Research findings suggest that gut microbiomes of patients with antiphospholipid syndrome show higher levels of phospholipid-producing bacteria, pointing to microbes as a trigger for the disease. The study identified Slackia bacteria as a promising candidate, which can produce phospholipids including cardiolipin.
New research findings suggest that men and women have different post-surgical outcomes after total hip arthroplasty. Women who had improved functional recovery showed more abductor strength improvement and better gait function during walking. Tailoring rehabilitation to each sex may help patients achieve better outcomes.
A study presented at the American Heart Association's Scientific Sessions found that black and Hispanic children are more likely to receive compressions-only CPR, but conventional CPR leads to better survival rates. Conventional CPR also improves brain function and discharge outcomes in infants.
Studies in the US and Denmark show that older adults are undertrained in CPR, with only 18% reporting current training. Higher education level and household income are linked to increased likelihood of CPR training, but there is a steep drop-off after age 50. The elderly often cite lack of knowledge and fear as barriers to performing CPR.
A new training model improved CPR skills among hospital staff by integrating low-dose-high frequency psychomotor simulation into their daily duties. Quarterly simulations resulted in significant improvements in chest compression fraction and overall clinical outcomes, leading to a 14% increase in effective compressions.
Researchers found that patients treated with rituximab as their first biologic had a lower mortality risk compared to those treated with TNFi. The study included 353 patients with RA-ILD and analyzed five-year mortality rates, with RTX-treated patients showing numerically lower but not statistically significant risks.
Research finds elevated myocardial inflammation in RA patients, with treatment showing potential to improve inflammation levels. Studies use advanced imaging techniques to detect and quantify heart inflammation, suggesting a link between joint and heart inflammation.
Researchers found a significant interaction between TNF-inhibitors and NSAIDs, with patients experiencing a 70% reduction in radiographic progression when used together. The study suggests that combining these therapies may be especially helpful for patients at higher risk of disease progression.
Research shows that many patients with RA, spondyloarthritis, and other inflammatory joint diseases are not receiving adequate CVD-preventive medications, despite being at high risk. Only half of those who start treatment achieve their goals, highlighting a significant need for improvement in CVD prevention.
Researchers identified three gene expression signatures that can help rheumatologists predict which patients are more likely to respond to certain therapies. The findings could lead to higher response rates and reduced likelihood of ineffective treatment, ultimately improving patient care.
A study of 564 patients found that women with long-term axial spondyloarthropathy are at higher risk for extra-articular manifestations, including uveitis, which is significantly more prevalent in women (46.7%) and those in late disease stages. IBD prevalence was also higher in women (16.5%), particularly those with elevated CRP levels.
Research suggests that RA patients who receive combined care from primary-care physicians and rheumatologists are more likely to be screened for hyperlipidemia. This study found that 47% of patients seeing both a PCP and rheumatologist were screened, compared to 42% of those seeing only a PCP.
A study of 9,362 surgeries on 5,544 RA patients found that continuing DMARDs prior to surgery does not increase post-operative infection risk. Researchers recommend considering medication continuation during the perioperative period to maintain better control over RA and reduce complications.
A study found that prior statin use was associated with higher survival rates after out-of-hospital cardiac arrest. Patients with Type 2 diabetes showed the most significant improvement in survival rate. Statins were linked to increased survival to hospital discharge and beyond a year after the event.
The U.S. adult rheumatology workforce is projected to decline by 31% by 2030 due to an aging workforce and insufficient graduate medical education funding. To address this gap, researchers suggest creating financial incentives for medical students and residents to pursue rheumatology training.
A retrospective cohort study found that chronic kidney disease patients who achieve target urate levels show improvement in kidney function. The study suggests that urate-lowering therapy may help stabilize or improve kidney function in patients with significantly elevated serum uric acid and moderate kidney failure.
A study of over 3,900 US children who suffered cardiac arrest outside a hospital found that those receiving bystander CPR had better survival rates and neurological outcomes. Racial disparities in CPR provision were also noted, highlighting the need for education interventions to improve minority community access.
Researchers found that people with RA have double the risk of CV events as those in the general population, rates similar to those with type-2 diabetes. Chronic inflammation in RA contributes independently to cardiovascular risks for these patients.
A multicomponent behavioral intervention delivered by lay health workers significantly reduced anxiety and depression in adults with high levels of psychological distress. The study found improvements across all dimensions, including trauma-related symptoms and functioning.
A Mayo Clinic study found that type 1 interferon beta levels are associated with poor response to tumor necrosis factor inhibitors in rheumatoid arthritis patients. This discovery may lead to more personalized treatment approaches based on individual patient biology.
Researchers found distinct monocyte gene expression signatures in RA patients with different responses to anti-TNF therapy, potentially leading to personalized treatment approaches.
New research from the American College of Rheumatology finds that most people with knee osteoarthritis (OA) meet the minimum physical function level necessary to walk at least 6,000 steps a day. This suggests that many individuals with OA can adopt physically active lifestyles and achieve significant health benefits.
A survey found that older Americans, those with lower education levels and household incomes, are less likely to receive CPR training. This lack of training can lead to a higher risk of sudden cardiac arrest, as bystanders may not know how to intervene in an emergency situation.
Quality of care varies significantly among rheumatology practices, with the largest gaps seen in osteoporosis and gout care, and some practices consistently performing well across measures. The study highlights the need for improvement in preventive care and counseling, and RISE provides a tool for guiding quality-improvement efforts.
New research finds that African-Americans, Asians, and those with a high school education or less experience significant delays in receiving lupus diagnosis and treatment. The study highlights the need for targeted solutions to address these disparities in access to specialty care.
Research finds that tumor necrosis factor inhibitors used to treat juvenile idiopathic arthritis do not increase the risk of malignancy. The study, which analyzed data from over 27,000 children with JIA, concluded that TNFi are not associated with a significantly increased risk of incident malignancy.
Research found no association between allopurinol use and increased risk of chronic kidney disease (CKD) Stage 3 or higher in gout patients with normal kidney function. Allopurinol may be beneficial for preventing renal decline, suggesting its safe use in managing gout symptoms.
Researchers found that statin initiation was associated with a 33% reduction in all-cause mortality among AS and PsA patients. The study suggests that statins' dual benefits of lowering lipids and reducing inflammation may be the reason for this significant benefit.
A new Wnt inhibitor drug has shown significant improvements in knee OA pain, joint function, and even slowed or reversed cartilage loss. The study found that the drug improved outcomes for 76% of patients in the high-dose group compared to 36% on placebo.
A recent study published in JAMA Pediatrics found that receiving cardiopulmonary resuscitation (CPR) from a bystander improved overall and neurologically favorable survival for children with out-of-hospital cardiac arrest. The study analyzed data from over 3,900 cases and showed that conventional CPR provided better outcomes than compr...