A University of Pittsburgh researcher has successfully regenerates heart tissues in mice using components from zebrafish, a skill lost among humans and other mammals. Human heart cells have also shown promising results in vitro, paving the way for potential treatments for heart disease.
Researchers found that a new triple regimen of integrase inhibitor Dolutegravir decreases viral load in semen very quickly, reducing the risk of HIV sexual transmission. This treatment approach could potentially shorten previous antiretroviral prophylaxis.
A new special section investigates how human motivations drive children's prosocial behavior, including empathy, sharing, and helping. The study reveals that children's cardiac patterns can predict their empathetic responses to others.
A new color-coding tool enables scientists to track live blood stem cells over time, revealing how blood disorders and cancers like leukemia arise. The tool has many implications for hematology and cancer medicine, including understanding clonal diversity and regulating its development.
A study of English schoolchildren found that the London 2012 Olympics inspired many to try new sports and activities, but levels of physical fitness worsened. Despite positive associations with increased activity and lower BMI among some participants, overall cardiorespiratory fitness declined significantly after the event.
Researchers found a link between the loss of hyaluronan and AEC2 stem cell failure, leading to scarring in lungs. The study highlights potential treatment pathways using drugs that stimulate AEC2 cell reproduction.
A study published in Mayo Clinic Proceedings found that newborn telemedicine consultations can positively impact patient care by providing enhanced access to neonatologists. This resulted in one-third of babies being able to stay with their families in the local hospital, increasing the value of care and potential cost savings.
A recent study published by the American Psychological Association found that men who conform strongly to traditionally masculine norms are more likely to have poorer mental health outcomes. Furthermore, these individuals are also less likely to seek psychological help, highlighting the potential harm of sexist attitudes on men's menta...
Researchers found that 2-dose HPV vaccine regimens for girls and boys aged 9-14 years had noninferior antibody responses compared to 3-dose regimens for adolescent girls and young women. The study suggests using a 2-dose schedule could improve adherence to HPV vaccination programs and reduce healthcare costs.
Researchers at Caltech have confirmed that the pseudogap phase represents a new state of matter with properties different from the superconducting state. The discovery breaks nearly all spatial symmetries, providing clues about the origin of high-temperature superconductors.
A new Tel Aviv University study reveals that agreeable women, regardless of dominance, face financial retribution for being perceived as 'too nice.' Dominant women are also underpaid compared to their male colleagues. The researchers analyzed data from 375 men and women at a Dutch multinational electronics company.
Researchers in Brazil have created 3-D virtual reality models of unborn babies using fetal MRI results. The technology allows doctors to visualize the fetus's internal structure, including the respiratory tract, which can aid in assessing abnormalities.
A new study found nearly five deaths per 1000 employed Australian health care professionals were caused by drugs from 2003-2013. The majority of these deaths involved females in their mid-40s with a mental health condition and the intent to self-harm.
Australian researchers discovered that immune T cells develop in 'families' programmed to divide and die at different times after an infection is detected. This understanding may underpin future improvements in vaccination and the treatment of autoimmune diseases.
Researchers have developed a method to dissolve layered materials in liquids, producing single layers of 2D nanomaterials that can be applied over large areas at low costs. The new approach enables the creation of scalable solutions for various industrial applications.
A recent study found that obesity in adolescence is associated with weakened bone structure, including increased cortical porosity and decreased trabecular density. This suggests that adolescents with high visceral fat mass and low muscle mass are at risk for permanent bone loss.
Researchers at Scripps Research Institute have developed a new structure-based drug design strategy to target the estrogen receptor, reducing resistance and side effects in hormone-driven breast cancer treatments. The approach uses x-ray crystallography to visualize how drugs interact with the receptor, allowing for the creation of bio...
A new species of quillwort (Isoetes mississippiensis) discovered in Mississippi, USA, is the largest representative of its genus, with two known populations at risk of extinction. Further study reveals its genetic makeup and potential role in biodiversity and conservation science.
Adoption of targeted therapies for chronic lymphocytic leukemia (CLL) could raise treatment costs in the US by almost 600 percent, according to a Massachusetts General Hospital-led research team. The average annual cancer treatment cost has increased from below $10,000 to over $100,000.
A systematic review of medication errors found that serious impacts were rare, occurring in only zero to one percent of medication errors. Good practice requires a team-based approach to prevent medication errors in nursing homes.
Researchers have developed a technique to remove mutated DNA from mitochondria, which could help slow or reverse aging. The study found that increasing mitophagy, a form of cellular quality control, can reduce the levels of mutant mtDNA in cells.
Residents selectively extend work shifts to facilitate care transitions, stabilize critically ill patients, and perform routine responsibilities. However, senior residents reported more frequent duty hour violations, with junior residents having the highest rate of frequent violations.
A new study of mortality patterns in humans, monkeys, and apes reveals that men have yet to catch up with women in terms of life expectancy. Despite advances in medicine and public health, the gender gap remains unchanged, with females outliving males across all primate species.
Researchers have developed a blood test that can predict how well small-cell lung cancer (SCLC) patients will respond to chemotherapy. The test analyzes patterns of genetic faults in circulating tumour cells, providing insight into treatment response and drug resistance mechanisms.
Researchers have developed an integrated model that connects atmospheric and lake body interactions, enabling feedback between variables. This two-way coupling approach simulates hydrodynamics of the Great Lakes region with high resolution, providing a more nuanced view of regional climate change.
Research reveals that African American and Latino children have significantly higher rates of corn, shellfish, and fish allergies compared to white children. The study found that wheat allergy is also more common among African American children, potentially contributing to higher rates of anaphylaxis and emergency room visits.
Researchers at TUM develop a new method for non-destructive testing using ultrasound that combines a computerized model and experiment to provide precise information on the inner world of objects. This method uses waveform inversion to utilize the entire information content of the wave field measured, providing improved results.
A new sensor system can detect worsening heart failure conditions in patients with high accuracy, potentially preventing hospitalizations and death. The system, developed by Boston Scientific, uses a suite of sensors to track heart rate, activity, breathing, and other physiological measures.
Researchers use a femtosecond X-ray laser to observe the water-splitting reaction in detail, shedding light on how oxygen is formed. The study provides new insights into the molecular mechanisms of photosynthesis.
Researchers found that runners wearing minimal trainers and landing on the ball of their foot had lower loading rates, reducing injury risk. This study suggests that minimal shoes can be beneficial for runners who adopt a forefoot strike pattern without cushioning.
An international team of researchers visualized the process by which plants split water to produce oxygen using X-ray free-electron laser technology. This breakthrough enables the study of oxygen molecule formation and paves the way for the development of efficient clean hydrogen fuel devices.
A large study found that thiazide diuretics, such as chlorthalidone, are associated with a lower risk of hip and pelvic fractures. The analysis included 22,180 participants followed for up to eight years and reported a 21% lower risk of fractures in the chlorthalidone group compared to other treatments.
A study found that butterfly mothers preferentially select leaves from vulnerable Cycas species over less damaged ones, resulting in a greater number of eggs being deposited. However, this skill was lost in populations experiencing novel host species over time.
A new study reveals a high prevalence of military sexual trauma (MST) among transgender veterans, with nearly one in five transgender men and one in seven women screened positive. MST was associated with an increased likelihood of mental health conditions such as posttraumatic stress, personality disorders, and depression.
A foreign beetle species, Ocypus nitens, has been detected in Ontario, Canada, and Vermont, USA, through citizen science efforts. The rove beetle was identified using digital photographs from the BugGuide online portal.
Researchers developed guidelines for fluidized bed reactors to tailor filter design to local conditions, preventing phosphorus deposits and algal blooms. The study's findings could lead to significant cost savings and environmental benefits.
Researchers found that pancreatic beta cells release proteins and their packaging, exosomes, which target the immune system. The study suggests a new direction for treatments focused on inhibiting immune cell activation.
Researchers identified six core emotional storylines: rags to riches, richness to rags, man in a hole, icarus, Cinderella, and Oedipus. These findings may help create compelling stories and teach common sense to AI systems.
A randomized clinical trial found that long-term collaborative care and occupational therapy did not slow functional decline in persons with Alzheimer disease. The study suggests that new assistive devices, home modifications, and technologies are needed to support patients and families at home.
The ginkgo genome reveals extensive expansion of gene families for defensive mechanisms against pathogens and insects, as well as unique traits such as transposable elements. The sequence provides a genetic resource for studying early events in tree evolution and the history of demography and distribution.
Researchers have sequenced the genome of Onchocerca volvulus, the parasite responsible for river blindness, identifying proteins that could be targeted with existing drugs or developed into new treatments. The study also reveals promising areas for developing a preventive vaccine against the disease.
Researchers successfully engineered human intestines with functioning nerves using pluripotent stem cells, enabling the study of severe intestinal nerve disorder Hirschsprung's disease. The technology also allows for testing new therapeutics in lab-engineered human intestine before clinical trials.
A new study finds that dementia rates are decreasing in the US, particularly among those with more years of education. However, three risk factors – diabetes, high blood pressure, and obesity – are on the rise and could offset these gains.
Researchers have identified a specific site on the surface of the human astrovirus that can be targeted for development of a vaccine or antiviral therapy. By binding to this site, neutralizing antibodies can block the virus's ability to infect human cells, providing a potential roadmap for treatment options.
A team of international scientists has discovered beta-keratin in a 130 million-year-old bird feather fossil, providing evidence that melanosomes are present in these structures. This finding sheds new light on the molecular preservation of tissues in ancient fossils.
Researchers developed MEMOIR to record cellular histories in genomes, allowing them to analyze cell relationships, communication patterns, and influential events. The technique aids in understanding tissue and animal development, as well as the abnormal development of diseased tissues like tumors.
Researchers found that chimpanzees copy their mothers' grooming styles, including high-arm grooming, which is not closely associated with group identity or social relationships. The study suggests a strong maternal influence on chimp behavior, with young chimps learning the behavior from their mothers and continuing it into adulthood.
A new study by Brigham Young University researchers may lead to a more accurate system for early detection, diagnosis, and treatment of prostate cancer. The computer model uses medical images to reproduce the growth patterns of prostate cancer on the anatomy of a patient's prostate.
Researchers found that intact nitrogen-fixing symbiosis is necessary for taxonomically diverse and distinctive bacterial communities in legumes. This symbiotic relationship allows legumes to thrive in limited nitrogen environments and may also benefit non-legume plants.
Researchers found a mathematical relationship between life expectancy and the convergence of ages at death, observed in various countries, historical periods, and populations. This rule suggests that fewer people are dying prematurely and living beyond average age of death as life expectancy rises.
Kaspari's research explores the role of sodium in accelerating animal activity and abundance across different ecosystems. He has discovered how chemical elements like phosphorus and nitrogen shape ecological phenomena, from bison herds to termite damage.
A new study of 16 research papers reveals natural regeneration can boost biodiversity conservation and ecosystem services in tropical regions. The method, which is cheaper than traditional reforestation, has social benefits for human livelihoods but requires careful consideration of ecological factors.
A study published in the Canadian Medical Association Journal found that combining dabigatran with two commonly prescribed statins, lovastatin and simvastatin, increases the risk of bleeding. The risk is higher than other statins, suggesting a clinically important drug interaction.
Researchers at the University of Texas MD Anderson Cancer Center have discovered a link between the Golgi apparatus and lung cancer metastasis. The study found that targeting certain proteins in the Golgi can prevent tumor cells from spreading, offering a new potential therapeutic approach for preventing metastasis.
Researchers have developed a new method to track ocean temperature changes using internal tidal waves, which can be detected through satellite data. This approach is cheaper and more reliable than existing methods, allowing for long-term monitoring of ocean warming without harming marine mammals.
Researchers at Saarland University and CISPA create 'vatiCAN' software to secure CAN bus communications in vehicles. The software authenticates messages, preventing hackers from masquerading as legitimate devices or forging information.
A new study combining dozens of existing researches predicts how ocean acidification will impact marine habitats like coral reefs, seagrasses, and kelp forests. The results show that these habitats are vulnerable to acidification, with potential declines in species diversity and complexity.
A new study found that 10-50% of iceberg melting occurs in Greenland's fjords, outweighing the amount of freshwater coming from the island's glaciers. This discovery could help scientists better understand how Greenland melts and its impact on ocean circulation and climate.
Researchers found that cement manufacturing emits significant CO2, but also gradually reabsorbs it through a process called carbonation, reducing its overall impact on climate change. Over 76 billion tons of cement were produced between 1930 and 2013, with an estimated 38.2 gigatons of CO2 released.
GFlow is a computational software that makes wildlife habitat connectivity modeling vastly faster, more efficient and superior in quality and scope. It can solve ecological problems spanning large landscapes and predict the spread of diseases like Zika.