Researchers developed a technique to target and quantify breast cancer segments in a single cell using gold nanoparticles tagged with synthetic DNA. The method measures the unique signal produced when light interacts with the nanoparticles, allowing for accurate diagnosis and potential personalized treatment options.
Researchers at Michigan Medicine have found that BET bromodomain protein 4 binds to the hormone androgen receptor, making it a potential target for prostate cancer treatment. The study suggests that a drug targeting this protein could work even when prostate cancer becomes resistant to current therapies.
Research suggests that cognitive reserve, the brain's ability to adapt and compensate for injury, plays a role in recovery from traumatic brain injury. Those with higher educational attainment are more likely to achieve full recovery, with nearly 40% of patients with 16 or more years of education fully recovering.
A Michigan State University researcher found that software-generated partners can be effective motivators during exercise, outperforming 'no buddy' conditions. The study, published in the Games for Health Journal, suggests potential applications for fitness game developers and may improve exercise outcomes.
A recent study found that 1.5 million US high school basketball players were treated for injuries, with 42% of teams not having an athletic trainer on site. The study calls for increased access to on-site trainers to properly assess and treat injuries.
Researchers found that ravens can deduce the rank relations of individuals in their own group as well as neighboring groups. They exhibited stress-related behaviors when encountering unexpected dominance reversals. This cognitive ability is similar to that of primates and suggests a complex social intelligence.
Researchers have discovered that the timing and coordination of cell division are crucial for normal development, particularly in early embryonic stages. Fast-dividing cells require genes without introns to efficiently produce proteins.
A new study from the University of Waterloo reveals that reading picture books with toddlers exposes them to sophisticated information about animals in a way that allows children to apply this knowledge broadly. Moms use generics and provide facts about animals when reading picture book stories.
Researchers at Princeton University found that 30-40% of US households live hand-to-mouth, but many are not the poorest in terms of income or net worth. The 'wealthy hand-to-mouth' have middle-class incomes and little cash on hand, making them react to income swings like the poor.
A new 5-qubit array demonstrates improved reliability in quantum computing, a crucial step towards building a functional quantum computer. The team's findings are based on theoretical work by Austin Fowler and the surface code architecture, which provides a way to control qubits properly.
A recent Mayo Clinic study discovered that individuals with mild cognitive impairment (MCI) tend to die at a higher rate than those without the condition. People with MCI experience an 80% increased risk of death over nearly six years.
Researchers discovered an enzyme pathway that safeguards against genome errors and cancer. Cdc14 activates Yen1 to repair breaks in DNA, helping to prevent devastating errors like chromosome loss.
Human-caused fires in the Primorsky Province of Russia are ravaging the landscape, with statistics showing that 94% of forest fires can be attributed to human activities. The uncontrolled burning of dry grass for centuries has led to widespread deforestation and degradation of forests, posing a significant threat to various species.
A study found that people reflected more on past events and developed a renewed interest in their online photos when a device called Photobox would randomly print four or five of those photos at varying intervals each month. This slower pace re-engage users with their own photos, making them a regular part of their everyday life.
A study by University of Toronto researchers found that male black widow spiders overwhelmingly choose well-fed, unmated females as mates. The preference is driven by pheromones released by females indicating their nutritional status.
A study published in Frontiers in Aging Neuroscience found that moderate physical activity can preserve the volume of the hippocampus in older adults at increased genetic risk for Alzheimer's disease. This suggests a potential delay in cognitive decline and onset of dementia symptoms.
Research found prenatal smoking and genetic risk factors increase aggressive behavior in children, particularly females, and that environmental experiences encompass more than just parenting.
Successful physics startups often differ from internet startups in terms of risk-taking and market strategies. Funding is a major challenge for entrepreneurs, with venture capitalists becoming more risk-averse.
A study found that aspirin lowers colorectal cancer risk in people with high 15-PGDH gene levels, but not those with low levels. The research team analyzed data from nearly 128,000 participants and discovered a link between 15-PGDH and the anti-cancer effects of aspirin.
Rates of PTSD increased sevenfold and severe distress nearly tripled over six years, with persisting injustice linked to a quadrupling of risk for PTSD. Mental health services should be enhanced to meet increased needs in post-conflict settings.
Scientists at Michigan State University have made a groundbreaking discovery that challenges long-standing theories on the origin of massive lava flows in Africa. The study found that some of these lavas came from within the African tectonic plate itself, rather than deep within the mantle.
Researchers found that triclosan and octylphenol promote breast cancer cell growth and tumor development in lab tests. The study's findings suggest that exposure to these endocrine-disrupting chemicals may significantly increase the risk of breast cancer development.
Researchers found that protein aggregates in Huntington's disease are not toxic, but rather a defense mechanism for stressed brain cells. This discovery may lead to new therapeutic approaches by targeting the stress response instead of protein clusters.
A study by Spanish researchers suggests that women's intuition is related to lower prenatal exposure to testosterone, leading to a more intuitive and less reflective mindset. This effect is stronger among women, who tend to give more intuitive answers in cognitive tests.
Researchers found functional electrical stimulation can promote endogenous neural precursor cell proliferation and improve motor function in rats with acute cerebral infarction. The treatment also enhanced expression of basic fibroblast growth factor and epidermal growth factor.
A new study found that genetic influence on body weight increases from 43% at age 4 to 82% at age 10, with environmental factors playing a lesser role. The research used twin and genomic analyses to demonstrate the rising association with BMI.
The proposed guidelines focus on study design, gene-variant implication, and database implications, emphasizing the need for detailed statistical analysis and evidence-based claims. Researchers highlight the importance of sharing genetic and clinical data to accelerate research and infrastructure development.
Researchers fabricate hemihelix shapes from flat parts using rubber strips and discover a critical aspect ratio for their formation. This phenomenon may lead to creation of new molecules with unusual properties.
Researchers at Vienna University of Technology have successfully controlled the splitting of hydrocarbons into smaller fragments using femtosecond laser pulses. By manipulating the distribution of electrons, scientists can induce chemical reactions and select specific reaction paths.
A study by Johns Hopkins Medicine found that rats exposed to high-energy particles simulating space radiation show lapses in attention and slower reaction times. The cognitive impairments are linked to protein changes in the brain and may be predicted by developing a biological marker for sensitivity to radiation's effects.
A new study by Lars Fändriks and Herbert Helander reveals the inner surface area of the gastro-intestinal tract in healthy adults is between 30-40 square meters. This is significantly smaller than previous estimates, which ranged from 180 to 300 square meters.
Scientists discovered over 400 genetic mutations in the white blood cells of a 115-year-old woman, indicating that these mutations may not contribute to disease. The study also found extremely short telomeres in the blood cells, suggesting 'stem cell exhaustion' as a possible cause of death at extreme ages.
A novel compound, RO5263397, has been found to severely blunt a range of cocaine addiction behaviors, including relapse behavior, in animal studies. The compound targets TAAR1 receptor and shows promise as a potential lead compound for treating cocaine addiction.
Researchers found the bio-duck sound is made by Antarctic minke whales, which stay in ice-covered waters year-round or migrate to lower latitudes. The discovery helps improve understanding of the species' distribution, abundance, and behavior.
A new analysis of NASA satellite data reveals a gradual decrease in Congo rainforest greenness, suggesting a slow adjustment to long-term drying trend. The study found that climate factors such as land surface temperatures and decreased cloudiness contribute to the observed browning of the forest canopy.
Researchers find prion protein attaches to amyloid-beta peptides, contrary to previous studies, and do not break them down into smaller pieces. This discovery bodes well for a potential approach using prion-protein-based compounds to treat Alzheimer's disease.
A UH biomedical engineer is working on a device to separate well-preserved red blood cells from potentially harmful materials in blood transfusions. The system uses microfluidic technology to scale up the separation process, making it safer and more efficient.
A study by Children's Hospital Los Angeles found strong correlations between seasonal ambient air pollutants and pregnancy loss in Ulaanbaatar, Mongolia. The researchers discovered a striking seasonal pattern of variation in miscarriage incidence, with increases in December due to increased hours of darkness and coldest temperatures.
Researchers found a strong correlation between shark abundance observed by citizen scientists and those identified by telemetry, suggesting that citizen science can be a cost-effective means to monitor shark populations. The study also showed that shark behavior was unaffected by tourist divers' presence.
A study published in the American Academy of Neurology found that individuals with higher levels of education tend to recover better from traumatic brain injuries. This is attributed to the cognitive reserve theory, which suggests that educated individuals have a greater ability to maintain brain function despite damage.
Researchers have discovered that chlorine atoms replace tellurium atoms within grain boundaries, creating local electric fields that boost photovoltaic performance. This finding could guide engineering of higher-efficiency CdTe solar cells.
Researchers at WSU have developed a scale to measure spitefulness, a behavior that involves hurting an opponent even when it comes at a cost to oneself. The study found that spitefulness is closely linked to other negative traits such as psychopathy and narcissism, and that people with guilt tend to score lower on the scale.
Researchers discovered that Pseudomonas aeruginosa bacteria use combinatorial communication to achieve an effect different from the sum of individual signals, a method previously thought to be unique to humans and some primates. This finding has serious implications for our understanding of language origins.
Researchers at Virginia Tech developed a novel method to detect the subcellular location of proteins, which will enable improved patient monitoring and drug development. The technique allows for rapid screening of large cell populations with high resolution, revealing heterogeneity among cells.
A new study from Indiana University School of Public Health-Bloomington found a strong association between heme iron consumption and coronary heart disease. Heme iron intake was shown to increase the risk for coronary heart disease by 57 percent, while nonheme iron had no such link.
Researchers at Harvard's SEAS discovered a hemihelix shape, rarely seen in nature, by stretching and joining rubber strips. The shape has a predictable and deterministic growth from a two-dimensional state to a three-dimensional state.
A new study at Rhode Island Hospital compared data from states with and without medical marijuana laws, finding no significant increase in adolescent marijuana use. The research suggests that state medical marijuana policies do not have a downstream effect on teenage drug use, contrary to concerns from the public.
A recent study finds that older mothers are at higher risk of having a child with an autism spectrum disorder (ASD), particularly when combined with intellectual disability. The risk is lower for fathers, who experience a more gradual increase in ASD risk as their age advances.
A study published in JAMA found that conservative management of brain arteriovenous malformations (abnormal connections between arteries and veins) was associated with lower rates of stroke and death compared to interventional treatment. The study followed 204 patients for up to 12 years, finding a significant reduction in nonfatal str...
A new prediction tool can help doctors identify patients at highest risk for respiratory failure after surgery, allowing them to take measures to prevent the condition. The tool uses nine predictors to determine a patient's risk level, enabling doctors to assign risk levels and use preventive measures more effectively.
Recent Minnesota projects demonstrate how communities can protect themselves from worsening storms through practical and affordable plans. The programs show that portions of existing drainage systems are already undersized, but significant portions should be adequate for even pessimistic mid-21st century projections.
A new study by Yale University and UC Davis researchers found that hysteroscopic sterilization is more than 10 times more likely to result in pregnancy over a 10-year period compared to laparoscopic sterilization. The study highlights the need for informed decision-making among women considering sterilization.
Researchers at the University of Toronto found a strong link between rapid-eye-movement sleep behavior disorder and neurodegenerative brain diseases. Up to 90% of people with RBD will develop a brain disease, making it an important warning sign for clinicians.
Researchers at VCU Massey Cancer Center have identified a critical protein called Noxa, which helps regulate the function of MCL-1 and makes cancer cells more sensitive to ABT-737. This breakthrough may lead to improved therapies for small cell lung cancer, overcoming resistance to conventional chemotherapies.
Researchers at Plymouth University will use drug and gene therapies to test whether altering mitochondrial fission or fusion improves dopamine-producing nerve cells in experimental models of Parkinson's Disease. The goal is to identify a potential new therapeutic strategy for this brain disorder, potentially slowing disease progress an...
The EORTC and SIOG have updated their expert opinion on NSCLC management in elderly patients, highlighting the need for personalized treatment decisions based on life expectancy and biological age. Multidisciplinary geriatric assessments can improve treatment outcomes for this population.
Researchers found that Cooperative Extension is a vital hub for community development efforts, providing resources and services to underserved communities. By partnering with local organizations and experts, Extension aims to address specific concerns and empower residents to influence their neighborhoods.
A study published in Psychological Science suggests that speed-reading apps, which eliminate eye movements, can impair reading comprehension. The researchers found that readers who are unable to make 'regressions' during reading have impaired comprehension levels.
Researchers have engineered a series of molecules with the potential to treat most neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's. The GAIM-changing molecules recognize characteristic common to many toxic misfolded proteins and can prevent new aggregates from forming while clearing existing ones.
A Cornell study published in Eating Behaviors found that children aged 6-10 who ate whole foods like drumsticks and apples were twice as likely to disobey adults and exhibit aggressive behavior compared to those eating cut-up foods. The researchers suggest cutting food can help reduce rowdy behavior at mealtime.