Researchers discovered that our chromosomes age along with us, affecting how our immune system renews itself. In young people, thousands of gene sites are open, while in older adults, these sites become closed, leading to decreased activity in genes and pathways critical for defending against disease.
Chronic hepatitis B and C cause life-threatening liver damage, cancer, and premature death, with 300 million infected worldwide. Donors are essential to deliver results in the next 13 years, as domestic funding is unlikely to meet the challenge.
A Norwegian research team found that energy efficiency labeling for homes has no significant effect on purchase price. The researchers conducted a thorough analysis of home sales data before and after the labeling system was introduced in Norway in 2010. They discovered that any apparent impact of the label was likely due to other fact...
The Cleveland Clinic has been awarded a 5-year, $2.6 million grant from the National Cancer Institute to create innovative models of colorectal cancer. The project aims to better understand how the disease develops and spreads.
Researchers aim to integrate advance care planning into nursing home workflow to support decision-making for dementia patients and their families. The multistate project will evaluate the effectiveness of a pragmatic program that helps staff identify patient goals and values.
A study published in PLOS Medicine found that removing weekend allied health services from hospitals had no significant effect on patients' length of stay or adverse events. In fact, having no services was associated with a 2% reduction in length of stay and a 3% decrease in adverse events.
The City College of New York has received a $174,895 NSF RAPID grant to investigate the impacts of post-hurricane land-atmosphere interactions on convective and precipitation processes in the Caribbean region. Researchers will conduct field studies in Puerto Rico to improve their understanding of storm development and intensification.
A research team has discovered a technique called Accelerated Evolution that rapidly generates valuable natural products by mimicking bacterial evolution processes. This breakthrough could lead to hundreds of new compounds and revolutionize natural product drug discovery.
UNC researchers discovered that high-intensity shear shock waves amplify deep inside the brain, delivering a tenfold increase in tissue-ripping acceleration. This phenomenon may explain why some head knocks cause more harm than others.
Researchers at Stanford University developed a platform called Abuzz that uses cellphone recordings to track mosquito populations and distributions. The platform aims to create the world's largest network of mosquito surveillance, enabling targeted control efforts and reducing the burden of mosquito-borne diseases.
A RUDN University researcher found that plant root secretions stimulate microbial activity, leading to faster decomposition of organic matter and increased nutrient availability for plants. This has significant implications for long-term carbon accumulation and soil fertility in paddy soils.
A $10 microchip can be mounted onto a traditional ultrasound probe, providing 3-D imaging abilities similar to CT scans or MRIs. This technology has the potential to improve patient care, especially in emergency medicine and trauma cases where CT scans are not available.
A new study of over 80,000 adults found that strength-based exercise reduced the risk of premature death by 23% and cancer-related death by 31%. The research suggests that governments and public health authorities should promote strength-based guidelines to encourage long-term health and wellbeing.
NGTS-1b, the largest planet compared to its companion star, has been discovered by an international collaboration of astronomers. The giant gas giant orbits a small star half the size of our Sun and challenges theories on planet formation.
A new study found that future volcanic eruptions could lead to surface cooling of up to 40% due to the oceans' decreased ability to moderate the climate impacts. The increased cooling would disrupt the water cycle, decreasing global precipitation.
A survey of UK doctors reveals that workload pressures are a primary motivator for early retirement, particularly among GPs. Reducing bureaucratic burdens and shortening working hours could help retain senior doctors' expertise, which poses significant challenges for the medical workforce.
A study by Ohio State University found that upwardly mobile blacks and Hispanics experience more racial discrimination than their socioeconomically stable peers. This discrimination may be linked to poor health outcomes among young adults of color. The research suggests that addressing poverty alone is insufficient to eradicate health ...
Using computer models, researchers analyzed epigenetic marks to predict how chromosomes fold in three dimensions. By training a neural network on these marks, they were able to identify the structural types of chromatin and validate their findings with additional data.
A new study found that high levels of thyroid hormone FT4 are associated with an increased risk of artery disease and death. Researchers analyzed data from 9,420 participants and discovered a significant link between thyroid function and atherosclerosis.
INRS is upgrading its research facilities to study geological reservoirs, monitor hydrocarbons around sea ice, and understand chemical bonds, thanks to a $12 million investment. The new Multidisciplinary Tomography Centre will provide access to comprehensive non-destructive analysis tools.
A new study published in the International Journal of Astrobiology suggests that aliens could have evolved in a similar way to humans, with natural selection playing a key role. The research uses evolutionary theory to predict the biological make-up and behavior of complex alien life forms.
SourceData provides a suite of tools to generate, validate and use figure data, making it efficient to find and reuse published results. The platform links figures to other related figures across papers and journals, creating a searchable knowledge graph.
Research published in Gut found a significant association between long-term proton pump inhibitor (PPI) use and an increased risk of developing stomach cancer. The study, which monitored over 63,000 adults, revealed that the longer PPIs were used, the greater the risk, with daily use linked to a quadrupling in risk compared to weekly use.
A new study from Penn researchers shows that a reflexive system of the human eye also produces a conscious, visual experience that may be related to excessive light sensitivity. The findings suggest that people have brain activity and a visual experience in response to invisible light pulses that stimulate melanopsin cells.
Researchers at ETH Zurich generate the world's shortest controlled laser pulse with a duration of 43 attoseconds, allowing for unprecedented time resolution in studying molecular dynamics. This breakthrough enables faster charge transfer and potentially more efficient solar cells.
A new approach to detecting dyslexia has been developed by associating auditory processing in children with their reading skills. The study found that children who had difficulty processing low-frequency sounds were more likely to have reading problems and may be at risk of developing dyslexia.
The CULPRIT-SHOCK trial found that culprit lesion only percutaneous coronary intervention (PCI) reduces the composite of 30-day mortality and/or severe renal failure in patients with multivessel disease and cardiogenic shock. Immediate multivessel PCI was associated with higher rates of adverse outcomes.
The Transwomen Connected app aims to cater to the physical, mental and emotional needs of transgender women. The project will build a mobile app with HIV prevention tools and resources tailored specifically with their needs in mind.
Analyses of satellite sensing data show Red Sea's maximum surface temperatures increasing at a rate of 0.17°C per decade, four times faster than the global ocean warming rate. This rapid warming poses a threat to marine biodiversity in the region.
Eating high-pesticide residue fruits and vegetables was associated with lower probabilities of pregnancy and live birth following infertility treatment. The study found no negative association with low-pesticide residue intake, suggesting a possible link between pesticide exposure and decreased fertility outcomes.
Mice subjected to a calorie-restricted diet experienced improved skin and hair health, including increased fur production and reduced body fat. Skin vascularization also changed, with more blood vessels and increased blood flow to skin cells.
A VIMS study suggests that a common measure of fish health can help gauge the overall health of the Chesapeake Bay. The researchers found that annual trends in fish condition were surprisingly consistent among diverse species, with correlations between condition and changes in water quality, food availability, and climatic factors.
Vasanthi Jayaraman receives Maximizing Investigators' Research Award to study brain cell communication, developing high-resolution images of glutamate receptors for potential drug targets. Her research aims to enhance learning and memory, treat neurodegenerative conditions like Lou Gehrig's disease.
Experts say social media data use needs stricter guidelines due to rapid technological advancements and lack of adequate ethics frameworks. Researchers are mining large datasets to uncover insights into human behaviour, but only a small fraction report considering the ethical implications.
Studies found that female athletes in track and field experienced more bone stress injuries and tendon abnormalities than other Olympic events. Researchers recommend early MRI imaging for early detection of bone stress reactions and pre-competition screening data for chronic lesion detection.
A recent international study found that breastfeeding for at least two months significantly reduces the risk of Sudden Infant Death Syndrome (SIDS) by almost half. This finding suggests that any amount of breastfeeding provides some level of protection against SIDS, regardless of whether it's exclusive or partial.
Researchers at NASA's Goddard Space Flight Center are developing a highly compact infrared microbolometer camera called ComCAM to study near primitive objects. The device has the potential to assist in the redirection or possible destruction of an asteroid on a collision course with Earth.
A University of Delaware research team is studying how people adapt to power outages and water shortages after disasters. The project aims to optimize risk management strategies and improve societal needs through a multifaceted approach combining engineering modeling techniques, social science methods, and real-world case studies.
A new study finds that reducing greenhouse gas emissions to protect future generations from environmental destruction could save tens of billions of dollars annually, especially in wealthier countries. By valuing human population differently, policymakers can make more informed decisions about climate policy.
Researchers analyzed over 600 drug and breast cancer cell pairings, revealing significant changes in gene expression without affecting cell growth or survival. The study identified potential synergistic combinations of drugs, including trametinib and alpelisib, to overcome adaptive resistance mechanisms.
Tropical Storm Philippe developed from Tropical Depression 18, moving northeast through the Gulf of Mexico to Florida's east coast before merging with a frontal system. The remnants of Philippe dissipated over the western Atlantic Ocean, losing tropical characteristics.
A new method of carbon footprinting for pasture-based cattle production systems can identify 'green' cattle within a herd, reducing greenhouse gas emissions. The study found that existing methods underestimates the impacts of poorly performing animals, which produce disproportionately large amounts of methane.
Researchers at RIT suggest that outer gas disks of big spiral galaxies are suitable for hosting orbiting black holes and merging massive black holes. This discovery could help explain how black-hole pairs form and provide a new way to study the universe using gravitational waves and traditional light measurements.
The US Renal Data System report highlights the high burden of kidney disease in the US, with over 30 million adults affected, and a significant cost to healthcare. However, there is low awareness about the condition among patients, especially those with early stages of CKD.
Researchers at the University of Zurich have discovered a crucial mechanism for epigenetic gene regulation, involving the DNMT3A enzyme. This finding provides new insights into the development of aggressive types of leukemia and may lead to more effective treatments.
Researchers at UNIST have developed a novel hydrogen isotope separation system based on porous metal organic frameworks, exhibiting the highest selectivity to date. The system can efficiently separate and store deuterium, with a separation factor of 26, making it more cost-effective than cryogenic distillation methods.
Researchers at North Carolina State University have discovered that applying low voltage to gallium indium can induce the formation of unique fractal patterns. The discovery has significant implications for controlling liquid metals, as it allows for reversible and effective manipulation of surface tension.
Researchers found that insects reared on contaminated diets or irrigated with antibiotics exhibit increased mortality rates and altered development times. This study has implications for integrated pest management and the use of reclaimed wastewater in agriculture.
A systematic review of 242,731 traumatic brain injuries in baseball and softball found poor helmet use and return-to-play guidelines. The study recommends mandatory helmet use, education, and economic incentives to reduce preventable injuries.
A recent NIH-funded study used innovative NeuroGrid technology to show that sleep boosts communication between the hippocampus and association neocortex, crucial for memory formation. The research suggests that neural dialogue between these regions helps retain information during sleep.
A University of Queensland researcher suggests that conservation burials, where burial fees support threatened species conservation, have substantial potential to increase biodiversity. By generating revenue exceeding the cost of saving all threatened species, conservation burials could effectively protect endangered wildlife.
A population-based study found a 22% reduction in stomach cancer risk among those aged 60 and over who received antibiotic-based treatment for H. pylori infection compared to the general population. The study suggests that treating this type of bacterial infection in older adults can help reduce their risk of developing gastric cancer.
A tsunami in Hawaii's Kona Coast provided a rare glimpse into underwater soundscapes without human disruption, revealing that boat traffic and sonar exercises create the loudest disruptions in bays. This study validates concerns about human noise pollution disrupting dolphin sleep patterns.
Researchers have developed a CRISPR-Cas9-based gene drive platform to create diploid strains of C. albicans, allowing for the efficient deletion of genes involved in drug resistance and biofilm formation. The approach identified synergistic combinations of genes that contribute to these traits.
A new early warning system called Y-Ware is being developed to alert farmers to the risk of disease among their young cattle stock, aiming to improve health and welfare while reducing antimicrobial use. The project utilizes machine learning techniques and real-time data from sensors to provide an early warning system for health.
Researchers found that microscopic defects in electrodes enable lithium to hop inside the cathode along multiple directions, increasing reactive surface area and allowing for more efficient exchange of lithium ions. This discovery challenges traditional thinking on how electrode shape should be optimized for battery performance.
A large NIH-funded clinical trial will determine if bone marrow transplantation can be part of standard care for patients with severe sickle cell disease. The study aims to balance health risks with the promise of being cured, and participants will be followed for two years.
A study published in Population Health Management found that state-level Medicaid expansion improved health care access among low-income US residents, increasing insurance coverage and reducing barriers to care. Residents in non-expansion states were disproportionately negatively affected by the decision not to expand Medicaid coverage.
Rice University scientists invented a bifunctional recognition system called NanoDeg to target specific proteins and regulate their degradation. This plug-and-play system allows for precise control over protein expression levels, enabling the study of cellular dynamics and synthetic gene circuits.
The new guidelines aim to prevent sudden cardiac death in patients with ventricular arrhythmias. The guideline recommends the use of implantable cardioverter defibrillators (ICDs) and provides guidance on genetic counseling and testing.