Researchers at UVA University have successfully used a synthetic gene to manipulate the behavior of mice and zebrafish by applying magnetic fields. The breakthrough could lead to new treatments for neurological diseases such as schizophrenia and Parkinson's disease.
Researchers found that molecules use intermittent search patterns to find targets more than 10 times faster than a simple random walk. This behavior can be optimized for applications like DNA biosensors and industrial production.
Researchers report unusual rugby injuries, including acetabular fractures and hip dislocations in young players. A man also developed distorted vision after inhaling poppers for the first time. Additionally, a patient developed a rare liver abscess after routine dental cleaning.
NASA's RapidScat instrument detected tropical-storm-force winds in a weather system affecting the Pacific Northwestern U.S. and southwestern Canada, bringing rain and snow to the region. Heavy rainfall totals of over 8 inches were estimated in some areas, with potential to alleviate California's long-lasting drought.
A recent study by MIT biologists found that cancer cells use amino acids to build new cell mass, contradicting the long-held assumption that glucose is the primary source. The largest contributors to cell mass were amino acids, making up 20-40% of total mass.
Research by WSU's Joyce Ehrlinger and colleagues found that those with a fixed mindset about intelligence tend to be overconfident, while growth mindset holders are more accurate in their self-assessment. This imbalance can lead to poor decision-making and missed learning opportunities.
A long-term study found a correlation between the use of animal manure and an increase in antibiotic-resistant genes in soil. Phasing out antibiotics led to a rapid decrease in resistant gene abundance, suggesting that stopping antibiotic use can help reduce resistance levels.
A cross-sectional survey found that detailed clinician communication can alleviate patient distress associated with incidental pulmonary nodules. Patients who received accurate information about their nodule size and diagnosis had a more reassuring experience, reducing anxiety and improving overall well-being.
Aurorasaurus uses citizen science observations to improve short-term predictions of aurora displays and study geomagnetic storms. The project tracks auroras worldwide, providing valuable data for scientists.
A study in mice reveals a specific brain region, the ventrolateral part of the ventromedial hypothalamus, is responsible for aggressive motivations that lead to violence. The research suggests targeting this region could lead to better control of aggressive behaviors without sedation.
A novel text analysis technology developed by Ambiverse improves searching large text collections with artificial intelligence, resolving ambiguities automatically. The technology assists authors in researching and writing texts by providing background information and suggesting links to relevant web sites.
Researchers at U of T Engineering have developed a new way of growing realistic human tissues outside the body, called AngioChip. The technology uses a three-dimensional structure complete with internal blood vessels and can be used to test drugs on lab-grown human tissues, providing a realistic model at a fraction of the cost.
Researchers have pinpointed the effects of Huntington's disease on a specific brain area responsible for complex movements, such as talking or playing music. The study suggests that reintroducing normal patterns of activity in this area may be sufficient to restore normal behavior, offering potential therapeutic targets.
A new study found that premature infants' gut bacteria are vulnerable to antibiotic resistance, with almost 800 genes identified, including those associated with carbapenem-resistant Enterobacteriaceae. The study suggests that routine antibiotic use in preterm infants may not be effective and could lead to increased infection risk.
A new study suggests that pyroclastic flows from a 18.8 million-year-old supervolcano eruption traveled in dense, slow-moving currents, covering over 100 miles. The research supports the idea that these flows are fluid-like, with pressurized gas between ash particles, and has implications for disaster preparedness efforts.
Scientists at Scripps Research Institute have identified a novel drug candidate that targets serine biosynthesis in cancer cells, inhibiting their growth. The new compound, CBR-5884, specifically targets the enzyme PHGDH, which is responsible for serine production, and shows promise in treating breast cancer, lung cancer, and melanoma.
A new class of 'BH3-mimetic' drugs has shown promise in treating Legionella-infected cells by targeting the BCL-XL protein. This research could lead to new treatments for various bacterial infections, even those resistant to antibiotics.
A novel in-situ plasma processing technique has been successfully applied to superconducting cavities at the Spallation Neutron Source (SNS), significantly improving neutron production and accelerating beam energy. The technique uses hot plasma to clean hydrocarbon contamination from surfaces, reducing maintenance time and costs.
Researchers from KU Leuven found that frequent antibiotic use leads to the development of persister cells, which are dormant and tolerant to antibiotics. This phenomenon can lead to the recurrence of infections despite successful treatment.
Rutgers University has developed a promising antimalarial compound, SJ733, which could help fight the long-dreaded disease. The compound works by blocking a malaria parasite protein, causing water to rush in and 'blowing up' the parasite inside human blood cells.
Researchers are developing a network of advanced sensors to detect particulate matter and pollen in metropolitan areas, providing real-time data for improved public health. The project aims to create an open-access platform for mapping pollution levels and supporting remediation efforts.
Researchers found that a cell aging program increases insulin secretion in human and mouse pancreatic beta cells, improving their function. This discovery suggests that cellular aging can bring unexpected benefits to the production of insulin, potentially leading to new insights and treatments for diabetes.
A Boston College study reveals that Catholic schools are inadequately prepared to educate the growing Hispanic Catholic population in the US. The study highlights disparities in recruitment, training, and cultural sensitivity among school leaders and teachers, which stifle school vitality and the Church's engagement with this young gen...
A new blood test can detect early warning signs of skin cancer relapse in advanced melanoma patients by tracking levels of circulating tumour DNA. The test identifies new mutations in genes like NRAS and PI3K, which may cause the relapse.
Researchers investigated wind patterns and affecting weather systems around the shipwreck location. The study revealed strong winds of at least 31 m s-1, and a bow echo embedded in a squall line contributed to the disaster.
A Korean research team has developed metabolically engineered Escherichia coli strains to synthesize non-natural, biomedically important polymers including poly(lactate-co-glycolate) (PLGA). The team successfully produced PLGA and various novel copolymers through microbial fermentation directly from carbohydrates.
Researchers from Cardiff University have demonstrated the first practical laser grown directly on a silicon substrate, paving the way for ultra-fast communication between computer chips. The breakthrough has the potential to transform various sectors, including communications, healthcare and energy generation.
Climate change poses a significant threat to African food production, with up to 30% of maize and banana-growing areas becoming unviable by the end of the century. Transformation could involve changing crop types, improving irrigation systems, or abandoning agriculture altogether to ensure food security.
A recent study by University of Massachusetts Amherst researchers suggests that the destruction of oyster reefs in New York Harbor led to a significant increase in storm-induced overwash deposition. The authors found that before European settlement, oyster beds absorbed wave energy, providing coastal protection.
A recent study found that epaulette shark embryos can withstand ocean acidification conditions predicted for the year 2100, but may be vulnerable when gills are still developing. This suggests that sharks may be more resilient than previously thought, but their survival depends on maintaining healthy habitats.
The University of Liverpool's National Institute for Health Research has announced a £100,000 funding boost for Zika virus research to tackle the current outbreak in South America. The funding will support eight projects focusing on diagnostics, clinical studies, and understanding the disease mechanism.
A recent study found that women who underwent a double mastectomy showed little improvement in quality of life compared to those who had a single mastectomy. However, breast reconstruction was found to have a significant positive impact on psychosocial well-being and breast satisfaction.
Five Clemson University researchers have won prestigious awards for their groundbreaking work in developing new medicines, making robots fly, saving buildings from demolition, and creating more efficient fertilizers. The awards bring $2.2 million in new research funding to the College of Engineering and Science.
A new study by Brown and Tufts universities found that climate change can reduce agricultural production in the Brazilian state of Mato Grosso by 9-13% with a 1 degree Celsius temperature increase. The research considered crop yield, land area, and double cropping to provide a more comprehensive understanding of climate change's effects.
A study by Drexel University researchers found that sudden insights are more likely to be correct than answers derived from analytical thinking. The experiments used timed puzzles and showed that responses given during insight were often correct, while those from analytical thinking were less accurate.
Researchers found that deleting the huntingtin gene in adult mice does not lead to lethal consequences, offering hope for treatment strategies involving gene silencing. The study suggests that gene suppression or editing strategies may be safe for adults, but further research is needed to understand the long-term effects.
Researchers at Brigham Young University have developed origami-inspired engineering techniques to create ultra-small surgical instruments, allowing for minimally invasive procedures. The technology aims to reduce the size of incisions necessary for surgery, potentially enabling self-healing wounds without sutures.
Researchers found that targeting high prescribers of Schedule II controlled substances with informative letters did not significantly reduce overprescribing, but the study's findings still have important implications for policymakers aiming to curb prescription drug misuse.
Researchers used an experimental game to study how government representatives make decisions in social dilemmas. The results show that selfish representatives who contribute less than their fair share can still be re-elected and lead their countries to reach the target sum, while others contribute more. This study highlights the comple...
New research reveals that global warming will increase rainfall in dry regions, but the additional water may not be available due to increased evaporation. This could lead to more frequent and intense flash flooding events in areas without adequate infrastructure.
A molecule has been identified that promotes a sleep-like state in nematode worms, which is similar to the sleep of humans and other mammals. The protein VAV-1 regulates this process and is also involved in maintaining normal amounts of EGFR in the neuron.
Researchers at VCU Massey Cancer Center have developed a combination therapy that targets the MYCN and BCL2 proteins to kill neuroblastoma cells. The therapy, which uses investigational drugs ABT-199 and MLN8237, shows promising results in laboratory experiments and advanced mouse models.
Researchers at the University of Edinburgh found a compound called cathelicidin that directly attacks and stops RSV from binding to cells. Boosting natural production of this compound could protect babies and vulnerable adults from life-threatening illnesses.
Researchers at the University of Southampton have discovered a direct link between fault activity and water entering the Earth's mantle. The study found that the amount of serpentinite formed at the bottom of each fault is directly proportional to the displacement on that fault.
Researchers developed a new technique called TraCeR that determines both the sequence of T-cell receptors in individual cells and each cell's gene expression profile. This allows for the study of how different populations of T cells respond to disease, enabling the exploration of immune responses in various conditions.
Researchers at Pohang University of Science & Technology developed a miniaturized solid oxide fuel cell that can power drones for more than an hour. The fuel cell's high power density and durability make it suitable for portable electronic devices, including smartphones and laptops.
New research reveals that empathy is composed of two forms: cognitive (understanding) and affective (feeling). When partners have accurate knowledge but lack compassionate feelings, they tend to be less supportive. However, when both accuracy and concern are present, responsiveness increases.
Research at Duke University Medical Center found that prostate cancer patients with lymph-only metastasis have the longest overall survival, while those with liver involvement fare worst. The study analyzed outcomes of 8,736 men with metastatic prostate cancer and provides valuable information on prognosis and treatment approaches.
Researchers have discovered that amyloid protein build-up is greater on the left side of the brain, where language processing occurs, in individuals with primary progressive aphasia (PPA). This study provides new insights into the disease process and offers hope for early diagnosis and treatment.
A randomized controlled trial found that electronic consultations improved access to cardiac care, with nearly two-thirds of patients not requiring a face-to-face visit. Additionally, e-consultations were completed on average almost a month sooner than traditional consultations.
Researchers found that neglected neighborhoods with poor street lighting, vacant lots, and fewer parks had higher rates of teen homicides. Modifying these features through low-cost improvements may foster community interaction and reduce youth violence.
Up to three million US employees go to work sick each week, mainly due to lack of paid leave coverage. Employees in low-wage sectors, females, and young adults are more likely to work while ill.
Researchers have developed new tools to understand the complex relationships between ocean-borne compounds and microbes, revealing a vast network of molecular connections that store and transform atmospheric carbon in the world's oceans. The study focuses on dissolved organic matter, or DOM, as a central carbon reservoir.
Children born to mothers with vitamin D deficiency during early pregnancy are at a higher risk of developing multiple sclerosis (MS) in adulthood. The study found a significant association between maternal vitamin D levels and MS risk in offspring.
A University of California, Irvine study found that global warming affects the soil fungi that support plant life in tropical mountain cloud forests. The impact on these ecosystems could be significant, with changes to fungal community composition and increased carbon dioxide emissions.
Researchers at Rice University discovered that cancer cells can consume amino acids directly from exosomes, tiny packets of proteins and nucleic acids, to fuel tumor growth. This finding contradicts the long-held Warburg effect theory, suggesting each type of cancer has a unique metabolic profile.
A research team at the University of Delaware has designed softwood lignin-based polymers with improved thermal and flow properties, making them suitable for applications such as tires, running shoes, and gaskets. The development aims to reduce costs and environmental impact by utilizing waste from the pulp and paper industry.
Researchers have identified a new therapeutic target for multiple myeloma, targeting CDK4 and ARK5 proteins. The compound ON123300 showed potent cytotoxicity against myeloma cells while sparing normal peripheral blood cells.
Researchers have developed a new flexible 'meta-skin' technology that can cloak objects from radar waves using rows of small liquid-metal devices. The meta-skin demonstrates 75% radar suppression in the frequency range of 8 to 10 gigahertz, making it suitable for electromagnetic frequency tuning, shielding and scattering suppression.
Geneticists at UNIGE sequenced DNA of skin tumors to determine genes responsible for cancerogenesis in basal cell carcinoma. New cancer genes MYCN, PTPN14 and LATS1 were identified, which can complicate treatment.