A new study suggests that intensive treatment of systolic blood pressure to below 120mmHg can reduce mortality by 27%, with an estimated 107,500 deaths prevented per year. However, this approach also carries a significant risk of serious side effects, including low blood pressure episodes and fainting.
A new study found that patients with anxiety, phobias, and fears show greater improvement from therapy scheduled in the morning when cortisol levels are high. Morning sessions help psychotherapy patients overcome panic and anxiety better due to increased cortisol, facilitating fear extinction.
Researchers created a patented vaccine to combat Fusobacterium necrophorum infection, which affects sheep and cattle with liver abscesses and calf diphtheria.
Researchers have engineered a magnetoelectric multiferroic material that combines electrical and magnetic properties at room temperature. This new material could enable devices with lower energy consumption, addressing the growing concern of electronics being the fastest-growing consumer of energy worldwide.
Researchers at MIPT and several universities create technology to determine spatial structure of receptor proteins, crucial for human health. By using sulfur atoms and Serial Femtosecond Crystallography, scientists solve the problem of radiation damage, enabling precise analysis of protein structures with a resolution of 1.9Å.
The new motor uses a precisely machined hollow iron ball to move in any direction using electronic controls, reducing mechanical failures and maintenance. SIMbot can maintain its balance while moving at speeds of up to 1.9 meters per second, making it capable of navigating through doorways and furniture.
Residents of high-unemployment communities showed elevated post-traumatic stress at 25-28 months after Hurricane Sandy, highlighting the need for ongoing support. Ongoing assistance is crucial for disaster-affected economically vulnerable communities years after the disaster.
A new study found that people with a defective gene variant prefer high-fat foods over sugary ones, contributing to weight gain. Researchers tested participants with lean, obese, and MC4R-defective genes, showing a link between genetic variants and food choice.
Researchers at Oak Ridge National Laboratory have discovered that complex oxide materials can form self-organized circuit elements, which could support new computing architectures. This breakthrough enables the creation of multifunctional chips with tailored inputs and outputs for specific applications.
Researchers studied nerve regeneration in roundworms and discovered a signaling pathway that induces nerves to regenerate. This pathway is also involved in clearing dying cells, suggesting a potential target for improving human recovery from nerve injury.
A HKU undergraduate student applied THMOCALC phase-equilibrium modeling technique to determine pressure-temperature conditions of Eastern Hebei mafic granulites. Her research yielded accurate results, reflecting an origin related to underplating of mantle-derived magmas.
Columbia researchers have identified 41 key genes that may contribute to gum disease, offering a promising approach to developing individualized treatments. The study's findings could lead to new compounds that target specific genetic pathways involved in the disease process.
Researchers at HZDR propose a new mechanism linking planetary tidal effects to the Sun's dynamo, which could drive the 11-year solar cycle. The theory suggests that small forces from Venus, Earth, and Jupiter can initiate oscillations in the alpha effect, leading to polarity reversals.
Researchers at Oak Ridge National Laboratory develop direct-write technology to create nanoscale patterns in metallic ink, allowing for tailored material properties and customized architectures. The technique uses a scanning transmission electron microscope to control the deposition of metal onto a silicon microchip.
Researchers found bumblebees can solve string-pulling task through social learning, with 60% of untrained bees solving it after watching others. The skill continues to spread even after the original string-puller is gone.
Engineering researchers at the University of Texas at Austin have developed a new method for delivering chemotherapy directly and efficiently to individual cells using nanoparticles called 'connectosomes.' This approach has been shown to reduce the dose required to kill cancer cells by up to 10 times, potentially decreasing side effects.
The paper explores various techniques for brain-machine control, including EEGs and near infrared spectroscopy, to facilitate communication and rehabilitation in paralysed patients. Brain-machine assistive interfaces enable patients to communicate or control external devices such as prostheses.
A leading doctor argues that the junior doctors' contract should be discarded and replaced due to a breakdown of trust between government and healthcare staff. The current contract has been criticized for being inefficient and damaging to morale among young doctors.
A new study aims to evaluate treatment strategies for older adults with depression who have not responded to medications. The researchers will compare the effectiveness of switching people to a new medication or augmenting their current medication with a second drug.
Scientists have successfully transferred massive amounts of data from ITER to Japan, paving the way for remote experiments and 'big data' analyses in fusion energy research. The achievement is made possible by a synergetic effect of collaboration between international partners.
A study found that disease-causing gut bacteria, Enteroaggregative E. coli, are prevalent in 14% of children, even in industrialized countries with mild symptoms. The researchers hope to investigate factors contributing to diarrheal disease and explore probiotic agents for maintaining gut balance.
The grant aims to create partnerships in disaster-prone regions to enhance national capacity for children's and families' post-disaster response. It adapts the National Child Traumatic Stress Network model, including a digital application for information sharing after disasters.
Researchers have discovered molecules that prevent free radical production by cells, which are implicated in human diseases and the aging process. The findings offer a precise tool to test the free radical theory of aging and could lead to new therapeutic leads for drugs.
Researchers found that mothers experience a greater 'work' of parenting tasks while fathers enjoy more leisure time with their kids. This imbalance leads to increased stress and fatigue among mothers.
The novel 'Rheo-Raman' microscope allows for interconnected studies of soft materials by correlating their microstructure, composition, and flow behavior. This enables the understanding of how structural make-up dictates macroscopic properties like strength, hardness, or electrical conductivity.
A study from Duke-NUS Medical School found that activity trackers alone or with rewards did not increase physical activity levels. However, those who received cash rewards showed significant increases in activity. The benefits of tracking were short-lived, and participants returned to their previous activity levels after the incentives...
Scientists have discovered how ataluren works to treat genetic disorders by allowing the cell's machinery to 'run' over premature stop signs. The drug inserts amino acids similar to those in non-mutated genes, enabling proteins to function normally.
Researchers found that mice can maintain learning and memory when virtually all ApoE is removed from the brain, as long as it remains present in the liver to filter cholesterol. This study supports the belief that reducing ApoE in the brain could be a viable therapeutic option for treating Alzheimer's.
Women with extremely high breast density are more likely to develop breast cancer, and current mammography technology may miss tumors. Researchers are working to improve breast cancer diagnosis and health outcomes for women through education and better utilization of screening methods.
Researchers at Drexel University have made a breakthrough in the study of how things break, bend and deform. They discovered that layered materials form internal buckles, or ripples, as they deform under stress, dubbed 'ripplocation'. This new paradigm explains non-linear elastic behavior within the constraints of dislocation theory.
Researchers mapped the first active human apoptosome, a wheel-like structure that recruits proteases to dismantle proteins and induce cell death. The study provides insights into how this process is regulated and may lead to treatment options for cancer, AIDS, and neurodegenerative diseases.
A team of researchers has uncovered the detailed structure of a Type IV pilus, revealing how it binds to and disrupts endothelial cell junctions to breach the blood-brain barrier. This discovery could lead to new ways of treating meningococcal infection and potentially even therapies that deliberately open the blood-brain barrier.
Scientists at Scripps Research Institute are exploring the applications of 'click chemistry' for cancer research and polymer development. A new four-year project aims to understand the role of fucosylated sugar molecules in cancer, while another project seeks to create new clicked polymers with improved properties.
The University of Pennsylvania has been awarded a $24 million grant to establish a Science and Technology Center focused on engineering mechanobiology. This research will provide insights into embryonic development, stem-cell differentiation, cancer metastasis, and other clinically relevant topics.
Researchers developed an objective test to diagnose mild traumatic brain injury (mTBI) using the I-Portal goggle, achieving 95% specificity and 89% sensitivity. This technology has the potential to revolutionize concussion diagnosis and treatment in sports, leading to better outcomes for athletes.
A systematic review of 10 international studies suggests that diffusion tensor imaging (DTI) may be an effective diagnostic tool for identifying and predicting the likelihood of post-concussion syndrome (PCS). DTI scans can detect micro abnormalities in the brain not picked up by routine imaging methods, potentially leading to earlier ...
Researchers identify peptide allatostatin A in Drosophila that regulates feeding behavior and promotes sleep, with effects comparable to human galanin receptor. The study provides insights into the complex interactions of hunger, sleep and digestion.
A new measurement tool, developed by York University researchers, measures the spreading of liquid drops on surfaces. The study suggests that an advanced swimsuit could reduce fluid resistance underwater, potentially helping athletes achieve better times.
Researchers created simple microswimmers with a phototaxis system, enabling them to move towards darker areas. By using a laser-generated light field with saw-tooth profiles, the microswimmers can be steered reliably over long distances.
A new study compares Botox to sacral neuromodulation as treatments for urge incontinence, finding that Botox provides more daily relief but may be associated with more adverse events. The study analyzed data from 381 women and found a significant reduction in symptoms with botulinum toxin.
The UK government is investing £17.7 million in four new healthcare technology research programmes to tackle the growing need for treatments of diabetes, dementia, and cancer. The programmes will develop innovative solutions for wound care, neural rehabilitation, cell therapeutics, and immunotherapeutics.
Researchers found significant links between hyperactivity, lower blood phospholipid levels, and a negative correlation with tryptophan metabolites in hyperactive dogs. This study suggests that intestinal health impacts canine behavior and provides new clues for studying behavioral disorders.
Researchers found that vitamin D influences inflammatory signals controlling blood stem cell formation and multiplication. Vitamin D exposure led to an increase in blood stem cells, while deficiency resulted in fewer cells being formed.
Patients with septic shock who experience bradycardia (lower heart rate) have a 21% lower mortality rate compared to those without. A 13% decrease in mortality risk was observed among patients with average lower heart rates below 80 beats per minute.
Researchers discovered that ultra-relativistic electrons are scattered into the atmosphere by electromagnetic ion cyclotron waves, while relativistic particles remain intact. This finding resolves a long-standing debate on electron loss mechanisms in the Van Allen Radiation Belts.
Researchers at Rice University have found a new, wavy two-dimensional material called borophene that could be ideal for creating flexible electronic devices. The material has excellent conductivity and can stretch without losing its electronic properties.
Extending cervical screening intervals for HPV negative women aged 40+ is safe due to low risk of CIN3+, but not recommended for those testing positive for HPV. Tailoring screening to individual risks using HPV test results and age may improve efficiency and optimal prevention.
Researchers at HZB and Marburg developed an expert system that identifies small molecule fragments bound to proteins in raw X-ray diffraction data. The system has been successfully tested on 364 samples, revealing additional candidates for drug development.
A new study from Harvard T.H. Chan School of Public Health found that nearly 25% of low-income adults in three US states switched their health coverage within the previous 12 months, resulting in significant negative effects on healthcare, including frequent gaps in insurance, skipped medications, and low-quality care.
A comprehensive study of Hawaii's mesophotic coral ecosystems has documented vast areas of 100% coral cover and extensive algal communities at depths of 50-90 meters. The findings reveal unique species not found on shallow reefs, with significant implications for conservation.
A new device can rapidly identify harmful bacteria and determine its susceptibility to antibiotics in a matter of minutes. The device uses nano-scale technology to detect bacteria in extremely small fluid samples, offering a potential solution to the growing problem of drug-resistant strains.
A new rare ant species, Lenomyrmex hoelldobleri, has been discovered in the stomach of a Little Devil poison frog in Ecuador. The ant is the seventh known species in its rarely collected Neotropical genus and features a slender elongate mouthpart.
A new study by USC scientists has mapped the electric current induced by transcranial direct current stimulation (tDCS) in the human brain. The research provides solid data to develop science-based treatments for neurological and psychiatric disorders, including depression and chronic pain.
Researchers developed a transparent metal electrode with improved efficiency, using fractal-like nano-features inspired by leaf veins. The new design combines low surface coverage and ultra-low resistance, surpassing conventional indium tin oxide layers.
Scientists have discovered that certain plants resistant to a hormone called abscisic acid (ABA) can grow better than normal neighbors during droughts. ABA-resistant varieties may hold the key to breeding 'stay green' traits in crops, which could help them retain their leaves and continue to produce food and other essential resources.
A study by Carnegie Mellon University researchers analyzed Hillary Clinton's two political memoirs, revealing links to her public perception problems. The analysis found that Clinton's writing styles were influenced by the 'double bind' women face in politics, with a tendency to be pragmatic and avoid personal revelations.
Researchers at Nagoya University developed a micro-sized device that can detect the IDH1-R132H mutation in glioma tumors, enabling real-time identification of tumor margins during surgery. The device takes less than 15 minutes to produce results and requires only small sample sizes.
Researchers at Marshall University have discovered a peptide, pNaKtide, that can reduce oxidant stress and ameliorate experimental uremic cardiomyopathy. This finding has significant implications for treating patients with kidney disease, which affects millions of people worldwide.
A new imaging technique enables researchers to visualize chromatin's dynamic processes in live cells, revealing its organization and response to stimuli. This breakthrough offers insights into the complex relationship between chromatin and gene expression, with potential implications for understanding cancer development.
Researchers found that environmental factors like plant cover and floral density determine common urban butterfly species, while spatial properties influence rare species. Urban park design can encourage or discourage certain species, emphasizing the need for careful consideration of surrounding landscape and disturbance features.