The Olig family is involved in regulating neural cell differentiation and affects acute and chronic central nervous system diseases. It also participates in the development of oligodendrocytes, motor neurons, and astrocytes in the central nervous system.
Researchers analyzed proteins in rat brains after giving them hallucinogenic drugs, finding 352 proteins that respond to the drug and cause changes in behavior. These protein changes may be comparable to those in a schizophrenic brain, paving the way for new treatments.
Research by the American Psychological Association found that people are more likely to register as organ donors if they have positive attitudes specifically about registering, rather than just supporting the idea of organ donation. Attitudes measured in surveys were key predictors of behavior.
The American College of Physicians has launched a High Value Care Coordination Toolkit to improve communication between primary care doctors and gastroenterologists. The toolkit includes data sets and guidelines for referrals, aiming to reduce unnecessary tests and delays in care.
Researchers have gained new understanding of how brain cells are formed and controlled by a key molecule miR-9, which is linked to brain development and function. This study could help explain what happens when cell production goes out of control in diseases like cancer.
A new trial involving sofosbuvir demonstrated promising results for patients with recurring HCV post-liver transplant, achieving SVR12 in 62% of cases. Additionally, improvements in clinical conditions associated with hepatic decompensation and liver function tests were observed.
A team of researchers has discovered a network of protein interactions among autism genes, shedding light on how different variants of the same protein could alter the wiring of the entire system. The study highlights the importance of considering alternative splice forms in understanding autism genetics.
A team of researchers from ASU will lead a multi-university project to understand the safety of nanomaterials throughout their life cycles. The project aims to develop molecular-level fundamental theories and provide databases of measurements to ensure manufacturing processes are safer.
A study published in Cell Death & Disease found that an overabundance of c-FLIPR protein disrupts the immune system's balance. Researchers discovered that this imbalance leads to autoantibodies attacking the body's own tissues, resulting in autoimmune diseases like systemic lupus erythematosus.
UAlberta researchers found that activating both AMPK and retrograde response pathways simultaneously can benefit cells with damaged mitochondria. This study provides a new concept for dealing with metabolic problems associated with mitochondrial disorders.
Researchers have developed robust new liver and fat cell models that report circadian clock function, allowing for high-throughput drug screening to find promising small molecules to resynchronize or help body clocks function normally.
A graduate student at UC Berkeley is using a new technique to recreate the appearance of ancient plants, shedding light on their evolution. The study, led by Jeff Benca, uses fossil fragments to create lifelike images of extinct plant species, including Leclercqia scolopendra, a centipede clubmoss from the Devonian Period.
A new research from the University of Southampton has identified a coral-eating flatworm as a potential threat to coral reefs. The researchers found that the small flatworm could cause significant damage to coral reefs due to its ability to mimic the appearance of its hosts.
The UTSA Center for Infrastructure Assurance and Security, along with partners, will develop a new training course and update five existing courses to enhance state preparedness for cyber attacks. The consortium aims to improve coordination among states in preventing, detecting, and responding to cyber threats.
The OU History of Science Department has received a $350,000 grant from the Alfred P. Sloan Foundation to build an innovative collaboration platform centered on the Isis Bibliography. The platform will make the entire bibliography available at no cost and provide users with digital tools for managing research and sharing work.
The study found that average waiting times for Nobel prizes are increasing exponentially, with average age at which laureates receive the award also rising. This trend threatens to undermine the prestigious award, as the predicted average age among prizewinners could even exceed life expectancy by the end of this century.
A team of AWI climate scientists deciphered a climate paradox from the Miocene era by analyzing complex model simulations. The expansion of the Antarctic ice sheet led to changes in wind patterns, ocean currents, and sea ice in the Southern Ocean, resulting in warming regions despite cooling elsewhere.
Researchers at UCSB created a compound semiconductor with embedded nanostructures that can manipulate light energy in the mid-infrared range. The technology has potential applications in solar cells, medical applications and plasmonics.
Researchers developed a self-defending surface that releases hot foam to deter attackers, protecting cash boxes in ATMs. The film is made of plastic layers filled with chemicals that mix when damaged, producing a violent reaction.
Researchers have discovered an immunotherapeutic approach to treating liver cancer, utilizing isolated T-cell receptors that can recognize and eliminate liver cancer cells. This new treatment option holds promise for patients with limited treatment options, including those with advanced stage HCC.
A recent study found that mortality from viral hepatitis is significantly higher than from HIV/AIDS across EU countries. In 2010, there were nearly 90,000 deaths due to hepatitis C and nearly 31,000 deaths due to hepatitis B, compared to just over 8,000 deaths from HIV/AIDS.
Scientists at Karlsruhe Institute of Technology have developed a chemical crosslinking reaction that ensures good short-term healing properties of the material under mild heating. The self-healing mechanism can be initiated by heat, light or chemical substance.
Researchers found evidence of the U.S. Clean Air Act in Greenland ice cores, showing a link between air acidity and nitrogen preservation. The study suggests that the relationship between emissions and isotopes is less direct than thought, with sulfur and nitrogen emissions contributing to the final signal recorded in the ice cores.
A Loyola University Medical Center study found that young athletes from higher-income families are 68% more likely to experience serious overuse injuries than those from lower-income families. The study also revealed that privately insured young athletes are twice as likely to specialize in one sport, increasing their risk of injury.
A new facial selection technique can enhance ad effectiveness by 15% and generate $5 billion in additional US automotive sales, researchers say. The method automates the subjective process of selecting faces for ads.
A study by Women's College Hospital found women with diabetes are 14% less likely to get mammograms, despite higher breast cancer risk. Low socioeconomic status exacerbates this disparity.
Researchers have discovered that the bicolored shrew acts as a 'pathogen reservoir' for the Borna virus, transmitting it to horses. The virus is not directly contagious and requires an intermediate host to spread, highlighting the importance of keeping shrews away from stables to prevent transmission.
A new study by McGill University professor Shaun Lovejoy uses statistical analysis to determine the probability that global warming since 1880 is due to natural variability. The study concludes that the natural-warming hypothesis can be ruled out with confidence levels greater than 99%, and most likely greater than 99.9%.
The Lancet Oncology publishes a major new Commission examining the challenges to effective cancer control in China, India, and Russia. The report highlights disparities in access to cancer care, poor quality of data collection, and barriers to improving cancer care related to social, economic, and environmental factors.