Researchers discovered that commonly used NSAIDs alter the activity of enzymes within cell membranes, which can lead to unwanted side effects. This finding provides a basis for a test to predict and avoid these side effects in new medicines.
A new study from USC Eye Institute reveals that Native American ancestry is a significant risk factor for vision-threatening diabetic retinopathy among Latinos with Type 2 diabetes. The research found individuals with more than 50% Native American ancestry had an 87% higher chance of developing severe diabetic retinopathy.
Scientists found that sunlight, not bacteria, dominates the production of carbon dioxide in Arctic inland waters. Photochemical processing accounts for up to 95% of carbon conversion.
Scientists at UC San Diego's Scripps Institution used GPS technology to track uplift caused by the severe drought, estimating a water deficit of 62 trillion gallons. This has resulted in an average uplift of 4 millimeters across the western US and up to 15 millimeters in California's mountains.
Researchers found that Deformed Wing Virus (DWV) is the most affected virus species by Varroa infestation, while Kashmir Bee Virus (KBV) peaks two years after initial infestation and disappears. The study highlights the importance of beekeeper awareness, mite monitoring, and efficient Varroa control.
A team of researchers, including a UC Riverside assistant professor, developed a method to attack apps on Android and other operating systems with high success rates. They tested the method on six popular apps, including Gmail, and found it was successful between 82-92% of the time.
A new study by University of Toronto researchers explores the relationship between Islam and liberal democracy in Muslim-majority countries. They found that while people in these countries are less tolerant on average than those in Western nations, socio-economic conditions and political regimes play a significant role.
Scientists discovered a new subgroup of cyanobacteria that can absorb and use far-red light for photosynthesis, replacing 17 proteins in three major complexes. This process has a dramatic effect on the organism's physiology and metabolism, producing 40% more oxygen.
The NSF awards two $10 million projects to create cloud computing testbeds, enabling the academic research community to develop and experiment with novel cloud architectures. Chameleon and CloudLab will support real-time and safety-critical applications in medical devices, power grids, and transportation systems.
A UCLA study suggests that excessive digital media use is linked to declining social skills in children, as they spend less time engaging in face-to-face interactions. The research found that sixth-graders who went device-free for five days showed significant improvements in recognizing human emotions compared to their peers.
Researchers at JILA have confirmed the presence of spin symmetry in strontium atoms, which could lead to breakthroughs in simulating exotic materials and understanding quantum phenomena like superconductivity. The discovery was made possible by an ultra-stable atomic clock, allowing for precise measurements of atom interactions.
Research suggests that climate change could lead to an increased risk of dengue fever in Europe, particularly in coastal areas along the Mediterranean and Adriatic seas. The disease is spread by mosquitoes, which thrive in warm and humid conditions, making these regions most at risk.
Researchers at University of Washington found that heat absent from Earth's surface is plunging deep into the North and South Atlantic Ocean, part of a naturally occurring cycle. This explains the global average air temperature flatlining since 1999 despite greenhouse gases.
Researchers funded by NSF publish paper confirming presence of viable microbial ecosystems in subglacial Lake Whillans, 800 meters beneath the West Antarctic ice sheet. The discovery has implications for life in other extreme environments and may influence the chemical and biological composition of the Southern Ocean.
Researchers at the University of Montreal found that sleep improves performance on piano tasks by increasing communication between subcortical brain regions. After a night of sleep, these regions function with greater synchrony, enabling better motor learning and memory consolidation.
Researchers at Princeton University developed a laser-based method to measure blood sugar levels without needing frequent pricking. The technique uses mid-infrared light and is currently 84% accurate, with potential applications beyond glucose detection.
Despite their crucial position, primary care physicians in rural communities rarely screen women for intimate partner violence (IPV). Women experiencing IPV in these areas often face limited resources and support. Providing training to PCPs, educating the community, and improving access to referral services can help address this issue.
Yale physicists have successfully cooled strontium monofluoride to near absolute zero using magneto-optical trapping, enabling new research in quantum chemistry and particle physics. The discovery opens doors for experimentation in precision measurement, quantum simulation, ultracold chemistry, and tests of the standard model.
Patients with advanced laryngeal cancer who underwent surgery had significantly better disease-specific and overall survival rates compared to those treated with nonsurgical chemoradiation. The study analyzed data from over 5,000 patients diagnosed between 1992 and 2009.
A new study shows that the Greater Toronto Area has reduced some smog precursors by at least 20% since 2004, but still exceeds Canada's ozone standards due to high sunshine and calm winds. The research found that lower ozone levels between 2008 and 2011 were offset by a record-high summer ozone concentration in 2012.
Researchers at Georgia State University found that humans are strongly influenced by self-interest and do not protest being overcompensated, even in situations where others are unfairly disadvantaged. This suggests that humans' sense of unfairness is affected by their own outcomes, indicating a recently evolved propensity.
Young corals and fish are repelled by the smell of damaged reefs, discouraging them from settling in degraded habitats. Marine protected areas may not be sufficient to promote reef recovery as chemical cues continue to drive away new fish and coral long after overfishing has stopped.
A novel decision support system combines computer vision algorithms with visualization of relevant areas to aid in malaria diagnosis. The method was shown to be accurate comparable to World Health Organization quality criteria, with over 90% of infected samples correctly diagnosed.
Researchers successfully characterized quantum vortices in helium nanodroplets for the first time, revealing unique features and opening new avenues to study quantum rotation. The discovery confirms that helium nanodroplets are superfluid throughout and exhibit a single quantum object behavior.
MIT researchers have created an algorithm that enables a drone to monitor its health in real-time, allowing it to take proactive measures during delivery missions. The approach simplifies planning by separating vehicle-level and mission-level tasks, resulting in more efficient and reliable deliveries.
A new study by the Institute of Food Technologists found that okra extracts can be used as a stabilizer in ice cream, improving texture and extending shelf life. The naturally extracted stabilizers offer an alternative to traditional stabilizers, making them suitable for the ice cream industry.
Overexpression of Notch1 in temporal lobe epilepsy is associated with reduced seizure frequency and brain discharges. The study found increased presence of Notch 1 and hairy and enhancer of split-1 in intractable temporal lobe epilepsy patients, suggesting potential therapeutic targets for treating the condition.
A new study finds that sunlight, not bacteria, is the key to converting carbon stored in Arctic permafrost into carbon dioxide. As climate change alters the timing and pace of thawing, this process could significantly impact global CO2 levels.
Researchers found MSCs in patient's blood after severe trauma, suggesting they are released from bone marrow into bloodstream following organ damage. The study provides conclusive evidence for the mobilization and migration of MSCs in humans.
Researchers at Berkeley Lab have observed the direct formation of facets on platinum nanocubes, revealing that a long-held scientific principle breaks down at the nanoscale. This breakthrough enables the control of a nanocrystal's geometric shape and its subsequent chemical and electronic properties.
Researchers at the University of Surrey have discovered a new mechanism for controlling bladder contractions and regulating the body's clock genes. This finding has implications for understanding the pathology and development of new treatments for overactive bladder and irritable bowel syndrome.
Researchers discovered how hummingbirds detected sugar by analyzing their taste receptors, which expanded to respond to carbohydrates. The study revealed that a single mutation drove behavior changes in the birds.
A new study found that orgasm rates for single women vary by sexual orientation, with lesbian women experiencing the highest rate. The study analyzed data from over 2,800 individuals and suggests that partner communication and biological factors may contribute to these variations.
Tropical Storm Karina appeared as a giant number nine due to strong thunderstorms spiraling into its center. The storm is now weakening due to moderate-to-strong vertical wind shear and dry air affecting its development of thunderstorms.
A study by researchers at the University of Kansas reveals a new function for APC in protecting against chronic colitis-induced inflammation and tumor development. The team found that functional nuclear APC is necessary to suppress Wnt signaling pathway, controlling goblet cell differentiation.
A new study by Brigham Young University researchers suggests that gamification in health and fitness apps may not lead to sustainable behavior change. The study analyzed over 2,000 apps and found that most popular apps feature gamification as a key motivator, but this approach may be limited and demotivating in the long run.
Research reveals that men who objectify their partner's bodies experience increased shame, leading to higher rates of sexual pressure and coercion. Women internalize objectification, affecting communication, respect, and relationship satisfaction.
A team of scientists sequenced chromophobe renal cell carcinoma tumors and found unique alterations involving telomerase, a gene that plays a critical role in cell division. This discovery provides new clues about the disease's biology and may lead to the development of targeted therapies for this rare type of kidney cancer.
The American College of Chest Physicians has released a consensus statement providing evidence-informed suggestions for preparing and managing the critically ill and injured during large-scale disasters and pandemics. The document aims to guide ethical decision-making, coordination of care, resource conservation, and research in crises.
Scientists have isolated a mutated polio virus that can evade the immune system and render vaccinations ineffective. This discovery is alarming as it threatens to undermine progress made in eradicating polio, which has been nearly eradicated thanks to effective vaccination.
Researchers found that viruses infecting algae drive the life-and-death dynamics of massive algal blooms, with a single bloom fixing about as much carbon as an equivalent patch of rainforest. This has significant implications for climate and ocean carbon sequestration.
A new study finds that calcium buildup in coronary arteries is a strong indicator of heart disease risk in individuals with chronic kidney disease. This measure outperforms other commonly used tests in predicting cardiovascular disease among CKD patients, who are at high risk for heart disease.
Researchers found that TeleStroke Units improved stroke care in rural Bavaria, Germany, by increasing the number of patients receiving tissue plasminogen activator (tPA) from 2.6% to 15.5%. The median time between arrival and tPA administration fell from 80 minutes to 40 minutes.
A study published in The Journal of Nutrition found that a blood sample can be used to assess dietary compliance. The researchers identified biomarkers in the blood that reflected consumption of key components of a healthy Nordic diet, including fatty fish, vegetables, and whole grains.
Despite government promises, satellite analysis shows no significant increase in civic facilities in Sri Lanka's Valikamam High-Security Zone. The area has seen a sharp increase in residential housing-type structures and development.
A new DNA test can identify the exact genetic cause of congenital cataracts in 75% of cases, allowing for earlier treatment and genetic counseling. The targeted next-generation sequencing test has been shown to be effective in diagnosing rare diseases associated with childhood blindness.
A study by Lin Li et al. found that preconditioning crush reduces ventral motor neuron loss after nerve root avulsion. The authors propose a mechanism involving HSP27 induction, which attenuates cytotoxic effects of nitric oxide.
Researchers at Lund University found that toothpaste fluorine is formed in stars similar to our sun, supporting a theory about its origins. By analyzing light emitted by stars, they calculated the amount of fluorine present and compared it with predictions.
Researchers propose that high-energy particles from solar storms can create sparking, altering the moon's polar soil and potentially reactivating permanently shadowed regions. This 'breakdown weathering' process could change our understanding of planetary evolution in extremely cold regions.
Researchers use X-rays to explore helium nanodroplets, finding unprecedented quantities of quantum vortices that lead to extreme deformation and anomalous behavior. The study sheds light on the properties of superfluids at microscopic scales.
New research at Rockefeller University reveals how IELs develop to protect the intestinal epithelium, a critical interface between the gut and body. Understanding this pathway may lead to new insights into inflammatory diseases of the gut and cancer.
Researchers at the NIH have developed a new animal model of severe Middle East respiratory syndrome coronavirus (MERS-CoV) infection in marmosets. This model closely mimics the severe pneumonia experienced by people infected with MERS-CoV, making it an ideal option for testing potential treatments.
Researchers found that girls with vulvitis were eight times more likely to have a lab-diagnosed UTI than those without vulvitis. Vulvitis may cause UTIs by altering the type of bacteria normally found in the area between the vagina and anus.
A study found that children with autism have a surplus of synapses in the brain due to a slowdown in synaptic pruning during development. The researchers discovered that administering a drug called rapamycin can improve autistic-like behaviors in mice, even when given after the behaviors have appeared.
Researchers developed a technique that uses fluorescence lifetime measurements to automatically sort plastics, reducing contamination levels and increasing re-use efficiency. The new method can process up to 1.5 tons of plastic per hour, meeting industrial scale requirements.
Researchers found that calcium build-up in coronary artery walls is a more useful indicator of heart disease risk in patients with CKD than traditional measures of atherosclerosis. The study suggests that this finding could help safeguard the heart health of millions of people globally who have chronic kidney disease.
Researchers have developed a new method to create patient-specific neural crest cells from skin cells, which can help study and potentially treat rare disorders. The technique accelerates the creation of these cells, allowing for more accurate predictions of disease progression and treatment efficacy.
Researchers have discovered a well-organized 3-D grid of quantum tornadoes inside microscopic droplets of supercooled liquid helium. This formation provides proof of the droplets' quantum state and is different from the lone whirlpool that would form in a regular liquid.
ORNL scientists uncover clues to role of magnetism in iron-based superconductors, finding localized magnetism correlated with high critical temperature and influencing material performance. The study provides experimental evidence that local magnetic fluctuations can influence the behavior of iron-based superconductors.
A new study suggests that combining Salk inactivated poliovirus vaccine (IPV) with Sabin live-attenuated oral poliovirus vaccine (OPV) improves mucosal immunity and reduces viral shedding. The results could help resolve the long-standing debate over vaccine choice in areas where polio is difficult to eradicate.