A new study found that nearly two-thirds of patients treated for stage 3 colorectal cancer reported some measure of financial burden due to their treatment. The burden was greatest among patients who received chemotherapy and younger patients in low-paying jobs.
Researchers leverage magnetically heated nanoparticles to overcome heat transfer limitations in cryopreservation, enabling rapid thawing of large biomaterials. The technology offers tunable heating rates and can accommodate unloaded sections up to several millimeters in dimension.
Tropical Storm Ana has re-organized due to abating southwesterly wind shear, allowing thunderstorms to circulate around its center. The storm is expected to continue strengthening through early Saturday, moving northward and potentially becoming a hurricane.
A nationwide study found that US doctors spend an average of 8.7 hours per week on administration, including tasks such as billing and insurance approvals. The study also revealed that physicians in Canada spend less time on administrative work due to their single-payer system.
A new study predicts that current international efforts to combat the Ebola outbreak in Montserrado, Liberia, will not be sufficient to contain the epidemic. The research estimates that up to 170996 total cases and 90122 deaths are projected by December 15, 2014, without expanded control measures.
A study of 51,785 individuals with kidney stones found a significant link between the condition and an increased risk of bone fractures. The excess risk was greatest in males during adolescence and women during middle age.
Researchers discovered that Topoisomerase II is required to resolve DNA threads connecting homologous chromosomes, allowing them to separate. Without this enzyme, chromosomes get stuck together, preventing meiosis from completing and resulting in infertility and birth defects.
Rapid lowering of body temperature after a heart attack can minimize damage to the heart muscle. New research highlights the need for faster and more effective cooling techniques to realize the full potential of therapeutic hypothermia.
A new study suggests that modifying grocery store environments can encourage healthier food choices among children. Researchers propose strategies like placing healthy options at eye level, allowing sample tastings, and offering cooking classes.
Researchers at the University of Houston are developing new nanofiltration methods to remove salt from brackish waters, a potentially cheaper alternative to existing desalination techniques. The methods could help alleviate drought-stricken regions' water scarcity issues.
Researchers at the Wyss Institute have developed synthetic gene controls that can be used to create programmable diagnostics and biosensors, which can detect specific diseases or infections using saliva or a drop of blood. The new tools are delivered on pocket-sized slips of paper, making them portable and accessible for widespread use.
Researchers found that reduced levels of SNX27 protein lead to increased beta-amyloid production and brain plaques, a hallmark of Alzheimer's disease. Adding new copies of the SNX27 gene can repair memory deficits in Down syndrome mice.
A comprehensive analysis of thyroid cancer has identified markers of aggressive tumors, which could lead to better targeting of treatments. The study suggests the potential to reclassify the disease based on genetic markers and moves thyroid cancer into a position to benefit from precision medicine.
Zoos and aquariums are vulnerable to disasters, but experts say preparedness training and planning can minimize risks. The University of Illinois veterinarian Yvette Johnson-Walker brings emergency training to accredited institutions, focusing on scenarios like avian influenza and hurricane floodwaters.
Astronomers at Ohio State University have observed a star narrowly escaping capture by a supermassive black hole, releasing only a small portion of its mass. The event, known as a tidal disruption event (TDE), provides valuable insights into the growth and behavior of black holes in the universe.
A recent study by Bradley Hospital found that sleep difficulties, particularly problems with falling asleep, are very common among toddlers and preschool-aged children with psychiatric disorders. The study highlights the importance of addressing sleep problems in young children to improve behavioral adjustment and wellbeing.
The new lattice light sheet microscope collects high-resolution images rapidly, minimizing damage to cells. It enables biologists to visualize the three-dimensional activity of molecules, cells, and embryos in fine detail.
A new study published in The Lancet Infectious Diseases predicts that the Ebola epidemic in West Africa will worsen unless international aid is significantly increased. The model developed by Yale researchers estimates tens of thousands of new cases and deaths by December 15 if current efforts are not intensified.
Researchers found that dissolved oxygen levels significantly impacted scavenger response on submerged carcasses. In areas with low oxygen levels, smaller creatures like squat lobsters were unable to break through the skin, while larger ones were kept out.
Scientists have discovered that PP4 protein oversees DNA processing during sperm and egg generation for successful fertilization. The study found that PP4's activity becomes more crucial during aging, indicating a potential role in age-related fertility declines.
A recent study published in Nature found that no-till farming often leads to yield declines compared to conventional tillage systems, except in dryland areas where it can show promise. Implementing all three conservation agriculture principles is crucial for maximizing yields and minimizing environmental impacts.
Researchers at St. Jude Children's Research Hospital identified a promising triple-drug combination therapy that exploits DNA repair problems in Ewing sarcoma tumors, showing over 70% success rate in mice treated with the combination of chemotherapy drugs and PARP inhibitors.
Researchers found that recreational drug use among swingers was associated with high-risk sexual behavior and STIs, especially in women. The study suggests that targeted interventions addressing safer sex practices and secondary prevention of drug use could be effective in reducing the spread of STIs.
At nearly 4,500 meters above sea level, a team led by University of Maine researchers has discovered the highest altitude ice age human occupation, dating it to around 12,000 years ago. This finding pushes back the known high-altitude habitation period by nearly a millennium.
Researchers use advanced technology, including analytic morphomics, to distinguish between mucinous and non-mucinous cysts. This innovative approach has the potential to reduce unnecessary surgeries and surveillance for patients with pancreatic cysts.
Scientists discovered that cells organize themselves to influence communication within a group. By forming huddles, cells trap and concentrate signals like FGF, enabling them to make decisions that affect organ formation and behavior. This strategy may play a role in wound repair and cancer.
Researchers developed a non-invasive method to detect Aspergillus fumigatus and other fungi causing pneumonia by analyzing patients' breath samples. The test identified 94% of patients with invasive aspergillosis, making it a potential tool for earlier and more targeted treatment.
A study found that a gut bacterium, Csp_P, can reduce infection of mosquitoes by malaria parasites and dengue virus. The bacterium directly inhibits these pathogens in test tubes and shortens the life span of mosquitoes that transmit both diseases.
A team of UT Arlington Computer Science and Engineering students won the NTx Apps Challenge with a smart traffic light network that analyzes traffic conditions in real time. The GridLock system enhances traffic flow, reducing congestion and jams.
UC San Diego has been designated as one of three 'alpha clinics' by the California Institute for Regenerative Medicine to accelerate clinical development of emerging stem cell therapies. The designation will support the establishment of a comprehensive regenerative medicine clinical hub and attract patients, funding agencies, and study...
Researchers discovered high-altitude Pleistocene sites in Peru, including Cuncaicha and Pucuncho Basin, indicating humans survived at altitudes over 4,400m. The findings suggest that people may have lived in these areas for extended periods without genetic adaptation.
A recent study found that most US adults fail to meet daily nutrient recommendations, with those with disabilities having poorer nutrition. The research highlights the need for policymakers and activists to address nutritional challenges faced by people with disabilities.
A European multicenter harmonization study reveals that standardized semi-quantitative anaplastic lymphoma kinase (ALK) IHC is reliable and comparable to FISH testing for detecting ALK protein expression. The study showed 100% concordance among institutions on 15 well-characterized NSCLC specimens, making IHC a potential stand-alone test.
The National Research Mentoring Network aims to address disparities in biomedical research by connecting underrepresented groups with mentors and opportunities. The five-year initiative, led by Professor David Burgess at Boston College, will draw on expertise from four universities and a consortium of academic institutions.
Researchers found that birds grouped together are less susceptible to West Nile virus infection, with a significant decrease in exposure compared to solo birds. This phenomenon, known as the 'encounter-dilution effect', suggests that individual risk is minimized when multiple birds roost together.
Scientists gathered crucial information on upper-level wind shear affecting Hurricane Edouard using NASA's HS3 mission Global Hawk. The hurricane strengthened during the sixth flight, with data showing a sea-level pressure of 969-970 millibars near the eye/eyewall border.
Desert streams have surprisingly simple topography despite being shaped by flash flooding, according to researchers from UCSB's Earth Research Institute. The stream's form is maintained by complex interactions among rainstorms, sediment flows, and sediment grains present on the riverbed.
A new study found a significant increase in type 1 diabetes rates among non-Hispanic white youth, with the highest rate of increase seen in children aged 5-9. The study, based on data from over 2 million children and adolescents, suggests that these trends will continue to be monitored to identify potential causes.
A study published in International Journal of Behavioural Nutrition and Physical Activity found that later sunsets may lead to increased children's physical activity. The research examined associations between sunset time and physical activity levels across 23,000 children in nine countries, with findings suggesting that children's tot...
Researchers call for networks of marine protected areas, co-ordinated governance, and local community involvement to tackle overfishing and habitat destruction. Small-scale fisheries, which involve 90% of the world's fishers, are a major threat, with destructive practices like bottom trawling causing widespread damage.
A study of 4,379 participants found that having AMD in one eye increases the risk of developing AMD in the other eye, with more severe disease progressing faster. The researchers tracked AMD severity in both eyes over a 20-year period and found a strong correlation between the two eyes.
A new study found that mothers with gestational diabetes and those who were overweight before pregnancy have daughters who are more likely to be obese. The research, published in Diabetes Care, suggests that behavior modifications during pregnancy may help reduce the risk of obesity in offspring.
Physicist Pierre Ramond has been awarded the 2015 Dannie Heineman Prize for his groundbreaking contributions to supersymmetry and superstring theory. His work provides a compelling picture of the universe, with tiny string-like objects vibrating to form particles.
A novel software application, CANARY, can automatically analyze high-resolution CT images to classify early-stage non-small cell lung cancer patients into risk groups. The tool was developed at Mayo Clinic and demonstrated accurate stratification of patients into categories with different 5-year disease-free survival outcomes.
A recent report in the Journal of Bone and Joint Surgery has highlighted the potential issue of flexible reamer breakage during single-bundle ACL reconstruction. This has prompted a 'Watch' from JBJS to alert orthopaedic surgeons about the problem. The 'Watch' aims to help surgeons avoid similar mishaps by understanding the causes and ...
Researchers have developed a new method for using engineered gene circuits in a cell-free, paper-based system to detect deadly viruses like Ebola. The low-cost platform could enable rapid detection of different strains of the virus.
Researchers discovered flu virus exploits aggresome, a cellular waste bundle, to release genetic material. The process takes 20-30 minutes and is gradual, with the virus tricking the waste pickup and disposal system.
New research reveals that obese children with asthma often mistake symptoms of breathlessness for a loss of asthma control, resulting in excessive use of rescue medications. This misunderstanding can lead to anxiety, reduced quality of life, and increased healthcare utilization.
A new test developed by researchers at the University of Manchester can identify congenital hyperinsulinism in some patients without known genetic causes. The test measures hormone levels and may influence treatment options, including avoiding pancreatic removal.
Children in high-quality early childhood education and care centers are less affected by changes in family income. Research found that low-income families' children exhibit more behavioral issues when their income decreases, but those attending regulated centers show stable levels of internalizing problems.
UC Riverside researchers have identified a new molecular mechanism for resistance and susceptibility to Fusarium oxysporum, a common fungus causing wilt in tomato plants. The study reveals that microRNAs play a crucial role in regulating gene expression, with specific targets contributing to resistance.
Genomic analysis of Rapanui people reveals significant contact with Native American populations between AD 1300 and AD 1500, suggesting a pre-European trans-Pacific route. The findings challenge traditional textbook versions of human colonization events.
A clinical trial in Sub-Sahara African countries shows a four-month TB treatment is well-tolerated and works for subsets of patients, but is not an alternative to the standard six-month treatment. The new regimen was beneficial for patients without lung cavitation, undernourished individuals, and those living with HIV.
The Department of Environmental Quality has awarded a $1.6 million grant to continue the water cleanup project at the Tar Creek Superfund site, led by Professor Robert Nairn and his team. The project aims to restore balance to the communities and wildlife in northeast Oklahoma.
A new study by Peter M.A. Toivonen reveals that cherry producers need to understand the intricacies of production-harvest-marketing continuum to successfully move sweet cherries from growers to end consumers. The study shows that temperature management is crucial for retaining fruit quality during long-term containerized shipment, and ...
Researchers have designed a new experiment to test the foundations of quantum mechanics at large scales. They plan to achieve macroscopic high-mass superpositions by using a levitated silicon nanoparticle in an interferometer setup.
Research at Brown University found a significant association between self-reported dispositional mindfulness and improved cardiovascular health, including lower BMI, physical activity, and fasting glucose. The study suggests that mindfulness training may be effective in increasing cardiovascular health indicators.
A recent study published in The Lancet highlights the need for comprehensive policy changes to address homelessness. Homeless individuals are not only sick physically and mentally but also have lower life expectancy.
A study by Northeastern University researchers found evidence of price discrimination on four general retailers and five travel sites, with significant price differences in some cases. The team examined 16 popular e-commerce sites using a sophisticated methodology to identify price steering and discrimination.
Researchers at MD Anderson Cancer Center discovered a new 'reader' protein, YEATS, that plays a crucial role in gene activation and DNA packaging. The study suggests that manipulating YEATS domains could lead to the development of new cancer treatments.