Insilico Medicine will present new research data on geroprotectors, small molecules that mimic the young healthy state in old human tissues. The results are a result of a multi-year research program with multiple in silico predictions made using algorithms validated using data from many age-related diseases.
Researchers find evidence of two separate eruptions in the mid-13th and mid-16th centuries, and another in the 19th century, revealing a more violent history for the star system. The team uses NASA's Hubble Space Telescope images to track the movement of gas ejected by Eta Carinae.
Researchers found that retroviral genes are essential for placenta development and contribute to male muscle mass. In mice, the inactivation of syncytins led to a fusion deficit during muscle growth, resulting in smaller fibers and less effective regeneration in males.
Tropical Depression Madeline showed a small burst of strength with strong thunderstorms developing near its center. Cloud top temperatures indicated storms stretching high into the troposphere and generating heavy rain.
The study found that balancing selection increases immune system gene diversity, which leads to a higher frequency of harmful gene variants. This suggests that our genetic adaptation to new pathogens comes at a cost, allowing some high-risk gene variants to persist in the population.
A breakthrough study published in Nature reveals that the fine detail of DNA shape plays a crucial role in distinguishing X chromosome binding sites from other chromosomes. The researchers identified a specific sequence signature called PionX, which is selectively recognized by the dosage compensation complex, enabling gene regulation.
Scientists at the University of British Columbia have made a groundbreaking discovery that could lead to treatments for fibrosis in Crohn's patients. Researchers found a mutation in mice that prevented fibrosis after infection, targeting a hormone receptor responsible for stimulating part of the immune response.
Researchers tracked white-tailed deer east of Casper for eight years, finding that CWD drastically reduced annual survival rates, especially in females. The population declined 10% annually over the study period, which could lead to localized extinctions in less than 50 years.
The Human Factors and Ergonomics Society will focus on human-centered issues in cyber operations, including situation awareness, vigilance, task-switching, and training. Presentations will address human factors gaps in cyber defense and explore persuasion principles in phishing emails.
Researchers have developed a porous, highly compressive 3D graphene material suitable for bone implants, demonstrating its potential as a replacement for titanium. The technique uses spark plasma sintering to weld nanoscale graphene sheets, producing materials with high mechanical strength and biocompatibility.
Air quality monitoring data from 2005-2014 reveals significant variability in London's road pollutants. Despite improvements, some areas continue to exceed EU limits for nitrogen dioxide levels; however, other pollutants like fine particulate matter and black carbon have seen notable decreases.
Typhoon Namtheun is expected to make landfall in Japan's Kyushu island on Sept 3, with maximum sustained winds near 115 mph. The storm has a small eye surrounded by powerful thunderstorms and is moving north at 7 mph.
Researchers from Vetmeduni Vienna found that high food availability during the active season in summer contributes to a long life. Telomere length at the end of the experiment was directly correlated with food availability, revealing that a full belly rejuvenates the cells.
Researchers at the University of Pittsburgh have demonstrated pattern recognition in hybrid materials that can be integrated into clothing or used as a sensory skin for robots. The materials, powered by chemical reactions, recognize distorted patterns and can inform doctors about hand injury recovery or monitor cardiovascular activity.
Researchers at FAU have made a significant break-through in producing defect-free graphene directly from graphite at low costs. This achievement paves the way for advancements in semi-conductor and sensor technologies.
Gros has investigated the possibility of bringing life to planets with temporary habitability, proposing an automated gene laboratory on board a probe. The Genesis mission could be achieved within decades with interstellar unmanned micro spacecraft, potentially allowing for the development of complex life forms.
Researchers at TUM have developed molecular sensors from deep-sea jellyfish proteins to measure electrical activity in heart cells. This allows for the identification of specific cell types and improves disease modeling and drug testing.
Researchers found that patients with lower severity trauma have peaks in mortality probability around 14 and 21 days after admission. The study used the largest trauma database in Europe to analyze 165,559 trauma cases, including 19,289 with unknown outcomes.
Scientists have developed an ultra-fast spectroscopic technique to track the fate of charged pairs in polymer:fullerene blends used in plastic solar cells. This allows for a better understanding of mechanisms and design more efficient solar energy converters.
Researchers developed a new mathematical model to predict zoonotic disease outbreaks like Ebola and Lassa fever. The model incorporates spillover and stuttering transmission, enabling more accurate predictions and informing targeted public health strategies.
A study in rural Nepal found that poverty and lack of support are key barriers to institutional births, despite the known safety benefits. Only 30% of women had their babies in a hospital or health post, highlighting the need for targeted interventions to address socioeconomic and structural barriers.
Research published in Medicine & Science in Sports & Exercise found that babies born with a low birth weight are more likely to be rated below-average at school sports by their teacher at age 13. Those with a low birth weight were also less likely to participate in exercise and sports across adulthood, from ages 36 to 68.
Systems biologist Jan Philipp Junker and molecular geneticist Gaetano Gargiulo have each received a €1.5 million ERC Starting Grant to study cellular processes in zebrafish and glioblastoma, respectively. Their research aims to understand the mechanisms behind variable phenomena in developmental biology.
Researchers at University of Wisconsin-Madison have created carbon nanotube transistors that outperform state-of-the-art silicon transistors, achieving a current 1.9 times higher than silicon transistors. The breakthrough could pave the way for carbon nanotubes to replace silicon in electronic devices.
A longitudinal study of extreme preemies born between 1977 and 1982 found that they are four times more likely to develop dysglycemia than normal birth weight peers. By their early 30s, 26% of ELBW babies have abnormal blood glucose levels.
Tropical Cyclone Gaston has weakened significantly, with its eye disappearing and clouds pushed to the northeast. Warnings have been issued for several islands in the Azores, including Flores and Corvo, Faial, Pico, Graciosa, Sao Jorge, and Terceira.
Researchers investigate how exposure to chemicals inhibits metabolism of fatty and high-sugar foods, contributing to obesity. The team aims to understand how toxicants affect cytochrome P450 enzymes, potentially identifying new targets for pharmaceutical companies.
A genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes contributing to parasite fitness during human cell infection. The study also reveals a protein called claudin-like apicomplexan microneme protein (CLAMP) with a strong effect on the parasite's invasion of host cells.
Researchers found that group extinction significantly increases cooperation within groups, with contributions averaging 92% of the endowment. This effect persists even after removal of the selection mechanism, suggesting that the threat of group extinction is a powerful motivator for cooperation.
Researchers create a cooling textile that utilizes infrared radiation, allowing for efficient heat dissipation and reducing the need for air conditioning. The material is made from polyethylene and has various characteristics desirable in clothing material.
A recent study published in PLOS ONE suggests that climate change was not a primary driver of technological innovation among Stone Age humans. Researchers analyzed animal remains from South Africa's southern Cape, finding that human populations were able to absorb changes to the climate through resources like long-distance contact and ...
A new study identifies countries in Africa and Asia at greatest risk of Zika virus transmission due to climate, mosquito presence, and large populations. The analysis highlights India, the Philippines, Indonesia, Nigeria, Vietnam, Pakistan, and Bangladesh as top countries, emphasizing the need for public health decision-making support.
In a study published in Frontiers in Psychology, scientists found that wolves are consistently more prone to take risks when gambling for food than dogs. The researchers trained 7 wolves and 7 dogs to choose between a safe option and a risky option with uncertain rewards, and the results showed that wolves chose the risky option in 80%...
A Zika virus reference strain has been sequenced to aid in diagnosis and screening of the disease. The strain will be used as a World Health Organization reference strain to identify Zika virus infection in the blood, making it easier to diagnose the disease.
Researchers found that killer shrimps drove native amphipods out of hiding places, making them easy prey for round gobies. The invasive crustaceans played an indirect role in the decline of native species.
A new marine biodiversity study reveals the impact of glacial events on subantarctic seabed animals, providing insights into the extent of South Georgia's ice sheet during the Last Glacial Maximum. The research found that most seabed species have not moved far back to recolonize the coast despite having thousands of years to recover.
AAAS researchers have developed a new type of cloth that can reflect sunlight while allowing heat to radiate from the body, potentially reducing energy costs associated with air conditioning. The fabric, made from nanoporous polyethylene, passes 96% of infrared radiation through its pores, making it highly effective at keeping cool.
Researchers analyzed 4,500 US hospitals' data and found that facilities with high readmission rates had better mortality scores in specific conditions like heart failure, COPD, and stroke. This challenges the commonly used measure of hospital quality by CMS.
Hurricane Lester has moved into the Central Pacific Ocean, prompting new hurricane watches for Hawaii. The storm is expected to bring powerful thunderstorms and heavy rains to the islands on Saturday.
Researchers at Utah State University have developed a new tool to help wetland managers create healthier, more productive wetlands. The computer model suggests altering water levels in individual diked wetland units and focusing on invasive plant control at a specific time of year.
A Rochester Institute of Technology professor has received a $436,989 grant to study the efficacy of using the DapL enzyme in creating narrow-spectrum antibiotics. The research could lead to breakthroughs in targeting pathogenic bacteria and help combat the growing threat of antibiotic-resistant bacteria.
A recent study of science PhDs found that nearly two-thirds chose employment outside academic science, with reasons including autonomy, leadership roles, and high salaries. The researchers suggest that formal support networks could have provided an opportunity for URM PhDs to stay in faculty career paths
Researchers at the Boyce Thompson Institute have discovered a new receptor in tomato plants called FLAGELLIN-SENSING 3 (FLS3) that triggers defenses against bacterial attacks. FLS3 detects a part of the flagellum protein and helps tomatoes defend against bacteria with altered flagellin shapes.
A recent study published in the Journal for Healthcare Quality found that Democrats and Republicans have different views on the quality of healthcare, but those with recent illnesses had similar experiences. The research suggests that political differences in opinions about government regulation may contribute to these disparities.
The NIH review found that acupuncture, yoga, and tai chi are effective for managing back pain and osteoarthritis. Massage therapy and relaxation techniques also show promise in reducing severe headaches and migraine symptoms.
Researchers in Northwestern China report ongoing transmission of rabies, highlighting challenges in reservoir animals such as dogs and wild foxes. The study emphasizes the need for oral vaccines for these animals, citing limited evidence on vaccination dosing and scheduling.
A study by researchers at UW Medicine and Seattle Children's Research Institute found a link between exposure to diagnostic ultrasound in the first trimester of pregnancy and increased autism symptom severity. The study suggests that current FDA guidelines may need to be revised to account for this potential risk.
A recent University of Pittsburgh study found that parents' math skills are associated with their children's performance on standardized tests and may be influenced by an intuitive sense of numbers. The research suggests that parental influence can play a significant role in shaping children's mathematical abilities.
Tropical Storm Hermine strengthened and organized in the Gulf of Mexico, with intense storms detected by NASA's Global Precipitation Measurement mission. Rainfall rates reached over 9.9 inches per hour in powerful storms southwest of the storm's center.
The endangered North Atlantic right whale population is facing a dual threat, with lethal and debilitating entanglements on the rise and a dramatic decline in birth rates. The species' recovery success is now in jeopardy due to a lack of management intervention.
A unique health survey of Finnish cats has identified common health issues such as mouth, skin, and kidney problems, as well as nearly 60 breed-specific illnesses. The study provides valuable information for preventing disease and developing breeding programs, highlighting the importance of genetic research and improving cat welfare.
Researchers at Children's Hospital Los Angeles analyzed gene-disease findings to understand the co-occurrence of neurodevelopmental and mental illness with physical disorders. The study highlights the importance of a holistic approach to treating individuals, focusing on both physical and mental symptoms.
Researchers find that a widely available dengue vaccine could worsen the disease in some settings, particularly in low-transmission areas. The vaccine has shown to reduce illness and hospitalization by 20-30% in high-transmission countries but may increase these rates in locations with lower transmission.
A new study found that some living kidney donors are not given prompt access to transplantation when they need a transplant. The study examined data from the Organ Procurement and Transplantation Network (OPTN) and found that only 40-50 prior living donors are added to the kidney waiting list each year.
Researchers at UBC Okanagan campus develop synthetic heart valves made of polyvinyl alcohol hydrogel, reducing the need for animal tissues in bypass surgery. The new material allows surgeons to practice techniques in a more realistic and safe environment.
A recent study found that MirrorLink, a system allowing vehicles to communicate with smartphones, has significant security vulnerabilities. Hackers can exploit these weaknesses to control safety-critical vehicle components, posing a risk to driver safety and security.
Researchers at Colorado State University have demonstrated a new method for switching magnetic moments of electrons in a thin film of barium ferrite, a magnetic insulator. This breakthrough could lead to more efficient and lower power computer memory devices.
A study published in BMJ Open Sport & Exercise Medicine found a higher prevalence of heart abnormalities, including left ventricular hypertrophy, among triathletes who died during the swim portion of competitions. This suggests a plausible link between immersion pulmonary edema and swimming-related deaths in endurance athletes.
Researchers found that Holocaust survivors and their adult children showed opposite epigenetic changes in a stress-related gene, suggesting parental trauma may influence offspring biology. The study suggests clinicians should inquire about parental trauma in addition to personal trauma.
The collaboration will improve the sensitivity of the interferometric telescopes and enable the observation of smaller objects in the sky. The new system will allow astronomers to study high-interest targets such as dusty debris disks and accretion disks around newborn stars.