A new study found that people with depression release less of a natural pain and stress-reducing chemical called natural opioids when rejected, prolonging the pain of social rejection. In contrast, they experience relatively better feelings when someone they're interested in likes them back, but only momentarily.
Researchers studied plain wrens' precise phrase-by-phrase modifications to achieve careful coordination in their duets. The study found that females perform longer intervals when their mates don't answer, and males modify intervals based on both the phrase type sung and the female's response.
A study by Spanish scientists confirms that exposure to persistent organic pollutants in the body is linked to higher levels of cholesterol, triglycerides, and obesity. The researchers analyzed nearly 300 men and women and found a correlation between pollutant levels and health risks.
Hospitals participating in ACS NSQIP improve surgical outcomes, including reduced death rates, complications, and surgical site infections. Over time, these improvements continue to accumulate, enabling hospitals to prevent significant patient harm.
A new study by University of Vermont neurologist Andrew Solomon and colleagues reports that MS patients want to know the details of their physicians' financial relationships with pharmaceutical companies. The study found that disclosure of these relationships can influence patients' decisions to participate in clinical trials.
The NIH/National Institute of Allergy and Infectious Diseases has launched a clinical trial to test the safety and efficacy of ZMapp, an experimental Ebola treatment. The study will enroll adults and children with known Ebola infection and compare the treatment to standard care.
Researchers at KU Leuven developed a simple and effective way to untangle DNA using a 'rolling droplet' technique. The method involves injecting genetic material into a droplet of water and dragging it over a glass plate covered with a sticky polymer, resulting in longer and straighter DNA strands that can be studied under a microscope.
Columbia University researchers successfully converted human skin cells into hypothalamic neurons, a type that regulates appetite. These neurons provide a patient-specific model for studying the neurophysiology of weight control and testing potential therapies.
A new UT Arlington study finds that employees who receive electronic correspondence from work after hours become angry more often than not, interfering with their personal lives. The researchers identified two categories of workers: segmentors who separate work and personal life, and integrators who want to stay connected with work.
A study published in JAMA Oncology found that 10% of CLL patients discontinued ibrutinib therapy due to disease progression. Patients who experienced Richter's transformation or progressive CLL had poorer outcomes and required alternative therapy quickly after discontinuation.
Researchers at the Montreal Neurological Institute and Hospital have discovered a new mechanism driving cancer cell metastasis, focusing attention on the biological role of DENND2B protein. The study highlights Rab13 as an enzyme promoting cell migration in cancer cells.
University of Utah engineers create a filter for separating different frequencies in the terahertz spectrum, a key step towards utilizing this bandwidth for commercial use. The filter can be fabricated using an off-the-shelf inkjet printer and has the potential to boost data transmission rates by thousands of times.
A unique combination of ecological, environmental, and behavioral factors led to the abundant production and preservation of Early Triassic swim tracks. Delayed ecologic recovery, depositional environments, and tetrapod swimming behavior contributed to their formation.
Scientists developed a mathematical law for pedestrian interactions based on time until collision, revealing consistent patterns in crowd behavior. The model can be used to predict potential dangers in sporting events and festivals, as well as improve public space design.
Researchers found that patients who received chemotherapy after bladder cancer surgery had improved overall survival rates compared to those who underwent surgery alone. The study analyzed over 5,600 patients and demonstrated a significant reduction in mortality risk.
Researchers are advancing blood biomarker capabilities using the Simoa technology, which offers unprecedented improvement in sensitivity proteins for detecting traumatic brain injury. The technology allows for more effective measurement of low concentrations of proteins such as tau, enabling more accurate diagnosis and treatment.
A new model developed by Iñigo de la Parra simulates power fluctuations in large grids of photovoltaic power stations, enabling operators to optimize energy efficiency and reduce costs. The model helps to comply with grid codes and provides a solution for companies setting up large-scale photovoltaic plants.
Scientists capture first detailed images of ultra-small bacteria, average volume of 0.009 cubic microns, with unique internal structure and metabolism. The discovery sheds light on the role of microbes in climate, food and water supply, and ecosystems.
A recent study published in the IBD Journal found significant racial disparities in the treatment and outcomes of children with Crohn's disease. Black children had a 1.5 times higher frequency of hospital readmissions due to Crohn's disease compared to white children.
Research reveals spatial clusters of personality traits within cities, states, and countries, with associations between life satisfaction, terrain preference, and self-esteem. Studies also explore the role of geography in shaping individual behavior and well-being.
Scientists at the Gladstone Institutes found that HIV remains active as infected cells transition to rest, controlled by the virus's Tat protein. This independent control allows the virus to survive even if host cells are inactive, making it harder to cure the infection.
Suicide rates among US adults aged 40-64 have increased by 40% since 1999, with a sharp rise since 2007. Economic factors such as job loss, bankruptcy, and foreclosure are being identified as contributing to this trend.
Researchers developed a new test analyzing 'immune hotspots' to predict breast cancer survival. The test uses statistical software to track the immune system's reaction to tumors, identifying those who need intensive treatment.
Tropical Cyclone Glenda is being stretched out by wind shear over the Southern Indian Ocean, according to NASA's Terra satellite imagery. The storm's maximum sustained winds have dropped to near 45 knots as it moves south at 7 knots.
Researchers use statistical mechanics to model a zombie outbreak, finding that cities fall quickly but less populated areas take weeks to infect. The ideal hideout is the northern Rockies, where survivors can prepare for months before zombies reach.
Researchers identified distinct immune changes in patients with chronic fatigue syndrome (ME/CFS), providing robust physical evidence of the disease's biological nature. The study's findings could improve diagnosis and treatment options for the debilitating disorder.
Disney Research develops a new platform to automate aspects of authoring interactive narratives, allowing users more control over storylines and resolving narrative inconsistencies. The IBTs enable authors to create free-form experiences with multiple story arcs.
Researchers at the University of Manchester and DSM have developed a single-step method for producing pravastatin, a widely used cholesterol-lowering drug. This breakthrough reduces the cost and complexity of statin production through reprogramming of the Penicillium chrysogenum fungus.
Researchers have created a new method to monitor the effect of anti-cancer drugs on rare leukaemia stem cells, enabling personalized treatment and potential cure. The approach involves testing small samples of cells with a novel technology platform.
The Curiosity robot has confirmed an episodic increase in methane concentration in Mars' atmosphere, which may indicate the presence of biological activity. The detection is based on detailed analysis of data collected during 605 Martian days and is attributed to the tunable laser spectrometer in the SAM instrument.
The Anderson Algorithm increases surgical success in advanced ovarian cancer by providing a personalized approach to surgery, resulting in high complete resection rates of over 86%. This milestone is strongly tied to improved survival outcomes for patients.
Researchers at Cornell University have modeled a methane-based, oxygen-free life form that can metabolize and reproduce like life on Earth. The theorized cell membrane, called an azotosome, is composed of small organic nitrogen compounds and shows stability and flexibility similar to Earth's phospholipid membranes.
Researchers applied an electric field to a section of the Keystone pipeline, smoothing oil flow and reducing pump energy savings. The Applied Oil Technology (AOT) device produced significant reductions in viscosity and turbulence, leading to a 75% decrease in pump power from 2.8 megawatts to 0.7 megawatts.
Research from the University of Waterloo suggests that intimate partners with low self-esteem resist addressing problems, fearing rejection and negative outcomes. This can lead to greater overall dissatisfaction in the relationship.
Researchers have discovered a neuroprotective compound that limits brain damage during ischemia associated with stroke and other brain injuries while minimizing side effects. The pH-dependent NMDA receptor antagonist, 93-31, reduces damaged brain tissue by over half in mouse models.
A recent study found that new mothers experiencing higher social stressors have a 2.5 times higher odds of having only partial or no restrictions on smoking in their home, exposing infants to secondhand smoke. The researchers identified statistically significant socio-demographic and socio-economic trends in home smoking rules, highlig...
Researchers have developed a new method to protect computer chips using advanced 3D optical imaging and photon encryption, making them virtually uncounterfeitable. The system replaces traditional electronic part numbers with compressed QR codes that can be scaled down to the size of microns.
The Association for Gerontology in Higher Education (AGHE) recognizes excellence in gerontological education and training. The recent award recipients include Suzanne R. Kunkel, Jennifer C. Mendez, Dena Shenk, Eleanor Krassen Covan, Feliciano Villar, Montserrat Celdran, Josep Fabà, Graham D. Rowles, Katherine Humber, Tina Kruger Newsha...
A new species of algae has been found in reef corals of the Persian Gulf, enabling them to survive in extremely high temperatures. This discovery provides hope for coral reefs to adapt to climate change, but also highlights other threats such as pollution and nutrient enrichment.
Researchers estimate that up to 20% of people aged 50-60 and more than 70% of people over 90 have blood cells with the same gene changes as found in leukemia. Genetic mutations associated with leukaemia become inevitable with age, increasing dramatically with age.
Researchers at the University of Washington argue that environmental conservation requires adapting to an uncertain future. They suggest creating flexible policies with legs, supporting ecosystem diversity, investing in monitoring, expecting unexpected changes, and designing adaptive management strategies.
Cancer data in sub-Saharan Africa is being questioned due to its poor population coverage and weak registration systems. GLOBOCAN statistics are heavily relied upon by Governments and NGOs, despite lacking independent evaluation. Experts call for improved cancer registration systems and more transparency from the WHO.
Tropical Cyclone Glenda is intensifying with powerful thunderstorms and a hint of an eye forming in its center. It is expected to strengthen and then transition into an extra-tropical storm due to favorable upper-level conditions.
Researchers discovered a new cellular factor critical to Ebola virus infection and identified Tetrandrine as a potent small molecule inhibiting the virus's entry into human white blood cells. The compound showed efficacy in preventing Ebola virus disease in mice without obvious side effects.
Researchers use RNA interference to target essential genes in the beetle, resulting in a 100% mortality rate after five days of feeding. This technology offers precise protection without chemicals and foreign proteins production, making it a promising strategy for pest control.
Human antibodies have been isolated and characterized that can neutralize the Marburg virus, a close cousin to Ebola. The discovery could lead to the development of an effective treatment and vaccine against these often lethal viruses. Researchers hope to complete clinical safety trials by the end of the year.
Researchers studied mantis shrimp claws, discovering that certain parts are more sensitive to changes than others. This mechanical sensitivity allowed the other parts to evolve independently without compromising the striking force.
A Scripps Research Institute team has discovered an antibody that can target both Marburg and Ebola viruses, paving the way for new treatment options. The antibody works by binding to a vulnerable site on the virus's surface, preventing it from entering human cells.
Researchers identify small molecules that program stem cells to target specific areas in the body. These compounds enable targeted delivery of stem cells to diseased or damaged tissue, reducing inflammation.
A recent study by Penn State researchers found that children of undocumented Mexican immigrants have a significantly higher risk of internalizing and externalizing behavior problems compared to their co-ethnic counterparts with documented or naturalized citizen mothers. The study used data from over 2,500 children ages three to 17 in L...
A new cancer drug called PAC-1, which targets cancer cells by restoring an enzyme's activity, is now entering phase I clinical trials in humans. The drug was first tested in pet dogs with spontaneously occurring cancers and showed promising results.
Jon Schuller, UCSB assistant professor of electrical and computer engineering, is studying how light interacts with complex materials like plastics, which have unique optical properties. The research could lead to the development of new organic photonic devices with enhanced performance and low-cost semiconductors.
Researchers at Instituto Gulbenkian de Ciencia discovered that proteins controlling cellular rigidity can induce the activation of factors promoting tumor growth. The study found that changes in the cell's skeleton dynamics lead to rearrangements in filaments, resulting in faster cell proliferation and tissue overgrowth.
A study published in JAMA Oncology found that patients with advanced cancer perceived a higher level of compassion from physicians when presented with an optimistically framed message about future treatment options. The results suggest the need for extra support and care for delivering bad news while preserving hope.
Researchers at NYU Langone Medical Center discovered that the specialized DNA-binding protein CTCF is essential for precise gene expression in developing embryos. The findings shed light on how Hox genes maintain cellular positioning and position-specific gene regulation.
Researchers have identified two urinary biomarkers that can predict bladder cancer-specific survival and guide treatment. The study validated the biomarkers in over 400 clinical samples, showing they are independent predictors of cancer prognosis.
Research found that GLP-1 secretion is lower among people with pre-diabetes and obesity compared to normal weight individuals. The study suggests that early intervention with GLP-1 analogues may postpone the onset of type 2 diabetes.
A new study reveals that children of undocumented Mexican immigrants are more likely to experience internalizing and externalizing behavior problems, such as sadness and aggressiveness. The researchers rule out explanations based on socioeconomic status or maternal mental health, highlighting the need for culturally-sensitive services.
Researchers found that male mosquitoes' reproductive traits evolved with their capacity to transmit malaria, leading to new targets for control. The study reveals key factors driving mosquito ability to spread the Plasmodium parasite.
A new oral, controlled-release form of DNP, known as CRMP, reversed fatty liver, insulin resistance, and hyperglycemia in rat models of NAFLD and type 2 diabetes, with no adverse effects. The therapy achieved plasma concentrations that were more than a 100-fold less than the toxic threshold.