Chinese scientists have developed a facile approach for the rapid and maskless fabrication of bio-inspired hierarchical structures using multi-beam laser interference. This technique enables the creation of large-area, low-cost, and high-volume 3D fabrication of micro and nanostructures. The method is simple and efficient compared to c...
Researchers found trees exchange large quantities of carbon among different species through mycorrhizal fungi. This discovery questions the concept of tree individuality and adds a new dimension to the role of these fungal networks in forests.
Researchers have developed a potentially life-saving drug therapy called ALM that can reduce internal blood loss by up to 60% in traumatic injuries. The treatment, administered intravenously, has shown promise in treating shock and stabilizing vital organs.
Early antibiotic use can permanently alter the diversity of children's immune cells, potentially leading to increased risks of inflammatory bowel disease and allergies. The study aims to understand how antibiotics impact T cell education and balance in the gut microbiota.
Researchers used SPECT-MRI fusion to assess sentinel lymph nodes in early-stage cervical cancer patients, finding that it could identify metastases with high accuracy. This non-invasive approach may reduce the need for surgical removal of lymph nodes and improve patient outcomes.
Researchers developed a computer algorithm that accurately identified autism spectrum disorders using fMRI brain scans. The classifier worked across diverse populations, including Japanese and American adults, with an average accuracy of 85% and 75%, respectively.
A new study will explore the extent to which entrepreneurship empowers women refugees in Arab countries, assessing its impact on poverty alleviation. The research project will develop recommendations for aid programs across the Middle East and Africa to enhance effectiveness.
The NOvA particle physics experiment has successfully detected the transformation of muon-type neutrinos into electron-type neutrinos, a process known as neutrino oscillation. This discovery provides valuable insights into the subatomic world and the evolution of the universe.
A new study reveals that a genetic mutation protecting malaria parasites against a key anti-malarial drug eventually kills them by stopping energy production. This discovery could improve malaria treatment and prevent mass drug resistance from spreading.
Scientists at University of Maryland School of Medicine identified a key pathway for regulating the 'switch' between wakefulness and sleep. The study found that BK potassium channels play a critical role in encoding circadian rhythm in the brain, particularly during inactivation.
A new triple combination treatment of sofosbuvir/velpatasvir and GS-9857 achieved a high sustained virologic response rate of 99% in patients with HCV genotype 1, 2, 3, 4 and 6. The treatment was generally safe and effective, even in patients who had previously received direct acting antivirals.
A new combination treatment of sofosbuvir, velpatasvir, and GS-9857 demonstrates safety and efficacy in patients with genotype 1 HCV infection. The study achieved high sustained virologic response rates, with 98% of patients responding to the three-drug combination.
A randomized clinical trial found neratinib plus paclitaxel to delay central nervous system (CNS) metastases and reduce their frequency compared to trastuzumab plus paclitaxel in women with ERBB2-positive breast cancer. However, median progression-free survival was similar between the two groups.
Mutations in the RERE gene can cause developmental problems typical of 1p36 deletion syndrome, a relatively common cause of intellectual disability. The study identified 10 patients with RERE mutations, who exhibited similar medical conditions to those with 1p36 deletions.
A team of researchers from Cardiff University has provided new evidence on how deep sea creatures survived the asteroid strike that wiped out the dinosaurs. The study found that some forms of algae and bacteria were living in the aftermath of the disaster, providing a slow trickle of food for creatures near the seafloor.
A late-breaking abstract at the European Lung Cancer Conference presented findings on osimertinib's effectiveness as first-line treatment for EGFR mutated non-small-cell lung cancer. The study showed a high overall response rate and prolonged progression-free survival, suggesting that osimertinib may alter the biology of the disease.
A new study suggests that an eslicarbazepine acetate taken once a day may control seizures in people with partial seizures as well as carbamazepine taken twice daily. The six-month study showed that 71% of those taking eslicarbazepine were seizure-free, compared to 76% of those taking carbamazepine.
A nationwide study found that women living in homes surrounded by more vegetation had a 12% lower overall mortality rate and stronger associations with reduced respiratory disease and cancer mortality. Improved mental health was estimated to explain nearly 30% of the benefit from living around greater vegetation.
A team of entomologists has discovered 12 new scuttle fly species in Los Angeles, showcasing the city's impressive insect diversity. The BioSCAN project, launched in 2013, aims to document urban faunal collections, emphasizing the importance of constant scientific curiosity and attention to rapidly changing environments.
Researchers at Rice University have discovered 'Teslaphoresis', a phenomenon where carbon nanotubes self-assemble into long wires using a Tesla coil's force field. The team, led by Paul Cherukuri, reported their results in ACS Nano and demonstrated the ability to assemble and power circuits using the force field.
The elbasvir/grazoprevir combination was effective in HCV genotypes 1 and 4 with fewer overall side effects, resulting in an SVR12 of 99.2% compared to 90.5% for sofosbuvir/pegylated interferon. The new treatment demonstrated superior efficacy especially in hard-to-treat patients.
A genome-wide association study has identified two genes, PNPLA3 and SLC38A4, that increase the risk of developing severe alcoholic hepatitis in heavy drinkers. The study found that individuals with these genetic variants are more susceptible to developing this serious and life-threatening illness.
Professor René Rizzoli, a leading Swiss investigator, has been awarded the ESCEO-IOF Medal for his groundbreaking work in basic bone science. The medal recognizes his contributions to understanding bone and mineral metabolism, with over 800 publications to his name.
A Florida State University researcher found that Latino immigrants experience significant stress due to threats to 'familismo', deeply held cultural beliefs about the centrality of family. This ambivalence can have a negative impact on overall health and well-being, particularly in terms of parenting and economic adjustment.
An interdisciplinary team will focus on ethics and research in pregnancy, beginning with the current Zika context. Bioethicists aim to develop guidance for conducting research with pregnant women in public health crises.
The Hastings Center has launched a three-year project to examine the fundamental questions of using gene editing in humans, including its impact on human flourishing and core values. The project aims to develop new scholarship, equips journalists, and prepares teachers to engage with these issues.
A type of thyroid cancer, EFVPTC, is being reclassified as non-invasive and low-risk due to its low recurrence rate. The new name, NIFTP, guides pathologists in diagnosis and reduces aggressive treatment, potentially saving lives and reducing healthcare costs.
A randomized controlled trial enrolls 350 firefighters from Tampa Bay's three largest fire departments to assess the effectiveness of a worksite exercise regimen. The study aims to reduce low back injury and disability, improving health and preparedness for firefighters.
A national research study will focus on the effectiveness of specific carbohydrate diets and Mediterranean-style diets to induce remission in patients with Crohn's disease. The study, led by Dr. James Lewis, aims to provide high-quality data and guidance for incorporating diet modifications into the treatment of the disease.
Scientists have confirmed that as people age, they accumulate gene mutations in their mitochondria, which can limit energy production and impair cellular function. Researchers recommend screening stem cells for mitochondrial DNA mutations to ensure their therapeutic value.
A new study published in The Journal of Urology found no differences in penile sensitivity between circumcised and intact men. The researchers also challenged the notion that the foreskin is the most sensitive part of the adult penis. No differences were observed in sexual functioning between the groups.
Researchers at TSRI have integrated biomedical data into Wikidata, enabling easy access and linking of genes, proteins, and more. The project aims to create a comprehensive, uniform database that can be searched and updated by anyone.
Research finds that proton pump inhibitors, widely used for heartburn and ulcers, can lead to kidney function decline, chronic kidney disease, and kidney failure. Long-term use of these medications significantly increases the risk of developing kidney problems.
Bacteria's ability to form membrane vesicles and biofilms, crucial for disease-causing abilities and antibiotic resistance, has been linked to explosive cell lysis. The study reveals that a previously unknown enzyme disrupts the cell wall, releasing essential cellular components.
The European Research Council has awarded €647 million in funding to 277 senior researchers, enabling them to pursue innovative projects with potentially significant impacts on science and society. The grants, worth up to €2.5 million each, will support research in various fields, including life sciences, social sciences, and humanities.
Lay health advisors play a crucial role in reducing health disparities among medically underserved groups. Research from Roswell Park and Columbia University found that support from academic institutions is key to their success, with partnerships leading to higher retention rates. The study also highlights the importance of clear role ...
Professor Joseph M. Suflita, a leading researcher at the University of Oklahoma, has been awarded the 2016 DuPont Industrial Biosciences Award for his distinguished achievements in applied and environmental microbiology. His work focuses on bioremediation and the role of anaerobic microorganisms in contaminant degradation.
Researchers from Johns Hopkins Medicine found that immune cells associated with allergies can promote healing of mouse muscle wounds when paired with biomaterial scaffolds. The discovery suggests a pivotal role for type 2 helper T cells in regulating the regenerative process, which may lead to novel strategies for tissue regeneration.
A new study found that patients with a prior history of hepatocellular carcinoma and treated with direct-acting antivirals for Hepatitis C have a higher-than-expected early recurrence rate of their liver cancer, with rates exceeding 40% in some subgroups. The recurrences may be due to a weakened immune system following DAA therapy.
Researchers have stabilised ultra-long carbyne chains with over 6,400 carbon atoms, surpassing previous records. The new method uses double-walled carbon nanotubes to create the stable chains, which could lead to new nano-electronic applications.
A team of researchers has created the first comprehensive in vivo fitness landscape of a gene, which provides a way to visualize and predict evolution. The findings show that about 1 percent of point mutations are beneficial to an organism, while 42 percent are harmful, and two harmful mutations interacting can lead to more harm.
Dr. Lyons-Weiler examines successes in biomedical translational success, including breast cancer receptor research and individualized treatments, as well as problems with modern healthcare. He also critiques examples of 'Shamwizardry' in the pharmaceutical industry.
A new project, NANOBED-MX, will offer researchers and entrepreneurs access to space technology with minimal investment. The program builds on the UKube-1 CubeSat experience and aims to unlock commercial opportunities in developing countries.
A study estimated the number of children born with Down syndrome each year in Massachusetts, along with pregnancies terminated due to prenatal diagnosis. The study found a higher incidence of termination in the Northeast and among Asians/Pacific Islanders.
A multi-institution study found that nipple-sparing mastectomies are as effective as traditional mastectomy in preventing breast cancer in women with a genetic mutation called BRCA. The procedure, which preserves the nipple and surrounding skin, was found to be safe and effective in reducing breast cancer risk.
Researchers found that Greek dancing improved jumping ability, muscular strength, and lower limb endurance in cardiac rehabilitation programs. Patients who participated in the study jumped higher and faster, had stronger legs, and could walk further, demonstrating more endurance.
Researchers have slowed glioblastoma tumor growth in mouse models using a high-fat, low-carbohydrate diet. The modified diet increased life expectancy by 50% and reduced tumor progression by a similar amount.
A top-tier team, led by UTSA Professor William Dupont, is working on a historic restoration project in Cuba to preserve Ernest Hemingway's home. The new archival storage facility will be the first building in Cuba constructed using US materials since the late 1950s.
Researchers at the University of Missouri have discovered a compound that not only lowers cholesterol but also kills prostate cancer cells. The study found that the compound, initially developed as a cholesterol-fighting molecule, reduced prostate cancer cell growth and caused cancer cell death in human and mouse models.
A region of specific proteins called SPX domain signals the phosphate status to cells, regulating phosphate uptake. InsP signaling molecules interact with SPX domains to control phosphate homeostasis in various organisms.
An international team has compiled the largest library of bat sounds, allowing researchers to accurately identify and differentiate between 59 bat species found in Mexico. The developed method can be used to monitor biodiversity change and characterise bat communities in different regions.
A study found that propofol, a commonly used anesthetic, induces loss of responsiveness by diminishing brain connectivity in the frontal cortex. The researchers also observed significant changes in resting state brain networks.
A new study from Karolinska Institutet reveals a feedback regulatory system through which dopamine controls its own activity, regulating prolactin levels and potentially mitigating sexual side effects of antipsychotic drugs.
Researchers have developed a new approach to convert methane into methanol using copper-containing silicon aluminum compounds as catalysts at constant temperatures and high pressures. This process can potentially reduce the energy waste associated with current industrial methods.
Researchers created a mathematical model that reproduces the animals' internal calculations, revealing the existence of a 'separatrix angle' that changes throughout the day. The model predicts real-life behaviors in flight simulators and provides insights into monarch navigation.
Researchers at Wayne State University are developing novel aminoglycoside antibiotics with reduced toxicity and decreased resistance, aiming to combat multidrug-resistant diseases. The project, led by David Crich, will evaluate synthetic compounds in vitro and animal models for efficacy and antibacterial activity.
Research highlights the impact of dietary habits on male reproductive potential, with obesity found to promote hormonal dysfunction and affect fertility. The study emphasizes the need for policymakers and media attention to address this growing health issue.
A joint project by universities in Mainz and Hohenheim aims to find better-tolerated wheat varieties. The researchers are studying the causes of non-celiac-non-allergy wheat sensitivity (NCWS) and its connection to wheat proteins called alpha-amylase-trypsin inhibitors.
Salk Institute scientists have developed a new reagent to map the brain's complex network of connections, 20 times more efficient than the previous version. The improved tool allows researchers to visualize neural circuitry and learn more about conditions like motor diseases and neurodevelopmental disorders.
A study by Columbia University Irving Medical Center found that heavy cannabis users have lower dopamine release in the brain's striatum, a region involved in working memory and attention. This effect is similar to other addictive substances and may impair learning and behavior.