Researchers found that young fish reared in eddies grew faster and had a survival advantage compared to those outside eddies. The study's findings suggest that eddies can act as pelagic nursery areas, providing a critical head start for larval fish growth.
A blood test developed by King's College London accurately predicts which depressed patients will respond to common antidepressants. The test identifies biomarkers associated with inflammation, guiding patients towards earlier access to more assertive treatments.
Researchers found that MPs are willing to use a rapid match-making advisory service to access the latest research findings and seek advice from cutting-edge researchers. The EIS could provide a useful complement to existing information services and help ensure decisions are based on reliable evidence.
A novel combination therapy has been found to clear the infection and prevent recurrence of babesiosis up to 122 days after treatment. The study used a mouse model to test the efficacy of atovaquone and ELQ-334, two drugs that work together to attack the parasite's target enzyme.
Researchers at Carnegie Mellon University developed simplified patient-centered consent forms that were equally effective but more engaging than traditional lengthy forms. Video formats also improved comprehension, with participants reporting feeling more engaged in the consenting process.
A new combination of immunotherapy and chemotherapy has shown a remarkable 53% response rate in pediatric neuroblastoma patients, with some tumors shrinking or disappearing completely. Researchers plan to expand the study to include more children, offering hope for a potential cure.
Researchers have designed a new approach to treating B cell malignancies by targeting specific B cell markers with modified T cells. The treatment showed promising results, resulting in complete remission in two patients and stable disease in four others.
Researchers have identified essential aspects of the regulation of the anti-tumor protein p53, with surprising results suggesting that only a few ribosomal proteins are required to maintain nucleolar structure. This discovery has significant implications for cancer research and development of new biomarkers.
A 24-million-year-old record of vegetation trends suggests that humans developed key traits like flexible diets and large brains while adapting to the spread of open grasslands. The study provides a comprehensive timeline for the development of grasses, which were part of human evolution from the very beginning.
Researchers discovered a novel gene, TMEM230, associated with Parkinson's disease that affects neurotransmitter trafficking between neurons. This new link may lead to novel treatments and better understanding of neurodegenerative diseases.
New research suggests that microgrids may not always be economically efficient in regulated electricity markets. The study examines scenarios for adding a microgrid to a vertically integrated utility network, finding that it can increase or decrease economic efficiency depending on cost assumptions and network characteristics. In some ...
The University of Texas at San Antonio's Maximizing Access to Research Centers (MARC) program has received a $1.9 million grant over five years to train 12 undergraduate students per year in UTSA laboratories. The program prepares students for Ph.D. programs and enables them to conduct top-tier research in the biomedical field.
A family-based weight management program improved self-perception among obese children, particularly in terms of athletic ability and physical appearance. The program also promoted positive body image and diversity of body sizes, leading to significant improvements in these areas.
Scientists compared 64 Staphylococcus aureus strains' genomes to develop a comprehensive understanding of the bacteria's virulence and antibiotic resistance. The study revealed that 19% of genes are essential for life, while dispensable genes offer advantages in specific environments.
A randomized controlled trial found that electroacupuncture combined with nighttime splinting improved symptoms of chronic carpal tunnel syndrome. The treatment provided small improvements in disability, function, and pinch strength among patients with mild to moderate symptoms.
Researchers found that Medicare Advantage patients are younger, healthier, and more likely to be black and live in cities than those enrolled in traditional Medicare. They also reported better health outcomes and fewer problems performing daily life activities on their own.
Researchers found that myricitrin can help maintain two key functions of mouse neurons exposed to neurotoxicity, including enzymatic activity and rapamycin complex 1 activation. The study suggests that myricitrin could have a role in preventing neuronal degeneration in Parkinson's disease.
Researchers identify epigenomic changes that contribute to the development of type 2 diabetes in obese individuals. These changes are associated with inflammation and trigger insulin resistance, highlighting the importance of epigenetic regulation in metabolic diseases.
A recent study found that approximately one-third of women taking oral bisphosphonates continue to be at elevated risk for bone fracture. Despite the medication being effective in reducing fracture risk, various factors such as other medical conditions and fall-related problems contribute to this increased risk.
A Kaiser Permanente study found that girls whose mothers were overweight before pregnancy and had gestational diabetes are more likely to experience earlier pubic hair development. The study also suggests that metabolic programming may be affected in the daughters, manifesting in early onset of puberty.
Research reveals snoRNAs control ribosome modification and regulate alternative splicing, leading to wrong protein variants. This discovery explains the cause of diseases like Prader-Willi syndrome and cancer, and offers a possible therapy for genetic hyperphagia.
A study led by NYU's Steinhardt School of Culture, Education, and Human Development found that same-race friendships increase over time, particularly among white students. Teachers' classroom support and differential treatment also play a role in shaping student friendships.
Researchers developed a new technique for fast photonic sensing of freely flowing particles using an opto-mechano-fluidic resonator. The sensor measures compressibility and viscoelasticity of cells and bioparticles, which correlates with diseases like cancers and anemia.
The study reveals that the petunia has a complicated genetic history, having undergone one whole genome triplication shared with all the Solanaceae family. The released parental petunia genomes will be a valuable resource for scientists studying symbiosis, self-fertilization and circadian rhythms.
People driving over an hour a day are 2.3kg heavier and 1.5cm wider around the waist compared to those who drive less frequently. Men are more likely to experience weight gain due to prolonged car travel, according to research by Australian Catholic University.
The Ocean Observatories Initiative is providing real-time access to scientific data and visualizations for public engagement. The platform tracks physical, chemical, and biological properties of the oceans, supporting research and educational activities.
A study published in Scientific Reports found that almost all teenagers engage in risky listening habits, leading to persistent tinnitus and heightened sensitivity to loud sounds. The researchers warn of a major public health challenge as the prevalence of hearing damage is expected to increase.
Researchers developed an algorithm that can stitch together astronomical measurements from around the globe, producing the first images of black holes. The algorithm uses a technique called interferometry and preserves continuity in the image by using a mathematical model inspired by rubber sheets and plastic wrap.
Researchers from Emory University School of Medicine have discovered that chymase inhibitors could extend cell survival after a heart attack. The study found that suppressing chymase activity can prevent late death of heart muscle cells, which occurs several days after blood flow is restored.
Researchers developed CIBs using PB and PBAs as electrode materials, achieving reversible capacities of 40-50 mAh/g. The excellent cyclability is attributed to the durable structure and charge balance during insertion and extraction of calcium ions.
A recent study by the University of Exeter found that roads present a real and growing danger to protected bat populations, disrupting their ability to reach feeding and roosting areas. The research identified over 1,000 bat fatalities caused by collisions with cars.
Researchers from Griffith University's Research Centre for Human Evolution refuted a landmark study suggesting Mungo Man was an extinct lineage of modern humans. The team recovered the genomic sequence of an early inhabitant of Lake Mungo, supporting the argument that Aboriginal Australians were the first inhabitants of Australia.
Researchers have developed an inexpensive and flexible micro-Raman system for non-destructive analysis of biological samples, offering a fraction of the cost and capability of commercial tools. This system allows for label-free detection of variations in biomolecular composition and correlates it with corresponding biological changes.
A WSU biologist has spent 20 years studying the movement of nutrients through plants, confirming an 86-year-old hypothesis about phloem transport. His research could lead to new strategies for fighting plant diseases and improving crop efficiency.
Scientists at USC developed GFE3 protein to modulate brain connections, potentially treating conditions like schizophrenia and cocaine addiction. The protein degrades inhibitory synapses in specific cells, increasing electrical activity.
A study found that nearly two-thirds of younger cancer patients with metastatic disease received hospitalization, emergency room visits, or chemotherapy in their last 30 days. Researchers call for earlier discussions on palliative care to improve quality of life.
Research suggests that galaxies actively launch large amounts of oxygen, carbon, and iron atoms up to a million light years away from their surroundings, leaving them with depleted reserves. This process, driven by violent supernovae and supermassive black holes, can take over 10 billion years.
Scientists at Queen Mary University of London developed a new lighting material using silver, which can emit light with high efficiency and is cheap to produce.
Non-African humans inherited marginally lower fitness due to Neanderthal inheritance, with estimated 40% reduction in reproductively fit individuals. The study suggests that these harmful gene variants continue to reduce the fitness of some populations today.
Researchers found that diverse soil animal communities lead to better decomposition of leaves, regardless of region or management practices. A study of 80 forests in Germany and Sumatra revealed that high species richness and biomass explain spatial turnover in ecosystem functioning.
Researchers developed a new method to measure healthcare value transparently, combining quality and cost measures. They found that hospitals' ability to deliver high-quality, low-cost care varied across procedures, with those providing the highest-value care having more beds and beds than those providing the lowest-value care.
A University of Georgia study finds that people's definitions of moderation vary based on their perception of food, leading to inconsistent behavior. The research suggests that the concept of moderation can be misleading for weight management and obesity prevention.
Research finds that hearing problems impact older people's ability to communicate, move about, and participate in hobbies. Studies show that those with hearing issues have a limited life space and lower quality of life compared to those with good hearing.
The Genomic Data Commons (GDC) brings together genomic datasets and analyzes the data using a common set of methods, democratizing the analysis of large cancer genomic datasets. This platform enables researchers to access and share high-quality data, tools, and support to accelerate studies of cancer biology and personalized treatments.
Oxford University researchers found that infants' cuteness appeals to all senses, triggering caregiving behaviors vital for infant survival. This study reveals the complex choreography of slow, deliberate prosocial behaviors eliciting fundamental brain pleasure systems.
A new study examines the role of diet in promoting cooperation or conflict between gut microbes and human cells. The research proposes a framework for understanding the subtle interplay of diet and health, with potential implications for the management of inflammatory and metabolic disease.
Researchers have identified a protein called TST that helps detoxify waste products in fat cells, leading to improved insulin sensitivity and reduced weight gain in obese mice. The study's findings suggest a potential new approach to treating type 2 diabetes associated with obesity.
Researchers discovered a specific protein in spider venom that stimulates pain-sensing nerves, underlying abdominal pain in irritable bowel syndrome patients. Developing molecules to block this protein could lead to novel treatments for the condition.
Researchers discovered mutations in TMEM230, a new gene linked to Parkinson's disease, in patients from North America and Asia. The gene produces a protein involved in dopamine packaging in neurons, which is crucial for movement disorder diagnosis.
The iSimangaliso Wetland Park is home to a rich biodiversity of water beetles, with 68 species collected from temporary freshwater ponds. These tiny ecosystems are crucial for maintaining wetland health and can serve as indicators of pollution levels.
Late-term infants born at 41 weeks showed improved cognitive performance, including higher test scores and a lower risk of poor cognitive outcomes. However, they also had a higher rate of physical disabilities compared to full-term infants.
A new study by NYU Langone Health finds that music stars' endorsement of food and beverage products are mostly unhealthy, contributing to the rising rate of childhood obesity. The researchers analyzed over 163 identified pop stars' endorsements, finding 81% of their endorsed food products were nutrient-poor.
A study led by Mainz paleogeneticists reveals that early European farmers originated from modern-day Greece and western Turkey, bringing agriculture and domestic animals to the continent. The research challenges previous theories on farming's spread in Europe.
A new study found that intensive glucose treatment can nearly double the risk of severe hypoglycemia in older patients and those with serious chronic conditions. Patients taking multiple medications to lower HbA1C levels were at higher risk of experiencing severe low blood sugar episodes.
A large, randomized international trial has shown that immunotherapy, specifically nivolumab, significantly improves overall survival and quality of life in patients with rapidly progressing head and neck carcinoma. The treatment also demonstrated a lower rate of serious adverse events compared to standard chemotherapy.
A new University of British Columbia study finds that ships flagged for illegal fishing can obtain insurance; researchers propose using vessel list checks to block such vessels from securing coverage. This approach is cheaper and more effective than traditional methods to combat illegal fishing.
A large-scale observational study found significant variations in treatment pathways for patients with type 2 diabetes, hypertension, and depression worldwide. The study analyzed 250 million patient records from four countries and identified unique treatment patterns for each condition.
Stampede 2 is a new large-scale supercomputing system funded by the NSF, providing high-performance computing capabilities for thousands of researchers across the US. The system will employ cutting-edge processor and memory technology, delivering peak performance of up to 18 Petaflops.
A Phase I/II clinical trial found that nivolumab reduced tumor burden in 24.4 percent of patients with metastatic bladder cancer, regardless of PD-L1 marker presence. The treatment was well-tolerated and showed a median survival of at least one year for 45.6% of patients.
A Phase 3 clinical trial found that patients with high-risk neuroblastoma who received two autologous stem-cell transplants had higher event-free and overall survival rates compared to those who underwent a single transplant. The study also showed improved outcomes when immunotherapy was added to the treatment regimen.