A new study found that parents who acknowledge their adolescent children's perspectives and encourage them to express themselves have youths with stronger self-worth, intrinsic motivation, and engagement. However, the benefits of autonomy and decision-making differ across cultures.
Researchers have developed a new medicine, tarloxitinib, that brings high doses of anti-EGFR drugs to tumors while keeping toxic levels in healthy tissues. The prodrug-based approach has shown promising results in tests against lung cancer cells with EGFR exon 20 insertions.
Researchers evaluated the impact of eating dried cranberries on gut microbiome health, finding positive but statistically insignificant changes. The study's findings motivate further exploration into the role of dried cranberries in whole-body health.
Researchers from Lancaster University found that teenagers who do not access healthcare when needed are at greater risk of dropping out of high school. More than one in five young people globally experience this issue, leading to increased unemployment, poor health, and crime.
Researchers will count and catalog cell types in mouse brain using single-cell transcriptomics, aiming to build a comprehensive atlas of cell types that can be applied to the human brain.
Scientists from Boston College and Harvard have successfully created a copper iridate metal oxide that meets the Kitaev model's standards, enabling a chemical entity known as a 'spin liquid' with free-flowing properties. The material's unique honeycomb structure disrupts natural magnetic order, producing geometric frustration.
A study by Oakland trauma surgeons found that acoustic gunshot sensor technology can lead to quicker hospital arrival times and equal survival rates despite more severe injuries. The technology detects gunshots and provides responders with accurate information, helping paramedics treat and transport patients faster.
The New York Stem Cell Foundation (NYSCF) has selected six promising researchers and neuroscientists to join the NYSCF - Robertson Investigators program, providing critical seed funding of $1.5 million over five years. The program supports high-risk/high-reward research that aims to accelerate treatments and cures for various diseases.
Lehigh University engineers developed an optimization model, IADSS, which streamlines the assignment of inmates to Pennsylvania's 25 correctional institutions, saving millions and reducing recidivism. The system has been credited with achieving cost savings in four areas: treatment programs, prison assaults, staffing, and transportation.
The Society of Nuclear Medicine and Molecular Imaging (SNMMI) has published appropriate use criteria (AUC) for FDG PET/CT imaging in cancer patients. The AUC aims to improve the utilization of this technology and provide guidance for providers across specialties.
Dr. Paul Tesar receives the 2017 NYSCF Robertson Stem Cell Prize for his pioneering work on pluripotent epiblast stem cells, which holds promise for treating neurological disorders like multiple sclerosis and pediatric leukodystrophies.
A study by researchers at the University of Basel and FMI identified specific neuron types in the brainstem that regulate high-speed locomotion. These neurons are intermingled with others that can elicit immediate stopping, and their activation can induce full body locomotion.
A team of FSU scientists outlines a methodology that uses rainfall rates to mark the span of the Indian Summer Monsoon. The new system has been shown to capture ISM evolution comprehensively, enabling easy real-time monitoring.
Researchers develop algorithm to transform healthy and diseased cells into desired cell types, leveraging gene expression and transcription factor data. The approach aims to regenerate tissue and fight cancer, offering a shortcut to traditional cell transformation techniques.
The US FDA has awarded a grant to I-ACT for Children to establish an alliance among leading institutions and health systems to address gaps in pediatric clinical trials. The network aims to improve the efficiency of trials through innovative design, operational efficiency, and stakeholder engagement.
Researchers from NUS have developed a novel organic thin film that stores and processes data for 1 trillion cycles, significantly outperforming existing flash memory devices. The new device consumes 1,000 times less power and has the potential to be made even smaller.
Scientists have developed intelligent nanoparticles that can heat cancer cells to a high temperature, but then self-regulate and lose heat before causing harm to healthy tissue. This breakthrough could lead to a more effective treatment method for cancer patients.
Researchers analyzed blood and brain tissue data to find epigenetic marks that control gene expression, revealing key connections between genes and immune function. This study suggests that understanding epigenetic connections could lead to new treatments for autism by targeting specific biological pathways.
Tropical Storm Saola has strengthened to a tropical storm near Guam, with NASA's Aqua satellite analyzing its cloud top temperatures in infrared light. The storm is expected to continue strengthening and become a typhoon by Oct. 25, bringing strong winds and hazardous surf.
Kent State University professor Jonathan Maletic has received a three-year, $290,610 NSF grant to develop eye-tracking software that can track programmers' working environments. This project will enable more realistic studies of programmers' behavior, leading to better understanding of program comprehension and development.
Insilico Medicine showcases its use of artificial intelligence to identify disease targets, generate molecular structures, and track interventions for metabesity. The company aims to prevent metabolic-rooted disorders such as diabetes and dementia.
The pilot project identified significant bottlenecks in data sharing practices among IDRC-funded projects, including lack of resources, expertise, and tailored data management platforms. The study recommends empowering Program Officers with training and support to enhance policy implementation.
A new study analyzes Google Trends data across eight countries, finding summer and fall seasons correlate with greater hair loss. The findings provide evidence for seasonality in hair loss at a population level, supporting future research into the physiology of the hair cycle.
A new experimental drug has been found to block deadly muscle scarring that contributes to chronic heart failure and skeletal muscle disorders. The treatment targets alpha V integrins on scar-forming cells, reducing scarring even when the process has already started.
A team of scientists from UC Santa Barbara tested the effect of sulfurized nano-zero-valent iron on a common freshwater alga and found that it picked up cadmium and alleviated toxicity. Organic material produced by the algae mitigated the nanoparticle's toxicity, allowing for greater remediation.
A UK study aims to improve mental health identification in autistic individuals with learning difficulties, who face unique challenges. The research will develop an assessment tool to distinguish between anxiety/depression and physical health-related distress.
A new combination therapy using registered drugs albendazole and antibiotics has dramatically shortened treatment time for lymphatic filariasis and onchocerciasis, reducing it from weeks to just seven days. This breakthrough could accelerate elimination of these debilitating diseases, prioritized by the UN's Sustainable Development Goals.
The NIH BRAIN Initiative has launched a major effort to discover and catalog the brain's diverse cell types. The BICCN will generate knowledge that is prerequisite to solving the mysteries of brain disorders such as schizophrenia, Alzheimer's disease, and autism spectrum disorder.
A new study analyzes genetic material from people in Western Asia, identifying DNA sequences inherited from Neanderthals. The research suggests that this region is the most likely spot where humans first encountered Neanderthals, with implications for human health and well-being.
A University of Colorado Boulder study found more than 1,800 earthquakes in southern Colorado and northern New Mexico between 2008 and 2010 were likely caused by fluids pumped deep underground during oil and gas wastewater disposal. Elevated pore pressures in the basement rock underlie the Raton Basin's oldest stratified layers.
A study found that proton beam therapy in combination with chemotherapy prior to surgery reduces postoperative heart and lung problems and mortality rates in elderly patients. Researchers followed 571 patients treated with traditional radiation therapy and chemotherapy followed by surgery at Mayo Clinic Cancer Center.
Researchers at UBC Okanagan campus have created a definitive method to detect wildfire-tainted wine grapes, providing accurate and quick results. The new test detects volatile phenols present in the fruit prior to wine production, helping wine producers and grape growers manage the impact of smoke exposure on wine flavor.
A new study found that weight loss after bariatric surgery can lead to significant improvements in heart health, including a return to natural shape and function. The study also showed a decrease in ventricle size by 15.7 percent, reducing the risk of heart failure.
Human exposure to glyphosate has increased significantly since the introduction of genetically modified crops, with 70% of study participants having detectable levels by 2016. Glyphosate use has also increased 15-fold since 1994.
Researchers at Nara Institute of Science and Technology identified CRABS CLAW as a key molecule that controls the termination of stem cell growth and the formation of gynoecium in flowers, promoting floral reproduction. The study also shows auxin homeostasis is regulated by TORNADO2, providing insight into flower development.
A study published in Nature Communications has identified five genetic risk loci associated with food allergies in children, highlighting the importance of skin and mucous membrane barriers. The research, involving over 1,500 participants, also found that four of the five risk loci are linked to other chronic inflammatory diseases.
Researchers used a mathematical equation to analyze how our self-esteem is shaped by what others think of us. They found that self-esteem changes are guided by whether we expect to be liked and that increased prediction errors in the brain can confer risk for mental health problems.
A new study investigated the effects of domestic violence on workplaces by asking perpetrators, finding substantial negative effects on productivity and safety. The survey found that nearly half of respondents reported that violence issues negatively affected their job performance.
A new study reveals that children spontaneously practice skills from age 6, developing cognitive processes essential for expertise and lifelong learning. The study suggests improvements in episodic foresight, metacognition, and executive functions contribute to increased understanding of practice.
Researchers found that robot-assisted laparoscopic surgery for kidney removal had comparable patient outcomes but higher costs, with a 46.3% chance of prolonged operative time compared to traditional procedures.
Scientists at Columbia University Irving Medical Center have identified several compounds that selectively inhibit FOXO1, improving insulin sensitivity and reducing glucose production in the liver. These findings offer a promising approach to developing new, safer treatments for diabetes.
Dr. Juan Robles has received a $1 million grant to support Bronx students pursuing healthcare careers and create a more inclusive workforce. The program aims to bridge the cultural gap between doctors and their patients, which research shows enhances communication and trust with patients.
The opioid epidemic has reached crisis proportions, with nearly 90 opioid overdose deaths per day in the US. Anesthesiologists and pain medicine physicians can take a leading role in identifying and solving the issues by using non-opioid drugs and emerging treatments.
A new study suggests that increased screening by primary health care providers is yielding a bigger proportion of diagnoses, leading to more opportunities for treatment. The study found that the proportion of missed cases of diabetes dropped significantly over time, from 16.3% to 10.9%, and targeted screening in high-risk populations c...
A Japanese team has gained a deeper understanding of the electronic processes guiding liquid-to-glass transitions. By studying an organic metal material with 'frustrated' electrons, they revealed that rapid cooling can create glass-like states similar to conventional glasses.
A small study found that gut bacteria undergo significant changes within 72 hours of serious injury/trauma, which may impact recovery outcomes. These changes could be used to inform probiotic regimens or guide microbial composition shifts, potentially improving critical care outcomes.
A NIH study found that infant cries activate specific brain regions related to movement and speech in mothers worldwide. Consistent behaviors across cultures suggest hard-wired reactions to infant cries.
A UTA study found that more than 65% of residents living in the transit-dependent core of Dallas have limited access to jobs within a 45-minute commute time. The study also shows that households spend over 19% of their income on transportation, making it unaffordable for many residents.
Researchers from TU Graz developed the 'Lipid Data Analyzer' tool, which can identify lipids at a detailed structural level more precisely and reliably than previous solutions. The tool detected over 100 novel lipid species and can be flexibly adapted for other metabolic products such as sugars.
A new study found that patients with advanced cancer prefer face-to-face interaction with their doctors, with better communication skills and professionalism. After watching both videos, 72% of participants favored the face-to-face interaction, highlighting the importance of human connection in healthcare.
Researchers found that supplementing cell cultures with nicotinamide riboside protects cells and prevents malignant transformation. The compound may be used in chemoprevention to prevent cancer development.
Researchers analyzed 26 studies to find teams of friends outperformed groups of acquaintances or strangers on tasks requiring output maximization. Friendship groups coordinated tasks more effectively and were motivated by social interactions.
Researchers at the University of Cambridge discovered that the default mode network plays a crucial role in switching to 'autopilot' during familiar tasks. The DMN enables fast and accurate responses by leveraging memory associations, suggesting an essential function beyond mere daydreaming.
A new study published in JAMA Internal Medicine reveals that low wealth is associated with higher risks of death and disability among older adults in the US and England. Increasing wealth for those with the least can lead to gains in life expectancy and function.
Research reveals sleepwalkers have improved automation in movement control compared to non-sleepwalkers. They maintain speed and accuracy during tasks requiring conscious attention, indicating potential daytime markers for sleepwalking diagnosis.
A study by University of Illinois ornithologist Mike Ward found that 85% of Canada geese wintered in the Greater Chicago Metropolitan Area, with none making foraging flights to agricultural fields. The birds' ability to minimize risk by using urban areas suggests they are prioritizing survival over energy intake.
A 60-year study found a strong link between depression and an increased risk of death, particularly among women, who experienced a 50% increase in mortality risk between 1992 and 2011. Depression was also associated with shorter lifespan and lower life expectancy in young adults.
Scientists at Emory University School of Medicine have developed a method for generating endothelial cells from human induced pluripotent stem cells, which can survive for over 10 months when surrounded by a supportive gel. This breakthrough could lead to new treatments for peripheral artery disease.
A Keck School of Medicine of USC study found that teens vaping high-nicotine e-cigarettes were 14 times more likely to smoke traditional cigarettes per day. High nicotine concentrations increased the risk of becoming frequent smokers among youth.
The NIH BRAIN Initiative is expanding its efforts to develop new tools and technologies to understand neural circuit function and capture a dynamic view of the brain in action. Researchers are making rapid progress in visualizing the brain in action, identifying thousands of brain cells at a time, and developing innovative brain scanners.