Researchers found that methylation patterns in acute myeloid leukemia patient samples were prognostic for overall survival. A novel biomarker for lysosomal storage disorders was also identified by correlating relative acidic compartment volumes with clinical severity.
Researchers found amino acids and biologically important molecules in carbon-rich meteorites, suggesting that extraterrestrial material may have played a role in the origin of life. The new technique allows for analysis of tiny samples, enabling future studies on cometary particles and sample-return missions.
University of Cincinnati researchers are developing validation metrics that could help predict the success or failure of hypersonic aircraft. The metrics involve principal component analysis (PCA) decomposition of simulation and test data to measure uncertainty, which will ultimately determine the success in building such a plane.
The American College of Physicians and the Centers for Disease Control and Prevention have released an updated adult immunization schedule for 2014. Key changes include the removal of health care worker vaccination as an indication and updated recommendations for certain adults at increased risk for Haemophilus influenza type b (Hib) i...
Research on a prospective payment system for ESRD improved patient access to care while reducing costs and mortality rates. The system created incentives to reduce high medication doses and higher-cost medications, saving taxpayers money.
Studies highlight the impact of clinical education on imaging examinations, including increased effectiveness and improved guideline adherence. Trends in diagnostic CT scans also reveal differential changes by age group and body region.
The study creates maps of habitat corridors connecting protected areas in the tropics to conserve biodiversity and mitigate climate change. The corridors provide opportunities for carbon sequestration and avoiding emissions from deforestation.
A group of experts has proposed concrete steps to prevent and manage drug shortages, including sharing scarce drugs and giving equal priority to patients. The 'blueprint for action' aims to move away from reactive strategies and focus on prevention, ensuring life-saving medications are accessible to children with cancer and beyond.
A three-and-a-half year trial found a significant reduction in cesarean deliveries and neonatal morbidity in hospitals implementing best practices and professional training. The study's results confirm that continuing education and internal audits can improve maternal and fetal health outcomes.
A meta-analysis study found that more than half of parents underestimate the weight of their overweight or obese child, regardless of age or obesity rates in their area. Parents' perceptions about their children's weight become more accurate with age.
Researchers at UC Davis have invented a technique to produce gasoline-like fuels from cellulosic materials like farm and forestry waste. This breakthrough could lead to a larger market for renewable fuels beyond existing diesel substitutes.
A new study emphasizes the importance of a data-driven team in launching and sustaining a School-Wide Positive Behavioral Interventions and Supports (SWPBIS) framework. The study found that an effective school-based team using data for decision-making was more critical to sustainability than principal support.
Belgian scientists applied a particle physics analogy to describe exciton behaviour in two graphene layers, mimicking parallel worlds. The approach reveals swapping effects between layers under specific electromagnetic conditions, similar to brane theory predictions.
Scientists have identified a genetic function called Grasp that plays a crucial role in maintaining the proper function of the p53 tumor suppressor gene. This discovery could lead to a new approach in cancer therapy by activating or stimulating the Grasp gene to enhance p53 function.
UW physicists debunk the 'heavy soliton' mystery by revealing it's actually a quantum equivalent of smoke rings, shedding light on nuclear dynamics and neutron star behavior. The research uses state-of-the-art computing techniques to demonstrate that virtually all aspects of the phenomenon can be explained by vortex rings.
A recent study published in the European Journal of Preventive Cardiology found a causal link between depression symptoms and an increased risk of coronary heart disease. In contrast, no such association was found with stroke risk. The Whitehall II study, which followed over 10,000 civil servants in the UK for 20 years, suggests that r...
A new study published in PNAS found that recording the activity of just 50 neurons can accurately capture the behavior of larger neural networks. This challenges decades-long research on response time and accumulator models in psychology and neuroscience.
New research suggests private exchanges like dark pools can actually improve price discovery in public markets by attracting less-informed traders. Well-informed investors may be unable to fill their orders quickly, prompting them to return to public exchanges for better liquidity.
A meta-analysis of 46 studies found that positive feelings about race or ethnicity are associated with fewer symptoms of depression and emotional problems. Minority youth who feel positively about their racial or ethnic identity tend to have better social interactions, self-esteem, and academic performance.
The James Webb Space Telescope is nearing completion, with all 18 primary mirror segments and four science instruments delivered to NASA's Goddard Space Flight Center. The telescope will be the most powerful space telescope ever built, capable of observing distant objects in the universe.
The number of excess deaths caused by hot weather in England and Wales is projected to surge by 257% by the mid-2050s due to climate change and population growth. The elderly, particularly those aged 75+, will be most at risk, with rising temperatures expected to lead to increased mortality.
A US study found that many adults consume more added sugar than recommended for a healthy diet, and this can increase the risk of death from cardiovascular disease. The study also suggests that regular consumption of sugary drinks is associated with an increased risk of CVD mortality.
A study by North Carolina State University and Harvard University found that murderers who committed homicide during robberies are more likely to commit crimes again when paroled. The motivation for murder was a significant predictor of recidivism rates.
A new study by London School of Hygiene & Tropical Medicine found that opening a new supermarket in a low-income community did not lead to significant changes in diet or reduced obesity rates. Despite improvements in residents' perceptions of food accessibility, only 27% of residents adopted the new supermarket as their main food store.
A new study found that financial and social hardships are a major contributor to hospital asthma readmissions among black children. Nearly 23% of black children were re-admitted within a year, compared to 11% of white children.
Researchers studied how a protein complex called Mre11-Rad50 reshapes itself to take on different DNA-repair tasks, revealing insights into its dynamic structure and biological outcomes. The findings could guide the development of better cancer-fighting therapies and more effective gene therapies.
Scientists at Rice University and Russia have calculated a road map for creating ultra-thin diamond films without high pressure. The 'phase diagram' outlines conditions necessary to turn stacked graphene sheets into flawless diamond lattices, with potential applications in nanocapacitors, electronics, and nano-optics.
A study published in Health Affairs found that the FDA's median rulemaking time is 7.3 years, with cost-benefit analysis associated with additional delays. The authors recommend improving efficiency and promoting transparency to reduce regulatory burdens.
Research by American Psychological Association found that single-sex schools do not offer advantages in academic performance or attitudes towards school. A comprehensive analysis of 184 studies involving over 1.6 million students worldwide showed trivial benefits, if any, for boys and girls in math and science subjects.
Researchers have developed a smartphone-based system that can locate buried avalanche victims using satellite navigation, promising faster and more precise rescue operations. The Galileo-LawinenFon system uses the combined signals of GPS, Galileo, and GLONASS satellite systems to pinpoint accident victims in seconds.
INRS received seven NSERC Strategic Project Grants, totaling $3.5 million, to tackle scientific and technological challenges in ITC, materials, and environmental sciences. The funding supports projects such as developing new broadband RF signal processing and infrared subcyclic impulse lasers.
Scientists discovered a female-specific hormone in blue crab eyestalks that regulates development of reproductive structures for mating and childcare. This hormone is required for maternal care and triggers development of special receptacles to store sperm, as well as hair-like structures to hold fertilized eggs.
A study by the University of York found that British people traveling abroad for medical treatment often lack understanding of potential consequences, including catastrophic outcomes. The research highlights the need for better information and advice to mitigate these risks.
Researchers at Vanderbilt University discovered that mosquito sperm contain a suite of specialized chemical sensors called odorant receptors, which drive the rapid increase in movement. These findings suggest a new paradigm for regulating insect reproduction and could provide a powerful approach for controlling insect populations.
A group of experts warn that high blood pressure could be as devastating to global health as HIV, with potentially more deaths over the next 20 years. Despite similarities between the two conditions, there is 'denial' and misunderstanding about hypertension's impact, hindering effective treatment and management.
A new approach may help doctors tailor treatments for women at risk of preterm birth by identifying genetic differences. Progesterone injections have been shown to reduce the risk of recurrent preterm births, but not all women respond to treatment.
A recent study found that the use of wasps to combat citrus greening disease is unlikely to threaten non-target insects. The parasitoid wasp Tamarixia radiata was tested against seven non-target psyllid species, with only one showing a low level of parasitization.
A new study published in Pediatrics reveals that HPV vaccine perceptions do not influence subsequent sexual behaviors in teenage girls and young women. The vast majority of participants maintained safer sex habits after vaccination, regardless of their beliefs about the vaccine's effectiveness.
A recent study by Group Health Research Institute found that patients with treated hypertension had 27-28% fewer specialty visits after implementing a patient-centered medical home. In contrast, clinically complex patients with multiple diseases saw a 3-5% increase in specialty use during the first two years after implementation.
Cedars-Sinai researchers found that genetically targeting immune cells to overproduce ACE breaks down beta-amyloid plaque, preventing cognitive decline in laboratory mice. The study identifies a novel role for ACE in the clearance of beta-amyloid in brain blood vessels.
Researchers at the University of Edinburgh identified shugoshin as a critical protein in ensuring accurate cell division. The study found that disabling shugoshin led to increased abnormal chromosome numbers, highlighting its importance in preventing aneuploidy and potentially cancer.
Tropical Cyclone Fletcher has brought heavy rain to coastal areas in western Queensland and the Gulf of Carpentaria. The Australian Bureau of Meteorology expects further rainfall over the next couple of days, with maximum sustained winds estimated at 30 knots/34.5 mph.
Researchers at the University of Glasgow challenge the long-held view of six basic emotions by studying the temporal dynamics of facial expressions. They found that fear and surprise share a common signal, as do anger and disgust, suggesting only four basic emotions.
A new study by CU-Boulder researchers suggests that shy toddlers may not be delayed in language acquisition, contrary to common assumptions. The study found consistent evidence that shy toddlers understand what's being said, but are reticent to speak.
A study by Einstein researchers identified a chemical 'signature' in blood-forming stem cells that predicts which AML patients will respond to chemotherapy. The findings, based on nearly 700 patient data, could help physicians identify patients who would benefit from standard treatment and spare them debilitating side effects.
A new guideline from the Canadian Society of Nephrology recommends delaying dialysis for asymptomatic adults with chronic kidney disease, citing improved quality of life and cost savings. The 'intent-to-defer' strategy avoids the burden of early start, while still closely monitoring patients.
A new study reveals that adolescents consuming excessive salt are more likely to develop obesity and chronic inflammation. The research, published in the journal Pediatrics, found a significant correlation between sodium intake and fatness, even when calories were controlled for.
Researchers from Brigham and Women's Hospital found that blue light exposure improves alertness and performance during the day and night, reducing fatigue. The study used specialized equipment to compare the effects of blue and green light on 16 participants, showing significant improvements in alertness and reaction times.
Researchers used preimplantation genetic diagnosis (PGD) to identify mutation-free embryos and conceive healthy twins after a woman was diagnosed with a fatal genetic disorder. The treatment allowed for selective implantation of two mutation-free embryos, resulting in the birth of healthy twins.
Researchers found that routine delivery did not decrease maternal complications but increased neonatal respiratory distress syndrome, while expectant monitoring reduced risks in both mothers and babies. The study suggests that expectant monitoring should be considered for women with hypertensive disorders between 34-37 weeks of pregnancy.
The new field of macrosystems ecology is being touted as a solution to tackle environmental problems such as climate change and invasive species. By integrating biology with other fields and using vast amounts of data, ecologists can study complex systems at broad scales.
Researchers at Worcester Polytechnic Institute are investigating ways for robots to work alongside humans in settings like manufacturing plants and elderly homes. They aim to develop algorithms that enable robots to collaborate with people on tasks, enhancing productivity without compromising safety.
A new IUPUI study found that treating depression before cardiovascular disease onset can decrease the risk of future heart attacks and strokes. The study followed 235 older patients with depression, finding a 48% lower risk among those receiving collaborative care.
A new evidence review finds that fecal immunochemical tests (FITs) detect about 79% of colorectal cancers and correctly identify 94% of patients without cancer. The test is simple, can be done at home, and can save lives, making it a great tool for assessing which patients have cancer and which do not.
A landmark study by researchers found that women with schizophrenia are nearly twice as likely to experience pre-eclampsia, pre-term birth, and other serious pregnancy and delivery complications. The study also revealed high birth weights, increased rates of hypertension and thromboembolic disease in pregnant women with schizophrenia.
A new study published in Biological Psychiatry investigates the relationship between age and neurocognitive performance in 296 healthy volunteers. The researchers found that white matter tracts developed during adolescence and young adulthood are associated with learning, memory, and planning abilities.
A new nanoparticle system will recruit stem cells to regenerate arterial walls, reducing complications and extending patient lives. Researchers have discovered a way to use nanoparticles to help arteries heal more effectively following surgical procedures.
A study of over 76,000 women found that advanced maternal age is associated with a 40% decreased risk of major congenital malformations. Women aged 35 and older had lower incidence rates for brain, kidney, and abdominal wall defects, while heart defect rates remained unchanged.
A new study by researchers at ETH Zurich found that scientists have differing opinions on how to describe invasive plant species and their environmental impact. The study suggests that broader participation of different expert groups could lead to more effective invasive species management.
Researchers have determined the complex structure of a key cell membrane protein involved in sterol metabolism and resistance in a yeast model. The study's findings provide new insights into mechanisms underlying fungal resistance to triazole drugs, which can help develop new broad-spectrum drugs with minimal side effects.