A retrospective review of a UK national HCV database found that over one-third of young people with childhood acquired HCV develop serious long-term liver disease. The study highlights the importance of early detection and treatment to prevent long-term liver damage.
A study suggests that increasing women's access to education, reproductive health services, and contraceptive technologies is crucial for achieving sustainable development. Empowering women can help slow down population growth, reduce consumption of resources, and protect biodiversity.
The study found that sexual function declined after all treatments, with robotic surgery patients regaining function closest to brachytherapy and radiation levels. Urinary incontinence also decreased most for surgical patients, with robotic surgery showing slight improvement over open surgery.
In a global campaign, indigenous peoples and local communities from 25 countries are protesting and demanding recognition of their land rights to safeguard the world's forests and prevent climate change. The Land Rights Now initiative calls on governments and the private sector to respect secure land rights.
Researchers discovered that fats can tip the scales of fertility in roundworms by monitoring fatty acid levels using an enzyme called acyl-CoA synthase 4 (ACS-4). This phenomenon has implications for future studies into human fertility and reproductive development.
Researchers at Japan's National Institute of Genetics discovered a direct neural link connecting the brain's visual system to its feeding center, linking visual perception of food to feeding motivation. This study, using genetically engineered zebrafish, shows that 'eating with the eyes' is deeply rooted in evolution.
Researchers found that early mammalian ancestors enhanced their night vision genes, allowing them to thrive in the dark. This study supports existing fossil evidence and sheds light on the evolution of vision in mammals.
An international team of physicists and astronomers has detected for the first time multiple images from a gravitationally lensed Type Ia supernova. The observations suggest that this phenomenon can be used to test key cosmological theories about the accelerating expansion of the universe and the distribution of dark matter. By analyzi...
Researchers at Chalmers University of Technology discovered over 1000 pathways in fungi to produce natural and bioactive chemicals. The findings show vast potential for fungi to produce new antibiotics, efficient production of existing ones, and potentially more effective versions.
Research reveals that current or past stimulant use can lead to psychomotor control deficits, affecting everyday tasks. Heavy users experience persistent tremors even after months of detoxification.
Physicist Laurens Molenkamp has won an Advanced Grant from the European Research Council to study exotic superconductors in topological insulators. This project aims to explore their potential use in quantum computers.
A periodic time-delayed model of Lyme disease predicts its spread in North America and Canada, incorporating seasonality and climate factors. The model suggests that reducing tick recruitment rates can help eliminate the disease.
A gene in wild tobacco regulates the production of bergamotene, which increases pollination success and protects against herbivory. The compound is emitted at night to attract nocturnal pollinators, such as Manduca sexta moths.
A new architecture for 3D stacked memory increases rendering speeds by up to 65% by processing data in memory, reducing traffic between GPU cores. This innovation benefits both science, particularly complex modeling and virtual reality, and the gaming industry.
A novel dietary supplement has been shown to reverse cellular damage caused by specific genetic mutations in the kidneys of transgenic fruit flies. The study provides a personalized model for testing novel therapies for rare diseases such as focal segmental glomerulosclerosis (FSGS), which currently lack treatment options.
A study by Cornell University found that pesticides pose a significant risk to honeybees, with over 60% of found pesticides attributed to non-sprayed orchards and surrounding farmland. The research analyzed the bees' food stores and revealed high levels of pesticide exposure in 17% of colonies.
A review of psychoactive substance use among healthy individuals highlights potential cognitive enhancements, but also safety concerns and ethical issues. The study suggests that more research is needed to understand the long-term effects and develop harm reduction strategies.
Researchers at Nagoya University have discovered how plant parent genes cooperate to develop their offspring. The study shows that maternal and paternal factors work together to control the asymmetric division of the zygote, leading to the formation of roots or leaves.
Renowned researchers gathered to discuss stevia's health benefits, safety, and innovations in low/zero calorie sweeteners. Stevia was found to not alter during extraction and purification, providing evidence for its naturality, while research on its impact on blood glucose, diabetes, and overall health showed promising results.
Researchers have developed a new solution to tracking objects hidden behind scattering media by analyzing fluctuations in optical 'noise' created by their movement. The approach can advance real-time remote sensing for military and biomedical applications.
Research shows complex partnership between ear and brain can compensate for significant inner ear damage, leading to normal audiogram but difficulty hearing in certain situations. The study highlights the need for more challenging behavioral tests to diagnose patients with 'hidden hearing loss'.
Exposure to high temperatures in Caenorhabditis elegans can lead to genetic changes that persist through both sperm and egg, affecting up to 14 generations. These changes are driven by a temperature-induced reduction in an enzyme, resulting in gene expression alterations that 'remember' the environmental stress.
A leading conservationist warns that failing to celebrate conservation successes can lead to complacency and reversal of progress. Recent examples of species recoveries, such as the Brazilian golden lion tamarins and giant pandas, demonstrate positive shifting baselines in nature's recovery through conservation.
Researchers have identified the structure of NsrR, a bacterial protein that binds to DNA and plays a key role in resisting nitric oxide, a toxic byproduct of the human immune response. The study provides new insights into how bacteria counteract NO and highlights the importance of understanding this complex process.
Researchers have developed a malaria protein-based drug that demonstrates promising results against chemotherapy-resistant bladder cancer. The new treatment showed a dramatic response to the malaria drug combo, resulting in an 80% survival rate among treated animals.
Researchers found that patients with better consciousness levels had body temperature patterns aligned with a healthy 24-hour rhythm. Bright light stimulation improved two patients' conditions, and their circadian body temperature shifted closer to normal.
Researchers designed a new technology that uses machine learning to model personal sleep patterns based on recorded sounds made during sleep. This method allows doctors to diagnose patients under normal sleeping conditions, leading to better treatment outcomes.
A new study reveals that people with multiple sclerosis can show signs of the disease five years before its official diagnosis. Researchers analyzed health records from 14,000 patients with MS and found that they were more likely to visit their physicians and fill prescriptions earlier than others.
A new behavioral intervention program called HOLA en Grupos has been shown to increase condom use and HIV testing among Latino MSM, reducing the risk of infection. The program achieved a 100% retention rate and significant increases in knowledge and skills, providing a promising solution for addressing this growing public health concern.
A new study published in the journal Addiction suggests that cannabis use is associated with a lower risk of psychosis than previously believed. For patients with schizophrenia, cannabis exacerbates symptoms. Regulation of cannabis markets could help reduce health risks, particularly when combined with tobacco use.
Hydrogels, jelly-like materials with water-based properties, require a better understanding of their structure and mechanical properties. Professor Ullal will use super-resolution microscopy techniques to characterize the structure of hydrogels and develop new materials.
Scientists have created a global map measuring the cooling effect of forests by regulating water and energy exchange between the Earth's surface and atmosphere. This new statistical model allows communities to pinpoint ideal locations for forest protection or reforestation efforts.
A Phase 2 trial found rituximab not effective in treating fatigue in primary biliary cholangitis (PBC) patients, but showed improvements in anaerobic threshold. The study suggests further research on specific types of fatigue may yield more favorable results.
A DAA treatment combination, sofosbuvir/velpatasvir with or without voxilaprevir, shows significant improvements in patient-reported outcomes for patients with HCV and cirrhosis. The overall cure rate is 94% for patients with and without cirrhosis.
A recent study has discovered that macrophages are essential for the normal functioning of the heart, helping conduct electric signals that coordinate heartbeat. The findings suggest that changes in macrophage numbers or properties may contribute to heart rhythm abnormalities.
A new study published in PLOS Medicine suggests that stimulating the brain through leadership roles at work or staying in education can help people stay mentally healthy in later life. Engaging in activities that challenge the brain and build cognitive reserve can make it more resilient to illnesses such as dementia.
A recent study found that a mindfulness course significantly helped women overcome negative affect, while its effects on men were negligible. The study, led by Brown University researchers, suggests that mindfulness may be more effective for women due to their tendency to ruminate and process emotions differently than men.
Research finds elevated immune activation during treatment is not driven by low HIV levels in the blood. Pre-treatment immune events may contribute to continued activation despite antiretroviral success.
A new study finds that Antarctica's biodiversity is lagging behind the rest of the world in protected area management and bioprospecting regulation. The region faces threats from warming oceans, melting ice cover, and transnational pollution, despite some successes in invasive species management.
Researchers like Dr. Julie Pfeiffer are studying poliovirus, a highly infectious childhood disease now close to global eradication, to gain insights into other viruses like Ebola, Zika, and influenza. This basic research can lead to new treatments and vaccines for these viruses.
Researchers found that increased familiarity with a foreign accent leads to better sentence processing and trains the acoustic system to process accented speech. Listeners who correctly identified the accent responded similarly to grammar and vocabulary errors in both native and foreign-accented sentences.
A preliminary study suggests that removing Epstein-Barr virus-infected B cells and boosting the immune system may improve symptoms of multiple sclerosis. Three participants showed significant improvements, including one person with secondary progressive MS who was able to walk without assistance for the first time in 20 years.
Physicists at Caltech have detected a new state of matter, a three-dimensional quantum liquid crystal, which could play a role in ultrafast quantum computers. This discovery may lead to the creation of topological superconductors, addressing challenges in building quantum computers.
Naked mole-rats can survive for at least five hours without oxygen by metabolizing fructose, reducing their movement and slowing their pulse rate. This unique adaptation may lead to new treatments for patients suffering from low oxygen conditions, such as heart attacks and strokes.
A new study published in JCI Insights reveals that increasing SMOC2 levels in the kidney can initiate and continue kidney fibrosis, while reducing SMOC2 levels prevents it. Detecting SMOC2 in urine may help diagnose fibrosis, making it a potential biomarker for early intervention.
A new study reveals a rising trend in hospitalizations for hypertensive emergency but a decrease in hospital mortality rates over the last decade. The presence of acute cardiorespiratory failure, chest pain, stroke, and aortic dissection were key predictors of higher hospital mortality.
A survey by Nemours Children's Health System found that 64% of parents plan to use telemedicine for their child's care within the next year. Parents cite convenience and immediacy as top reasons for using telemedicine, with most rating the experience superior to in-office visits.
The American Society of Clinical Oncology will host its 53rd Annual Meeting, featuring more than 2,150 abstracts on various cancer topics. The meeting highlights recent breakthroughs in immunotherapy and precision medicine, with a focus on improving patient care and outcomes.
Astronomers detected four images of the same supernova, a rare find, due to precise alignment with a foreground galaxy. This extreme case of gravitational lensing offers opportunities to study Type Ia supernovae and their role in cosmology.
A University of Surrey-led study has developed a model to provide vital insight into controlling CMV infection, particularly in transplant patients and HIV/AIDS sufferers. The research identified four unique patterns of response and created a sophisticated mathematical model to predict therapy duration needed for viral clearance.
Researchers used 3D printing to create a model of a patient's lower spine, allowing for successful insertion of a catheter for spinal cord stimulation. The technique may provide additional information to improve access in cases where standard approaches prove difficult.
A new study from the University of Georgia finds that increasing water temperatures are responsible for the accumulation of nitrite in marine environments, disrupting ocean food webs. Nitrite can alter single-celled plants, affecting animals that feed on them, and lead to toxic algal blooms.
Scientists discovered that environmental changes can be passed on in the genes of tiny nematode worms for at least 14 generations. This phenomenon was observed in worms carrying a transgene array, which showed increased activity after exposure to warmer temperatures.
Researchers have developed tools to visualize and control bacterial activity in the gut, opening up new possibilities for therapeutic delivery. These tools enable precise control of bacterial gene activity in specific locations within the gastrointestinal tract.
A study of neuroscience papers from 2006-2015 reveals the most productive journals and contributing countries. Psychology and behavioral sciences have become popular research areas, while China's involvement has increased significantly, jumping from 11th to 2nd place in 2015.
Repeated C. difficile infections are associated with higher death rates, longer hospital stays, and increased healthcare costs in Scotland. The study found that patients with recurrent infections had more than double the risk of dying within two months of admission.
Yale researchers have developed a 'genetic scalpel' to regulate gene activity in the gut microbiome, enabling precise control over bacterial communities. This breakthrough tool may help understand the microbiome's impact on health and disease, including infectious diseases and behavioral disorders.
A new statistical model has been developed to help guide forest management decisions under climate change. The model uses future climate scenarios to produce more accurate predictions than previous methods, allowing for the design of strategies that mitigate climate change impacts on loblolly pine plantations.
A study found that radio advertising free ultrasounds increased pregnant women's modern medical care attendance in rural Uganda by 490%. The use of portable ultrasound machines helped detect serious anatomical problems and infectious diseases, leading to improved health outcomes.
Scientists at Massachusetts General Hospital have established a direct link between increased intestinal permeability and chronic inflammatory diseases. The study provides evidence that zonulin-dependent modulation of small-intestinal permeability enhances antigen trafficking, leading to the development of an inflammatory disease.