The University of Hawaii has received a nearly $6.3 million grant to develop a heat-stable, trivalent Ebola vaccine that can protect against three related viruses in the same family. The vaccine, developed by Axel Lehrer, PhD, has the potential to speed up protection for health workers and others during outbreaks.
A study published in JAMA Cardiology found that only 30.9% of patients prescribed PCSK9 inhibitors ever received therapy, largely due to copay costs and prior authorization processes. Patients with governmental insurance and those filled at specialty pharmacies were more likely to be approved.
A study of 11 addiction treatment professionals reflects the increase in prescription drug addictions and staff-related challenges following Hurricane Katrina. The disaster led to the creation of emergency preparedness plans, but participants expressed frustration with federal help conditions.
A study analyzing over 200,000 patients undergoing common surgical procedures found varying optimal opioid pain prescription lengths, with general surgery at 4-9 days, women's health at 4-13 days, and musculoskeletal at 6-15 days. The findings aim to balance adequate pain treatment with minimizing medication complications.
Researchers at Kyoto University have developed a more advanced radar-based device that can accurately measure the body's vital signals without attaching cumbersome wires. This technology has great promise for remote health monitoring and could potentially be integrated into household appliances to monitor residents' vitals.
Researchers discover two new crustacean species in deep waters off the northwest coast of Spain, both blind and measuring just a few millimeters. The species are distinct despite sharing their lack of eyes, with one belonging to the Photidae family and the other to the Corophiidae family.
Researchers developed a new approach to modeling pedestrian behavior in collisions, combining game theory with the Fokker-Planck equation. Experiments confirm that the calculated paths match actual paths taken, suggesting a reliable solution for optimizing public spaces.
Early iron intervention shows reduced aggression, rule-breaking behavior, and fewer thought problems in children at age 7. Cognitive abilities remain similar to those without supplements.
The partnership aims to address health disparities by conducting research on patient-derived cancers and training students in cancer health disparities-based precision medicine. This collaboration seeks to bridge the gap in understanding how to plan cancer prevention and care for underserved populations.
New research from Oxford University sheds light on the formation of the Earth and its depletion of vital chemical elements. By simulating early Earth conditions, scientists found that melting and evaporation played a key role in shaping the planet's chemistry.
A new study published in Acta Paediatrica indicates that survival rates for babies born weighing 500g are alarmingly low. Short-term morbidity is prevalent among surviving infants, with retinopathy of prematurity and chronic lung disease being common issues.
The partnership between genetic testing companies and orphan drug developers has both positive and negative implications. On the one hand, it can lead to faster diagnosis and treatment of rare diseases. However, there are also concerns over patient privacy and potential price-gouging due to rising healthcare costs.
A new project aims to discover how microplastics make their way from land to sea and what risks this contamination poses for various ecosystems. The researchers will also examine the impact on human health, environmental education, and develop strategies for sustainable preservation of aquatic ecosystems.
The OU research group, led by Ann West, has received a five-year, $10.5 million NIH COBRE grant to support structural biology research and build on Phase I successes with 57 research publications and over $7 million in new grants awarded.
Rensselaer Polytechnic Institute has received a $1.5 million training grant from the National Institutes of Health to support a new Alzheimer's Disease Clinical and Translational Research Training Program. The program aims to develop diagnostic tools, treatments, and potentially a cure for Alzheimer's disease.
A new study using Big Butterfly Count (BBC) data from citizen scientists shows that mass-participation science can provide additional assessments of biodiversity change. The results demonstrate the potential for citizen science to inform long-term monitoring of butterfly populations and complement standardised biodiversity monitoring.
Researchers at Argonne National Laboratory used the Mira supercomputer to simulate over 2,000 engine design combinations, reducing design time from months to weeks. The simulations identified two optimized fuel-engine concepts that can improve fuel efficiency substantially.
Researchers found that similar-achieving students tend to form close friendships, and this can lead to homogeneous social circles over time. The study's findings have important implications for understanding how social reproduction of inequality works in the digital age.
A newly-developed dipstick test sensitively identified Zika virus and all four dengue virus subtypes with no cross-reactivity. The test detected viral proteins at lower concentrations, making it a potential tool for diagnosing emerging pathogens.
Researchers at the University of Illinois Chicago are working on discovering new 2D materials to manufacture improved and cost-effective batteries. The goal is to increase battery efficiency by about 1,000 times, enabling sustainable energy generation, chemical manufacturing, and pollution removal.
A new study found that both restrictive spirometry pattern and reduced forced vital capacity were associated with increased arterial stiffness in men and women. Arterial stiffness increased fourfold when FVC decreased, highlighting the importance of assessing and following up on individuals with restrictive spirometry patterns.
A recent study published at Medical University of South Carolina found that epigenetic enzyme HDAC5 influences the brain's response to drugs, leading to persistent triggers for relapse. The research suggests that understanding these connections could lead to better treatments for addiction.
A UTSA researcher, along with collaborators, will study resilience in the LGBTQ+ population in San Antonio and South Texas. The project aims to address health and social needs, cope with discrimination, and develop strategies for marginalized individuals.
A computational study models the strength of basal ganglia connections between healthy and Parkinsonian brains, revealing a broad overlap in neural connection strengths. The research could lead to customized therapies specific to individual patterns of neural degeneration.
Researchers created photonic computer chips mimicking human brain's synapses, enabling speeds a thousand times faster than the human brain. The breakthrough paves the way for new age of computing where machines work and think like the human brain.
Research published in the European Respiratory Journal found that children under two years are more likely to be admitted to hospital with influenza if they have an older sibling. Vaccination can help reduce this risk.
A new paper-based test developed by MIT researchers can diagnose Zika infection within 20 minutes, accurately distinguishing it from Dengue virus. The test uses antibodies specific to Zika virus's NS1 protein, avoiding false positives common with existing tests.
RIT researchers, in collaboration with LIGO and Virgo, successfully triangulated the position of a 1.8 billion-year-old black hole merger. With three advanced detectors observing together, scientists can now pinpoint locations with higher precision, enabling more accurate electromagnetic counterparts searches.
Researchers propose a new potential way to produce initial compounds for many chemical industries, including pharmacy. The new method uses arylhydrazone complexes with Cu(II) and Co(II/III) catalysts.
Nerve cell networks reorganize themselves during periods of inactivity, becoming hypersensitive and prone to overreaction when signals are reinstated. Researchers developed a high-speed microscopy process to visualize communication networks of living neurons, shedding light on the effects of blocking neural pathways.
Scientists at the University of Warwick have identified tanycytes, key brain cells controlling appetite, which detect amino acids in food and inform the brain about fullness. Eating foods high in specific amino acids can activate these cells, leading to feelings of fullness and potentially aiding weight management.
University of Delaware researchers studied microbes from James Cameron's Deepsea Challenge Expedition, revealing a new branch on the microbial family tree. The Parcubacteria were found to have a simple metabolism but with extra features, indicating they may be able to perform anaerobic respiration and adapt to cold environments.
A new study by the University of Cambridge found that telephone consultations to determine whether a patient needs to see their GP face-to-face do not reduce GP workload or hospital referrals. Instead, they may increase overall GP workload and lead to increased secondary care costs.
Researchers found that Type I galaxies have more efficient supermassive black holes, emitting energy faster compared to Type II galaxies
A team of scientists at Beth Israel Deaconess Medical Center has identified a specific subset of neurons that respond to sodium deficiency, triggering an appetite for sodium. The researchers mapped the brain circuitry underlying this behavior and found that it is tightly regulated by hormones such as aldosterone and angiotensin II.
A new study found that early full-term births are associated with a higher risk of poor cardiorespiratory fitness during adolescence and young adulthood. The researchers also discovered that each week increase in gestational age is linked to a lower risk of poor respiratory fitness.
The NHS plans to sell off unused land to raise funds for essential maintenance and modernization of healthcare services. Kailash Chand, a GP, raises concerns that this approach may not address underlying shortfalls in the health budget and could lead to long-term costs.
A new animal movement model reveals seabirds orient themselves over an ocean and compensate for wind drift without landmarks, hinting at a 'map sense'. This breakthrough paves the way for analyzing animal decision-making using GPS tracking data.
A telephone-first approach to general practice reduced face-to-face consultations and increased telephone calls, but also led to an increase in emergency admissions. Despite its potential for managing some workloads, the approach was found to be associated with increased GP workload.
A study of 121 people with Parkinson's disease found that consuming three cups of coffee per day did not improve movement symptoms. The researchers concluded that caffeine cannot be recommended as therapy for movement symptoms of Parkinson's disease.
Researchers at LSU Health Sciences Center have discovered a new class of molecules called elovanoids that synchronize cell-to-cell communication and reduce inflammation in the brain. These novel molecules, made from omega-3 fatty acids, protect neuronal cells and promote their survival.
A new study from Harvard T.H. Chan School of Public Health reveals that extracellular vesicles (EVs) can carry receptors for intercellular communication, allowing signaling without direct cell-to-cell contact. This capability makes EVs uniquely suited to be engineered to send therapeutics directly to affected areas.
New study reveals integrated HBV DNA as a significant source of HBsAg, expanding understanding of HBV biology and host interactions. The findings have important implications for future trial design and endpoint expectations for new therapies developed to cure chronic HBV.
Research by University of New South Wales scientists finds that even a 1.5°C temperature increase will lead to longer and more frequent heatwaves globally. Tropical regions are expected to experience almost constant heatwaves with just a 2°C rise, while others may become unliveable if temperatures increase by 5°C.
A research team led by Ingi Agnarsson discovered 15 new species of smiley-faced spiders in the Caribbean region, challenging previous assumptions about a single widespread species. The study highlights the importance of good taxonomy and conservation biology in protecting biodiversity.
The Children's Tumor Foundation and PLOS ONE are collaborating on a new funding program in neurofibromatosis (NF) research, integrating the Registered Reports model to enhance rigor, reproducibility, and transparency. The partnership aims to accelerate transparent science and eliminate publication bias.
Two new species of bird-catcher trees from Puerto Rico have been discovered and named after Frances W. Horne and Ana Roque de Duprey, unrecognised women who devoted decades to educational projects in botany. The research highlights the importance of these trees thriving in well-studied areas like the Luquillo Mountains.
Researchers at Notre Dame's Harper Cancer Research Institute have made a breakthrough in understanding how ovarian cancer cells spread throughout the body. They found that a specific membrane proteinase called MT1-MMP plays a crucial role in regulating the transition of cancer cells from floating to sticking phases.
Dr Anja Osei's project aims to evaluate parliamentary debates and surveys among Members of Parliament in seven African countries to understand the role of parliaments in autocracies. The research will explore whether legislatures enhance democracy or contribute to authoritarian rule.
A study published in Springer's journal Sex Roles confirms that women consistently perform more housework than men, despite variations in life stages and circumstances. The research highlights the importance of time, money, and gender in shaping domestic labour, with women often bearing the brunt of household tasks.
A Michigan State University study found that preschool teachers lack knowledge and confidence in teaching science, contributing to the US poor global performance in this subject. Only high-skilled teachers created quality scientific opportunities for students.
A new study published in the Journal of the American Medical Association found that genetic testing can help set safe doses of common blood thinner warfarin. The study showed that patients who received warfarin dosing guided by their genetic makeup had a 27% reduction in adverse events, including bleeding and blood clots.
Researchers have developed a novel route to produce polyamide 6 by catalytically oxidizing cyclohexane with ferrocene in an ionic liquid medium. The process is highly selective and efficient, achieving over 98% selectivity and high turnover frequencies. This method has the potential to replace traditional industrial production processes.
Researchers from Kiel University discovered that small molecules secreted by nerve cells influence the composition and colonization of specific types of beneficial bacteria in Hydra. The study found that these neuropeptides have antibacterial activity, which affects the balance of the microbiome.
Glycosylation of smoke-derived volatiles in grapevine is catalyzed by a promiscuous resveratrol/guaiacol glucosyltransferase, leading to undesirable aromas in wine. The study provides insight into the molecular mechanism behind this phenomenon and potential counter-measures for vintners.
Scientists found anchovies and sardines spawning earlier and longer in Northwest waters due to unusually warm ocean conditions. This change may have unforeseen consequences on the food web, including competing with other species for food.
Researchers found that formula-fed or cesarean-delivered infants had altered bacterial colonization trajectories compared to vaginally-born and breastfed babies. This could have implications for their future health, particularly in the development of food allergies.
New simulations led by PPPL provide positive news for ITER. Researchers estimate a heat flux width of up to 6 millimeters within the divertor plates' capacity to tolerate, far greater than previous projections. This finding indicates ITER can produce 10 times more power than it consumes without damaging the divertor plates prematurely.
A study found that nearly three-quarters of medical professionals improperly share log-in credentials to access electronic medical records (EMRs), compromising patient data. Researchers recommend improving access credentials management and granting maximum privileges for one-time use to reduce password sharing.
A 70-year analysis of Danish data reveals a clear connection between nitrogen utilization and groundwater quality. The study found that reduced nitrogen applications lead to lower nitrate concentrations in groundwater, suggesting that economic growth can be achieved without negative environmental impacts.