A genetic blood test called NETest measures specific genes in the blood that define and predict responsiveness to PRRT. The test was found to be more than 90% accurate in predicting therapy response and non-response, with 73% of low-grade tumors responding to treatment.
The Diabetes Collaborative Registry has released baseline data showing clinicians adhere to 4 out of 7 diabetes quality metrics. The registry's first presented results highlight areas for improvement in chronic disease management, with low rates of performance on some measures attributed to lack of documentation or true gaps in care.
A quarter of COPD patients are frail but can respond favourably to exercise rehabilitation. Frail patients who completed the programme scored better in measures of breathlessness and exercise performance, with 61% no longer meeting frailty criteria after rehabilitation.
Researchers at Okinawa Institute of Science and Technology Graduate University have discovered a unique copper-silver nanoparticle structure resembling the Japanese glass fishing floats, known as ukidama. The 'ukidama' structure has properties that could be utilized in biomedical devices and nanotechnology.
A study by University of Arizona Health Sciences reveals the existence of 'T memory cells with naive phenotype' that accumulate with aging and respond to persistent viruses. These cells may hold the key to understanding and boosting immunity in older adults, who are vulnerable to infections due to weakened immune systems.
Ross McDougall, a renowned Stanford professor, has been honored with the 2016 Georg Charles de Hevesy Nuclear Pioneer Award for his groundbreaking work in nuclear medicine. With over 160 peer-reviewed publications and three textbooks on thyroid disease, he has made significant contributions to advancing the field of nuclear medicine.
A randomized Phase III study found nearly 81% of patients in the inotuzumab ozogamicin group achieved complete remission, compared to 31-41% with standard therapies. The drug enabled 41% of patients to proceed with stem cell transplants, increasing their chances of a curative treatment.
A recent study published in The Journal of Physiology found that stress during pregnancy and being born with low birth weight can lead to long-term health issues in mothers. The research, led by Jean Ni Cheong from the University of Melbourne, explored the effects of these factors on maternal health after pregnancy.
Peter S. Conti, MD, PhD, receives the prestigious Paul C. Aebersold Award for his groundbreaking work in developing novel diagnostic imaging agents for oncology applications. His research focuses on PET imaging and gene expression, advancing the field of nuclear medicine and molecular imaging.
A UCL-led team of researchers has developed a model that predicts outbreaks of zoonotic diseases like Ebola and Zika based on environmental changes. The model forecasts the number of people affected by Lassa fever to double from 195,125 to 406,725 by 2070 due to climate change and population growth.
Researchers developed PET tracers that can visualize inflammatory disease and evaluate next-generation MS therapies. The study found that the compounds could detect an increase in S1P1 expression in animals with an inflammatory response, suggesting a promising approach for imaging MS and other inflammatory diseases.
A recent study using PET/CT imaging found that the brains of recovering alcoholics have adapted to chemical dependency by significantly hindering metabotropic glutamate receptor subtype 5 (mGluR5) receptors, reducing cravings. This discovery could lead to new targeted drugs to limit receptor activity in patients at risk of relapse.
Researchers developed pretargeted radioimmunotherapy, combining an anti-GPA33 antibody with radionuclide agents to deliver radiation directly to tumors. In mouse models, the technique achieved complete remission of colorectal cancer without collateral toxicity.