A Georgia State University biologist has received a four-year, $1.37 million grant from the National Institute of Health (NIH) to study epigenetic mechanisms and their link to obesity. The researcher aims to induce brown adipocytes in white fat tissues to prevent and treat obesity.
New research from NC State University demonstrates that experts can use air sampling technology to detect and quantify radiological releases. The technique was tested using data from the 2014 WIPP nuclear facility accident, achieving impressive accuracy and precision.
A study found that adolescents who slept only five hours a night for seven nights experienced significant cognitive degradation, including decreased sustained attention and working memory. Even after recovery sleep, residual effects persisted.
Researchers are launching a controlled experiment in four area school districts, introducing school gardens and nutrition and cooking classes for high-risk students. The program aims to improve dietary intake and reduce obesity and metabolic risk, with promising effects seen in an earlier pilot study.
The UT Health Science Center at San Antonio's UltraScan software helped confirm the structure of a protein complex that enables viral infection, as reported in a recent Nature publication. The technology utilizes advanced coding and analytical ultracentrifugation to deliver sophisticated biological metrics.
Engineered fabrics effective against superbugs like MRSA could reduce impact of super-bacterial infections. Researchers have successfully produced anti-super-bacterial masks using violacein-based dye, blocking growth by 99.9%.
Research predicts an earlier start to spring growing season and warmer winter temperatures in North American grasslands, partially offsetting negative effects of higher summer temperatures. Annual productivity is expected to increase despite drought-induced reductions in summer productivity.
Scientists have identified a spectrum of genetic alterations, including some that may be clinically actionable and others that could improve diagnostics and screening for patients. The study's findings suggest targeted therapies and immunotherapies could be effective treatments for mesothelioma.
A University of Leeds study reveals EU policies have reduced air pollution across Europe, preventing an estimated 80,000 premature deaths per year. The findings demonstrate a 35% decrease in fine particles since 1970, significantly improving public health.
Researchers warn about the limitations of microsatellites in genetic diversity studies, highlighting the importance of sequencing flanking regions to minimize homoplasy. The study's findings suggest that using markers designed for a different species can lead to inaccurate conclusions.
Research reveals that dopamine regulates both rewarding and aversive behaviors in mice, enabling them to learn and remember to avoid negative situations. The study's findings have implications for understanding post-traumatic stress syndrome.
The Canadian Medical Association Journal urges that public health be involved in the upcoming inquiry into missing and murdered Aboriginal women. The root causes of interpersonal violence and health disparities are linked to a legacy of colonization, cultural genocide, and societal neglect, Dr. Kirsten Patrick explains.
Researchers at Hiroshima University have identified two molecules, HMGB1 and MMP-9, involved in maintaining nerve pain after injury. Blocking these molecules alleviated pain in mice without negative effects on healing.
A study published in The Journal of Experimental Medicine found that hyper-aggressive immune cells that consume glucose may drive the development of coronary artery disease. Blocking this glucose overconsumption prevented inflammation and atherosclerosis, suggesting new therapeutic interventions to prevent heart attacks.
Researchers from the Virtual Planetary Laboratory have identified biosignature impostors, which can masquerade as signs of life on exoplanets. By detecting these 'false positive' cases, scientists can avoid misinterpreting oxygen signatures in planetary atmospheres.
Osteoporosis medications bisphosphonates have significantly reduced fracture risks but also increase the risk of atypical femur fractures. Treatment involves stopping the drug and supplementing with calcium and vitamin D.
The study confirmed the role of known genes, ruled out others and identified a new gene associated with strokes caused by large artery atherosclerosis. The research found that each identified gene is associated with a specific stroke subtype, suggesting a need for subtype-specific risk factor investigation.
Researchers found a temporary increase in ischemic stroke rate after daylight saving time transitions, with people with cancer and over 65 at higher risk. The study suggests disruptions in circadian rhythm may contribute to the increased risk, but further studies are needed to understand the relationship.
Researchers discovered a new species of threespine stickleback in Lake Constance that diverges rapidly, even when breeding alongside other populations. This finding challenges traditional speciation theories and highlights the importance of genetic analysis in understanding evolutionary processes.
Lawrence Livermore National Laboratory researchers developed a simulation to predict the permeability of drug molecules across cell membranes, enabling faster testing and development of nerve-agent treatments. The simulation shaved weeks off compound testing, reducing the time required from six weeks to just 16 hours.
A new one-atom-thick flat material made of silicon, boron, and nitrogen has been discovered by University of Kentucky physicist Madhu Menon. The material is extremely stable, a property lacking in many graphene alternatives, and can be fine-tuned to suit various applications.
A team of researchers found that squid suckerin proteins are composed of beta-sheet polymer networks, giving them strength and stretchiness. These thermoplastic proteins could be used to create biomaterials for tissue growth and artificial ligaments, offering a sustainable alternative.
Researchers found that osteopathic manipulative treatment (OMT) significantly improved symptoms in patients with moderate to severe low back pain, reducing disability by up to 50%. The study suggests OMT as a viable alternative to surgery for these patients.
A study found that patients with inflammatory bowel disease and a history of cancer did not experience a significant increase in cancer risk when treated with anti-TNF therapy. In fact, 96% of patients were still alive and cancer-free after one year.
Researchers at MIT have developed a general theory that connects gravity waves and acoustic waves, finding that surface-gravity waves can generate powerful acoustic-gravity waves under certain conditions. This energy exchange could play a role in water transport, carbon dioxide distribution, and sustaining a healthy marine environment.
A study by UCSB psychologists found that challenging a person's belief in free will corrupts intuitive cooperation and leads to impulsive selfishness, but allows for recovery with time. Participants who were asked about their agreement with the statement 'I have free will' showed significant differences in their level of cooperation.
A new clinical trial has begun at Oxford and Sheffield to test a potential vaccine for prostate cancer. The vaccine aims to stimulate the immune system's attack on cancer cells by recognizing a specific protein found on their surface. If successful, future studies will assess its effectiveness in preventing disease progression.
A new study led by Stanford University researchers found that the number of surgeries performed worldwide has grown, yet there remains a huge gap in surgical care between rich and poor nations. The most frequently performed operation in poor countries was cesarean section, suggesting other significant surgical needs are being given low...
A recent study found that Fitbit-Flex is a valid and reliable device for monitoring physical activity, particularly in cardiac patients. The device accurately tracks step counts and minutes of moderate to vigorous physical activity, making it a valuable tool for clinicians and researchers.
Researchers found that test subjects followed a faulty robot's instructions during an emergency simulation, suggesting people trust robots too much. The study aims to understand human-robot trust and develop safer robots for emergency situations.
A single dose of trastuzumab kick starts an immune response in certain HER2-positive breast cancers, with women having the highest rate of immune response being those with the HER2-enriched subtype. The immune-cell-activating properties of trastuzumab are likely related to the subtypes of breast cancer.
Researchers at the University of Bath created a new type of laser that can emit mid-infrared light between 3.1 and 3.2 microns, a range previously difficult to achieve. The breakthrough uses silica hollow-core fibers to confine light and enable gas-mid-IR interaction.
A new study found that students who attend schools with programs and policies supporting LGBTQ youth are less likely to binge drink, regardless of their sexual identity. Living in states or cities with more affirmative school climates was associated with fewer binge drinking days for gay/lesbian and heterosexual students.
A study of 120,000 women found five genetic variants affecting breast cancer risk, which alter how cells respond to oestrogen. The variants are associated with changes in the expression of genes involved in oestrogen regulation, potentially leading to new breast cancer preventions.
A study of over 15,000 people found a 10% rise in older adults developing second or third chronic conditions, while physically active individuals were healthier. The prevalence of multimorbidity increased from 31.7% to 43.1% between 2002/03 and 2012/13.
A new study by SISSA/CNR IOM scientists reduces wastage of expensive catalysts used in fuel cells, allowing for more efficient and sustainable energy production. The researchers created nanoparticles on nanosteps, which remain dispersed and stable, enabling the material to be reused with lower costs.
A study published in the Journal of Adolescent Research found that Asian-American adolescents desire more open discussions about sexual health with healthcare providers. Key themes included confidentiality concerns, a general lack of knowledge regarding STIs and contraception, and hesitation to discuss sexual histories. Providers can a...
A national survey found that most Americans are willing to pay more taxes to support biodiversity conservation in the Gulf of Mexico. The survey showed that people value preserving biodiversity for future generations and are willing to pay between $35 to $107 more annually for the expansion of the Flower Garden Banks National Marine Sa...
A recent study finds that states that opted out of a federal rule requiring physician supervision for anesthesia care did not experience an increase in patient access to this service. In fact, opt-out states showed lower growth rates in anesthesia cases compared to non-opt-out states.
Scientists at Berkeley Lab have developed MIDI-STEM, a new method that improves images of light elements using fewer electrons. This technique allows for high-resolution views of lightweight atoms and materials with a mixture of heavy and light elements.
A Harvard University study finds that grasslands across North America will experience an earlier start to the spring growing season and warmer winter temperatures, offsetting climate change's negative effects. However, this shift in seasonal patterns presents new management challenges for farmers and ranchers.
A three-week observational study at Greenville Memorial Hospital found that placing alcohol-based hand sanitizers in the middle of a hospital lobby floor increased visitor usage by 528 percent. The study also identified demographic factors influencing hand sanitizer use, such as age and group dynamics.
Researchers discovered a 'circadian circuit' in which clock neurons send signals to the central brain areas that regulate activity and sleep. This mechanism allows time information to be transmitted through the brain.
A new software called EaSeq enables biomedical researchers to study and test hypotheses using their own data in a matter of hours. This analytical tool improves the analysis of ChIP sequencing data, which holds potential for clinical applications.
Research by the University of Kent finds that illegal wildlife trade is facilitated by the global internet, but trade on the darknet is surprisingly low. The study suggests that poor enforcement and easy access to online platforms have led to a negligible amount of trade on anonymous networks.
A national free ambulance services programme in rural Ethiopia has seen a drastic reduction in pregnancy-related deaths, with the model potentially paving the way for improved maternal health outcomes across Sub-Saharan Africa.
A new human liver microphysiology platform has been developed to study liver physiology, drug safety, and disease progression. The Sequentially Layered, Self-Assembly Liver (SQL-SAL) model mimics the physiological conditions created by immune, stellate, and endothelial cells.
A new study by the University of Missouri School of Medicine shows that electroanatomical mapping is an effective alternative to fluoroscopy, reducing radiation exposure and improving patient outcomes.
Researchers discovered how small capillaries form during angiogenesis, a process crucial for embryonic development, cancer, and diabetes. Blood pressure drives the membrane of endothelial cells to cave in and grow into the cell's body.
Researchers found that black widow spiders' red hourglass markings are more visible to birds than to insects, helping them avoid detection by predators while still warning off potential prey. This study highlights the complex communication strategies used by animals to adapt to their environments and evade threats.
Research from the University of Exeter and Plymouth Marine Laboratory reveals that plankton ingesting microplastics produce faeces that sink more slowly, allowing plastic to be transported to deeper waters. This process could have significant implications for marine ecosystems and the removal of floating plastic litter.
A study by University of Washington researchers found that doctors struggle to review patients' self-tracked data due to lack of capacity and tools. However, when patients provide organized and summarized data through paper diaries or specific tracking tools, providers can use it effectively in diagnosis and treatment.
Researchers at the University of Illinois discovered that high-protein canola meal is a valuable ingredient in swine diets, offering similar digestible energy and amino acid profiles to soybean meal. The study found improved digestibility of crude protein and amino acids in high-protein canola meal compared to conventional canola meal.
Scientists designed a novel bispecific antibody that selectively blocks overproduction of TNF, a protein harmful when overproduced in autoimmune diseases. The prototype shows promise for treating conditions such as rheumatoid arthritis and Crohn's disease.
Researchers at The Hebrew University of Jerusalem have developed a nanotechnology-based delivery system that activates the body's natural defense against free radicals. This system could control various skin pathologies and disorders by inducing antioxidant enzymes and maintaining skin cell redox balance.
A new method using proton nuclear magnetic resonance (H-NMR) of blood plasma identifies unique metabolic biomarkers for early and late-stage lung cancer. The technique correctly classifies 78% of patients and 92% of controls, showing promise as a complementary tool to improve lung cancer screening.
A longitudinal study of over 6,000 adults found that lower self-rated health and age-related decrements in processing speed are strong predictors of mortality risk. Being a woman and having better perceived health were also associated with reduced mortality risk.
Scientists have developed an illustrated key to distinguish between 41 snout moth grass borers using genitalia analysis. This helps identify economically important pests that feed on crops like sugarcane and corn in the Western Hemisphere.
A small study found significant associations between difficult child behavior and mobile technology use to calm kids down. Parents with less control over their children's behavior were more likely to turn to devices like phones and tablets as a coping strategy.
According to Dr. Dina Krasikova, a confident leader can boost their subordinates' creativity, trust and productivity. A study by UTSA found that leaders who value creativity must set an example themselves, fostering high-quality interpersonal relationships with their team.
The MAVEN mission collected data from a close approach to Martian moon Phobos, providing spectral images of the moon's surface. The observations will help scientists understand the moon's origin, comparing it to asteroids and meteorites.
A new study from French Polynesia found a link between Zika virus infection and Guillain-Barré syndrome, a severe neurological disorder. The study analyzed 42 patients diagnosed with GBS during the Zika outbreak and found that most had symptoms of Zika virus infection before developing neurological symptoms.
The Lung Cancer Master Protocol (Lung-MAP) trial is a groundbreaking collaboration that uses genomic profiling to match patients with promising new treatments. With the addition of nivolumab, an FDA-approved immunotherapy, the trial offers innovative therapies for advanced stage squamous cell lung cancer.
A study by the University of Texas M.D. Anderson Cancer Center reveals that adult stem cells in the prostate basal cell layer express genes similar to those found in deadly prostate cancer, offering a potential new line of treatment for highly aggressive and therapy-resistant forms.
A recent study published in the journal SLEEP found that people with insomnia do not have higher levels of cholesterol than those without. However, insomniacs who take sleeping pills were found to have significantly higher levels of LDL cholesterol.
The research team improved cell voltage by shifting away from a standard processing step using cadmium chloride. This approach enabled the fabrication of CdTe solar cells with an open-circuit voltage breaking the 1-volt barrier for the first time.
The Cyclotron Road program has selected its second cohort of innovators, including researchers working on next-generation batteries, advanced materials, and solar technologies. The new cohort will receive funding and mentorship to develop their technology from Berkeley Lab.
A study found that subcutaneous insulin infusion does not prevent oxidative stress and inflammation in the liver, despite reducing glycemic variability. The therapy also failed to preserve balance of anti- and pro-oxidant species.
Researchers have achieved a new milestone in quantum physics by entangling three particles of light in a high-dimensional quantum property. This breakthrough has the potential to revolutionize quantum encryption and secure communication, enabling multiple parties to share information with unconditional security.
Researchers at Scripps Florida Institute have developed a new method to predict the activity of stem cells in treating various diseases. The Clinical Indications Prediction scale uses TWIST1 levels to determine therapeutic potential, highlighting the importance of considering both angiogenesis and anti-inflammatory effects.
A survey of endocrinologists found that while more education and training have been received on transgender care, self-rated comfort levels remain relatively low. Only 20% were 'very' comfortable discussing gender identity and 41% described themselves as competent to provide transgender care.
Researchers analyzed over 17,000 South Carolina court decisions to find that black offenders are more likely to be jailed and serve longer sentences than their white counterparts. The study highlights racial bias in sentencing decisions, with the 'black penalty' varying depending on an offender's criminal history.
Gene therapy has made significant progress in treating X-linked severe combined immunodeficiency (SCID-X1), with hematopoietic stem cells showing promise for a cure. However, ongoing challenges include improving safety and achieving long-term immune reconstitution, highlighting the need for continued research and development.
Researchers discovered that multi-target antiarrhythmic drugs like amiodarone change cell membrane properties, altering the function of multiple proteins. This finding has implications beyond AF treatment, suggesting a general mechanism for drug-induced changes in membrane protein function.
A multicentre study found type 1 diabetes associated with higher cancer incidence, especially for cancers of the stomach, liver, pancreas, endometrium, ovary, and kidney. Women with type 1 diabetes had a smaller but still significant increased risk compared to men.
Akinori Teramura's Twitter post revealed the first recorded case of illegal bluegill fish release in Japan, sparking concerns about native aquatic insect biodiversity. The researchers concluded that the fish were likely released from an aquarium or home aquarist, highlighting the need for community awareness and improved reporting.
Researchers found that most MOOC instructors face challenges throughout the course development and instruction process, including preparation, implementation, and feedback phases. Instructors reported heavy workloads, overwhelming expectations, and difficulty in providing one-on-one guidance in a large online class.
A fossilized femur bone has revealed the massive size of an abelisaur, potentially one of the largest ever found. The discovery helps researchers determine the maximum sizes these dinosaurs may have reached during their peak.
Scientists at VIB discover that mutations at specific positions can suppress protein aggregation, increasing solubility. This breakthrough could enable the production of protein drugs and enzymes with improved stability and functionality.
Men with low-grade prostate cancer are increasingly opting for active surveillance, a management strategy that monitors the cancer's progression without immediate treatment. The study found that about 59% of patients managed by active surveillance remained on this approach after five years.
A study published in SLEEP found that sleep deprivation amplifies the joy of eating, particularly sweet and salty high-fat snack foods. Sleep-restricted participants ate nearly twice as much fat as those with normal sleep, despite minimal energy needs.
A new NYU study reveals that three out of four top reasons urban farmers grow crops are driven by social motivations, including food security, education, and community building. The research also finds that many urban farms operate as nonprofits, shifting financial focus from sales to donations and grants.
Researchers at Cornell University discovered that bone can recover its shape after breaking, unlike most man-made materials. This unique property allows cancellous bone to direct cracks to less detrimental locations, enabling it to bounce back after a fracture.
A University of Colorado study reveals a weak link between MN1 and aggressive AML, suggesting EPZ-5676 as a potential tool to break this link. The drug inhibits chromatin regulators Mll1 and Dot1l, which are essential for MN1's leukemia-causing effects.
A new study found that people without cardiovascular disease in their 80s are more likely to develop dementia. Researchers also discovered a link between low levels of artery-clogging calcium deposits and a lower risk of dementia.
Researchers found that wealthier seniors in Ontario were prescribed a new blood thinner more often than poorer seniors, but access improved when the drug was covered by publicly funded plans. The study highlights socioeconomic barriers to accessing new medications and calls for timely reimbursement decisions by provinces.
The University of Pennsylvania School of Nursing will fund the scholarship of five doctoral nursing students in 2016 thanks to a $60,000 grant from the Jonas Center. This is part of a national initiative to support 1,000 nurse scholars across all 50 states.
The risk of catching Ebola from a survivor is very low, with most body fluids cleared within weeks apart from semen. Studies found that infected blood is the most infectious, but social contact poses little risk.
A 54.5 million cubic meter snow avalanche occurred in western Colorado, killing three people. The study used large-scale field mapping and seismic signals to analyze the avalanche's movement phases, shedding light on rock-avalanche modeling and ongoing hazards.
Researchers at The Pennsylvania State University College of Medicine discovered that the nuclear export of the opioid growth factor receptor (OGFr) is CRM1 dependent. OGFr must translocate into the nucleus to facilitate its role in cell cycle regulation and does so utilizing nuclear localization signals and β and Ran proteins.
Researchers at The University of Texas at Arlington found that stable environments like constant predator threats induce trans-generational responses in offspring. Water fleas from populations experiencing intense predation developed faster to enhance survival rates in future generations.
The new NIST method uses nonlinear acoustic measurements to detect cracks in ceramic capacitors before they cause electrical failure. This approach has shown promise in rejecting over 90% of sample capacitors with visible cracks and may help prevent failures in medical implants, spacecraft, and other mission-critical electronics.
A recent study found that when people rate the attractiveness of gender-blended face morphs, they tend to judge them as less appealing if initially classified by gender. However, this effect only occurs when people are asked to categorize the face by gender before being shown the blended image
A Swedish study found that approximately 5% of children aged 0-11 years snore several times a week, with only one-third receiving medical help. Children with persistent snoring often experience reduced quality of life, including daytime tiredness and learning difficulties.
Researchers developed a versatile platform for nanoscale thermal measurements using magnetic resonance, optical, and atomic force microscopy. The technique provides nanometer-resolved thermal conductivity maps and can be used to investigate heat flow in nanostructures and catalytic exothermal reactions.
Dr. Ekaterina Dobryakova will explore factors associated with disabling fatigue among individuals with Multiple Sclerosis (MS) using a non-pharmacological intervention. The study aims to identify an endogenous factor that can alleviate cognitive fatigue, which would be a revolutionary development in MS rehabilitation.
Duke University researchers have engineered microbes that can't run away from home; those that do will quickly die without protective proteins produced by their peers. The system could be used to reliably program colonies of bacteria to respond to changes in their surrounding environment, such as releasing specific molecules on cue.
Loss of major histocompatibility complex I (MHCI) expression in motor neurons leads to vulnerability to ALS astrocyte toxicity. Studies show that increased MHCI expression is protective against astrocyte-induced death, providing a potential translational target for ALS treatment.
Researchers estimate that the world can emit even less greenhouse gases than previously estimated if global warming is to be kept under control. The study suggests a carbon budget of 590-1240 billion tons of CO2 from 2015 onwards to limit warming to below 2°C.
A special issue on ocean acidification is published by ICES Journal of Marine Science, exploring various effects and interactions with other environmental drivers. The issue features studies with both negative and no significant effects, promoting a broader understanding of the complex mechanisms involved.
A breakthrough study sponsored by the Office of Naval Research (ONR) Global has significantly boosted the memory and mental performance of laboratory mice through Transcranial Direct Current Stimulation (tDCS). The researchers observed improved performance in navigating a water maze and distinguishing between known and unknown objects,...
A University of Louisville cardiologist is conducting a study to determine if certain lipids in blood can be used to identify women at risk for a heart attack. The presence of oxidized phospholipids may allow doctors to pinpoint women with increased risk before permanent damage occurs.
Researchers at Sam Houston State University developed a test to individualize marijuana samples using DNA analysis, linking drugs across cases. Pine pollen has also been found to be a viable source of DNA for criminal investigations, persisting on clothing for up to two weeks and helping link suspects or victims to locations.
A study published in the Journal of Experimental Child Psychology found that pre-school children prefer to share with a friend who already has an abundance of stickers than with a stranger. The results suggest that social relationships take precedence over fairness as a motivation for sharing behavior.
A study published in Nordic Psychology suggests that ageism can have a significant impact on lifespan, regardless of age. Negative attitudes towards aging are linked to a shorter lifespan, highlighting the need for awareness and debate about this complex issue.
A new study by NOAA and CIRES scientists reveals that the US is responsible for 8% of global CCl4 emissions, with hotspots in the Gulf Coast region and Colorado. The findings contradict previous reports and highlight the need for further research to understand the source of excess emissions.
Researchers found preserved Siberian moose with distinct DNA features in Western Siberia, providing insights into the region's genetic history and potential as a refugium for forest species. The discovery sheds light on the moose's evolutionary past and its adaptation to changing environmental conditions.
Researchers found that patients with lung and colorectal cancer who had financial distress at diagnosis reported significantly increased pain, symptom burden, and poorer quality of life. The study highlights the need for clinicians to target resources and treatments for patients struggling financially.
A study published in Scientific Reports found that writing a message to the perpetrator can disrupt the chain of unfair behavior, calming negative emotions and leading to fairer interactions. The researchers suggest this strategy as a way to stop the spread of injustice.
Researchers developed a new method called PRISM to test potential drug compounds on cancer and other cell lines simultaneously, allowing for pooling and testing of multiple cell lines. This approach promises to accelerate the search for targeted therapies by better representing the broad genetic diversity of disease.
Researchers found that female mice with a mutated ITCH gene had reduced implantations and corpora lutea, as well as extended estrous cycles. The study suggests a potential role for ITCH in regulating reproductive function.
A study led by SUNY Downstate Health Science University found increased risk of obesity among Filipino immigrants living in the New York City metropolitan area. The findings suggest that prolonged US residency erodes the health advantage initially carried by immigrants, a process known as 'unhealthy assimilation'.
Researchers found that flushing away inflammatory cells contributed to restored memory function in test mice with Alzheimer's disease. The study suggests targeting these cells with specific drugs may be a promising new approach.
Researchers at Helmholtz Munich identified a new component regulating body weight and food intake, with histone deacetylase 5 (HDAC5) playing a significant influence on leptin's effect. The study found that HDAC5 is essential for the brain to recognize fat depot levels, enabling adaptation to food intake and reducing obesity.
Researchers at St. Jude Children's Research Hospital identified an enzyme that aids pneumococcus survival by removing its capsule, making it harder to be detected and destroyed by the immune system. This discovery has profound implications for treatment and vaccine strategies to combat invasive pneumococcal disease.
Research from Purdue University reveals that childhood poverty and parental abuse can lead to a range of adult health issues, including cancer, heart disease, and smoking. The study, based on data from 1,748 adults, found that these early life experiences had a lasting impact on adult health outcomes.
Scientists have developed a systematic approach to discovering unknown DNA modifications, using a combination of bioanalytical chemistry, comparative genomics, and single-molecule real-time sequencing. This approach has led to the discovery of a new epigenetic mark, dADG, which helps bacteria defend their genomes from viral infection.
EPFL researchers have developed conductive tracks that can be stretched up to four times their original length and still maintain conductivity. The new metallic and partially liquid film has a wide range of possible applications, including artificial skin, connected clothing, and on-body sensors.
A new study published in the Journal of Interpersonal Violence found a significant relationship between firearm crime and an increase in concealed-carry gun permits. The research examined county-level data from Florida, which issued over 1.6 million valid concealed-carry permits as of November 2015.
Researchers have discovered a novel role for CD40 antibodies in re-educating macrophages to break down the tumor microenvironment, allowing chemotherapy to target pancreatic cancer more effectively. The optimal timing of delivery is critical, with chemotherapy being most effective when administered five days after CD40 treatment.
A new study from The Ottawa Hospital and the University of Ottawa shows that men with slow-growing prostate tumors are increasingly adopting active surveillance, a monitoring approach that avoids unnecessary treatment. After five years of follow-up, about 59% of patients under active surveillance were still managed that way.
A new study by researchers at Fred Hutchinson Cancer Center suggests that precision oncology could be tailor-made for metastatic prostate cancer. A single metastasis within an individual patient provides consistent molecular information to guide therapy, and patients benefit from individualized treatment.
Researchers at Syracuse University have developed a new energy transfer system that combines nanomaterials and biomaterials to produce bioluminescence. The system, demonstrated in ACS Nano, has high-efficient energy transfer between semiconductor quantum rods and luciferase enzymes.
Researchers estimate that e-cigarettes helped 16K-22K long-term quitters in England in 2014. The use of e-cigarettes increased the chances of success by around 50% compared to traditional nicotine products.
A new study reveals that algal blooms like 'red tides' are home to a complex war between microscopic organisms, with the dominant species changing daily. The research sheds light on the ocean's role in carbon fixation and climate change.
A study published in PLOS ONE suggests that cannabis users have difficulty recognizing and empathizing with human emotions like happiness, sadness, and anger. However, the brain may be able to compensate for these effects when explicitly detecting emotions.
Brown University engineers developed a new technique to understand how cells move through complex tissues, building on mean deformation theory. The algorithm analyzed images of human neutrophils moving through collagen matrices, revealing differences in contractility and rotation between healthy and sepsis models.
A five-year $1-million grant aims to teach people how to protect their brains through exercise, with a focus on African-Americans at elevated dementia risk. The program will include dance-based exercise and lifestyle education, and gather data on brain circuitry, aging, and stress levels.
A study of 1140 pregnant women and their children found that eczema, rhinitis, pet ownership, and age at introducing solid food are associated with different types of food hypersensitivity. A healthy diet was also found to be protective against both IgE-mediated and non-IgE mediated reactions.
Researchers discovered a gene associated with CHARGE syndrome disrupts molecular pathways controlling myelin sheath formation in nerves and bones. The study suggests a potential molecular framework for identifying therapeutic targets to promote myelin regeneration.
Researchers discovered the organic cation transporter CarT is necessary for maintaining histamine levels in fruit fly brains, ensuring normal vision. Disrupting this process led to impaired vision and behavioral abnormalities in flies.
Researchers have discovered a 520-million-year-old fossilized nervous system, providing the most detailed example yet found. The fossil, from southern China, has revealed individual nerves visible for the first time in a fossil of this age.
A GW chemistry professor is leading a team of researchers to identify enzyme inhibitors as possible medications for devastating diseases like malaria and tuberculosis. The five-year, $2.6 million grant will focus on designing small molecule inhibitors that can stop the production of key enzymes necessary for pathogen survival.
A study published in PLOS ONE found a mutation in the APC gene, linked to colon cancer, in an 18th-century Hungarian mummy. The researchers believe that a genetic predisposition to cancer may have already existed in the pre-modern era.
Researchers at the University of Exeter have created a vaccine that offers high-level protection against melioidosis, a bacterial infection that causes pneumonia and sepsis. The new vaccine, which has been tested on mice, holds promise for preventing a disease that affects thousands in tropical regions and is often misdiagnosed.
A study published in the Bulletin of the World Health Organization found that an estimated 312.9 million surgeries took place globally in 2012, with only 30% of operations occurring in low-income countries representing 71% of the global population.