Researchers at Children's Hospital Los Angeles have shown improved outcomes in using stem cell transplantation to treat juvenile myelomonocytic leukemia (JMML), a rare form of chronic blood cancer. The study found that half of patients can be cured from their disease, and a potential standard conditioning regimen has been identified.
The ASBMB's Minority Affairs Committee has received a $500,000 NSF grant to support its Interactive Mentoring Activities for Grantsmanship Enhancement (IMAGE) program. The program aims to promote diversity in the scientific workforce by providing grantsmanship skills and career-development strategies to postdoctoral fellows and early-c...
Researchers found that lack of confidence, physical and mental impairments, and environmental factors hinder people with MS from engaging in meaningful activities. Building confidence is crucial to overcome these barriers and promote healthy behaviors.
Researchers develop a new method to create highly stretchable conductors by aligning carbon nanotubes with rubber cores, resulting in an impressive 1000% stretch-to-conductivity ratio. This innovation has significant implications for future medical devices, optical elements, and robotics.
Researchers at the University of Leicester and CNRS have observed the growth of free nanoparticles in helium gas, revealing new information about their structure. The study found that nanoparticles grow by clustering together under increasing pressure, similar to decaffeination processes.
NASA's Aqua satellite captured infrared data showing cloud top temperatures as cold as -63F/-53C on July 23, indicating potential heavy rainfall. The tropical depression is moving away from the Philippines in a north-northeasterly direction with maximum sustained winds near 25 knots.
Researchers at Sanford Burnham Prebys Medical Discovery Institute have discovered a new way to improve liver cancer treatment by blocking the activity of the lymphotoxin-beta receptor. The approach, which combines drugs currently in clinical trials with those targeting oncogene signals, may lead to improved patient outcomes.
The University of Montana research team, led by Sarj Patel and Tom Rau, will conduct expanded testing on biomarkers for traumatic brain injury. They aim to clinically validate their research and explore chronic traumatic encephalopathy.
A study found that certain combinations of gut bacteria, such as those from the Porphyromonadaceae and Lachnospiraceae families, resist colonization by C. difficile in mice. The researchers developed a computer model that accurately predicted C. difficile's success rate for other mice based on their gut microbiome composition.
Researchers developed a web tool to estimate the impact of genetic modification of mice, which can complicate biomedical research interpretation. The tool aids in explaining controversies and improving translation from lab animals to humans.
Researchers found that ethoxzolamide inhibits TB's ability to detect acidic environments, effectively blinding the bacterium and allowing the immune system to attack. This compound could help shorten treatment duration and slow the emergence of drug resistance in TB.
A new University of Virginia study confirms that Americans' conscious and unconscious biases against lesbian women and gay men are decreasing across all demographic groups. The study found that implicit bias decreased by 13% over seven years, while explicit bias decreased twice as much.
The American Geophysical Union awards top honors to journalists Andrew Revkin, Douglas Fox, and Sandi Doughton for their exceptional science reporting. Revkin receives the Robert C. Cowen Award for his climate change coverage, while Fox wins the Walter Sullivan Award for his story on dust's impact on drought in the US West.
A study published in Scientific Reports reveals that roosters follow a systematic rule based on social ranking to determine the order of crowing. Dominant birds take priority to announce the break of dawn, while subordinate birds wait patiently for their turn.
Researchers investigate granitic rocks in El Capitan using field mapping, rock climbing, and geochemical analyses. They found no systematic patterns in rock composition, challenging models of granite formation that rely on magma chambers.
The Global Precipitation Measurement satellite tracked Typhoon Halola's strengthening and intensification, revealing heavy rain rates of over 84 mm/h. The storm's tall thunderstorm towers reached heights of over 10.5 miles, releasing energy that can lead to intensification.
A new algorithm, DeMAND, is helping scientists identify the full repertoire of proteins affected by a drug. By analyzing gene expression changes and protein interactions, DeMAND provides a more comprehensive picture of a drug's effects.
A University of Delaware-led study found that an intensive regimen of regular exercise and a healthy diet can reduce the short-term onset of knee pain for overweight adults with Type 2 diabetes. The study, published in Arthritis Care and Research, shows a 15% decrease in knee pain development among those who underwent the intensive pro...
Researchers at Rice University have developed a new method to incorporate light-capturing nanomaterials into solar panels, increasing efficiency and reducing costs. This breakthrough could help meet the US goal of reducing solar electricity costs to 6 cents per kilowatt-hour.
New research reveals that gender faultlines can appear when individuals share demographic traits and professional interests, leading to a stronger sense of in-group identity among employees. The study found that such faultlines have a negative effect on employee loyalty, but a supportive diversity climate can mitigate this issue.
A team of researchers at Washington State University has discovered a novel structural function of the protein ATF5, which guides transcription and provides structure within the centrosome. This finding sheds light on the role of ATF5 in cell division and its potential implications for cancer growth and disease treatment.
Researchers at Washington State University found no accumulated glyphosate in human milk despite widespread use of Roundup herbicide. The study's results contradict a previous, unverified claim and provide strong evidence for the safety of breast milk.
A new Rutgers University study found that a hormone deficiency in the brain can lead to overeating and a preference for high-fat food. Researchers discovered that reducing glucagon-like peptide-1 (GLP-1) in the central nervous system caused mice to consume more calories and show an increased preference for high-fat foods.
A team of researchers has discovered that abrupt warming events played a key role in the mass extinction of megafauna during the last ice age. The study found that rapid warming, not sudden cold snaps, was the cause of extinctions among species such as mammoths and giant sloths.
University of Pennsylvania engineers have discovered a silicon-based photonic device sensitive to photon spin, enabling faster and more efficient computing. This breakthrough could lead to the development of photonic computers that exploit the spin of photons, potentially orders of magnitude faster than current technology.
A new online portal provides a robust online interactive database to address the 'antibody crisis' in molecular biology. The Histone Antibody Specificity Database allows scientists to find reliable antibodies for their research with higher confidence, using validated test results.
The new guideline provides a comprehensive framework for clinicians to manage gastrointestinal symptoms in children with autism spectrum disorders. It highlights the importance of nutrition management in addressing feeding and GI concerns, and recommends a standard manual of care for clinicians worldwide.
A new study from King's College London found that many of the same genes affect GCSE results in a range of subjects, including English, mathematics, science, and humanities. The research suggests that genetic factors explain over half of the differences between children's educational achievement across all disciplines.
Researchers found that men with low-risk prostate cancer are increasingly opting for active surveillance, while those with higher-risk tumors are receiving more aggressive treatments. This shift aims to reduce overtreatment and improve outcomes for patients.
Researchers developed an algorithm dubbed ENVE to detect genetic aberrations in tumors using deep sequencing data. The algorithm resolves most noise issues and reveals areas where genetic changes have gone awry, potentially leading to more effective treatments for multiple types of cancer.
A new study examined brain networks in veterans with trauma exposure using functional magnetic resonance imaging and graph theory tools. The researchers found that veterans with more severe PTSD re-experiencing symptoms showed weaker connectivity in two brain networks, including the hippocampus and prefrontal cortex.
Researchers are investigating the effects of endocrine disrupting chemicals on child behavior, memory, and learning. The four-year study aims to close a gap in research by examining thyroid hormone levels and their association with chemical exposure during pregnancy, infancy, or childhood.
Researchers identified the hectic emergency department environment and lack of baseline cognitive state as major barriers to delirium recognition. Doctors emphasized the need for a rapid screening test and a 'physician-proof' dementia screening tool to improve detection rates.
Research from The University of Manchester found that English people who upgrade their social status experience greater autonomy and control, leading to increased happiness. In contrast, Americans who rise in society's ranks are less satisfied than those who remain at lower levels.
Astronomers discovered jets of material ejected by still-forming young brown dwarfs, confirming they form through a scaled-down version of star formation. The presence of these jets was detected by the VLA and confirmed with Spitzer and Herschel space telescopes.
A study by University of Florida researchers found that body fat can send signals to the brain, affecting how it deals with stress and metabolism. The discovery reveals a novel fat-to-brain feedback network that was previously thought to be mainly driven by the brain.
A new study from Harvard T.H. Chan School of Public Health finds that over 70% of pollen and honey samples collected from foraging bees in Massachusetts contain neonicotinoids, a class of pesticide linked to Colony Collapse Disorder. The study suggests that these pesticides pose significant risks to bee health and human exposure.
A study by Dartmouth physicist Robyn Millan and NASA's Van Allen Probes has discovered new X-ray actions caused by solar flares, affecting Earth's atmosphere. The findings provide insight into the processes that can impact our lives directly.
Researchers at University of Birmingham discovered how mutated FLT3 genes reprogram blood stem cells, leading to abnormal cell production. The findings provide hope for developing new treatments for acute myeloid leukaemia.
A study published in Clinical Infectious Diseases found that 47% of grocery store-bought meat products contained Klebsiella bacteria, with many strains resistant to antibiotics. This increase poses a significant risk to human health, particularly for urinary and blood infections.
A new special issue in ecancermedicalscience explores the complex relationship between diet, metabolism, and cancer. Researchers investigate the role of antioxidants, obesity, and biomarkers in cancer development and prevention.
The discovery of Tetrapodophis amplectus, a four-legged snake fossil from Brazil's Crato Formation, supports the idea that snakes evolved from burrowing ancestors. The species' unique features, including short snout and flexible jaw, suggest it was adapted for grasping prey or clasp during mating.
Researchers found that genetically distinct cells in pregnant mothers, known as microchimeric cells, promote reproductive health and prevent pregnancy complications like prematurity and stillbirth. These cells help the immune system recognize and accept non-inherited maternal antigens, suppressing an immune system attack on the fetus.
Researchers have discovered a way to control magnetism using organic molecules, potentially leading to more efficient and cost-effective storage technologies. The study found that three molecular layers of phtalocynine can stabilize the magnetic orientation of cobalt surfaces, even in the presence of external magnetic fields or cooling.
Researchers found that stressed juvenile finches learn foraging skills exclusively from unrelated adult birds, ignoring their parents. This change may help avoid negative feedback loops and potentially more adaptive behaviors.
Researchers at Beth Israel Deaconess Medical Center found that endovascular aortic repair provides better outcomes, including lower mortality rates and shorter hospital stays, compared to open surgical repair. The study shows improved long-term results over time, with benefits extending up to eight years after surgery.
A 30-year longitudinal study shows that frequent social interactions at age 20 and quality relationships at age 30 are beneficial for well-being later in life. Meaningful social engagement starts having its greatest impact at age 30, but is also beneficial at any age.
Proteins in the Wnt signaling pathway play a critical role in driving kidney scarring, which can lead to chronic kidney disease. Boosting expression of Wnt proteins in healthy kidneys may be an effective strategy for treating chronic kidney disease.
A multi-institutional research team discovered that early animals took their first breaths with only a slight increase in oxygen levels, contradicting the long-held theory of dramatic oxygen changes. This finding provides new insights into the evolution of complex life forms like whales and sharks.
A University of Michigan study found that teens using marijuana for medical reasons are 10 times more likely to say they're addicted than those who use it illegally. The study highlights the need for improved medical marijuana policies to address teen addiction.
A UTHealth researcher has been awarded a grant to analyze the genetic and social network aspects of HIV transmission clusters. The study, led by Dr. Kayo Fujimoto, will compare social clustering by venue to common viral strains of HIV infection.
Researchers at Ben-Gurion University have developed a new one-step graphene production process that is faster and potentially scalable. The lamp-ablation method produces high-yield few-layer graphene without toxic substances.
A study published in PLOS Pathogens found that older individuals are more susceptible to West Nile virus due to impaired immune responses. The researchers discovered that older mice had delayed antibody responses, reduced helper T cells, and lower chemokine levels, leading to higher viral loads and increased brain damage.
A team of engineers and doctors at Vanderbilt University has developed a surgical robot with steerable needles equipped with wrists that provide needlescopic tools with previously lacked dexterity. This innovation allows for precise resections, suturing, and access to areas such as the nose, throat, ears, and brain.
Researchers at Cardiff University have identified a critical function of the DISC-1 gene that plays a crucial role in brain development and plasticity. The study reveals a vulnerable period in early brain development where failure to bind with specific molecules leads to irreversible effects on later-life plasticity.
Leading cancer experts recommend several measures to reduce high cancer drug prices, including a post-approval price review mechanism and Medicare negotiations. The recommendations aim to improve patient care and alleviate the financial burden on those affected by high cancer drug costs.
A study found that additional radiation to lymph nodes reduces breast cancer recurrence, but does not increase overall survival. The treatment was associated with limited toxicity and is recommended for women with axillary node-positive or high-risk node-negative breast cancer.
Researchers found that people with schizophrenia experience relational encoding problems and regional brain dysfunction in the dorsolateral prefrontal cortex and hippocampus. The study suggests a new target area for treatment development to improve memory in individuals with psychosis.
Researchers at Cornell Food & Brand Lab created a Grocery Retailer Scorecard to encourage healthy shopping practices. The scorecard helps shoppers rate their favorite store's healthiness, promoting the sale of perishable items like fruits and vegetables.
A new study from Florida Tech suggests that well-managed coral reefs in the Pacific Ocean can keep up with sea-level rise through vertical growth, but only if carbon dioxide levels stay below 670 parts-per million. If emissions exceed this threshold, even healthy reefs will struggle to adapt.