Researchers are exploring a new therapy to eliminate the major risk of minor bleeding after stroke, focusing on diabetic patients who are at higher risk. The treatment involves an iron chelating agent that can remove excess iron from the brain, reducing damage and promoting recovery.
Scientists at the Hebrew University of Jerusalem have reported a major breakthrough in understanding the molecular basis for Prader-Willi syndrome (PWS), a disease that involves defects in parental imprinting. The researchers created a model for PWS by reprogramming skin cells from patients into embryonic-like cells, showing that pater...
Rice University synthetic biologist Jeff Tabor is working on a three-year project to engineer probiotic bacteria that can detect disease signals in the gut and prevent diseases such as obesity and depression. The goal is to create an edible probiotic bacterium that can help protect sailors and marines from these health issues.
The article highlights the potential of social enterprise businesses in creating employment opportunities for people with disabilities. The author, Elaine E. Katz, details two successful examples, Hudson Community Enterprises and Destination Desserts, which have generated revenue and provided market-driven pay rates for employees.
A study found that C-section deliveries and early antibiotic treatment may alter a child's microbiota, increasing the risk of developing eosinophilic esophagitis. The condition is marked by irritation, inflammation, and constriction of the esophagus, and its symptoms mimic garden-variety gastritis.
Researchers at JAX Laboratory have identified a protein involved in both wound healing and tumor growth as a potential therapeutic target. The study found that manipulating this protein could stimulate healing in wound patients while dialing back cancerous proliferation.
A new study published in JAMA Internal Medicine found no association between resveratrol consumption and improved health outcomes. The research suggests that the supposed health benefits of resveratrol from food sources may be exaggerated or entirely unwarranted.
The Banking on Solar working group aims to standardize contracts and underwriting processes, educating banks about the risks and rewards of solar assets. This effort has already begun developing standardized loan documents and underwriting criteria in residential and commercial markets.
A study found that parental disapproval is associated with lower rates of prescription drug misuse, particularly in African American and Hispanic teens. Strong parental disapproval of substance use was a stronger factor for these groups than peer attitudes.
A study published in Psychological Science found that finding a direction for life and setting overarching goals can help people live longer. The research analyzed data from over 6000 participants and found that greater purpose in life consistently predicted lower mortality risk across the lifespan.
Corneal nerve fiber assessment has great potential as a tool to diagnose and monitor peripheral neuropathy induced by HIV, say scientists at Johns Hopkins University School of Medicine. The study found that SIV-infected macaque model showed decreased corneal nerve fiber density and correlated with epidermal nerve fiber length.
A new study reveals that US cervical cancer rates are higher than previously believed, particularly among women over 65 and African-American women. The study found an age-standardized rate of 18.6 cases of cervical cancer per 100,000 women, with incidence increasing steadily with age.
Researchers found that miRNA-9 binds to and potentially reduces the activity of oligodendrocyte lineage gene 1 during hypoxic-ischemic brain injury. This regulatory mechanism may play a role in myelin repair and neurological disorder development.
A study published in Neural Regeneration Research found an unusual neural connection between the injured cingulum and brainstem cholinergic nuclei in a patient with subarachnoid hemorrhage. This phenomenon was detected using diffusion tensor tractography, revealing a novel pathway for neural communication.
A new study found that individuals recently released from prison or on parole have a significantly increased risk of visiting hospitals and emergency departments. The study suggests potential cost savings if preventive care can be provided through timely access to health insurance coverage.
Researchers identified potentially actionable mutations in cancers of the appendix using next-generation DNA sequencing. KRAS and GNAS mutations were found to be common alterations in both low-grade appendiceal mucinous neoplasm (LAMN) and adenocarcinoma tumors.
Researchers at Northwestern University developed a new metric to measure energy consumption efficiency in animals of different sizes. Contrary to expectations, the study found that the gray whale and skipjack tuna are almost equally efficient, with the whale's higher fuel consumption being an unavoidable consequence of physics.
Researchers found that college students were more likely to drive and ride after marijuana use compared to alcohol use. The study suggests that social norms regarding marijuana use are changing, leading to increased acceptance of driving under the influence of marijuana.
Research reveals prehistoric Europeans consumed psychoactive plants and fermented beverages in rituals to connect with the spirit world. Archaeological evidence suggests socially controlled use of these substances, contrasting with modern hedonistic views.
New targets for drug therapy have been identified in the mast cell system, including enzymes and receptors. These targets include serine proteinases tryptase, chymase, cathepsin G, and proinflammatory cytokines.
A novel plasma actuator improves plasma authority at high wind speeds, suppressing boundary layer separation and reducing model vibration on a UAV. The study demonstrates an important role of plasma actuators in real applications.
A comprehensive analysis of e-cigarette research reveals industry health claims are unsupported, and exposure is associated with indoor air pollution. E-cigarettes should be regulated to protect public health.
New prescription drugs are delayed in Canada due to pharmaceutical company submissions to Health Canada. The mean delay was 540 days for approved drugs submitted to the US and EU first.
Beaumont Children's Hospital has been awarded a $20,000 grant from CureSearch to support therapeutic clinical trials for children with cancer. The hospital believes that clinical trials are essential in helping children with cancer, and this funding will enable them to open additional studies and reach more patients.
Researchers at Université Laval have discovered a natural molecule called protectin DX (PDX) that improves insulin sensitivity and reduces blood glucose levels in obese diabetic rats. PDX triggers the production of interleukin-6 (IL-6) in muscle cells, similar to exercise, but its efficacy may be comparable to certain diabetes drugs.
Researchers have discovered a synthetic molecule that inhibits T-cell signaling in the lungs, preventing asthma symptoms such as inflammation and airway constriction. The molecule shows promise for treating asthma, a chronic disease affecting over 25 million Americans.
A study from North Carolina State University found that increases in dopamine levels trigger dramatic physical changes in Indian jumping ant workers, transforming them into warrior queens with elevated life expectancy. This discovery has implications for understanding social insect behavior and epigenetics.
The robotic arm, developed by EPFL researchers, is capable of catching projectiles with irregular shapes and trajectories. It achieves this through a combination of machine learning algorithms and real-time adjustments, enabling it to catch objects in less than five-hundredths of a second.
23andMe's new HaploScore algorithm improves IBD detection accuracy, enabling more accurate genetic relationships and ancestry reports. The open-source algorithm can be applied to existing IBD segments, differentiating between true and false positives.
Research suggests that economic conditions during the formative years of emerging adulthood can leave a lasting mark on individuals' self-concept. People who entered their adulthood during hard economic times are less narcissistic later in life than those who came of age during more prosperous times.
Researchers developed a self-administered program called 'Connecting' to guide foster families through exercises that bring them closer together. The program uses short videos of former foster youth describing their experiences in child welfare and encourages caregivers to share basic information with their teens.
A nationwide dataset analysis found that black women are 1.84 times more likely to be diagnosed with triple-negative breast cancer, a subtype with poorer prognosis. Asian/Pacific Islander women were also more likely to be diagnosed with HER2-overexpressing breast cancer.
Recent HADES experiments have ruled out the U boson as a potential Dark Matter candidate, but the search continues. The negative results challenge the Standard Model of particle physics and leave room for further investigation into physics beyond the current understanding.
Brookhaven physicists Mark Dean, Xin Qian, and Bjoern Schenke are awarded DOE funding to explore magnetic excitations in materials, develop detectors for precision neutrino measurements, and study high-energy nuclear collisions. The grants support research at Brookhaven National Laboratory.
Researchers identified a protein called CFIm25, which regulates messenger RNA length and promotes tumor growth. Restoring CFIm25 levels in brain tumors dramatically reduced their growth, providing a potential novel therapeutic strategy.
Researchers investigated the connection between small-vessel disease and Alzheimer's disease pathology, revealing a possible correlation with cognitive impairment. The study found that small vessel disease may contribute to the development of Alzheimer's-like pathology in the brain.
A new study suggests that US cervical cancer incidence rates may be underestimated due to the inclusion of women who have undergone a hysterectomy in calculations. Rates were found to increase with age, particularly among older women and black women.
Researchers from the University of Pennsylvania have combined graphene with a painkiller receptor to create an artificial chemical sensor. The device uses electrical responses instead of biochemical ones, allowing it to be read out by a computer. This technology has potential applications in drug development and various diagnostic tests.
NREL honored Principal Engineer Bhushan Sopori with the Distinguished Innovator Award for his leadership in solar energy research. The lab also recognized Rising Stars, including Kirstin Alberi, Arrelaine Dameron, and Gregg Beckham, who have made significant contributions to technology transfer and commercialization.
Researchers found that at least one in four Medicare recipients received wasteful services in 2009, resulting in $1.9 billion in unnecessary spending. The study used novel methods to measure low-value care and provides tools for evaluating reform efforts aimed at reducing waste.
A Purdue study reveals that reducing corn's growing conditions by 2 hours a day can lower its height by 9-10% and reduce stalk diameter by 8-9% while maintaining its seed yield. This technique could enable controlled environment agriculture in mines and caves for growing high-value transgenic crops.
The study analyzed low-value care in Medicare and found potential signs of overuse. It suggests that unnecessary services may be prevalent in the program, highlighting opportunities for improvement.
A recent study published in JAMA Pediatrics found that male circumcision is associated with a low rate of adverse events. The study suggests that male circumcision carries minimal risk and can be performed safely without compromising the child's long-term health outcomes.
Researchers at Henry Ford Hospital identified specific genes associated with improved survival rates among patients with glioblastoma, the most deadly form of brain tumor. The study found that patients over 70 were more likely to survive longer and that gender differences played a role in short-term survival rates.
Researchers found that smaller groups of countries are more likely to reach consensus, while side agreements among smaller numbers of participants can actually promote the UN process. The study also highlights the importance of perceived individual threat in maintaining successful negotiations.
A Pittsburgh Supercomputing Center and Johns Hopkins Bloomberg School of Public Health team used HERMES modeling software to help the Republic of Benin redesign its vaccine delivery system, saving an estimated $500,000 in costs while improving vaccination rates.
Treating ADHD with stimulant medication is associated with lower smoking rates, particularly in those taking the medication consistently. The study analyzed 14 longitudinal studies and found a significant association between stimulant treatment and reduced smoking frequencies.
A study published in the Proceedings of the National Academy of Sciences found that bullied children experience chronic, systemic inflammation that persists into adulthood. In contrast, bullies may benefit from increased social status through bullying, which can protect against increases in inflammatory markers.
Researchers have created magnetic bacteria that can help diagnose diseases like stomach cancer and are also edible iron supplements. These artificial magnets can be used in magnetic resonance imaging or heating malign cells.
A patient diagnosed with advanced, incurable lung cancer was found to have early stage, curable lung cancer after stopping a rare antibiotic that caused liver and lung damage. The team's findings suggest that toxicity due to the antibiotic may be mistaken for cancer spread.
A study published in Neural Regeneration Research found that pro-urokinase is more effective than urokinase in dissolving blood clots and promoting angiogenesis. However, it did not reduce neuronal apoptosis after acute cerebral ischemia.
New research finds that living near foreclosed properties increases risk of higher blood pressure, with each additional property within 100 meters associated with a 1.71 mm Hg increase in systolic blood pressure. This association may be due to unhealthy stress from perception of decreased property value and neighborhood instability.
Active learning improves exam performance, increasing grade gains by an average of 6%, and reduces student failure rates in STEM courses. By adopting this approach, tens of thousands of students could stay in STEM majors instead of flunking out, meeting national calls for a million more STEM graduates.
A new measure ranks US hospitals based on complications following hip and knee replacements, revealing a significant four-fold difference in risk-adjusted complication rates. The study found no disparities in outcomes between hospitals caring for higher proportions of Medicaid-eligible or black patients.
A University of Illinois initiative, Scientific Animations Without Borders (SAWBO), uses cellphones and local languages to educate farmers about efficient teff cultivation techniques. The project resulted in a massive reduction in teff seed waste, allowing for increased crop yields and food availability.
Berkeley lab researchers have discovered that the viral packaging motor rotates DNA in response to changing conditions, a crucial process for viral replication. This finding could lead to new strategies for combating viral infections and designing more effective drugs.
A recent study conducted by researchers at the University of Massachusetts Amherst and the University of Washington found that underage male college students who report using marijuana in the previous 28 days had a high prevalence of driving under its influence. The study also revealed that riding with a marijuana-using driver was more...
The Hydrogen Fueling Infrastructure Research and Station Technology (H2FIRST) project aims to reduce the cost and time of fueling station construction, increase station availability, and improve reliability. NREL and Sandia will share their hydrogen research expertise to develop low-cost, high-performance materials and components.
A German-Danish team of researchers found that endocrine-disrupting chemicals interfere with human sperm function, changing swimming behavior and triggering digestive enzyme release. The study suggests these chemicals may contribute to widespread fertility problems in the Western world.
Scientists at Ames Laboratory have developed a nanoparticle that can perform two processing functions at once for green diesel production. Using iron as the catalyst reduces costs and improves efficiency, making it a promising alternative to traditional biodiesel production methods.
Researchers successfully constructed an adenovirus that induces DHCR24 specifically in neuronal cells, leading to reduced apoptosis. The findings suggest potential for future studies on DHCR24 gene therapy and neuronal functional research.
Researchers found that aspirin inhibits wound healing by reducing the production of 12-HHT, a molecule promoting epithelial layer restoration. A synthetic BLT2 agonist accelerated wound healing in diabetic mice, suggesting potential treatments for chronic wounds.
Researchers at the Mount Sinai Hospital identified subtle changes in inhibitory signaling in the reward pathway, affecting how animals respond to drugs like cocaine. The study highlights sorting nexin 27 as a promising target for treating addiction and may lead to new therapeutic options.
A study published in the Journal of Ecology found that between 45-48% of the world's plants are woody, contradicting initial assumptions and expert opinions. The researchers developed a statistical method to account for sampling bias and made their data and methods openly available.
Researchers found that a diet rich in resveratrol did not reduce mortality rates or cardiovascular disease, contradicting previous expectations. However, they suggest that other polyphenols in these foods may still provide health benefits.
Researchers found that lava flows, not water, carved the massive Noctis Labyrinthus and Valles Marineris canyons on Mars. The study suggests that there was less water on Mars than previously thought, making life on the planet less likely.
Researchers used microfluidic devices to trap bacterial cells and bathe them in different solutions, revealing that cell walls grow regardless of external pressures. The study's findings challenge the prevailing wisdom on osmotic shock, which may lead to new strategies for fighting bacterial diseases.
The University of Chicago Medicine Comprehensive Cancer Center has been awarded a five-year, $3.9-million grant to serve as a Lead Academic Participating Site for the National Clinical Trials Network. The new network aims to improve cancer clinical trials' speed and efficiency.
A new study analyzing Michigan hospital data found that Medicaid patients who underwent surgery had twice as many health risk factors, more emergency operations, and two-thirds more complications than those with private insurance. They also used 50% more hospital resources.
Researchers at Kansas State University have identified a new gene expression mechanism in the porcine reproductive and respiratory syndrome (PRRS) virus. The discovery provides a potential avenue for developing new antiviral strategies.
A new treatment option has been discovered that could protect frogs in zoos from a deadly fungal infection, reducing the reliance on often-toxic itraconazole. Amphotericin B is shown to be less toxic than itraconazole and can be combined with itraconazole for effective treatment.
A study published in CMAJ found that pregnant women are at a higher risk of serious traffic crashes during the second trimester, with a 42% increase in crashes compared to baseline. The researchers emphasize the importance of safe driving practices, such as avoiding excessive speed and minimizing distractions, to prevent accidents.
A UCI-NASA study reveals six massive glaciers in the Amundsen Sea sector are in irreversible decline, contributing significantly to sea level rise. The glaciers contain enough ice to boost global sea levels by 4 feet and are melting faster than expected.
A team of USC and NYU researchers has developed a small molecule that interferes with cancer progression by mimicking the surface topography of one protein, tricking another into binding with it. This stops an aberrant gene expression contributing to cancer growth with minimal side effects.
Researchers analyzed data on nearly 3,000 hospitals from 2006 to 2011, finding that financially weak and safety-net hospitals struggled to recover from the recession. Despite rebounding by 2011, these institutions continue to face significant financial gaps with non-safety-net hospitals.
Researchers at Ohio State University have developed a novel strategy for treating multiple myeloma by genetically modifying T lymphocytes to target the CS1 molecule on myeloma cells. The modified cells were shown to efficiently destroy human multiple myeloma cells in laboratory studies and animal models.
A study published by INFORMS finds that analyzing pre-release consumer buzz can forecast new product sales more accurately than traditional methods. The research also reveals a key link between online buzz and firm stock prices, allowing for immediate capitalization on the new product.
Researchers discovered that FOXM1 and CENPF genes synergistically activate pathways associated with the most aggressive form of prostate cancer. The study identified these genes as a key driver pair in both mice and humans, and found that co-expression correlated with poor disease outcomes.
Researchers found an estimated 9 million people with diabetes and 5.6 million people with coronary artery disease are not receiving statins, highlighting a concerning trend driven by high cholesterol. Statin use is often associated with reduced cardiovascular risk, regardless of cholesterol levels.
Michigan State University researchers identified a gene mutation in Doberman pinschers that causes albinism, similar to humans. The study found over half of albino dogs developed tumors, while only one regular-colored dog did.
Researchers at UBC have discovered a key enzyme, MMP12, that plays a crucial role in deploying the antiviral protein Interferon alpha. The team has developed a new drug that blocks this enzyme, keeping Interferon alpha levels high and boosting the immune system's response to viral infections.
Researchers conclude that Antarctica's West Antarctic Ice Sheet will likely disappear within a few decades, with the Thwaites Glacier disappearing in centuries. The ice sheet contains enough ice to cause another 3-4 meters of global sea level rise.
A study found that people exposed to paint, glue, and degreasers at work are at risk for memory and thinking deficits decades after exposure. The research suggests that high lifetime exposure can lead to cognitive problems regardless of when the exposure occurred.
Researchers at University of California - San Francisco have developed a new cancer immunotherapy that manipulates the thymus gland to alter its activity, allowing specialized immune cells to battle cancer cells. The treatment has been shown to be effective in treating deadly melanoma skin cancers in mice.
A recent study published in Pediatrics suggests that children exposed to a parent's nicotine-dependent smoking are at a higher risk of becoming heavy smokers themselves. Parental smoking cessation early on is crucial to prevent habitual smoking in the next generation.
The NREL-Navy collaboration demonstrated eight energy-efficient technologies, yielding valuable results for the U.S. Navy. Advanced power strips and building retrofits achieved measurable savings, with plug load control technology reducing overall energy consumption by 8% in an office setting.
A landmark study shows that intensive insulin treatment significantly improves survival in patients with type 2 diabetes who have had a heart attack. The trial, which followed patients for up to 20 years, found that those who received intensified insulin treatment survived an average of 2.3 years longer than those on standard treatment.
Scientists have identified two alternative pathways that compensate for the lack of corpus callosum, enabling communication between brain hemispheres. These pathways are found to be functional and play a crucial role in tactile recognition abilities, similar to those observed in individuals with normal corpus callosum.
A new measurement model reveals that human rights are actually improving, contrary to common claims. The model takes into account changes in data collection and categorization, showing more countries with better human rights records.