Researchers have identified a key role for the FAK molecule in controlling breast cancer stem cell survival and predicting disease recurrence. Blocking FAK activity with a new drug significantly improved treatment outcomes, suggesting a potential method to predict which patients are most likely to experience recurrence.
A study found that older men are three times less likely than women to undergo osteoporosis screening and treatment after a broken wrist. This disparity increases the risk of future bone breaks and related complications in men, who already have twice the mortality rate of women following a hip fracture.
Researchers developed a compact probe that produces detailed images of blood vessels using ultrasound and photoacoustic imaging modalities. The system enables real-time imaging and can reveal important medical information, such as hemoglobin oxygen saturation, for monitoring tumor progression.
A new study by UMass Amherst scientists predicts a significant increase in grass pollen production and allergen exposure due to climate change, with potential impacts on human health. The researchers found that elevated CO2 stimulates pollen production, leading to increased exposure for individuals with grass pollen allergies.
A recent study by Christopher Ferguson found no association between media violence consumption and societal violence rates. However, violent video game consumption was strongly correlated with declines in youth violence rates.
Allocating $45-76 billion to protected areas annually could help manage them effectively, ensuring their contribution to the planet's well-being is met. Many threatened species and plants rely on well-managed protected areas for survival.
The National Institutes of Health (NIH) has provided $26 million in funding to continue and expand the DIAN-TU trial, a large-scale clinical trial aimed at identifying drugs to stop or slow Alzheimer's disease. The trial is focused on dominantly inherited forms of Alzheimer's disease and will test two treatments in patients with inheri...
Researchers at the University of Copenhagen found that a high-fat diet can postpone signs of brain aging in mice with a defective DNA repair system. This could lead to new treatment possibilities for children with Cockayne syndrome and patients with Alzheimer's and Parkinson's disease.
VTT's innovative magnetometer is significantly cheaper than traditional technology and less sensitive to external magnetic fields. This makes it suitable for applications such as magnetoencephalography in neuroimaging, mining industry, industrial quality control and security.
Researchers found that prenatal exposure to polycyclic aromatic hydrocarbons (PAH) raised the odds of behavior problems associated with ADHD at age 9. Children born to mothers exposed to high levels of PAH during pregnancy had five times the odds of inattentive-type ADHD compared to those whose mothers did not have high PAH exposure.
A new class of conjugated polymers has been discovered, approaching disorder-free limits and enabling faster, more efficient flexible electronics. These materials could be used to create lightweight, flexible displays for smartphones and tablets.
A new study reveals a dietary supplement, KoACT, outperforms calcium and vitamin D in preventing bone loss. Women in early menopause experience rapid bone loss, making this finding crucial for their health.
A new screening tool, based on nine clinical variables, helps identify high-risk patients before heart procedures, allowing for strategies to avoid bleeding complications. This led to a significant reduction in post-procedure complications, including the need for blood transfusions, across Allina Health hospitals.
Researchers develop composite material that harnesses visible light to degrade endocrine disruptors, including BPA and phenol, in a promising breakthrough. The method offers a more efficient alternative to existing ultraviolet light-based approaches.
The US Forest Service advocates for a holistic approach to managing wildfires, considering both ecological and human dimensions. Strategies include adopting land use regulations, developing locally appropriate vegetation management strategies, and improving evacuation planning and household plans.
A study of over 20,000 noninvasive and minimally invasive cosmetic procedures found a low incidence of adverse events, with most being minor and rapidly remitting. The procedure types most commonly associated with adverse events were those on the cheeks, nasolabial lines, and eyelids.
Researchers found that people prefer leaders with a healthy complexion, regardless of intelligence level, except for situations requiring negotiation or exploration. A study of 148 participants revealed that health is the most important trait when selecting a leader, surpassing intelligence as an optional extra.
A new study suggests that the role of public utility commissions and the National Labor Relations Act in labor disputes regarding electric utilities need to be reexamined. The study's author argues that modifying the NLRA could help change the mindset of both labor and management, and ensure that public safety is prioritized.
The Catoca diamond mine in Angola revealed 118 million-year-old dinosaur and crocodile tracks, with the largest mammalian track attributed to a raccoon-sized animal. No fossil bones or teeth of such an animal have been found elsewhere in Africa or the world.
A recent study found that pediatricians often fail to inform parents of overweight Latino children, highlighting the challenges of addressing rising obesity rates among minority youth. The study recommends using family-preferred terms when discussing weight with Latino families.
GWATCH provides a secure platform for researchers to access and share protected human data for disease gene discovery. The platform offers a dynamic visualization tool that enables researchers to identify disease-associated genetic markers without risking patient privacy.
Scientists are developing low-cost air-cleaning devices to replace expensive metals like platinum and palladium. Recent studies have shown promising results in improving indoor air quality, potentially alleviating symptoms of 'sick-building syndrome'
Researchers have discovered that inhibiting a particular mitochondrial fission protein could reverse Parkinson's Disease symptoms by reducing cell death and dopamine release deficits. This study offers exciting potential for an effective treatment and paves the way for future studies in this field.
Researchers at the University of Illinois have created a new online tool to study postnatal brain growth in human infants based on similarities with the piglet brain. The tool, an MRI-based brain atlas for four-week-old piglets, offers a three-dimensional averaged brain and anatomical regions of interest.
A recent study from Vanderbilt University Medical Center found that a child's ability to distinguish musical rhythm is related to their capacity for understanding grammar. The study, led by Reyna Gordon, suggests that rhythm could be used as an indicator of grammar skills in children with language disorders.
A new analysis of current evidence suggests that expensive and cheaper drugs both work well in easing diabetes nerve pain. Considering the significant cost difference between medications, doctors should prioritize cost when prescribing treatments for diabetic neuropathy until more studies are done.
Fidel Santamaria and his team aim to transform traditional approaches to understanding brain networks using a power-law framework. They will build computational tools to analyze and model power-law dynamics at multiple scales, from molecules to behavior.
A multicenter study led by Boston Children's Hospital found that implementing the I-PASS bundle can reduce hospital medical errors by 30%, improving safety and quality of care. The study was conducted at nine medical centers, where healthcare providers used a standardized communication system to share patient information.
Women with complete androgen insensitivity syndrome (CAIS) have brain responses similar to those of typical women when viewing sexual images, a new study reveals. This finding supports the theory that androgens are key to masculine responses, and suggests CAIS individuals are psychologically typical despite having a Y chromosome.
Researchers found that bald and golden eagles in North America have dangerously high levels of polybrominated diphenyl ethers (PBDEs) in their livers, with concentrations highest near urban areas. The study suggests a range of exposure to these toxic chemicals, with more research needed to understand trends and accumulation patterns.
A study of nearly 38,000 patients found that those diagnosed with nonobstructive coronary artery disease (CAD) had a significantly increased risk of heart attack or death one year after diagnosis. Patients with nonobstructive CAD had an associated risk of MI that was 2-to 4.5-fold greater than among those with no apparent CAD.
Researchers found that teenagers who placed high importance on both work and family goals, as well as having confidence in achieving them, were more likely to report feeling successful in their careers and families later in life. These individuals also reached higher education levels than those with only family-oriented goals.
Scientists have developed a topical microbicide loaded with hyaluronic acid nanofibers that could potentially prevent HIV transmission. The delivery system is triggered by semen fluid and provides prolonged retention at the target site, reducing discomfort.
A new study using forensic DNA tests successfully identified the species of venomous snakes that bit people 100% of the time. The test has the potential to improve care for patients affected by deadly snakebites in countries where this is a major health risk.
A new analysis reveals that the design and aesthetics of classrooms can significantly impact student learning and success. Researchers recommend structural improvements and cues signaling valued learners to facilitate student growth.
Researchers at Lund University discovered that lactose intolerant people are at a reduced risk of developing lung, breast, and ovarian cancers. The study, which analyzed nationwide data from Sweden, suggests that diet plays a crucial role in protecting against these cancers.
Researchers discovered that Ebola and Marburg viruses edit their genetic material by adding extra nucleotides to their RNA. This process, known as RNA editing, was previously unknown in these viruses and could lead to a better understanding of their biology and the development of new treatments.
A team of researchers from the University of Pittsburgh found that individuals who generate creative solutions tend to build on existing ideas rather than using unrelated concepts. The study, published in Design Studies, collected data from over 350 participants and showed that ideas closely related to a problem were more likely to be ...
Scientists discovered eight shared molecular pathways and several key driver genes in Type 2 diabetes and cardiovascular disease. These findings suggest that treating the two conditions together could be effective, with potential therapeutic targets identified.
Researchers analyzed NYC lot data to conclude the city has a significantly smaller rat population than previously believed. The estimated 2 million rat count is a more conservative assessment than the widely-cited 8 million figure.
A new study revealed that 43% of nursing students engage in hazardous alcohol consumption, with significant variations among demographic groups. Hazardous drinkers were more likely to be young, smoke, and live outside family settings.
Researchers found that four destructive pests are identical, leading to improved international cooperation in pest management. The identification of these pests as a single species will also lead to more effective quarantine measures and reduced barriers to international trade.
A study found that conflict roots in misunderstanding of rival group's motivation, correcting this through financial incentives can improve conflict resolution. Researchers found a link between attributing wrong motivations and unwillingness to negotiate.
New research reveals that gut bacteria convert red meat's L-carnitine into trimethylamine-N-oxide, a compound promoting atherosclerosis. Gamma-butyrobetaine, another metabolite produced by gut bacteria, also contributes to cardiovascular risk.
A study from Johns Hopkins Medicine found that performance is influenced by a person's aversion to loss, with those having high loss aversion doing better when faced with large prospective losses but choking under pressure of large gains. Brain imaging revealed the ventral striatum as the key brain area involved in this process.
A trial revealed that patients with a specific type of esophageal cancer who received the lung cancer drug gefitinib survived longer, with some patients living up to six months beyond their initial treatment. The drug has shown promise as a targeted treatment for this disease.
Researchers used coronary computed tomography angiography (CCTA) to detect high-risk coronary artery plaque and non-alcoholic fatty liver disease (NAFLD), a condition characterized by abnormal liver function. The study found that NAFLD is associated with high-risk plaque, even after adjusting for traditional risk factors.
Researchers have created a new material that can detect explosives and toxic gases in seconds, offering four advantages over current detectors: sensitivity, accuracy, speed, and cost-effectiveness. The breakthrough could lead to flexible solar panels and improved public safety.
A Concordia University study reveals that hybrid fish become genetically robust like their purely wild counterparts within a few generations, providing hope for conservation efforts. This finding has implications beyond fish, with similar conclusions drawn about wolf species previously exposed to hybridization.
A new study by Rice University researchers reveals lemurs play a crucial role in dispersing seeds for trees, increasing survival rates. The findings highlight the importance of preserving lemur populations to maintain the health of Madagascar's rainforests.
Polar bears use scent associated with their paws to convey information about their social status and reproductive readiness. The study suggests that climate change could disrupt this vital communication method, impacting the animals' ability to reproduce successfully.
Researchers found high rates of individuals testing positive for Chagas disease and related heart disease in Texas, with rates 50 times higher than CDC estimates. The study aims to increase awareness and diagnosis of this emerging infectious disease in the southern United States.
The US Army and NREL have validated energy savings for net zero energy installations, reducing energy consumption by 25% and annual costs by up to $300 million. Six pilot sites achieved net zero energy, with varying approaches to energy efficiency and renewable energy production.
A Virginia Tech graduate student has received a U.S. Environmental Protection Agency fellowship to study the effects of mercury contamination on red-winged blackbird populations. Her research aims to investigate how stress hormones and disease are connected in birds, with potential implications for understanding avian malaria infections.
A new analysis identifies 15 distinct social media uses during disasters, including providing preparedness information and reconnecting community members. The proposed framework aims to standardize and organize disaster social media practices, potentially protecting lives and aiding recovery
EBioMedicine brings together worlds of basic research and clinical science in an open-access journal with Cell Press and The Lancet editorial influence. The journal prioritizes rapid publication and publishes a range of research study types, including commentaries and viewpoints.
Researchers at UT Arlington are developing tissue-engineered artificial lymph nodes that can attract prostate cancer cells, allowing for more targeted treatments and potentially longer patient survival. The technology, led by Liping Tang, could also help identify the biological signals that enable cancer to migrate throughout the body.
Researchers discovered a counterintuitive effect where structural disorder counters thermal disorder in certain systems, leading to lower overall disorder. The study focused on charged fluids and found that disordered charges interact strongly with mobile ions to oppose the effects of thermal disorder.
The latest version of the Sensor Fish measures more forces and costs about 80% less than its predecessor. It will help further reduce the environmental impact of hydropower by accurately measuring forces fish feel as they pass through turbines and structures in conventional dams and other hydro power facilities.
Temple University School of Medicine has received a $100,000 Grand Challenges Explorations grant to develop a non-invasive maternal blood test that predicts abnormal fetal neurodevelopment. The project aims to identify biomarkers in maternal blood that can predict healthy fetal brain development and guide interventions.