Researchers analyzed 500 patients with diabetes mellitus and found altered nerve conduction in the early asymptomatic stage of diabetic peripheral neuropathy. The amplitude of sensory nerve action potential was the most sensitive measure of this condition, revealing varying degrees of nerve conduction changes.
Researchers found that geniposide, a component of the Chinese herbal formula Tongluojiunao, protects hippocampal neurons from Aβ1-mediated cell death via a non-classical estrogen signaling pathway. This study suggests a new potential therapeutic approach for Alzheimer's disease.
Hurricane Lowell strengthened into a Category One hurricane with sustained winds of 75 mph after being observed by NASA satellites. The storms' cloud top temperatures exceeded -63F, indicating high thunderstorms with potential heavy rainfall.
Scientists have developed a genetically engineered mouse line that allows them to study calcium levels in living brain cells, enabling new research on epilepsy, Alzheimer's, and other neurological diseases. This breakthrough opens up possibilities for new treatments and a deeper understanding of the immune system's role in brain function.
Researchers successfully constructed an adenovirus that induces DHCR24 specifically in neuronal cells, demonstrating its neuroprotective effects against amyloid beta-induced apoptosis. This breakthrough paves the way for further studies on DHCR24 gene therapy and neuronal functional research.
A new study found that overweight individuals with type 2 diabetes who lose weight through dieting and physical activity can reduce their healthcare costs by an average of over $500 per year. Those in the intensive lifestyle intervention group had fewer hospitalizations, shorter hospital stays, and used fewer prescription medications.
The University of Wisconsin-Madison has been selected to participate in the National Science Foundation-funded CloudLab project, which aims to develop cloud infrastructure and support high-level research. The $2.3 million grant will enable researchers to evaluate novel cloud technologies in a realistic environment.
A newly discovered species of ant, Mycocepurus castrator, has been found to support the theory of sympatric speciation, where a new species develops within a single colony. The research team found that the parasitic ants were genetically close to their host, but no longer reproductively compatible and had stopped reproducing together 3...
Researchers found that elasticity, free oil, moisture, water activity, and transition temperature influence color uniformity of cheeses. Mozzarella can be combined with less burnt cheeses like Gruyere or provolone to create a gourmet pizza.
Researchers found that negative emotions like anger can be used as a force for good when motivated by moral standards, while excessive positivity can lead to complacency and superficiality. In some team situations, negativity can actually enhance discussion and effectiveness.
Reconstruction of sea ice changes in the Fram Strait reveals that Arctic sea ice cover decline led to significant weakening of the Gulf Stream. This change had a direct impact on European climate, with cooling occurring twice in the past 30,000 years.
Researchers detected quantum vortices in nanodroplets of liquid helium, forming a densely packed lattice. The droplets rotated at up to 14 million times per second, defying classical physics.
A Canadian team outlines possible coping mechanisms for lost or stolen mobile devices, highlighting the importance of user awareness and organization security measures. The researchers found that many users are either unaware or unwilling to use security countermeasures, leaving them vulnerable to data loss risks.
Researchers develop theoretical framework to generate coherent radiations in the water window range, enabling high-contrast imaging of biological samples. The study extends previous work on hydrogen and applies it to argon atoms, paving the way for improved spectroscopy techniques.
Using Extracorporeal Membrane Oxygenation (ECMO) has increased the number of organs available for transplant after circulatory death by 20%. This technology improves organ viability, particularly for kidneys, livers, and pancreases, making more life-saving organs available for patients waiting for transplants.
A new study projects a continued decline in US edentulism prevalence through 2050, with high-income households experiencing the steepest reduction. However, tooth loss remains disproportionately prevalent among low-income populations, highlighting a need for targeted public health measures to address this issue.
A University of New Hampshire and NASA study suggests that high-energy particles from solar storms can charge the moon's polar soil, creating sparking and potentially altering its composition. This process could have significant implications for our understanding of planetary surfaces in extremely cold regions.
Researchers from Louisiana State University have confirmed the existence of microbial life in a subglacial lake beneath the West Antarctic ice sheet. The discovery sheds new light on the potential for life in other extreme environments and has implications for our understanding of the planet's biosphere.
Researchers discovered that commonly used NSAIDs alter the activity of enzymes within cell membranes, which can lead to unwanted side effects. This finding provides a basis for a test to predict and avoid these side effects in new medicines.
A new study from USC Eye Institute reveals that Native American ancestry is a significant risk factor for vision-threatening diabetic retinopathy among Latinos with Type 2 diabetes. The research found individuals with more than 50% Native American ancestry had an 87% higher chance of developing severe diabetic retinopathy.
Scientists found that sunlight, not bacteria, dominates the production of carbon dioxide in Arctic inland waters. Photochemical processing accounts for up to 95% of carbon conversion.
Scientists at UC San Diego's Scripps Institution used GPS technology to track uplift caused by the severe drought, estimating a water deficit of 62 trillion gallons. This has resulted in an average uplift of 4 millimeters across the western US and up to 15 millimeters in California's mountains.
Researchers found that Deformed Wing Virus (DWV) is the most affected virus species by Varroa infestation, while Kashmir Bee Virus (KBV) peaks two years after initial infestation and disappears. The study highlights the importance of beekeeper awareness, mite monitoring, and efficient Varroa control.
A team of researchers, including a UC Riverside assistant professor, developed a method to attack apps on Android and other operating systems with high success rates. They tested the method on six popular apps, including Gmail, and found it was successful between 82-92% of the time.
A new study by University of Toronto researchers explores the relationship between Islam and liberal democracy in Muslim-majority countries. They found that while people in these countries are less tolerant on average than those in Western nations, socio-economic conditions and political regimes play a significant role.
Scientists discovered a new subgroup of cyanobacteria that can absorb and use far-red light for photosynthesis, replacing 17 proteins in three major complexes. This process has a dramatic effect on the organism's physiology and metabolism, producing 40% more oxygen.
The NSF awards two $10 million projects to create cloud computing testbeds, enabling the academic research community to develop and experiment with novel cloud architectures. Chameleon and CloudLab will support real-time and safety-critical applications in medical devices, power grids, and transportation systems.
A UCLA study suggests that excessive digital media use is linked to declining social skills in children, as they spend less time engaging in face-to-face interactions. The research found that sixth-graders who went device-free for five days showed significant improvements in recognizing human emotions compared to their peers.
Researchers at JILA have confirmed the presence of spin symmetry in strontium atoms, which could lead to breakthroughs in simulating exotic materials and understanding quantum phenomena like superconductivity. The discovery was made possible by an ultra-stable atomic clock, allowing for precise measurements of atom interactions.
Research suggests that climate change could lead to an increased risk of dengue fever in Europe, particularly in coastal areas along the Mediterranean and Adriatic seas. The disease is spread by mosquitoes, which thrive in warm and humid conditions, making these regions most at risk.
Researchers at University of Washington found that heat absent from Earth's surface is plunging deep into the North and South Atlantic Ocean, part of a naturally occurring cycle. This explains the global average air temperature flatlining since 1999 despite greenhouse gases.
Researchers funded by NSF publish paper confirming presence of viable microbial ecosystems in subglacial Lake Whillans, 800 meters beneath the West Antarctic ice sheet. The discovery has implications for life in other extreme environments and may influence the chemical and biological composition of the Southern Ocean.
Researchers at the University of Montreal found that sleep improves performance on piano tasks by increasing communication between subcortical brain regions. After a night of sleep, these regions function with greater synchrony, enabling better motor learning and memory consolidation.
Researchers at Princeton University developed a laser-based method to measure blood sugar levels without needing frequent pricking. The technique uses mid-infrared light and is currently 84% accurate, with potential applications beyond glucose detection.
Despite their crucial position, primary care physicians in rural communities rarely screen women for intimate partner violence (IPV). Women experiencing IPV in these areas often face limited resources and support. Providing training to PCPs, educating the community, and improving access to referral services can help address this issue.
Yale physicists have successfully cooled strontium monofluoride to near absolute zero using magneto-optical trapping, enabling new research in quantum chemistry and particle physics. The discovery opens doors for experimentation in precision measurement, quantum simulation, ultracold chemistry, and tests of the standard model.
Patients with advanced laryngeal cancer who underwent surgery had significantly better disease-specific and overall survival rates compared to those treated with nonsurgical chemoradiation. The study analyzed data from over 5,000 patients diagnosed between 1992 and 2009.
A new study shows that the Greater Toronto Area has reduced some smog precursors by at least 20% since 2004, but still exceeds Canada's ozone standards due to high sunshine and calm winds. The research found that lower ozone levels between 2008 and 2011 were offset by a record-high summer ozone concentration in 2012.
Researchers at Georgia State University found that humans are strongly influenced by self-interest and do not protest being overcompensated, even in situations where others are unfairly disadvantaged. This suggests that humans' sense of unfairness is affected by their own outcomes, indicating a recently evolved propensity.
Young corals and fish are repelled by the smell of damaged reefs, discouraging them from settling in degraded habitats. Marine protected areas may not be sufficient to promote reef recovery as chemical cues continue to drive away new fish and coral long after overfishing has stopped.
A novel decision support system combines computer vision algorithms with visualization of relevant areas to aid in malaria diagnosis. The method was shown to be accurate comparable to World Health Organization quality criteria, with over 90% of infected samples correctly diagnosed.
Researchers successfully characterized quantum vortices in helium nanodroplets for the first time, revealing unique features and opening new avenues to study quantum rotation. The discovery confirms that helium nanodroplets are superfluid throughout and exhibit a single quantum object behavior.
MIT researchers have created an algorithm that enables a drone to monitor its health in real-time, allowing it to take proactive measures during delivery missions. The approach simplifies planning by separating vehicle-level and mission-level tasks, resulting in more efficient and reliable deliveries.
A new study by the Institute of Food Technologists found that okra extracts can be used as a stabilizer in ice cream, improving texture and extending shelf life. The naturally extracted stabilizers offer an alternative to traditional stabilizers, making them suitable for the ice cream industry.
Overexpression of Notch1 in temporal lobe epilepsy is associated with reduced seizure frequency and brain discharges. The study found increased presence of Notch 1 and hairy and enhancer of split-1 in intractable temporal lobe epilepsy patients, suggesting potential therapeutic targets for treating the condition.
A new study finds that sunlight, not bacteria, is the key to converting carbon stored in Arctic permafrost into carbon dioxide. As climate change alters the timing and pace of thawing, this process could significantly impact global CO2 levels.
Researchers found MSCs in patient's blood after severe trauma, suggesting they are released from bone marrow into bloodstream following organ damage. The study provides conclusive evidence for the mobilization and migration of MSCs in humans.
Researchers at Berkeley Lab have observed the direct formation of facets on platinum nanocubes, revealing that a long-held scientific principle breaks down at the nanoscale. This breakthrough enables the control of a nanocrystal's geometric shape and its subsequent chemical and electronic properties.
Researchers at the University of Surrey have discovered a new mechanism for controlling bladder contractions and regulating the body's clock genes. This finding has implications for understanding the pathology and development of new treatments for overactive bladder and irritable bowel syndrome.
Researchers discovered how hummingbirds detected sugar by analyzing their taste receptors, which expanded to respond to carbohydrates. The study revealed that a single mutation drove behavior changes in the birds.
A new study found that orgasm rates for single women vary by sexual orientation, with lesbian women experiencing the highest rate. The study analyzed data from over 2,800 individuals and suggests that partner communication and biological factors may contribute to these variations.
Tropical Storm Karina appeared as a giant number nine due to strong thunderstorms spiraling into its center. The storm is now weakening due to moderate-to-strong vertical wind shear and dry air affecting its development of thunderstorms.
A study by researchers at the University of Kansas reveals a new function for APC in protecting against chronic colitis-induced inflammation and tumor development. The team found that functional nuclear APC is necessary to suppress Wnt signaling pathway, controlling goblet cell differentiation.
A new study by Brigham Young University researchers suggests that gamification in health and fitness apps may not lead to sustainable behavior change. The study analyzed over 2,000 apps and found that most popular apps feature gamification as a key motivator, but this approach may be limited and demotivating in the long run.
Research reveals that men who objectify their partner's bodies experience increased shame, leading to higher rates of sexual pressure and coercion. Women internalize objectification, affecting communication, respect, and relationship satisfaction.
A team of scientists sequenced chromophobe renal cell carcinoma tumors and found unique alterations involving telomerase, a gene that plays a critical role in cell division. This discovery provides new clues about the disease's biology and may lead to the development of targeted therapies for this rare type of kidney cancer.
The American College of Chest Physicians has released a consensus statement providing evidence-informed suggestions for preparing and managing the critically ill and injured during large-scale disasters and pandemics. The document aims to guide ethical decision-making, coordination of care, resource conservation, and research in crises.
Scientists have isolated a mutated polio virus that can evade the immune system and render vaccinations ineffective. This discovery is alarming as it threatens to undermine progress made in eradicating polio, which has been nearly eradicated thanks to effective vaccination.
Researchers found that viruses infecting algae drive the life-and-death dynamics of massive algal blooms, with a single bloom fixing about as much carbon as an equivalent patch of rainforest. This has significant implications for climate and ocean carbon sequestration.
A new study finds that calcium buildup in coronary arteries is a strong indicator of heart disease risk in individuals with chronic kidney disease. This measure outperforms other commonly used tests in predicting cardiovascular disease among CKD patients, who are at high risk for heart disease.
Researchers found that TeleStroke Units improved stroke care in rural Bavaria, Germany, by increasing the number of patients receiving tissue plasminogen activator (tPA) from 2.6% to 15.5%. The median time between arrival and tPA administration fell from 80 minutes to 40 minutes.
A study published in The Journal of Nutrition found that a blood sample can be used to assess dietary compliance. The researchers identified biomarkers in the blood that reflected consumption of key components of a healthy Nordic diet, including fatty fish, vegetables, and whole grains.
Despite government promises, satellite analysis shows no significant increase in civic facilities in Sri Lanka's Valikamam High-Security Zone. The area has seen a sharp increase in residential housing-type structures and development.
A new DNA test can identify the exact genetic cause of congenital cataracts in 75% of cases, allowing for earlier treatment and genetic counseling. The targeted next-generation sequencing test has been shown to be effective in diagnosing rare diseases associated with childhood blindness.
A study by Lin Li et al. found that preconditioning crush reduces ventral motor neuron loss after nerve root avulsion. The authors propose a mechanism involving HSP27 induction, which attenuates cytotoxic effects of nitric oxide.
Researchers at Lund University found that toothpaste fluorine is formed in stars similar to our sun, supporting a theory about its origins. By analyzing light emitted by stars, they calculated the amount of fluorine present and compared it with predictions.
Researchers propose that high-energy particles from solar storms can create sparking, altering the moon's polar soil and potentially reactivating permanently shadowed regions. This 'breakdown weathering' process could change our understanding of planetary evolution in extremely cold regions.
Researchers use X-rays to explore helium nanodroplets, finding unprecedented quantities of quantum vortices that lead to extreme deformation and anomalous behavior. The study sheds light on the properties of superfluids at microscopic scales.
New research at Rockefeller University reveals how IELs develop to protect the intestinal epithelium, a critical interface between the gut and body. Understanding this pathway may lead to new insights into inflammatory diseases of the gut and cancer.
Researchers at the NIH have developed a new animal model of severe Middle East respiratory syndrome coronavirus (MERS-CoV) infection in marmosets. This model closely mimics the severe pneumonia experienced by people infected with MERS-CoV, making it an ideal option for testing potential treatments.
Researchers found that girls with vulvitis were eight times more likely to have a lab-diagnosed UTI than those without vulvitis. Vulvitis may cause UTIs by altering the type of bacteria normally found in the area between the vagina and anus.
A study found that children with autism have a surplus of synapses in the brain due to a slowdown in synaptic pruning during development. The researchers discovered that administering a drug called rapamycin can improve autistic-like behaviors in mice, even when given after the behaviors have appeared.
Researchers developed a technique that uses fluorescence lifetime measurements to automatically sort plastics, reducing contamination levels and increasing re-use efficiency. The new method can process up to 1.5 tons of plastic per hour, meeting industrial scale requirements.
Researchers found that calcium build-up in coronary artery walls is a more useful indicator of heart disease risk in patients with CKD than traditional measures of atherosclerosis. The study suggests that this finding could help safeguard the heart health of millions of people globally who have chronic kidney disease.
Researchers have developed a new method to create patient-specific neural crest cells from skin cells, which can help study and potentially treat rare disorders. The technique accelerates the creation of these cells, allowing for more accurate predictions of disease progression and treatment efficacy.
Researchers have discovered a well-organized 3-D grid of quantum tornadoes inside microscopic droplets of supercooled liquid helium. This formation provides proof of the droplets' quantum state and is different from the lone whirlpool that would form in a regular liquid.
ORNL scientists uncover clues to role of magnetism in iron-based superconductors, finding localized magnetism correlated with high critical temperature and influencing material performance. The study provides experimental evidence that local magnetic fluctuations can influence the behavior of iron-based superconductors.
A new study suggests that combining Salk inactivated poliovirus vaccine (IPV) with Sabin live-attenuated oral poliovirus vaccine (OPV) improves mucosal immunity and reduces viral shedding. The results could help resolve the long-standing debate over vaccine choice in areas where polio is difficult to eradicate.
Researchers at Duke University have identified three tree species as environmental hosts for the fungus Cryptococcus gattii, which causes life-threatening lung and brain infections. The study found that these tree species can serve as sources of human infections, particularly for individuals with compromised immune systems.
Research from San Francisco State University finds that individuals with schizophrenia struggle to set high-effort goals due to difficulty assessing effort required. Breaking down tasks into smaller ones with small rewards can help patients function normally and counter motivation deficits.
Malassezia fungi, linked to human skin conditions, have been found across multiple environments including Hawaiian coral reefs, arctic soils, and deep sea vents. They dominate certain marine ecosystems and are also found in marine mammals and fish, suggesting a broader ecological significance.
Researchers at University of Waterloo are investigating factors impacting food intake in long-term care settings, with a focus on improving nutrition for older adults. The study, funded by $1.5 million in grants, aims to understand the complex relationships between meal quality, food access, and mealtime experience.
The Lancet emphasizes the need for fair distribution of experimental Ebola drugs and rigorous testing in clinical trials. Bioethicists recommend prioritizing containment of the epidemic and strengthening health systems over treatment with potentially ineffective interventions.
Researchers found that green tea polyphenols effectively protect spinal cord neurons against hydrogen peroxide-induced oxidative stress. The study published in Neural Regeneration Research revealed that green tea polyphenols inhibit neuronal apoptosis, indicating a protective role in spinal cord neurons under oxidative stress.
Researchers found that ADHD children use less differentiated learning patterns, leading to suboptimal decisions. The study used mathematical models and multimodal imaging to examine brain activity in participants with and without ADHD.
A new study found that mindfulness-based cognitive therapy significantly reduced non-mental health care visits among patients who were high health service users. Over eight years, this translates to a reduction of nearly 2,500 visits to primary care physicians, emergency departments, or non-psychiatric specialists in Ontario.
A novel modeling strategy simulates polyelectrolyte systems, enabling the prediction of desirable characteristics for various applications. The 'implicit solvent ionic strength method' reduces computational costs, allowing for quicker results and larger system complexity.
The University of Houston is launching a new center to increase female STEM faculty recruitment, particularly among women of color. The five-year grant will support workshops on inclusion and diversity, mentorship programs, and senior administrative fellowships for women in STEM leadership roles.
The completed Canola genome sequence sheds light on its complex evolutionary history with Brassica rapa and Brassica oleracea. Researchers aim to use this knowledge to improve canola traits such as flowering time, disease resistance and nutritional content.
A study by the JAMA Network found that vision loss significantly impacts daily life and can increase mortality risk. The research highlights the importance of addressing vision impairment to prevent adverse outcomes.
A new species of carnivorous crustacean, Thylacares brandonesis, has been identified from a 435 million-year-old fossil found in Wisconsin. The creature used long, claw-like appendages to catch prey, similar to modern remipedes.
Researchers identified a key clue to treating absence seizures by deleting the T-type calcium channel CaV3.3 in mice, which suppressed burst firing and increased tonic firing. This study challenges existing hypotheses and provides a foundation for developing effective treatment methods.
A study published by Kessler Foundation found small but significant differences in self-care and mobility at discharge among patients with motor complete spinal cord injury (SCI), with non-Hispanic blacks showing less improvement compared to Hispanics and non-Hispanic whites. The study used data from the Spinal Cord Injury Model System...
Acute pancreatitis is a severe condition where the pancreas digests itself, leading to abdominal pain, vomiting, and systemic inflammation. Recent research suggests that insulin may prevent toxic effects of alcohol and fatty acid metabolites on pancreatic acinar cells.
Researchers have identified marmosets as an ideal animal model to study Middle East respiratory syndrome corona virus (MERS-CoV) due to their DPP4 protein's similarity to humans. The marmoset model recapitulates severe respiratory symptoms seen in human patients, making it a promising candidate for future therapeutic studies.
Arctic sea ice covered about 2.31 million square miles on Aug. 19, falling short of the record low in 2012 but continuing a trend of decline over the past 30 years. NASA scientists are flying three airborne research campaigns to study climate-driven changes in the Arctic.
Research found a strong association between low birth weight and type 2 diabetes in African American women, with those born very low weight facing a 40% increased risk. The study's findings shed light on the long-term health effects of low birth weight in this population.