Improving forecasting by incorporating sea ice thickness and concentration data may enhance seasonal predictions.
IRC Researchers discover a new function of AID, an enzyme crucial for the immune response. This finding helps explain hyper-IgM syndrome type 2 (HIGM2), a rare genetic disorder that causes an immunodeficiency syndrome.
A recent study found that US adults are unwilling to accept soda taxes and portion size restrictions, but support adding front-of-package nutrition labels in schools. The survey of 1,319 adults revealed a strong positive relationship between years of education and policy support for reducing sugar-sweetened beverage consumption.
Research from Oregon State University reveals two distinct pathways for the connection between religion, spirituality, and health. Formal religious affiliation and service attendance are linked to better health habits, while meditation and private prayer regulate emotions and physiological effects.
Researchers found significant differences between men and women in heart rate responses to exercise. A new formula takes these nuances into account, providing a more accurate estimate of peak heart rate. The updated formula helps optimize workouts and improve test results for both men and women.
Researchers found that acupuncture/electroacupuncture combined with Seroxat improves depressive symptoms and reduces obsessive-compulsive and anxiety symptoms. The treatment produces a rapid onset of therapeutic effect.
Researchers from Children's Hospital Oakland Research Institute successfully mapped genome methylation in the fruit fly Drosophila melanogaster. The study, published in Genome Research, found that DNA methylation occurs at specific short motifs and is independent of DNMT2 activity.
Researchers at MIT have developed a new system that selectively filters light waves based on their direction of propagation. The technique, which uses a stack of ultrathin layers with precise thickness control, could improve efficiency in solar photovoltaics, detector systems for telescopes and microscopes, and display screens.
Research by Cold Spring Harbor Laboratory finds that early-life chronic stress can cause anxiety, depression, and decreased social interaction in adulthood. In contrast, young mice subjected to social defeat stress showed resilience, but still experienced increased aggression as adults.
A US study found clusters of 'broken heart' syndrome in Vermont and Missouri after major natural disasters, suggesting stress as a trigger. Researchers call for greater awareness among emergency responders to improve diagnosis and treatment of the condition.
A new study by North Carolina State University and other institutions found that online gaming supplements social behavior, rather than replacing it. Researchers observed thousands of gamers at public events and conducted in-depth surveys to conclude that gaming is a social activity that complements offline interactions.
Researchers found that rotavirus infection activates specific immune cells, including dendritic cells and T cells, which can recognize and destroy insulin-producing islet cells. This 'bystander activation' contributes to the acceleration of autoimmune diabetes in a mouse model.