Researchers have made breakthrough discoveries in understanding Pelizaeus Merzbacher disease (PMD), a devastating neurological condition. The study found that myelin-producing cells are still active and can be stimulated to produce more myelin, potentially leading to new treatments for PMD and multiple sclerosis patients.
The Interprofessional Oral Health Grant Team at NYU College of Nursing introduces the HEENOT approach, a comprehensive examination that includes oral cavity assessment. This method is expected to increase interprofessional oral health workforce capacity and improve oral-systemic health across the lifespan.
Research explores how gut bacteria influence brain activity, sleep, stress responses, and disease development. The human microbiome's role in brain function is a growing area of study, with potential therapeutic applications through dietary modification.
Scientists at UC San Diego School of Medicine discovered that enzymes believed to promote cancer actually suppress tumors. Correcting a loss-of-function PKC mutation in colon cancer cells reduced tumor growth in mouse models, demonstrating normal PKC activity inhibits cancer.
A team of researchers identified a key epigenetic factor EZH2 that plays a central role in controlling tumor growth and metastasis in melanoma. The study found that suppressing EZH2 activity can prevent the growth and spread of cancer cells, offering new hope for cancer treatment.
A Northwestern University study found that family members sharing familiar stories with coma patients who wore headphones recovered consciousness faster and had improved outcomes. This 'familiar auditory sensory training' stimulated the brain's memory circuits, helping patients wake up more easily and respond to their environment.
Early human ancestors, such as Australopithecus africanus, used human-like hand postures for forceful precision and power gripping 3-2 million years ago. This discovery supports archaeological evidence for stone tool use among fossil australopiths.
Researchers discovered that an anti-inflammatory protein can increase plaque formation in the brain by binding to amyloid-beta and accelerating its buildup. The study suggests that Alzheimer's treatment should be tailored to patients carrying specific APOE variants, such as APOE4, which is a major genetic risk factor for the disease.
A recent study found that communities with higher levels of Indigenous language knowledge and cultural continuity have significantly lower diabetes rates, contrary to expectations. The research suggests that reconnecting Aboriginal Canadians to their cultural roots may be a crucial factor in addressing the epidemic of modern times.
Researchers use laser-driven compression to study extreme conditions inside planets, revealing properties of silica that determine planet formation and evolution. The findings suggest large rocky planets may have long-lived oceans at depth and could explain the existence of planets like Neptune and Uranus.
Researchers at Children's Hospital Los Angeles found that neonatal mouse hearts can fully recover normal function after mild injury but fail to regenerate after severe injury. The study suggests that cardiac regeneration strategies should be tailored to the type and severity of heart injury.
Researchers found that autophagy, a cellular recycling process, helps eliminate a molecule called A20 that blocks the immune response. By removing A20, autophagy allows for a quick release of emergency signals, boosting anti-fungal immunity.
Researchers investigated Ebola's deadly nature, discovering that genetic changes enable the virus to become more severe with each transmission. The study sheds light on the evolutionary goal of Ebola virus to become more lethal, informing future treatment strategies.
Researchers have identified a new bacterial communication pathway, dialkylresorcinol, that is widely distributed among pathogenic bacteria. This discovery offers a promising therapeutic target for new medicines, potentially reducing the risk of antibiotic resistance.
A recent study by Robert Mai and Stefan Hoffmann found that healthy food is often perceived as tasting bad, leading to overconsumption of unhealthy options. Despite education on ingredients, consumers prioritize taste over healthiness, making it challenging to combat obesity rates.
A USC study reveals that the brain's protective blood barrier becomes leaky with age, starting at the hippocampus, a critical learning and memory center. The findings suggest that brain scans may be able to detect changes in blood vessels before they cause irreversible damage leading to dementia.
Only about half of teenage girls receive the HPV vaccine at the recommended age of 11-12, leaving them unprotected against cervical cancer and genital warts. Researchers found that rates of HPV infection increase significantly among young people between 14-24, emphasizing the importance of early vaccination.
A new study in Journal of Consumer Research reveals that buying products to compensate for perceived shortcomings can lead to increased focus on failures. Researchers found that such 'compensatory consumption' impairs self-control and undermines mental resources.
A new study finds that black-and-white images lead consumers to focus on essential product features, whereas colorful images draw attention to less important aspects. This allows companies to promote primary features with black-and-white ads and secondary features with color ads.
Researchers combined traditional ecological knowledge and scientific methods to identify forest conditions preferred by beargrass harvesters. Key findings include differences in coarse woody debris, tree density, and beargrass leaf color between 'good' and 'poor' sites.
Researchers at MIT developed an algorithm to optimize optimization algorithms, guaranteeing the best possible solution for complex engineering problems. By using a Gaussian smoothing technique, they generate a sequence of simpler problems that progressively add complexity, ensuring convergence to a global minimum.
In a study published in Nature, NYU researchers found that emotional learning can strengthen older memories by selectively preserving previously insignificant information. Participants were shown images of animals and tools, with some receiving shocks to make certain categories emotionally meaningful. Memory for these images was better...
A recent study revealed that the Nigeria-Cameroon Chimpanzee subspecies has a more complex evolutionary history than previously thought, with three distinct populations found in central Cameroon. The research also suggests that climate change could cause significant harm to chimpanzee populations due to habitat alterations.
A new report reveals that H7 influenza viruses regularly shuffle combinations of genetic segments, each with its own history of travel among hosts and geographic places. The study uses genomic analysis to visualize the spread of H7 genes across vast distances, identifying transboundary and transcontinental transmission.
Scientists have made new discoveries about Antarctica's geology and biology using a hot-water drill and an underwater robotic vehicle. The expedition uncovered a unique ecosystem of fish and invertebrates living in an estuary deep beneath the Antarctic ice.
NASA's Global Precipitation Measurement mission combined with satellite data revealed an area of maximum rainfall centered over Samar, resulting in extreme totals greater than 600mm. The analysis also found that much of the heavy rainfall from Mekkhala fell over the same area devastated by Super Typhoon Haiyan in 2013.
Researchers successfully mapped the condensation of individual atoms in microscopic measuring beakers, known as quantum wells. This breakthrough provides key conclusions on the nature of atomic bonding and enables the study of other atoms and their interactions.
Scientists developed a smart keyboard that senses typing patterns to distinguish individual users, providing an additional layer of security for computer systems. The device harnesses energy from typing to power itself or other devices, while its surface coating repels dirt and grime.
Researchers produced method protecting animal models from Syngap1 gene mutation effects, disrupting memory and anxiety levels. Early developmental period critical for treatment of psychiatric disorders caused by damaging Syngap1 mutations.
The Air Force Office of Scientific Research has awarded approximately $16.6 million in grants to 57 young investigators from research institutions across the US. The recipients will conduct basic research in areas such as dynamical systems, quantum processes, and energy, with a focus on advancing the Air Force mission.
INRS researchers will conduct innovative research in environmental equity, reproductive toxicology and infection treatment with new equipment. The lab will focus on noise and air pollution concentration, public services for vulnerable populations and prevention of male infertility.
A new study found that teen girls who practiced saying 'no' to unwanted advances in a virtual environment reported less sexual victimization. The effects persisted over three months, with those who previously experienced dating violence showing lower levels of psychological aggression and distress.
Environmental scientists use next-generation sequencing to track population adaptations to climate change, finding gene variants and altered expression that point to selection for climate-adapted traits. However, funding constraints may hinder the technology's adoption in ecological studies.
A new study found that teenagers with brothers and sisters who display no symptoms of antisocial behavior also struggle to recognize certain emotions. This impaired emotion recognition may be a factor contributing to the increased risk of developing conduct disorder in these individuals.
A Cornell University study reveals that surface meltwater can fill subglacial lakes beneath the ice sheet, providing heat to its bottom. This process could accelerate ice flow and alter the Greenland Ice Sheet's response to climate change.
Researchers propose that the Milky Way galaxy may contain a space-time tunnel, also known as a wormhole, which could be navigable. The study combined dark matter maps with general relativity equations to suggest this possibility.
Scientists found that oranges are packed with nutrients like carotenoids and flavonoids, which can help lower cancer risk and cardiovascular disease. However, juicing oranges may slightly lower nutrient levels but significantly improve their bioaccessibility.
Researchers at UCSD have identified a specific region of the alpha-synuclein protein where mutations can lead to the creation of ring oligomers, causing cell death. This discovery could lead to the development of compounds that target this region to prevent or treat Parkinson's disease.
Researchers from the University of Southampton have developed a new technique for generating more powerful and efficient pulsed lasers. The technique uses coherent combination of multiple semiconductor lasers, allowing for complex pulse waveforms with user flexibility.
A study published in JAMA Surgery found that nonsteroidal anti-inflammatory drug (NSAID) use is associated with a higher risk of anastomotic leaks after nonelective colorectal procedures. The study included over 13,000 patients and showed a 24% increased risk for anastomotic leak among those who received NSAIDs.
A new study found that high-risk neuroblastoma cells use an efficient but erroneous DNA repair pathway, giving them a survival advantage. This alternative repair mechanism may be the target of new therapies to improve treatment options for children with neuroblastoma.
Researchers at Penn Medicine have discovered a mutated ATRX gene as a potential biomarker for aggressive brain tumors and rare adrenal tumors. The study found that 13% of tumors had ATRX mutations, which were more common in clinically aggressive cases.
A new study in Journal of Consumer Research reveals that consumers may not perceive bundled products as a better value. Retailers need to highlight the benefits of package deals to attract customers. By presenting both individual and bundled options, businesses can make consumers aware of the added value and increase sales
The BMJ reports on the widespread corruption in India's private medical colleges, where capitation fees of up to 10 million rupees are paid for admission. This leads to a decrease in government seats and an increase in inequity between rural and urban healthcare standards.
Vanderbilt University researchers found that chlorhexidine cloths did not reduce health care-associated infections in critically ill patients compared to non-antimicrobial cloths. The study analyzed data from over 9,300 ICU patients and showed no significant difference in infection rates between the two groups.
The study found a significant decrease in mortality rates among extremely premature infants between 2000 and 2011, with the largest declines observed in infants born at 23 or 24 weeks of gestation. Deaths attributed to respiratory distress syndrome and immaturity accounted for the majority of the reduction in mortality.
Researchers at the University of Illinois have found that safeners activate a defense
Researchers have discovered tiny magnetic particles in meteorites that retain a faithful record of the magnetic fields generated by their parent bodies. By analyzing these particles, scientists were able to reconstruct the history of magnetic activity on the meteorite parent body and capture the moment when the core finished solidifying.
Researchers have developed a new method for studying streams in different climates and continents, introducing the Stream Biome Gradient Concept. This concept can improve how researchers understand how to regulate and conserve streams and protect water quality.
Researchers from the Keck School of Medicine of USC led a global consortium to identify eight common genetic mutations that appear to age the brain an average of three years. The discovery could lead to targeted therapies and interventions for Alzheimer's disease, autism, and other neurological conditions.
Yale researchers developed a new bio-containment method using genetically modified bacteria that require a synthetic amino acid to activate genes. This approach solves a major obstacle to widespread GMO use, ensuring safer confinement of organisms in the environment.
The article discusses the five main strategies scholars use when writing review articles, highlighting their unique approaches and strengths. Dr. McGaghie emphasizes the importance of recognizing and respecting these traditions while embracing new approaches to research synthesis.
A new study in the Journal of Marketing suggests that consumers believe products with central rather than peripheral recycled features are greener. Central attributes with environmental benefits imbue the entire product with greenness, according to authors Andrew D. Gershoff and Judy K. Frels.
A new study proposes a new model to evaluate medical schools' production of academic physicians with biomedical research careers. The model uses relevant and accessible objective criteria, replacing the subjective criteria used in the current USN&WR rankings system.
Researchers capture asteroid magnetic field moments, revealing extended lifetimes and creating mechanisms similar to the Earth's own magnetic field. Ancient meteorites provide a cosmic archaeological mission, shedding light on the magnetic history of asteroids and their impact on the Earth's core future.
A new study suggests that online searches for specific car features can predict consumer purchases with greater accuracy than brand names. Researchers analyzed six years of car sales data and found that searches for features like body type and fuel economy were key indicators of future purchases.
A new study finds that consumers are more interested in a new product when they visualize using it in the past, but less interested when visualizing in the future. This effect varies depending on how easy or difficult it is for consumers to visualize using the product.
Researchers at LSU Health New Orleans School of Medicine have discovered a toxic fragment of an Ebola virus protein that can change membrane permeability. The Delta peptide fragment has been shown to block the virus from attaching to already-infected cells, offering potential new insights for treatment and prevention.
Close monitoring of small renal tumors can be an alternative to surgery, with low rates of tumor growth or death observed. The study's findings suggest that actively monitoring these tumors in high-risk patients may prove safer than immediate surgery.
A new study found that ultra-high pressure processing can improve the color, hardness, and chewiness of salmon flesh. The treatment also inhibited microorganism proliferation, increasing shelf life.