Researchers at the University of Basel discovered that the choroid plexus produces key signaling factors that regulate adult neural stem cells. As people age, these signals change, affecting stem cell behavior and leading to a decrease in new neuron formation.
A new study from Carnegie Mellon University reveals four distinct stages of problem solving: encoding, planning, solving, and responding. The research uses functional MRI to analyze brain activity patterns and provides insights into how students think when solving math problems.
Researchers found that small earthquakes along California's San Andreas Fault are triggered by tidal forces and provide insights into the fault's strength and behavior. The study's discovery may offer new warning signals for predicting major quakes.
Scientists discover gene BCL11A responsible for a new intellectual disability syndrome, which affects brain development and function. The study reveals that two healthy copies of the gene are necessary for normal brain cell development.
Researchers developed a detailed model system to study the Barr body's highly organized structure, revealing two distinct lobes with smaller active DNA domains. Topologically associating domains play a significant role in gene expression within the otherwise inactive lobes.
A team of scientists released key recommendations to build and sustain land in coastal Louisiana using Mississippi River sediment diversions. The plan aims to mimic natural processes that originally built the land, taking advantage of winter flood peaks and spring sand, while minimizing socio-economic effects.
Deciduous trees absorb a large amount of snowmelt water, equating to 17-20 billion cubic meters per year, with potential to create favorable conditions for thunderstorms. The study's findings have critical implications for understanding boreal forest hydrology and ecology.
A team of scientists has created an online resource, systemsDock, to virtually check the effectiveness and specificity of potential drugs. The tool allows users to screen multiple drugs against multiple biological targets, providing a comprehensive understanding of drug interactions with the biological system.
Researchers found that diverse spider societies composed of both docile and aggressive spiders are more resilient to temperature fluctuations than those with a single personality. This discovery has implications for restoring animals in changing habitats.
Two new studies estimate the economic cost of malignant and non-malignant blood disorders in Europe, with a total cost of €23 billion in 2012. Blood cancers account for a significant proportion of cancer costs, with healthcare expenses being twice as high as average across all types of cancer.
A new study reveals four stages of problem-solving: encoding, planning, solving, and responding, using functional MRI to analyze brain activity patterns. The method holds promise for designing more effective classroom instruction and broader applications in cognitive research.
Children who experience inadequate or disrupted sleep are more likely to develop depression and anxiety disorders later in life. A study funded by the NIH found that poor sleep impacts children's emotional health by altering positive emotional experiences, leading to increased negative emotions and diminished impulse control.
GPM data showed heavy rainfall on Estelle's eastern side, later shifting west of center. Precipitation rates reached over 65 mm/h, with some storms having heights exceeding 11.6 km.
A new study suggests that gut bacteria in modern humans and apes coevolved for millions of years to help shape their immune systems. Researchers found that bacterial species distinct to one host were rarely transferred to other hosts, indicating unique patterns of evolution along with their hosts.
Research published in Injury Prevention journal reveals that nearly three out of four cases of laundry pod detergent exposure were diagnosed with poisoning compared to contact dermatitis for other detergents. Children under 5 accounted for most of the cases, and hospital admissions were more common for pod exposures.
Smoking is a leading risk factor for subarachnoid hemorrhage in women, with those who smoke up to 30 cigarettes per day facing the greatest danger. Quitting smoking significantly reduces the risk of this condition, making it an essential step in maintaining brain health.
Researchers at Lawrence Berkeley National Laboratory have harnessed carbon dioxide to neutralize toxicity in ionic liquids, streamlining the biofuel production process and reducing costs. The process could significantly lower production expenses and make biofuels more sustainable.
A new study found that baby migratory songbirds face different risks in the nest and after leaving, with some species experiencing higher mortality rates during post-fledging stages. Researchers used radio transmitters to track young birds and documented survival rates, shedding light on factors affecting their survival.
A recent study found that only 53% of Americans are aware of food waste being a problem, despite its negative environmental impacts. The study identified practical benefits such as reduced risk of foodborne illness, but also feelings of guilt and misconceptions about the importance of food waste.
Researchers found that combining three different antibiotics can often overcome bacterial resistance, with some combinations killing 100% of bacteria. The study's findings could be a major step toward combating drug-resistant infections, and the team plans to make open-access software available for other scientists and clinicians to use.
Researchers studied two contemporary groups of hunter-gatherers, the Agta of Philippines and Mbendjele of Republic of Congo, revealing surprising similarities in their three-tiered social networks. This multilevel structure appears to buffer individuals against day-to-day shortfalls in foraging returns.
A new system called Dreambit predicts how a person would look with different hairstyles, colors, and appearances by analyzing input photos and searching the internet for similar images. The software can also age-progress faces and help identify missing children or people evading the law.
A recent survey by CAMH found that 328,000 Ontario students in grades 7-12 reported moderate-to-serious psychological distress, with girls twice as likely to experience it. The survey also highlighted concerns around screen time, social media use, and problem gaming, which are contributing to the rising levels of distress.
Researchers at North Carolina State University integrated novel oxides onto a computer chip, enabling new applications such as sensors and non-volatile memory. The integration technology allows for faster, more efficient devices with improved performance.
Researchers at University of California - San Diego create method to improve light interaction with small details called glints on surfaces, enabling accurate rendering of materials with metallic finishes and injection-molded plastics. The new algorithm is 100 times faster than current methods and can be used in animations.
The Bellerophon Environment for Analysis of Materials (BEAM) platform unites imaging technologies with advanced data analytics and high-performance computing to accelerate materials discovery and design. This innovation enables near-real-time processing, analysis, and visualization of large experimental datasets.
A new study reveals that certain bacteria in the human gut have been passed down over millions of years, guiding early intestine development and influencing immune systems. The researchers found genetic evidence that these bacteria split into distinct strains at around the same time as their hosts diverged from a common ancestor.
Researchers at Osaka University have discovered that error signals in motor cortices drive adaptation in reaching, a key finding in motor neuroscience. The study used artificial electrical stimulation to induce trial-by-trial improvements in motor control, shedding light on the neural mechanisms underlying motor learning and adaptation.
Researchers found that just 1-10% of beta cells control islet responses to glucose, serving as pacemakers for insulin secretion. This discovery could pave the way for therapies targeting these 'hubs' to treat type 2 diabetes.
A key gene called AUF1 determines whether adult stem cells can regenerate muscle after injury and with age. The study found that mice engineered to lack the AUF1 gene showed reduced stem-cell-driven repair, leading to muscle breakdown.
A new study found that starting blood-thinning medications within 72 hours of hospital arrival significantly reduces the likelihood of life-threatening blood clots in patients with traumatic brain injury. The study also showed no increase in risk of bleeding complications or death.
Researchers at the University of Montana discovered a previously unknown second fungus that is part of the symbiotic relationship between an alga and a fungus in many common lichen species worldwide. The findings, published in Science, suggest that the definition of lichen should be revised to include multiple fungal partners.
Transgenic Huntington's disease monkeys exhibit a range of symptoms, including motor problems, neurodegeneration, emotional dysregulation, and immune system changes. The study strengthens the use of HD monkeys as a model for evaluating emerging treatments before human clinical trials.
Arrhythmotech aims to detect nerve activity using its device capable of detecting the body's fight-or-flight response on the skin. The company will collaborate with researchers at the Mayo Clinic and Cedars-Sinai Medical Center, with a goal of making its method widely available for research, education, and patient care.
Researchers discovered that metacyclic trypanosomes are highly infectious and can colonize the skin of mice, leading to systemic infection. A subpopulation of parasites stays in the skin for at least 7 days, multiplying and interacting with local fat cells and collagen fibers.
Researchers at the University of Pittsburgh School of Medicine and McGowan Institute for Regenerative Medicine showed significant improvement in strength and range of motion, as well as evidence for skeletal muscle regeneration in patients treated with bioscaffolds. The study demonstrated the effectiveness of regenerative medicine in i...
A new study found that sexual minority boys and girls are more likely to engage in unhealthy eating habits, with lesbian and bisexual girls facing a widening gap in rates. The study analyzed data from youth ages 12-18 and found disparities in disordered eating behaviors between sexual minority teens and their heterosexual peers.
A new study published in Pediatrics analyzed nearly 7,000 head impacts during a high school football team's season and post-season, finding that player-vs.-player hits resulted in the most severe impacts. The study's findings support recent guidelines encouraging players to avoid leading with their heads when hitting another player.
Research found that retained metabolites in the blood are associated with impaired cognitive function in patients with kidney failure. The study suggests that interventions may be necessary to safeguard the mental health of these patients.
The development of global standards for vaping products is essential to promote innovation and protect consumers. Different regulatory approaches in the EU and US can hinder growth and stifle innovation, as noted by British American Tobacco's Head of R&D, Marina Trani.
A new species of rain frog, Pristimantis prometeii, has been discovered in southwestern Ecuador and named after the Greek hero Prometheus. The frog grows to 2-3 cm and is part of a group of directly developing frogs that do not have an aquatic tadpole stage.
The new Askaryan Radio Array detector is making waves with its ability to penetrate through Antarctic ice and detect high-energy neutrinos. Scientists are optimistic about the potential for this technology to reveal secrets about the universe's origins and evolution.
The American Society of Hematology (ASH) has established a $3 million annual Bridge Grant program to support blood disease research. This initiative aims to ensure that promising researchers in hematology continue their work despite limited NIH funding.
Researchers identified ASCL1 as an essential protein in the development of small cell lung cancer, and deleting it in mice prevented cancer formation. The study highlights a new potential target for treatment, offering hope for improving survival rates for patients with this devastating disease.
Researchers have uncovered yeast as a hidden third partner in lichen symbiosis, producing chemicals that help ward off predators and repel microbes. This discovery explains the genetic similarities between genetically identical lichens with distinct physical features.
A recent study from the Neuromed Institute reveals that two previously separate processes converge into a single cell component, the autophagoproteasome. This discovery provides a new understanding of autophagy, a critical mechanism for cellular renewal and waste removal.
A new study reveals that the evolution of gut bacteria in humans and hominids parallels ape evolution, suggesting a long-term co-evolution between hosts and microbes. The research sheds light on the importance of the human microbiome and its connection to our evolutionary history.
Researchers have identified a panel of genes that can help predict whether a transplanted kidney will develop fibrosis, leading to organ failure. The study's findings have the potential to change how doctors monitor and manage renal transplant patients.
Research suggests that people with chronic low back pain are more likely to use illicit drugs, including marijuana, cocaine, and methamphetamine. Those with a history of illicit drug use are also more likely to have a prescription for opioid analgesics.
The LUX experiment has completed its search for dark matter, yielding no trace of a particle despite achieving record sensitivity. The results provide critical guidance for future dark matter experiments by eliminating potential models.
Six Canadian innovations, including a low-cost drill system and an HIV self-test application, will receive $10 million in scale-up funding from Grand Challenges Canada. The projects aim to improve global health in developing countries by providing innovative solutions for diseases such as diarrhea, cervical cancer, and HIV.
Researchers found that the direct and indirect pathways in the basal ganglia play a crucial role in controlling actions, with the direct pathway sustaining action and the indirect pathway allowing switching between actions. This new model could have therapeutic implications for treating diseases like OCD and ADHD.
A Cornell University study found that run-down schools contribute significantly to low test scores and poor academic achievement, accounting for 70% of the issue. Students attending such schools are more likely to miss classes and exhibit high absenteeism, hindering their ability to learn.
A five-year program project grant will investigate the genetic basis of acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury (VILI). The research aims to develop a more personalized medicine approach to ARDS and VILI, enabling physicians to make informed medical decisions.
Researchers at Harvard John A. Paulson School of Engineering and Applied Sciences have developed a dielectric elastomer with broad motion range that requires relatively low voltage and no rigid components. This innovation addresses key challenges in soft actuation and opens doors for various applications in soft robotics.
Researchers designed and built large protein icosahedra with potential applications in targeted drug delivery and vaccine development. The structures were created using computational and biochemical approaches, allowing for the design of complex structures from scratch.
A DNA-modulating drug, BET inhibitor, attenuates CF lung inflammation by suppressing Th17 cell response and inflammatory factor release. In a mouse model, BET inhibitor treatment decreases lung inflammation without promoting infection, suggesting potential therapeutic use for CF patients.
Scientists at Hokkaido University measured eye pressure in sleeping patients with obstructive sleep apnea syndrome for the first time, discovering an unexpected correlation between the two conditions. This study sheds light on the potential mechanisms underlying glaucoma development in patients with OSAS.
A new study found that background noise in homes and schools impairs toddlers' word learning skills. However, providing additional language cues can aid young children in overcoming this difficulty. The research suggests that reducing background noise or highlighting important information can help children learn effectively.
A breakthrough in quantum tomography has been achieved by RMIT researchers, demonstrating a new technique that significantly reduces resources and improves robustness against noise. This innovation enables the characterisation of large quantum states, a critical bottleneck in quantum information science.