A study from the University of Sydney reveals a 61% decrease in genital wart management among young women since the introduction of the free HPV vaccination program. The vaccine has been effective in reducing genital warts and their treatment costs, with no significant change in other sexually transmitted infections.
A new study found that an electronic nose can identify distinct sub-groups of asthma in children, differing in age and symptoms. This discovery may enable healthcare professionals to tailor treatment to each individual, improving diagnosis and outcomes.
A new antifungal, isavuconazole, has been shown to be as effective as an existing drug, voriconazole, in treating invasive mold disease in cancer patients. Isavuconazole had significantly fewer drug-related adverse events than voriconazole, particularly in the eye, skin, and liver.
A new study suggests that eating before TB treatment can reduce drug effectiveness due to lower blood concentration levels. The study found significant implications for clinical practice, highlighting the need for correct medication administration.
A new lab test, Carba NP, has been developed to detect carbapenem-resistant Enterobacteriaceae (CRE) in just 2.5 hours, with a specificity of 100%. The test is highly sensitive and specific for detecting carbapenemase production, making it a crucial tool for preventing the spread of CRE.
A genetic mutation caused by ultraviolet light is linked to millions of human skin cancers, according to Stanford researchers. The mutation occurs in the KNSTRN gene and can cause genomic catastrophe, leading to cutaneous squamous cell carcinomas.
A phase II clinical trial combining Sorafenib and Selective Internal Radiation Therapy (SIRT) achieved improved patient survival, with median overall survival of 20.3 months for intermediate stage HCC patients. The treatment also showed promise in downstaging locally advanced HCC to potentially curative treatment.
A new study found that sleeping on animal fur in the first three months of life may reduce the risk of asthma in later childhood. The research, presented at the European Respiratory Society International Congress, suggests that exposure to animal skin and fur could have a protective effect against asthma and allergies.
Researchers found that age-related decline in skeletal muscle stem cell function is caused by increased activation of the JAK/STAT signalling pathway. Inhibiting this pathway with specific drugs restores muscle stem cell function and promotes tissue repair.
Researchers at Penn State have developed a new route to making graphene through intercalation, allowing for the creation of single-layer sheets without damaging the layers. This breakthrough could lead to easier and more efficient production of graphene for various industrial applications.
Researchers at Sanford-Burnham Medical Research Institute have developed a novel technique to promote tissue repair in damaged muscles. Cyclic bursts of a STAT3 inhibitor can replenish muscle stem cells, leading to their differentiation into muscle fibers, which could provide a new therapeutic approach to treating muscle diseases.
Researchers discovered that Axl and Mer receptors work in different settings to recognize and engulf dead cells. The study found multiple critical differences between the receptors, including their ligand use and regulation.
Researchers develop a new method called synthetic fermentation to rapidly synthesize large numbers of bioactive molecules using just a few building blocks. The method enables the generation of about 6,000 unnatural peptide-like molecules directly screened for biological activity without purification.
Researchers developed a prototype detector that sees an extraordinary broad band of wavelengths, including terahertz waves invisible to the human eye. The detector uses graphene and is more than a million times faster than existing room temperature detectors.
A new study in France has found that flour is the main cause of occupational asthma, affecting 20% of cases. The study also reveals higher incidence rates among skilled and unskilled workers, particularly those working in food product manufacturing.
Scientists at the University of Rochester have isolated key steps in ribosome formation, a crucial process for bacterial growth. The researchers found that multiple pathways of RNA processing occur simultaneously, suggesting new possibilities for stopping super-bugs.
Researchers at the University of Adelaide have made significant advances in crystallography, allowing them to study chemical reactions in their native state. The new technique uses a metal-organic framework to bind reactants and enables the examination of reaction products without isolating or growing crystals.
A randomized trial of 101 patients with chronic obstructive pulmonary disease found that benralizumab had no effect on acute exacerbation rates. However, subgroup analyses indicate the need for further investigation into the use of benralizumab in patients with COPD and eosinophilia.
Researchers developed synthetic platelet-like particles that can augment natural blood clotting, potentially reducing trauma-related bleeding deaths. The particles were tested in animal models and human blood, showing effectiveness in slowing bleeding without causing adverse effects.
A hospital stay significantly increases the risk of acquiring a multidrug-resistant infection, with each additional day boosting the likelihood by 1%, according to new research. The study found that the percentage of infections classified as multidrug-resistant rose sharply after four or five days of hospitalization, peaking at over 35%.
Research published in The Lancet HIV reveals that polydrug use is common among HIV-positive men who have sex with men (MSM) in the UK, and is strongly linked to condomless sex. Condom use was markedly lower with increasing polydrug use.
Patients living with COPD want to discuss their palliative care needs with healthcare professionals, but feel uncomfortable bringing it up due to fear of burdening others. Healthcare professionals should not be afraid to initiate conversations about palliative care, as patients understand the seriousness of their condition.
A mandatory employee vaccination policy at Henry Ford Health System resulted in a significant increase in flu vaccination rates, reaching 99% among health care workers. The system's success can be attributed to effective communication, education, and sufficient vaccine availability.
A new single-dose influenza drug, peramivir, shows promise in alleviating flu symptoms, including fever and viral shedding, when administered within 48 hours of symptom onset. It effectively reduces median time to alleviation of symptoms by 22 hours and is generally safe and well-tolerated.
A hospital-wide program in New York reduced antibiotic use by half and saved over $600,000 annually. Antibiotic stewardship also led to a significant decrease in antibiotic-resistant infections.
Scientists applied iPS cell technology to a transgenic nonhuman primate model of Huntington's disease, developing cellular features of the condition and discovering potential therapies for oxidative stress. This approach could aid in the discovery and evaluation of other treatments for the disorder.
A recent study has shown that the addition of carboplatin and/or bevacizumab to standard chemotherapy regimens can significantly increase pathologic complete response rates in stage II-III triple-negative breast cancer patients. This may lead to improved outcomes and reduced risk of relapse.
The University of South Florida will partner with three fire departments to test the effectiveness of supervised exercise programs and web-based interventions on reducing low back pain and disability. The study aims to identify safe and effective exercise interventions for firefighters at risk of back injury.
A study found that modern methods for predicting species distributions under climate change often leave out rare and threatened species. In Africa, over 90% of listed species are missed by popular tools, despite these species being critical to conservation efforts.
The Cardinal Health Foundation awarded Virginia R. Litle, MD, a Thoracic Surgeon at Boston Medical Center, grant funding to study the efficacy of a Caprini Risk Assessment Model and implement an efficient anticoagulation compliance protocol. The initiative aims to reduce venous thromboembolism complications after thoracic surgery.
The new Competence Center for High Performance Computing in the Natural Sciences will facilitate interdisciplinary collaborations and provide improved HPC services. The center will focus on research and application optimization, with a strong emphasis on Big Data and hardware accelerators.
A retrospective single-center study found that restarting infliximab therapy after a drug holiday is safe and effective for IBD patients. The average duration of infliximab holiday was 15 months. Patients who were in remission at the time infliximab was discontinued showed a 78 percent response rate at one year.
Three Clemson startup companies, VRM Labs, ConnectTiss LLC, and Addictive Drug Delivery LLC, have received $25,000 in seed money from the University Sponsored Application Program. The companies are commercializing technologies developed at Clemson to address various industries such as pet food, aging skin, and surgical meshes.
A combination therapy of two miRNAs, let-7 and miR-34, has been shown to suppress tumor growth in an animal model of non-small-cell lung cancer. The study offers a promising therapeutic avenue for this aggressive malignancy.
Research on e-cigarettes reveals potential links to asthma and emphysema, as well as a successful quitting aid, but also raises concerns about long-term effects and lack of consensus among doctors. The ERS Congress emphasizes the need for strong regulation to protect vulnerable populations.
Researchers at Technical University of Munich have discovered a new site where T lymphocytes can be programmed to attack pathogens. The liver plays a key role in this process, and synthetic messenger Hyper-IL-6 has been found to efficiently activate T cells, offering a promising new adjuvant for vaccine formulations.
The TRMM satellite calculated heavy rainfall generated by Hurricane Norbert and Tropical Storm Dolly. Rainfall totals were greater than 300 mm, affecting the open waters of the Pacific Ocean and near Mexico's western and Gulf coasts.
Research reveals that brown tide algae can survive and thrive in conditions degraded by human activity, such as low light and high organic nutrients. The study also highlights the unexpected ability of these algae to pump toxic arsenic out of their cells into water.
Researchers Brooke Feeney and Nancy L. Collins identify two support functions that help individuals thrive through close relationships: source of strength (SOS) support and relational catalyst (RC) support. SOS support enables individuals to cope with stress, while RC support fosters opportunities for growth and positive well-being.
Researchers at UT Southwestern Medical Center have identified several new genetic causes of Wilms tumor, a type of kidney cancer found only in children. The most common mutations were found in genes called DROSHA and DICER1, which affect the production of microRNAs that control cell growth.
A new blood test developed by researchers at the University of Manchester and The Christie NHS Foundation Trust may soon be used to tailor treatment for ovarian cancer patients. The test predicts patient response to targeted therapies such as bevacizumab, allowing for personalized treatment plans while sparing those unlikely to benefit.
A team of scientists used the Hyb-Seq method to sequence hundreds of nuclear loci and plastomes from milkweeds, providing a significant advance over previous methods. This approach combines target enrichment and genome skimming to reduce genomic complexity and increase sequencing efficiency.
The California blue whale population has rebounded to near historical levels, according to new research. The recovery is attributed to careful management and conservation measures, rather than ship strikes or other human-caused factors.
Researchers at Syracuse University have created biomimetic sacs that undergo spontaneous oscillations and tunable frequency, mimicking the behavior of living cells. The discovery has significant implications for the development of artificial cells and clocks.
Researchers found that banked blood membranes become stiffer over time, decreasing the cells' functionality and ability to carry oxygen into tiny microcapillaries. This decrease in functionality can lead to major clinical problems, such as impaired oxygen transport in the brain.
A population-based case-control study found no evidence that wearing a bra increases the risk of breast cancer among postmenopausal women. The study analyzed bra-wearing habits in relation to breast cancer risk using a rigorous epidemiological study design, providing reassurance to women about their bra-wearing habits.
A study published in PLOS ONE suggests that domesticated peaches can be traced back to the lower Yangtze River Valley in Southern China around 7,500 years ago. The researchers analyzed ancient peach stones and found significant growth in size over time, indicating intentional breeding and selection.
The Glanville fritillary genome, approximately 390 million base pairs long, has been fully sequenced at the University of Helsinki. The study confirms a key hypothesis about the ancestral lepidopteran species' chromosome count, revealing stability over 140 million years.
A new vaccine candidate, GP2, has shown a 57% reduction in recurrence rates among high-risk breast cancer patients. The vaccine targets CD8+ cells and was combined with an immune stimulant to enhance its effectiveness.
A new study confirms a strong link between air pollution and lung health in European adults, with people suffering from obesity particularly vulnerable. The findings emphasize the importance of educating about clean air and urge policymakers to update guidelines to meet WHO-recommended air quality standards.
Researchers found that adopting the USDA's 'Dietary Guidelines for Americans, 2010' would lead to a 12% increase in diet-related greenhouse gas emissions due to increased consumption of dairy products and seafood. In contrast, reducing daily caloric intake while shifting to a healthier diet would result in only a 1% decrease in emissions.
The report highlights how stigma, including public and structural forms, prevents individuals from seeking mental health care. Effective approaches to addressing stigma, such as promoting personal stories of recovery and enhancing support systems, are identified.
A new study from the University at Buffalo Research Institute on Addictions found that female college students who experienced severe sexual assault were three times more likely to experience severe sexual assault the following year. The researchers also discovered that women who have been victims may need to be followed for months to ...
The project aims to create a mobile app that enables park visitors to learn about the park's history, ecology, and scientific features while contributing to citizen science. The app will be available for download on Apple and Android devices and will allow users to log in and save their findings.
A new study found that caffeine therapy for apnea of prematurity does not have long-term harmful effects on sleep or control of breathing in children. The study, which assessed 201 preterm children at ages 5-12, showed no evidence of long-term detrimental effects of caffeine treatment on sleep duration or sleep apnea during childhood.
Researchers found that a flu virus can inflame nasal tissue and increase bacterial growth, leading to middle ear infections. The study suggests that the flu virus modifies the immune system's response to certain bacteria, enabling them to infect the middle ear.
Researchers from Moscow Institute of Physics and Technology published experimental data on jet fuel combustion, defining induction periods for various temperatures, pressures, and blending ratios. The study focuses on kerosene, a complex mixture of hydrocarbons, and aims to validate kinetic models for its burning.
Researchers have created a high-entropy alloy that exhibits exceptional damage tolerance, tensile strength and fracture toughness values, even improving its properties at cryogenic temperatures. The alloy's unique nano-twinning phenomenon contributes to its remarkable mechanical behavior.
Researchers have uncovered how bacteria control their growth and division by destroying key proteins through regulated protein degradation, a critical process for bacterial virulence. Understanding this mechanism may lead to the discovery of new antibiotics targeting pathways that allow bacteria to overcome stressful conditions.
Scientists at the University of Liverpool have discovered that changes in messenger molecule mRNA creation and destruction rates contribute to osteoarthritis. The study highlights key genes involved in the disease and offers hope for developing targeted therapies.