The BIONICS trial found that the ridaforolimus-eluting stent was non-inferior to the zotarolimus-eluting stent in terms of target lesion failure rates and had a low rate of stent thrombosis. The study, which enrolled over 1,900 patients, showed similar outcomes for cardiac death, TV-MI, and ID-TLR.
The ILUMIEN III trial found that optical coherence tomography-guided PCI resulted in similar minimal stent area compared to IVUS-guidance, while also showing improved stent expansion and acute procedural success compared to angiography-guidance. Untreated major dissections were more common after IVUS-guided PCI than OCT-guided PCI.
Research by Natalia Karelaia finds that social connectedness enhances the perceived effectiveness of actions, leading to increased social responsibility. Studies show that people who feel a sense of belonging and can make a difference are more likely to engage in environmentally conscious behaviors.
A team of researchers at Tokyo Medical and Dental University has identified a molecule called CD72 that prevents the immune system from mistakenly reacting to a component of the body's own cells. This breakthrough could lead to new treatments for systemic lupus erythematosus (SLE), a disease associated with inflammation of various organs.
Scientists at the John Innes Centre have developed a new MutChromSeq technique that reduces the complexity of searching for specific genes in wheat and barley genomes. This method uses chromosome flow sorting to narrow down the search area, making it faster and cheaper to sequence just one chromosome.
The BIO-RESORT trial found that two thin-strut biodegradable polymer everolimus-eluting and sirolimus-eluting stents were non-inferior to a durable polymer zotarolimus-eluting stent in treating coronary artery disease. Patients with acute coronary syndromes showed excellent one-year clinical outcomes.
A majority of British scientists who mentioned Richard Dawkins during research interviews reject his public engagement approach, feeling he misrepresents science and its norms. The study's findings emphasize the importance of promoting science over personal attacks to effectively communicate scientific knowledge.
A team of researchers discovered that maintaining DNA methylation is closely linked to hybrid vigor in Arabidopsis thaliana, a model plant for studying hybrid plant superiority. The study's findings suggest that epigenetic regulation plays a crucial role in hybrid vigor.
Researchers found that extreme heat during pupal life stages is detrimental to over half of UK species, while precipitation can be detrimental to up to a quarter. However, some life stages may benefit from climatic extremes, with warm summers causing positive population changes in over one-third of the UK species.
A recent study found that hybrid structures composed of DNA and RNA play a crucial role in restoring genetic information after damage. The research also revealed that RNase H enzymes targeting these hybrids are vital for efficient DNA repair. This discovery offers potential for developing new cancer drugs targeting these enzymes.
The study reveals a striking pattern of genome duplication in the African clawed frog, which arose through interspecific hybridizations between 15-20 million years ago. The research has significant implications for understanding human conditions and diseases, as well as applications in regenerative therapy.