A team of researchers has solved a rare, debilitating disease by identifying a genetic mutation as its cause. The disease, Pyrin Associated Autoinflammation with Neutrphilic Dermatosis (PAAND), affects half of the children of patients who have the condition.
Researchers at OIST Graduate University have made a groundbreaking discovery about the behavior of protons inside ice. They found that protons exhibit locally ordered yet globally disordered patterns, which are rare in nature and occur only in ice.
Scientists discovered that microorganisms recognize multiple codons for the rare amino acid selenocysteine, expanding our understanding of the genetic vocabulary. The findings also highlight the context-dependency of the genetic code and its potential plasticity.
A study of over 6,000 mothers and newborns found that maternal smoking during pregnancy chemically modifies a fetus' DNA, mirroring patterns seen in adult smokers. The research identified new development-related genes affected by smoking, suggesting a potential explanation for the link between smoking and health complications in children.
Researchers found a common variant in a non-coding RNA that may contribute to intestinal inflammation in people with celiac disease. The study suggests factors outside of protein-coding genes play a role in the development of celiac disease.
Researchers have successfully demonstrated a strong non-contact heat transfer channel using light, achieving near-field radiative heat transfer between parallel objects at nanoscale distances. The team's approach has the potential to revolutionize energy conversion applications by converting wasted heat from combustion engines back to ...
Scientists can now accurately estimate rainfall amounts by understanding the size distribution of raindrops and snowflakes globally. The new data provides insight into storm growth and behavior, helping predict complex interactions that impact weather patterns.
Coral reefs in the South China Sea are facing severe damage due to dredging and land reclamation. The study reveals that seven atolls have lost ~11.6 km2 of reef area while gaining ~10.7 km2 of land between 2014 and 2015. The researchers call for international cooperation to conserve this critical ecosystem.
Research published in Diabetologia found that people with type 1 diabetes have a three-times increased risk of developing epilepsy later in life. Younger age and severe hypoglycemia are also identified as critical risk factors for brain abnormalities and the development of epilepsy.
The new federal legislation aims to reduce rehospitalization rates by penalizing both hospitals and skilled nursing facilities (SNFs) for rehospitalizations within 30 days. However, clinicians warn of potential problems with the mandate, including inadequate communication between healthcare providers, SNF staff, and patients/caregivers.
Researchers discover a new way to view complex groups of atoms in motion using coherent X-rays, revealing voids and nanocolumns that form during thin film production. This technique improves the quality of commercial applications such as solar panels and drug delivery systems.
A Kansas State University engineer has developed a paperlike battery electrode made from glass-ceramic that improves the performance of tools for space exploration and unmanned aerial vehicles. The electrode has high cycling efficiency and can function at low temperatures, making it suitable for long-duration missions.
Researchers study coastal uplift and erosion in Northern California, discovering rivers cut down hillslopes, triggering landslides that balance uplift. Landslides also deliver resistant rocks to rivers, delaying erosion, with implications for landscape evolution and hazards like landslides.
A new UCLA psychology study suggests that the brain combines sound and vision using different mechanisms, which can influence how well people perform tasks. Researchers found that people's vision frequently influences their hearing when trying to identify specific locations of sounds and flashes of light.
A study published in PAIN found that sleep problems are a predictor of chronic pain and worsening pain severity over time in emerging adults. Sleep problems were more likely to be associated with increased chronic pain, especially in women.
A deep-brain structure called the habenula contains two neural circuits that influence whether a fight will be won or lost in zebrafish. The circuits regulate surrender or continuing aggression based on activity levels in different sub-regions, suggesting a dynamic mechanism for determining fight outcomes.
Researchers at Saarland University are developing intelligent roller conveyor systems that can adapt to changing conditions and detect faults, improving production efficiency. The system uses advanced sensor technology to analyze motor data and adjust its performance in real-time.
The new Strategy for Patient-Oriented Research (SPOR) Network in Diabetes and Related Complications aims to transform health outcomes for individuals with diabetes. The network will focus on improving care and reducing costs for vulnerable groups, including Indigenous peoples, immigrants, women, and lower socio-economic groups.
Researchers have created promising new cold-adapted vaccine strains that can grow at lower temperatures, making them ideal for mass production and distribution. These strains are highly unlikely to cause poliomyelitis in humans and can induce a potent immune response when inactivated.
Renowned researcher D. Yogi Goswami has been awarded the 2016 Böer Solar Energy Medal of Merit for his significant pioneering contributions to solar energy. His work focuses on reducing costs and developing efficient, effective storage methods for solar energy.
University of South Florida researchers discovered a determining factor in red tide occurrences: coastal ocean circulation on the West Florida Continental Shelf. The Gulf of Mexico Loop Current's position determines the likelihood and severity of red tides.
A Scripps Research Institute team has received a $3.4 million grant to develop new therapeutics for addiction and mood disorders. The project focuses on the kappa opioid receptor, which helps regulate dopamine release, aiming to create potent new compounds with minimal side effects.
Astronomers used Hubble to study the Milky Way's nuclear star cluster, discovering a rich tapestry of over half a million stars. The cluster surrounds the galaxy's central supermassive black hole and offers insights into its formation.
A landmark report has called for radical reform of the Medical Council of India to address corruption, lack of uniform standards, and quality issues in healthcare. The report highlights the need for a rigorous transparent system for accrediting medical colleges and creating a robust regulatory framework.
A new study reveals that different mosquito species can affect the evolution of viruses like West Nile. The southern house mosquito appears to be a key driver of West Nile divergence and is more likely to transmit virus variants with greater fitness in avian hosts.
Researchers at MIT have created a programming language that allows users to design complex DNA-encoded circuits in living cells, giving new functions to bacteria and yeast. The language uses Verilog-like syntax and allows users to write programs for specific environmental conditions, such as detecting oxygen or glucose levels.
A study found that agricultural expansion in the Cerrado biome reduces water recycling, affecting rainfall patterns. Double cropping can help mitigate this effect by increasing evapotranspiration rates.
A study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that remote eye gaze tracking can differentiate children with autism spectrum disorder from those without ASD. The researchers developed an Autism Risk Index based on eye gaze patterns, which correctly identified 4 out of 5 cases of ASD.
A new study by Wuhan University of Technology reveals the most efficient ways to conserve energy in homes, including opening windows during heating and using window shades in warm temperatures. The researchers recommend adjusting thermostat settings, adding solar panels, and turning off lights to reduce energy consumption.
Researchers at KU Leuven found that the human brain completes missing parts of objects using visual cues, leading to the 'shrunken finger illusion'. This counterintuitive phenomenon suggests our brains rely on visual system, not imagination, to fill in gaps. The study's findings provide new insights into perception and cognition.
Researchers found a short overnight fast was associated with a 36% higher risk of breast cancer recurrence and 21% higher probability of death. Prolonging overnight fasting intervals may be a simple strategy for reducing breast cancer risk, according to the study.
Global research collaborations study harlequin ladybird's invasion history and ecology, highlighting its ability to thrive in various habitats. Citizen science projects provide valuable information on the spread of invasive alien species, inspiring new approaches to surveying and monitoring.
A new study from San Diego State University found that awareness days, such as the Great American Smokeout, can have a significant impact on smoking cessation. The team analyzed data from news reports, tweets, and quitline calls, and discovered a 61% increase in news coverage and a 25% increase in Google searches related to quitting sm...
Researchers developed a compact system that can synthesize various pharmaceuticals in short periods, reducing batch production and addressing drug shortages. The system produces high-quality drugs continuously over several hours or days, with the potential to facilitate on-the-spot production of pills through new approaches.
A study by Durham University found that climate change is having a similar impact on common bird populations worldwide. Species favored by changing climates outperformed those disadvantaged by warming trends over a 30-year period from 1980 to 2010.
Researchers at UC Riverside found a new species of tumbleweed with a dramatically expanded geographic range in just a decade. The species, Salsola ryanii, is an allopolyploid formed from hybridization between two invasive species.
A recent study by University of Edinburgh researchers has identified two genetic variants that can cut a person's lifespan by up to three years. The variants, which are relatively common in the population, have been linked to an increased risk of lung cancer and severe respiratory problems as well as Alzheimer
A longitudinal study will continue research on language, literacy, cognitive growth, and academic achievement in 137 children from Spanish-speaking homes. The study aims to identify factors that mitigate risks for poor oral language and literacy outcomes.
Researchers found that mimicking simple actions can aid recovery, with human trainers outperforming computer-based methods. The study suggests a potential tool for rehabilitation, providing insight into the ongoing ability of Alzheimer's patients to imitate movements.
Cyanobacteria use internal protein 'machines' to efficiently convert carbon dioxide into sugar during photosynthesis. Researchers developed a method to analyze bacterial cells and found that carboxysomes can adjust their positioning in response to environmental changes.
A novel vaccine strategy has been developed to provide both short-term and long-term protection against the Chikungunya virus. The strategy combines a non-viral, vector-based monoclonal antibody delivery method with a DNA-based vaccine approach.
Researchers encase Arctic plants in ice to study climate change's effects on growth patterns. To their surprise, the frozen plants exhibited increased growth in remaining undamaged shoots.
PharmaMar's Aplidin (plitidepsin) demonstrates a statistically significant reduction in multiple myeloma progression or death, meeting primary endpoint. The study enrolled 255 patients across 19 countries and showed promising results.
Researchers found that female mice exercising during pregnancy had offspring more physically active as adults, suggesting movement influences fetal brain development and lifelong activity. The study supports an environmental role in fetal development and may offer a strategy to counter physical inactivity and obesity.
The researchers genetically modified cyanobacteria to produce enzymes for basic and fine chemicals, utilizing photosynthesis to supply energy. This approach shows promising potential for industrial applications by reducing unwanted by-products and increasing selectivity.
Researchers have found a link between lead contamination in Flint's soil and elevated blood levels in local children, particularly in low-income areas. The study suggests that soil lead is an additional factor contributing to the city's ongoing water crisis.
A national group of sleep and brain injury specialists recommends specific steps to test and develop sleep-related treatments for improved concussion outcomes. The recommendations include data repositories, serial assessment, research targeting treatments, and increased access to sleep treatment services.
A new approach to sequence and assemble primate genomes has been developed using longer sequence reads. This technology has enabled the discovery of missing genes and genetic variation in Western lowland gorillas, providing new biological insights into a living species closely related to humans.
A new study found that women who received seasonal trivalent influenza vaccine during pregnancy were 51 percent less likely to experience a stillbirth than unvaccinated mothers. The study's results support the safety of influenza vaccination during pregnancy and suggest that it protects against stillbirth.
Researchers found chemicals in commonly used fungicides alter gene expression in mouse brain cells similar to those in people with autism and Alzheimer's disease. The study suggests these chemicals may impact brain function, including synaptic transmission and inflammation.
A study by Case Western Reserve University found a dose-response relationship between substance use severity and low-regard for others in adolescents. Adolescents with severe addiction were more likely to engage in riskier behaviors, such as unprotected sex and driving under the influence.
Researchers discovered a white dwarf star with an atmosphere dominated by oxygen, a finding that could rewrite the textbook wisdom of single stellar evolution. The discovery provides critical evidence for some types of supernovae and may be linked to interactions with a nearby companion or massive carbon pulses.
The study reveals that PAR-1 and PAR-2 activation by thrombin and specific peptides differentially regulates eNOS phosphorylation, leading to increased or decreased NO production. PAR-3 induces eNOS-Thr-495 phosphorylation only, whereas PAR-4 is not expressed in human coronary artery endothelial cells.
Researchers at Drexel University found that a protein called TCF4, associated with schizophrenia and Pitt-Hopkins Syndrome, remains present in cells after neurogenesis and restricts synapse formation. This persistence may contribute to the development of these neurodevelopmental disorders.
A new study uses cloud data to map ecological biomes and predict species habitats. The technique has the potential to improve biodiversity research and inform conservation policies.
Researchers have discovered that fossilized snakeskin can retain evidence of skin color from multiple pigments and structural colors, allowing for the reconstruction of ancient animal colors. The discovery opens up new avenues for research into the evolution and function of color in animals.
A new proposal aims to improve cancer care for Indigenous Canadians by using visual arts and participatory dialogue with stakeholders. The project will involve healthcare professionals, administrators, and community leaders from Ontario's First Nation, Inuit, and Métis communities.
Researchers found no significant difference in pain control or bleeding risk between ibuprofen and other treatments. The study suggests that ibuprofen can provide safe and effective pain control for selected plastic surgery procedures without increasing bleeding risk.
A study found that short nightly fasts of less than 13 hours increased breast cancer recurrence risk, while longer fasts were associated with lower HbA1c levels and longer sleep duration. Prolonging nightly fasting may be a simple strategy to reduce chronic disease risks.
Research found that 'thrill of the hunt' and being part of a secret society are prime motivational factors behind purchases. Consumers also experience mixed emotional outcomes, including shame and positive hedonistic feelings.
Astronomers have captured the most detailed image yet of a protoplanetary disc around the young star TW Hydrae, revealing concentric dusty bright rings and dark gaps. The new ALMA images show intriguing features that may indicate a planet with an Earth-like orbit is forming in the disc.
SIAM has announced its 2016 Class of Fellows, a group of 30 distinguished researchers recognized for their outstanding contributions to applied mathematics and computational science. The recipients were chosen for their exceptional research and service to the community.
Researchers at Lund University developed a new method to predict type 2 diabetes risk by detecting epigenetic changes in specific genes through a simple blood test. The study found that higher DNA methylation levels were associated with increased insulin secretion and lower disease risk.
Researchers discover circular RNAs involved in tumor growth and progression, suggesting a new path to cancer treatments. The study provides insights into the role of non-coding RNA in human biology and disease.
A study found that half of patients visiting their GP with dental problems were prescribed unnecessary antibiotics, despite these not providing a definitive treatment. This has raised concerns about the impact on long-term dental health and potential contributions to antibiotic resistance.
Researchers identified a class of drugs called histone deacetylase (HDAC) inhibitors that stimulate T cell movement into tumors and enhance their activity. HDAC inhibitor romidepsin combined with PD-1-targeting antibody leads to lung tumor regression.
A new genetic urine test has been developed to predict high-grade prostate cancer, identifying 92 percent of men with elevated PSA levels who had high-grade cancers. The test could spare hundreds of thousands of men from unnecessary biopsies and reduce the risks associated with the procedure.
Astronomers have captured unprecedented details of the TW Hydrae disk, which may host a super-Earth or an infant version of our home planet. The images show concentric dusty bright rings and dark gaps, including a tantalizing gap at Earth's distance from the star.
A new study reveals that minority groups, particularly blacks and Hispanics, experienced significant declines in homicide victimization rates from 1990-2010. The drops were more pronounced for these groups than for whites, with black-white and Hispanic-black gaps narrowing by 40% and 55%, respectively.
Researchers apply global sensitivity analysis to pinpoint key HIV model parameters affecting treatment plans. By fixing non-influential inputs and minimizing parameter dimensions, they better understand HIV dynamics and develop optimal treatment strategies.
Researchers at Rockefeller University have identified a set of neurons in the fly brain that are activated only when flies eat sweet solutions, especially when hungry. These neurons connect to taste neurons in the pharynx, allowing flies to directly taste and monitor food while swallowing it.
A recent study discovered that microRNA miR-181a suppresses tumor cell proliferation and survival in highly aggressive large B-cell lymphomas by reducing NFkappaB signaling. This finding provides hope for developing novel therapies targeting this pathway.
Researchers develop RolyPOLY, a 20-pound flexible shelter made from robotic winding of carbon fibers. The structure features a modular steel frame assembly and disassembly process for installation and removal.
Researchers have developed a new method to identify protospacer-adjacent motifs (PAMs) for CRISPR-Cas systems, which are crucial for unlocking the system's functionality. The tools allow for rapid identification of PAM sequences across various CRISPR-Cas systems, revealing that some systems have multiple PAMs of varying strength.
Researchers found that wind carved massive mounds of more than a mile high on Mars over billions of years. The study linked the formation of these mounds to climate change on Mars, with sedimentary rocks forming at the base and wind-deposited sediments creating the mound's shape.
Scientists at EMBL have increased the efficiency of gene therapy tool Sleeping Beauty, which is being trialed for therapies targeting B-cell leukaemias and lymphomas. The enhancement results in a 30% increase in efficiency and aims to improve patient outcomes.
A study published in Plastic and Reconstructive Surgery found that plastic surgeons were involved in 40% of cases, including most limb injuries caused by IEDs. The researchers conclude that a team of plastic, orthopedic, and general surgeons can manage almost all modern combat trauma injuries.
A global data management advisory platform, Roadmap, combines the functionality of DMPTool and DMPonline to support open science initiatives. The platform aims to provide a framework for engaging with disciplinary communities, enhancing data sharing, reuse, and discoverability.
Bernard Rollin, a renowned bioethics expert and philosopher at Colorado State University, has been honored with the Lifetime Achievement Award for Excellence in Research Ethics. The award recognizes his seminal work in advancing research ethics, particularly in animal care and use.
Researchers from the University of Zurich found that the diversity of megalodon's prey decreased, leading to its extinction. The team analyzed 200 records and reconstructed the species' range over time, concluding that competition with new predators was a key factor in its demise.
Researchers used cryo-electron microscopy to analyze the Zika virus strain isolated from an infected patient in French Polynesia. The analysis revealed that Zika's structure is similar to other flaviviruses, but with a slight difference in a region important for binding to antibodies and host receptors.
Research highlights the importance of involving young cancer survivors in health behavior interventions and leveraging e-health technologies to support behavior change. The study identifies successful characteristics shared by effective interventions, emphasizing the need for tailored approaches to this population.
A new handheld 3D printing device has been developed to create bespoke scaffolds for cartilage repair, with cell survival rates in excess of 97%. The BioPen allows surgeons to sculpt customised implants during surgery, addressing the challenge of precise geometry.
A study found that only a small percentage of e-cigarette searches are related to quitting smoking, while most pertain to shopping or vaping health. The research used Google search trends from 2009 to 2014 and revealed a significant jump in popularity of 'vape' and 'vaping' terms.
A study by researchers at UC Davis MIND Institute found that a cancer gene is nearly twice as likely to be defective in children with autism spectrum disorder and their fathers. The correlation is particularly high among children with more severe ASD, suggesting a link between DNA repair capacity and genomic instability.
A new genus of treehoppers has been discovered in Texas and northern Mexico, with one species named Selenacentrus wallacei. The researchers found the species among mislabeled specimens from various collections, highlighting the importance of accurate taxonomy.
Researchers have improved upon previous assemblies of the gorilla genome using long-read sequencing technology and algorithms, reducing sequence gaps by 96% and closing 94% of previously identified gaps. The new assembly provides a better understanding of genetic variation between humans and non-human primates.
The world is experiencing a shift in global body mass index (BMI) trends, with more people becoming obese than underweight. By 2025, around a fifth of adults worldwide are projected to be obese, with over 6% of men and 9% of women expected to be severely obese.
High-temperature superconductors exhibit two coexisting states, contradicting the competition-based models previously assumed. The study reveals electronic densities are a combination of separate effects, proposing a new model for understanding these materials.
Researchers at Gladstone Institutes found that increasing levels of protein tau may reverse cognitive deficits caused by Alzheimer's disease. They discovered that tau disrupts memory in models of Alzheimer's disease by depleting protein KIBRA, which is critical for memory formation.
Researchers developed steric trapping method to analyze membrane proteins' folding, showing promise for treating diseases at early stages. The study's findings could lead to medicinal advances in understanding protein structure and function.
A new study found that prostate-specific antigen screening publications led to a decrease in biopsy rates by one-third, while also increasing the relative risk of post-biopsy complications. The researchers identified factors that put patients at higher risk, such as age and prior cancer diagnosis.
African-Americans face significant obstacles to entrepreneurship due to centuries-old racial disadvantages, including limited access to resources and financial services. The majority of black-owned businesses are smaller, have fewer employees, and generate less revenue compared to their white counterparts.
Researchers at Washington University in St. Louis discovered that cancer cells can synthesize lipids from non-glucose sources, contradicting the long-held glucose hypothesis. This finding raises questions about diagnostic methods and treatment strategies for cancer.
Researchers have determined the near-atomic level map of Zika virus, showing a notable difference in one key surface protein compared to other flaviviruses like dengue. This structure may provide clues for understanding how Zika enters human cells and suggest ways to combat the virus with drugs or vaccines.
Researchers from Brigham and Women's Hospital found that dysfunctional mitochondria may not be the primary cause of neurological symptoms in patients with mitochondrial diseases. Instead, brain developmental defects during embryonic development may play a role.
Researchers successfully replicated a range of fault slip modes found during earthquakes, quiet periods and slow earthquakes. They used ground quartz and a machine to apply pressure and alter stresses, revealing the forces behind slow earthquake mechanisms.
UK wine producers face challenges due to climate variability and extreme weather events, which can impact productivity year-to-year. The study found that June rainfall is the most powerful weather indicator in explaining yield variability.
A new study from the University of Texas at Dallas found that firms in corrupt states have lower value and lower informational transparency. Firms on the more corrupt side of a state border also have lower firm value compared to neighboring counties.
New materials and technologies enable innovative applications for contact lenses, including slowing nearsightedness progression, drug delivery and disease monitoring. Researchers propose solutions to clinical challenges in these emerging areas, going beyond traditional vision correction.
Researchers at VIB have discovered that killed tumor cells can be used as a vaccine to stimulate the immune system to prevent cancer cell growth. This finding opens up new perspectives for using necroptosis in immunotherapy and screening for cancer drugs that induce this type of immunogenic cell death.
A new study suggests that companies are more likely to invest in developing socially responsible products when they can tap into the social status boost associated with such choices. Key findings indicate that brands have a greater incentive to innovate in mature categories where consumers are most concerned about environmental impact.
A Kyoto University study found that premature infants, aged 6 and 12 months, showed reduced interest in social stimuli compared to full-term infants. This could be an early indicator of atypical social development, including autism. The research used eye-tracking technology to assess gaze patterns and social interaction skills.
In a rat model of volume-overload-induced heart failure, LOX inhibition partially restored systolic and diastolic function while reducing cardiac fibrosis and interstitial myocardial collagen. LOX over-activation promotes progressive cardiac fibrosis and heart failure progression.
Two drugs, Vismodegib and Sonidegib, target the Hedgehog pathway to treat basal cell carcinoma, a common skin cancer affecting nearly 2.8 million Americans annually. The FDA-approved treatments have shown promise in shrinking tumors and improving response rates.
Viral myocarditis is a leading cause of sudden unexpected death from cardiovascular causes, particularly in men under 40 years old. Chronic myocarditis can lead to dilated cardiomyopathy requiring heart transplantation, with up to 30% of cases resulting from underlying viral infections.
A team of Monell researchers used mice engineered with OMP knocked out to demonstrate that OMP filters 'noisy' signals, allowing accurate odor information to reach the brain. The findings increase understanding of how the olfactory system integrates and transmits data about odors.
Researchers found that metabolically healthy obese individuals tend to be younger and more likely to engage in physical exercise. They were also less likely to smoke or drink heavily. Metabolically unhealthy individuals, on the other hand, had factors such as high cholesterol, age, and smoking status associated with their health.
A team of researchers from Purdue University has determined the structure of the Zika virus, revealing insights critical to developing effective antiviral treatments and vaccines. The study identified unique regions in the virus structure that could explain differences in transmission and disease manifestation.
The new journal issue provides critical input to the World Health Organization's landmark report on aging and health. The research highlights the importance of addressing elder abuse, determinants of health, and medical technology to enable healthier lives for older populations.
A University of Missouri researcher found that certain IT capabilities, including on-site IT professionals and IT infrastructure designed for patient care, boost employee productivity and lead to improved patient care in U.S. hospitals. The study suggests that hospitals with these resources can deliver more effective health information...
Researchers found that aging diminishes the mammalian central nervous system's ability to regenerate axons after a spinal cord injury. As a result, middle-aged adults already have a significantly reduced ability to regenerate compared to young adults.
Researchers at Joslin Diabetes Center have identified the role of natural killer cells in abdominal fat inflammation and insulin resistance. By modulating NK cell activity, they found that inflammation in abdominal fat is suppressed and insulin resistance improves.
A compact, portable pharmaceutical manufacturing system can be reconfigured to produce a variety of drugs on demand. The system is designed to provide an alternative for special situations, such as emergency outbreaks or manufacturing plant shutdowns.
Researchers at Umea University discovered that motor learning relies on the independent control of sensory neurons in muscles. This adjustment allows for selectively informative sensory information to be extracted from spindles during learning.
Researchers at Rice University have determined that 2D boron is metallic and can transmit electrons with no resistance, making it a promising material for superconductivity. The discovery may lead to breakthroughs in small-scale superconducting circuits.
Scientists create miniature retinal organoids that mimic the structure of real retinas, offering new perspectives on retina growth, injury, and repair. The protocol increases yield by up to 4-fold compared to previous methods, enabling researchers to study retinal disease mechanisms and develop therapies for age-related blindness.
Researchers will follow eight crew members over five years to measure changes in muscle strength and function, with a focus on the ankle and knee joints. The goal is to determine when muscle loss levels off and develop countermeasures to limit losses for future Mars missions.
Researchers at Ohio State University Wexner Medical Center have identified altered metabolism of methionine and tryptophan as a driving force behind glioblastoma progression. Restricting dietary intake of these amino acids may slow tumor growth and improve treatment outcomes.
Researchers aim to spare people with type 1 diabetes from lifelong insulin therapy by developing three-dimensional cellular structures of insulin-producing cells. The EU-funded project plans to work with pharmaceutical industry partners to mass-produce the cells for transplantation.
A new study reveals that a targeted immune pathway may be the key to preserving cognitive function in Alzheimer's disease. By blocking this pathway, researchers were able to reduce synapse loss in mouse models of the disease, offering hope for a potential therapeutic target to halt its progression.
A new study from MIT reveals how two populations of neurons in the amygdala form parallel channels that carry information about pleasant or unpleasant events. The findings suggest that to fully understand how the brain processes emotions, neuroscientists will have to delve deeper into more specific populations.
Researchers found Mycoplasma pneumoniae infections in over half of hospitalized children with pneumonia in Beijing, predicting an ongoing epidemic. The study may help clinicians slow the spread of the disease.
Scientists have assembled the gorilla genome using PacBio's long-read SMRT sequencing, achieving a 150-fold improvement over previous assemblies. The new assembly recovers nearly all missing sequence and provides additional euchromatic sequence, enabling researchers to study biological mechanisms and traits.
Researchers found that UPF3A protein plays critical role in RNA regulation and male fertility, potentially leading to new treatments for infertility and various genetic diseases. The study also reveals the importance of NMD pathway in eliminating faulty mRNAs and preventing disease.
Five researchers who designed and executed the National Longitudinal Study of Adolescent Health will receive the Golden Goose Award. The study has provided unanticipated insights into how adolescent health affects wellbeing long into adulthood and laid essential groundwork for research into the nation's obesity epidemic.
Argonne National Laboratory scientists have developed a new method for improving lithium-ion battery performance testing, utilizing a tiny measurement device called a reference electrode. The design enhances the quantity and quality of information extracted from battery cells during cycling, providing crucial insights into battery health.