Researchers at UT Austin found a surprising link between cross-shaped DNA structures and human cancer, with small cruciforms enabling mutations that increase cancer risk. High-performance computing helped identify hotspots of genetic instability in cancer genomes.
A study by Moffitt Cancer Center researchers highlights the need for stress management tools for Latina women undergoing chemotherapy for breast cancer. Despite facing significant stress-inducing factors, many patients reported a lack of access to these resources.
Researchers at INRS have successfully guided electric discharges using lasers, achieving smooth paths along straight or parabolic trajectories. The study's findings hold significant potential for various applications, including combustion engines and pollution control.
The Alberta Cancer Exercise (ACE) pilot study explores a community-based approach to support cancer survivors in regaining their strength and energy levels. Participants receive either standard care or supervised group exercise training, showing promising results for improved physical fitness and mental well-being.
Researchers at St. Jude Children's Research Hospital have found a way to prevent or slow progression of colorectal cancer by boosting the activity of a protective gene called AIM2 and giving patients healthy donor bacteria.
A genetic mutation in the TEAD1 gene has been identified as the first associated with Aicardi syndrome, a debilitating childhood neurological condition. The study found that children with this disorder experience severe symptoms, including seizures, retina damage, and brain abnormalities, and that boys may also be affected.
A recent study found that 34% of participants had moderate or severe sleep-disordered breathing, and 31% experienced short sleep duration. Racial/ethnic minorities were more likely to have undiagnosed sleep apnea and poor sleep quality compared to whites.
Researchers developed an ultra-superovulation method to increase the number of eggs obtained from genetically modified mice, reducing the need for multiple females and improving efficiency in IVF and embryo transfers. The breakthrough could lead to a significant reduction in the number of experimental animals used in research.
NASA's Aqua satellite captured a visible image of Tropical Depression Bill's remnants over the central United States on June 18. The storm is expected to bring significant rainfall and flash flooding to the eastern two-thirds of the US, including sections of Arkansas, Missouri, Illinois, Indiana, Ohio, Louisiana, and Texas.
Research comparing traditional hunter-gatherer communities with and without access to electricity reveals that those with electricity sleep an average of one hour less per night than those without. The study suggests that artificial light disrupts humans' natural circadian clock and sleep-wake cycle, leading to shorter nights.
The study analyzes 100,000 Californians' health records and genetic data to track down genetic contributions to disease. Researchers have identified genetic variants linked to various diseases, including prostate cancer, allergies, and diabetes.
A Boston University School of Medicine researcher has been awarded a four-year, $1.6 million NIH grant to investigate how immunity to pneumonia develops and protects certain individuals. The study aims to understand the role of resident memory T cells in preventing pneumonia and identify who is most likely to get the disease.
Researchers found that increased levels of fibronectin create a protective environment reducing the effectiveness of BRAF inhibitors. Targeting both tumor cells and their adaptive responses is crucial for improved therapeutic outcomes.
Researchers at Johns Hopkins Medicine identified a potent seizure inhibitor in mice using D-leucine, an amino acid found in many foods and certain bacteria. The amino acid interrupts prolonged seizures effectively without sedative side effects, paving the way for new treatments for drug-resistant epilepsy.
A California lake fire has burned over 11,000 acres in the San Bernardino National Forest, with 150 structures threatened. The fire's proximity to hiking trails and high-pressure weather conditions are hindering containment efforts.
A new study by University of Michigan graduate research fellow Micaela Martinez-Bakker reveals that silent transmission of poliovirus could continue for more than three years with no reported cases. To ensure eradication, aggressive surveillance programs and vaccination campaigns must continue in endemic countries.
Engineers have created a prototype for real-time listeria bacterial contamination detection, aiming to detect levels as low as one bacteria in a 25-gram sample. The device utilizes nanobrushes that select and capture specific bacteria, mimicking the mechanism used by the Hawaiian bobtail squid's cilia.
Researchers at OIST developed a method to recreate connections between neurons from two different brain areas in a dish, allowing for the study of brain function and potential treatments for neurological disorders. The breakthrough used neurons from embryos of mice and created a working corticostriatal network.
Research found that children with strong verbal working memory skills can more effectively cover up lies, while those with weaker verbal memory struggle. This link suggests that verbal working memory plays a crucial role in lying.
Researchers found modest improvements in patients with spinal cord injury treated with olfactory mucosa transplants, showing 'promising and safe' results. The study demonstrated benefits in ASIA sensory scores, bladder compliance, sensation, and daily life activities.
Researchers at EMBL Heidelberg solved a decades-old cell biology puzzle by clarifying the behavior of clathrin proteins, crucial for endocytosis. The team used new imaging techniques to demonstrate that the surface area of the clathrin coat remains constant during endocytosis, only changing its curvature as it draws the cell membrane i...
A new study confirms that humans are causing a rapid pace of species loss, with extinction rates up to 100 times faster than normal, threatening ecosystem services and human survival. The researchers warn that inaction will lead to irreversible damage, but call for urgent conservation efforts to avoid a sixth mass extinction event.
Researchers at University of California, San Diego School of Medicine have identified a biological marker for mental illness in female patients. The study found that specific genes, including XIST, are over-produced in women with mental illnesses like bipolar disorder, major depression, and schizophrenia.
A study found that over half of seniors injured in motor vehicle crashes were still taking pain medication six months later. The results highlighted the need for effective management of acute pain in older adults to prevent negative consequences on function and quality of life.
Former hurricane Carlos has dissipated, bringing an end to its eastern Pacific journey. The National Hurricane Center reported no areas of suspect development for the next couple of days.
Astronomers using ALMA measured the mass of a supermassive black hole at the center of NGC 1097, a barred spiral galaxy 45 million light-years away. The black hole was found to be 140 million times more massive than our Sun.
A study from the University of Rochester found that stress in low-income families can affect children's learning. Children with family instability or harsh caregivers had elevated or low cortisol levels, leading to lower cognitive ability at age 4.
Researchers used genetic tools to trace illegal ivory back to its source, identifying two primary poaching hotspots in Africa since 2006. The study found that most savanna and forest elephant tusks originated from Tanzania, Mozambique, Gabon, and the Central African Republic.
A new study by USC's Valter Longo suggests that a periodic diet mimicking fasting can cut visceral belly fat, boost neural regeneration and improve learning and memory in old mice. In humans, the pilot study found evidence of reduced risk factors for aging, diabetes, cardiovascular disease and cancer with no major adverse side effects.
Researchers are using alternative breeding methods to increase switchgrass's biomass yield, ethanol production, and reduce lignin content. The study utilizes the Smith-Hazel Selection Index to select for multiple traits simultaneously, aiming to speed up the breeding process and achieve more ideal switchgrass by 2025.
A study published in PLOS ONE found that the Hawaiian hoary bat migrated to Hawaii from the Pacific coast of North America in two separate waves over 9,000 years apart. This genetic history suggests that the current legal protection may be inadequate or misdirected, highlighting the need for updated conservation efforts.
Researchers find striking similarities between snake fungal disease and white-nose syndrome in bats, both persisting across habitats and infecting multiple species. The snake fungus, Ophidiomyces ophiodiicola, is highly virulent and can spread through pet trade and animal release.
Researchers found that three- and five-year-old children are just as likely to respond to the needs of another individual as they are to their own. This suggests a core component of a sense of justice based on empathy, which is central to human prosociality and punishment.
The Community for Open Antimicrobial Drug Discovery aims to screen over 50,000 chemical compounds in the next 18 months to combat superbug-resistant bacteria, with the goal of preventing millions of deaths by 2050.
A study published in JNCI found that women with tubal ligation who develop aggressive endometrial cancer types have lower mortality rates. The researchers suggest that TL reduces cancer cell passage through the fallopian tubes, lowering disease stage and mortality.
A special issue of Future Oncology explores the role of biomarkers and next-generation sequencing in advancing cancer research and treatment. The issue highlights the potential of these technologies to provide a more precise picture of cancer and identify effective treatments.
A recent study has provided a more complete picture of how proteins move, laying the foundation for understanding molecular causes of human disease and developing potent drug treatments.
Scientists have discovered transient spikes in temperature at several spots on Venus' surface, indicating active flows of lava. The hotspots are clustered in a large rift zone called Ganiki Chasma, suggesting ongoing volcanic activity.
Researchers uncover hidden diversity in minute midges through DNA analysis and type material examination. Two new species were discovered and one misidentified species was corrected, shedding light on the fascinating world of non-biting midges.
Researchers have used ultra-short pulses of X-rays to create a film of shock waves in diamonds, providing new insights into the structure of these hard materials. The study reveals that intense shock waves can compress diamond by almost ten percent, opening up new perspectives on its dynamic behavior under high pressure.
A team of University of Iowa researchers analyzed over 200 YouTube videos to understand toddler tablet use. They found that by age two, most children can moderate their ability to use a tablet, while younger toddlers require more guidance.
A small audit of clinical practice found that doctors often misdiagnose zinc deficiency and are unaware of the impact of excess zinc on the body. High doses of zinc supplements can disrupt copper uptake, leading to anaemia and neurological symptoms.
A new mass spectrometry-based technology enables rapid analysis of tissue samples, offering a faster and more accurate alternative to traditional methods. The automated droplet-based surface sampling probe reduces testing time for cancer diagnosis from 20-30 minutes to just 4-5 minutes.
Professor Tiago H. Falk has received the Canadian Medical and Biological Engineering Society Early Career Achievement Award for his innovative research projects in biomedical engineering and multimedia communications. His work includes assistive devices for people with disabilities and low-cost methods for diagnosing Alzheimer's disease.
A systematic review found that sedentary behavior is associated with an increased risk of anxiety in adults and children. The link may be due to disturbances in sleep patterns, social withdrawal theory, and poor metabolic health. Further research is needed to confirm the causal relationship between sedentary behavior and anxiety.
A study published in Environmental Research Letters suggests that climate change will not significantly reduce winter deaths. The research found that cities with warmer winters have similar amounts of winter deaths as those with colder winters, likely due to the prevalence of flu and respiratory diseases rather than cold-related causes.
Researchers at UCLA have created a novel system that can store solar energy for several weeks, unlike current systems which only hold energy for a few microseconds. The breakthrough design is inspired by photosynthesis and uses polymer donors and nano-scale fullerene acceptors to separate charges.
In a study published in Nature Medicine, researchers found that disabling the production of NETs (neutrophil extracellular traps) can speed up wound healing in diabetic mice. By preventing neutrophils from producing NETs, wounds healed more quickly and tissue repair was improved.
WSU scientists demonstrate that resveratrol converts excess white fat into beige fat, reducing weight gain by 40%. Polyphenols found in fruit enhance fat oxidation, preventing obesity and metabolic dysfunction. Increasing fruit consumption can boost total polyphenolic intake.
Researchers found that six-gill and prickly deep-sea sharks are positively buoyant, requiring less energy to swim upward than downward. This adaptation may provide them with a 'stealth' advantage during hunting or aid in nightly migrations to shallower areas.
Korean scientists have successfully created a new class of radical compounds by reacting nitric oxide with N-heterocyclic carbenes. The resulting nitric oxide compounds show potential for targeted NO delivery, which could lead to new therapeutic applications in various human diseases.
Astronomers use Hubble Space Telescope to uncover the early formative years of quasars, finding that galaxy collisions and mergers drive their peak activity. The observations reveal the transitional phase in the merger-driven black hole scenario, providing new insights into the universe's brightest objects.
Researchers developed a novel live-imaging system to study gene transcription and nuclear position, enabling simultaneous measurements of these processes. The technique shows high specificity and has potential applications in studying higher-order gene regulation and cell-to-cell heterogeneity.
Researchers from UNC School of Medicine provide direct experimental evidence for the rapid synthesis of two classes of proteins necessary to create life on Earth. They found that a single ancient gene probably used its two opposite strands of DNA to code for different catalysts that both activated amino acids.
A new study uses massively parallel gene function assays to characterize nearly 2000 BRCA1 variants, providing a potential solution for sorting out harmful and harmless variants. The approach demonstrates promise but is not yet ready for use in the clinic.
Researchers found that musicians' brains can incorporate abstract music notation to enhance their visual perception of congruent musical notes. Non-musicians showed no significant difference in visual preference regardless of the melody played.
Researchers predict and synthesize five new calcium carbides with varied chemical and physical properties, including a two-dimensional metal-like compound. The discovery opens up possibilities for industrial applications in the chemical industry.
Researchers developed a calorie-restricted diet that mimics fasting to promote regeneration and extend lifespan in mice. A human pilot study found similar benefits, with decreased risk factors for aging-related diseases.
Two new studies shed light on the Himalayan tectonic system, confirming a strike-slip dominated fault in western Nepal and highlighting topographic and tectonic discontinuities. The findings also support the initiation of mountain belt-parallel extension in the mid-Miocene epoch.
A decade-long investigation by Wayne State University and Children's Hospital of Michigan researchers identified a key gene mutation that can trigger acute lymphoblastic leukemia. The mutation affects ETV6, a gene that regulates growth rates in bone marrow, leading to an increased risk of blood cancer.