A USC study found that improved air quality in the Los Angeles region has led to a significant reduction in respiratory symptoms among children, including bronchitic symptoms. The study tracked 4,602 children over 20 years and found a 16-32% decrease in these symptoms, even among those without asthma.
A study published in JAMA found that a multifaceted quality improvement intervention involving daily checklists and clinician prompting did not reduce in-hospital mortality among critically ill patients in ICUs. The intervention improved adherence to guidelines, reduced infections, and clinical outcomes, but its impact on mortality was...
Scientists have discovered a predictable trend in the evolution of bird shape among island birds, with flying birds adapting smaller flight muscles and longer legs. This adaptation is driven by relief from predators, rather than genetic divergence.
Researchers have used powerful computers to analyze the decay of calcium-48, a rare isotope that could reveal the mass of neutrinos. The study suggests the decay may be half as long as previously thought, improving chances of detection in underground labs and potentially confirming Majorana particles.
The AGS Annual Scientific Meeting presented numerous high-profile sessions and symposia focusing on de-prescribing medication in older adults, improving interprofessional team communication, and strategies to reduce cardiovascular outcomes in skilled nursing facilities. Bench research findings from 2015 will be applied to bedside care ...
A Finnish group found that vascular endothelial growth factor B (VEGFB) can increase the density of adipose tissue vasculature, reducing inflammation and improving insulin function. Blocking the VEGFR1 receptor enhances the treatment effect by stimulating catabolic processes in adipose tissue.
Scientists have discovered a nuclear receptor protein, estrogen-related receptor γ (ERRγ), that enables the maturation of human beta cells in vitro. This breakthrough overcomes a major challenge in diabetes research and holds promise for creating functional insulin-producing cells at will.
The Cary Institute of Ecosystem Studies will conduct a five-year study in Dutchess County, New York, to reduce Lyme disease risk. Researchers will target feeding and questing ticks using commercially available products, aiming to make neighborhoods safer.
A four-year study found substantial differences between fetal and newborn dolphins in the Gulf of Mexico affected by the Deepwater Horizon oil spill. The researchers identified lung abnormalities and small size among stranded perinatal dolphins, suggesting they died in the womb or shortly after birth due to exposure to petroleum products.
A new study by Giorgi Chaladze uses a computational model to explain the persistence of male homosexuality throughout history and cultures. The research suggests that many heterosexual men carry genes predisposing them to homosexuality, which helps maintain its stability within populations.
Researchers in China have developed a portable laboratory and topography meter to measure the frequency of random landslides on the steep slopes of the Loess Plateau. The system allows for site-specific tests, such as simulated rainfall, and can digitally reconstruct the slope's behavior under erosion conditions.
A new biotherapy has been developed to stimulate the creation of new lymphatic vessels in the heart, reducing oedema and inflammation. This innovative approach has shown significant promise in improving cardiac function following a myocardial infarction.
A doctor warns that many Europeans are denied access to healthcare, with two-thirds of migrants having no access and four in five unable to see a GP. The doctor calls for governments to honour their humanitarian obligations and provide care to those in need.
A recent study published in The BMJ found that replacing saturated fats with vegetable oils rich in linoleic acid does not curb heart disease risk or help people live longer. Despite lowering cholesterol levels, participants who had greater reductions in blood cholesterol actually had higher risks of death.
Researchers at UC San Diego School of Medicine are establishing an interdisciplinary center to define the systems biology of antibiotic resistance, a pressing global medical challenge. The program aims to develop new strategies for treating antibiotic-resistant infections by combining experimental and computational methods.
A 1917 glass plate from the Carnegie Observatories' collection shows the first-ever evidence of a planetary system beyond our own Sun. The plate's spectrum revealed heavier elements, such as calcium and iron, which were expected to have disappeared into the star's interior due to their weight.
A recent study by Lund University researchers found a clear connection between global economic development and increased greenhouse gas emissions. The study analyzed data from 138 countries and discovered that as countries become wealthier, their environmental sustainability decreases.
Researchers have developed a new model of molecular transport using synthetic nanomotors on biopolymer filaments, effectively delivering substances such as anti-cancer drugs. The study's findings suggest that even small motors can operate efficiently without tumbling and losing direction.
Research from Georgia State University suggests that international college students, particularly females, are less at risk for violent victimization due to lifestyle choices and activities. Female international students were found to be significantly less likely to be victims of violent, non-sexual crimes.
The Brain & Behavior Research Foundation has awarded $3.9 million in NARSAD grants to 40 mid-career scientists from 30 institutions worldwide to support basic research, new technologies, and next-generation therapies for schizophrenia, major affective disorders, and other serious mental illnesses.
A new malaria vaccine, RTS,S/AS01, has been developed to combat the disease. Despite waning efficacy in infants and young children, researchers argue that the vaccine could still be used in targeted strategies to interrupt transmission in low-endemic areas.
Research by Michigan State University found that large-scale swine farms in China and the US are breeding ground for multidrug-resistant bacteria. Partner genes, which can confer resistance to multiple antibiotics, were discovered in Chinese soils and manure, highlighting the need for prudent agricultural antibiotic use.
A new University of Iowa study shows that telehealth can help parents with children on the autism spectrum address challenging behavior at a lower cost. Specialists can train parents in applied behavior analysis via computer, reducing travel expenses and staff hours.
Researchers at Helmholtz Zentrum München have identified two variants of the protein MALT1, which are regulated by posttranscriptional splicing and affect the immune response. The study found that stronger activation of T cells is associated with the MALT1A variant, while the MALT1B variant results in a weaker response.
Dr. Peter Adamson, a pediatric oncologist at CHOP, joins the Blue Ribbon Panel of scientific experts advising the VP's initiative on cancer research goals and approaches.
A research team captured unique video of thousands of red crabs swarming in low-oxygen waters just above the seafloor off Panama. The crabs were identified as Pleuroncodes planipes and represent a new southernmost range for the species.
Researchers are often hesitant to discuss shame, using terms like ostracism instead, according to UC Santa Barbara researcher Thomas Scheff. Scheff argues that conventional thoughts about shame see it as an emotion triggered by a particular stimulus, but he believes humans are built around shame and it's time to reclaim the term.
Researchers from ITMO University have developed a novel approach to constructing quantum communication systems, enabling the transmission of single-photon quantum signals across distances of up to 250 kilometers. The system uses side frequencies to simplify device architecture and increase pass-through capacity, making it comparable to...
A collaborative collection development platform called Cobweb is proposed to support comprehensive web archiving by coordinating independent activities of the web archiving community. The platform will leverage existing tools and sources of archival information to retrieve holdings data from over 3,500 collections across 350 institutions.
Human ancestors adapted to fire-prone environments by exploiting its foraging benefits, improving search and handling efficiency. This scenario provides a solution to the mismatch between fossil and archaeological records.
The Institute for In Vitro Sciences (IIVS) hosted a unique 2.5-day workshop on in vitro exposure systems and dosimetry assessment tools for inhaled tobacco products. Attendees gained a deeper understanding of the issues involving aerosol exposure to cells and tissues in culture.
Researchers have identified a range of neurological and psychiatric symptoms in Ebola survivors, including vision complications and joint pain. The study's findings highlight the need for improved treatment options for those affected by post-Ebola syndrome.
A study found that only 37 countries provide low-risk drinking guidelines, with inconsistent standards and varying definitions of a standard drink. The size of a standard drink varies by 250%, from 8g in Iceland to 20g in Austria.
Researchers analyzed previously unpublished data from a large controlled trial and found that using vegetable oils high in linoleic acid may not decrease the risk of heart disease. In contrast, using butter did lower cholesterol levels without affecting heart attacks or deaths.
A new study reveals a mechanism involved in lymphangiogenesis, specifically in corneal transplants and infectious eye disease, by inhibiting the overgrowth of lymphatic vessels. Galectin-8 promotes pathological lymphangiogenesis, increasing the risk of organ rejection and cancer metastasis.
Researchers found that depression combined with metabolic risk factors significantly increases the risk of developing type 2 diabetes. The study suggests a vicious cycle where depression and metabolic symptoms exacerbate each other, making integrated treatment crucial for prevention.
A study found that older black women are less likely to receive trastuzumab, a targeted drug improving survival by nearly 40%, than white women. Approximately half of women in the study did not receive any therapy, highlighting disparities in access to proven yet expensive treatment.
Researchers analyzed data and samples from 364 patients with acute skin rash, detecting ZIKV RNA in 119 blood samples. The study found the virus was introduced to Brazil from Asia, with at least some cases transmitted locally through mosquito bites or person-to-person contact.
Researchers discovered a superfast wing muscle in tropical birds, which can move at speeds of over 60 Hz, faster than any animal with a backbone. This adaptation allows birds to perform extravagant courtship displays without sacrificing flying ability.
Scientists propose a two-stage model of consciousness processing, where the brain analyzes features continuously and unconsciously before rendering them conscious. The process lasts up to 400 milliseconds, with no consciousness in between.
A recent study found that seniors use Facebook primarily for social bonding and curiosity, with a desire to stay connected to family and friends. The researchers suggest that simple and convenient interface tools are essential for attracting older adult users and motivating them to use the site longer.
A large study of 43,313 women found that infertility and hormone treatment may be linked to higher breast density, a known risk factor for breast cancer. The association was strongest among women who had undergone controlled ovarian stimulation (COS), a common fertility treatment.
Gloria Heppner's 1984 article "Tumor Heterogeneity" has stood the test of time, cited more than any other article in Cancer Research history. The article's longevity is attributed to its clarity and interpretation of data, making it a landmark in cancer research.
Research suggests that children of older mothers are healthier, taller, and more educated than those born to younger mothers. Despite the risks associated with advanced maternal age, the benefits of delaying childbearing may outweigh these risks due to improvements in public health and social conditions over time.
Researchers found that concussions in young children can lead to a decline in their social interactions with parents. The study aimed to assess the quality of parent-child relationships six months after injury.
Researchers at Carnegie Mellon University have identified specific neural systems used to encode new scientific concepts. The study shows that the brain repurposes existing neural structures to form new knowledge, enabling humans to learn abstract ideas.
A study in Southern California found significant reductions in bronchitic symptoms among children due to decreases in air pollution levels. The analysis of 4,602 children aged 5-18 years revealed a proportional association between improved air quality and decreased respiratory issues, particularly among those with asthma.
A study by KU Leuven researchers found that more than 70% of cloud-based security providers' DNS redirection strategies can be bypassed, exposing websites to DDoS attacks. To mitigate this risk, website owners can adjust their firewall settings or change their IP address once the contract with the provider is initiated.
Scientists at Oxford University have identified biomarkers that could indicate TB risk and provide clues to assess the effectiveness of potential new vaccines. The discovery was made using immune correlates, also known as biomarkers, which can be measured in the blood.
Researchers from Duke University demonstrate that oxygen levels in coal ash disposal sites greatly impact the leaching of toxic selenium and arsenic. The study suggests that ignoring oxygen conditions when closing ash ponds may not be a solution to the problem, and highlights the importance of considering this factor for safe disposal.
Researchers found that users need different workstation components when standing at a computer workstation compared to sitting down. The final standing workstation setups were significantly different from seated workstation setups, with lower desks and monitors, and closer mouse and keyboard positions.
A research team confirms that 97% of climate scientists agree human-caused climate change, with expertise being the primary factor in this consensus. The study drew from seven independent consensus studies and found a consistent picture with high levels of scientific agreement among climate experts.
A new study published in Nature Communications proposes that the spread of sexually transmitted infections (STIs) and peer pressure drove the emergence of social norms favoring monogamy. As populations grew, STI prevalence increased among polygamist networks, making monogamous mating more advantageous.
Research from Oregon State University shows that toddlers with mobility disabilities spend less time engaging in play and physical activity compared to their peers. Modified ride-on toy cars can help increase interaction with peers and objects, providing essential developmental benefits.
A new study simulates climate change effects on Rocky Mountain stream systems, finding that warmer temperatures have a greater impact on streamflow than changes in precipitation type. This can lead to reduced streamflow and altered groundwater recharge patterns.
Researchers have identified a core component of a conotoxin from marine snail venom that retains its pain-relieving properties after simplification. This modified conotoxin successfully treated pain in a laboratory rat model similar to human irritable bowel syndrome.
Researchers at Umeå University found that mutations in the SAMHD1 protein lead to an imbalance of DNA building blocks and increased mutation rates in colon cancer cells. This discovery suggests that changes in dNTP levels may contribute to the development of colon cancer.
Salk researchers have found a hidden energy switch that powers up pancreatic cells to respond to glucose, enabling the production of functional human beta cells. The breakthrough could lead to a viable treatment for type 1 and 2 diabetes.
FACETS, Canada's first open access science journal, has launched with a broad scope encompassing six major research fields and over 30 subjects. The journal waives article processing charges for submissions by June 30, 2016, to foster open access publishing and advance scientific knowledge.
Mathematicians and physicians at the University of Bonn have developed a new model for immunotherapy of cancer. The method describes how tumor cells change their external appearance in response to treatment, making it difficult for T-cells to recognize them as harmful.
A new study has identified potential health risks for healthcare professionals performing x-ray guided cardiovascular procedures due to radiation exposure. The research found that workers with higher radiation exposure were at increased risk of developing orthopedic problems, cataracts, and cancers.
Testosterone therapy appears to be safe in the short term, with benefits including improved well-being, decreased gender dysphoria, and reduced breast cancer risk. However, potential undesired effects include acne, alopecia, and increased blood pressure.
A recent study found that a droplet hitting a thin fiber will be captured at low speeds, pass through at intermediate speeds, and split at high speeds. The researchers' model has significant implications for optimizing water collection systems and fiber-coating technologies.
Researchers at Numenta Inc. have published a new theory on how networks of neurons in the neocortex learn sequences, providing a breakthrough in understanding neural circuits.
Researchers create a deformable lens array that adapts to the sheet camera's curvature, producing high-quality images over a wide range of deformations. This innovation could lead to cameras the size of a credit card or wrapped around everyday objects.
Research found that acknowledgment of responsibility and offer of repair are crucial elements in an apology, with expression of regret, explanation of what went wrong, and declaration of repentance tied for third effectiveness. The study also showed that the request for forgiveness is the least important component.
The study uses coarse-grained modelings to probe multi-scale behaviors in heterogeneous materials, revealing dynamical similarities, invariants, and slow-varying quantities. The researchers develop new approaches to analyze complex structures and fields, leading to a deeper understanding of the underlying mechanisms.
The Alzheimer's Association has developed recommendations for patient care milestones, including workforce development, timely diagnosis, education, and care guideline measures. Caregiver support strategies include culturally sensitive training, enabling caregivers to balance care with their own well-being, and addressing housing needs.
A new study found that low-risk drinking guidelines differ significantly across countries, reflecting varying attitudes towards alcohol consumption. Different countries assign distinct daily or weekly limits for men and women, leading to confusion among researchers and the public.
A new Bt technology could provide improved control of thrips and plant bugs in cotton, reducing the need for insecticide applications. The treatment has shown better plant protection than alternative strategies in field tests.
A simulation study found that coordinated efforts can prevent over 75% of CRE infections in healthcare facilities. The CDC has issued a toolkit to assist with planning and communication.
A study found that physicians incorrectly believe FDA approval requires comparable effectiveness and strong evidence, leading to inadequate communication with patients. The 'breakthrough therapy' designation has been misinterpreted by many medical professionals.
A new study finds that early treatment for post-traumatic stress disorder (PTSD) significantly reduces symptoms, but does not prevent long-term suffering. The research suggests that prolonged exposure and cognitive therapy can shorten the recovery time, but may not reduce PTSD prevalence.
Researchers discovered that entire sets of maternal and paternal chromosomes can segregate into different cells in embryonic development, leading to chimeric embryos. This finding provides a new mechanism for chimerism and may improve embryo selection approaches for IVF preimplantation genetic diagnosis.
A new Duke University-led study uses mapping software to track threats to endangered species, pinpointing areas for conservation. The San Martin titi monkey's habitat has been fragmented due to farming, logging, and urbanization, with nearly 95% of remaining habitats too small or poorly connected to support viable populations.
Research shows people with type 2 diabetes are more susceptible to non-alcoholic fatty liver disease (NAFLD), a condition characterized by a build-up of fat in liver cells. The study found that hospital admissions and deaths caused by liver disease are likely to rise if cases of type 2 diabetes continue to increase.
Researchers will investigate stress management interventions for chronic pain and illness, including cardiovascular disease, diabetes, and HIV. The study aims to improve disease-related biomarkers, treatment adherence, health behaviors, and psychological outcomes.
A preliminary study found that clemastine fumarate partially reversed optic nerve damage in people with MS. The drug improved transmission signal times by an average of 2 milliseconds per patient, suggesting possible myelin repair.
Researchers at Rush University Medical Center are conducting a five-year randomized trial to test the MIND diet's effects on cognitive decline and Alzheimer's disease incidence. The study will enroll 600 individuals aged 65+ and evaluate the diet's impact on brain structure, cognition, and health outcomes.
Simulating CO2 saturation in rocks could provide a breakthrough in carbon capture and storage by estimating the rocks' potential locations. Researchers at Kyushu University have developed a technique to characterize fluid displacement processes, allowing for more accurate estimation of storage capacity and leakage risk.
Tropical Cyclone Fantala has developed with a 15 nautical-mile-wide eye and strong thunderstorms circling the low-level center. The storm is intensifying rapidly as it moves west toward Madagascar, with projected peak winds of 120 knots (138 mph/222 kph) after three days.
Programs to prevent inappropriate medication use, reduce unnecessary medical procedures, and link vulnerable adults to Medicare are highlighted at the AGS16 meeting. These initiatives aim to improve quality of care and address population growth needs for older adults.
Researchers at Moffitt Cancer Center discovered that liver metastases derived from colorectal tumors are more resistant to radiation therapy. The study found that gastrointestinal stromal tumors were the most resistant, while those from breast and lung cancers were more sensitive.
Researchers at Penn State College of Medicine have discovered a potential target for treating lupus: interferon gamma. The cytokine stimulates immune cells and is involved in the formation of autoreactive B cells that produce autoantibodies, leading to inflammation and tissue damage.
A study by University of Cambridge researchers used Foursquare and Twitter data to quantify the social diversity of London neighborhoods, discovering that signs of gentrification are strongest in deprived areas with high social diversity. These areas saw an influx of more affluent visitors and improved wellbeing indicators.
Researchers created knockout mice that lack a gene involved in DNA repair, shedding light on how cells fix broken DNA. The mice developed kidney and liver dysfunction due to impaired detoxification, highlighting the importance of FAN1 protein.
UM College of Arts & Sciences psychology researchers found associations between specific dopamine genes and initiating joint attention in high-risk siblings. Early levels of joint attention have been linked to later ASD symptoms, suggesting that dopamine genes may help explain differences in early communication.
A mobile-phone-based system is demonstrating huge potential for improving public health service delivery in resource-poor settings. The system has facilitated ongoing data collection, greatly improving data quality, timeliness, and cost-effectiveness.