Researchers found that generic drug prices rose significantly when market competition decreased, particularly in lower-priced drugs. The study suggests understanding the connection between competition and price may help identify older prescription drugs at higher risk for price changes in the future.
A study of nearly 130 adolescent and young women with sports-related concussions found an association between concussion and abnormal menstrual bleeding patterns. The researchers observed a higher incidence of irregular bleeding among those with concussions compared to non-injured controls.
A study by Harvard University found a genetic 'switch' that controls the activity of a key skeletal gene related to height, which is also linked to an increased risk of osteoarthritis. The variant, more prevalent in Eurasian populations, favors shortness and is associated with lower GDF5 activity in growth plates.
Researchers from Instituto Gulbenkian de Ciencia discovered that two genes from baker's yeast can increase plant resistance to a broad range of toxic substances, enabling their growth in contaminated soils. Plants carrying the yeast genes grew significantly better than wild-type plants in contaminated soils.
A high-fat diet during pregnancy significantly increases breast cancer susceptibility in offspring for three generations, according to a Georgetown University Medical Center study. Genetic changes were observed in mammary tissue of high-fat diet progeny compared to control group's offspring.
Kyle O'Connell, a fifth-year Ph.D. student at UTA, received a $19,695 NSF Doctoral Dissertation Improvement Grants award to support his research on speciation in Sumatra using parachuting frogs. His project aims to test hypotheses about the formation of new species through genetic and genomic data analysis.
A new study reveals that most frog species descended from just three lineages that survived the mass extinction event, with rapid radiation occurring due to available environmental niches. The loss of dinosaurs led to the rise of trees and flowering plants, which in turn favored the evolution of frogs.
Tropical Storm Nanmadol was analyzed by NASA using Suomi NPP and GPM Core satellites, revealing a powerful storm with maximum sustained winds of 45 knots. The data showed an eye-like structure at the center of circulation and heavy rainfall rates exceeding 184 mm per hour.
A study funded by NIH found that 31% of SIDS infants had elevated serotonin levels in their blood, suggesting an underlying vulnerability to the condition. Researchers propose testing blood samples for serotonin to distinguish SIDS cases from other infant deaths, but caution that more research is needed.
A single genetic change linked to reduced human height is also associated with an increased risk of osteoarthritis. The variant has been positively selected in many human populations, suggesting it may have provided a survival advantage in colder climates.
Researchers linked mechanical properties of titin to animal size, revealing that larger animals had less stable proteins. By comparing ancestral protein sequences with fossil records, they estimated the weight of ancient mammals, birds, and tetrapods, finding them to be relatively small.
Researchers found no significant difference in pain intensity after radiofrequency denervation, a procedure that uses electric current to target nerve pain sources. The study involved 681 participants and included three randomized clinical trials assessing the effectiveness of the treatment for different types of low back pain.
Researchers have discovered significant differences in G protein-coupled receptor expression between humans and mice, highlighting the need for new approaches to develop effective diabetes drugs.
A new study reveals that tadpoles living in low-temperature environments are more susceptible to DNA damage from UV radiation. This increased risk can lead to mutations and cell death, contributing to the global amphibian extinction crisis.
A study reveals that childhood psychiatric disorders, such as ADHD and depression, significantly increase the risk of developing addictions later in life. The research highlights the importance of early detection and intervention for mental health problems.
The Damon Runyon Cancer Research Foundation has awarded four physician-scientists with over $1.8 million in funding to pursue cancer research. The awards provide critical support to enhance translation and clinical research, addressing the financial disincentives that often deter physicians from pursuing a research career.
Germany's health system has proven remarkably resilient, but faces challenges such as overtreatment and continuity of care issues. The country has the potential to be a strong partner in global health research, but must increase its financial commitment and expertise.
Researchers have overcome a fundamental theoretical limitation to design molecular diodes with a record-high rectification ratio of 6.3 x 10^5. This breakthrough enables the use of molecular diodes in applications that silicon diodes can't handle, potentially leading to cheaper and easier fabrication.
Researchers have developed a new technique that can characterize nuclear material in a location even after the material has been removed. By analyzing changes in valence electrons, they can determine the presence, strength, and type of radioactive material present.
Scientists have identified how cytokinin activates genes to regulate plant growth, allowing for stem cell establishment in grains like rice and corn. The study reveals the mechanism of type-B ARRs in regulating cytokinin response and growing shoots in tissue culture.
A new portable device can quickly detect markers of deadly sepsis infection from a single drop of blood, providing rapid point-of-care measurement of the immune system's response. The device correlates well with traditional tests and vital signs, offering potential for earlier detection and prognosis.
A new study from the University of Cincinnati found that wearing colored lenses, such as blue, green, red, and purple, can provide significant relief from photophobia in post-concussion patients. This innovative approach offers a practical and comfortable alternative to dark sunglasses, which may not be suitable for all situations.
Researchers analyzed lists of names to extract information on mobility, gender imbalance and nepotism. They found a decline in nepotism in Italy from 2000 to 2015, but noted that changes in the academic system and faculty retirements also contributed to this trend.
Researchers discovered a new mechanism for processing color information in honeybees, which could improve color constancy in imaging systems. The study found that the bees' ocelli contain two color receptors that can detect ambient light color, allowing them to discount naturally colored illumination and perceive true colors.
Researchers at the University of Cambridge have successfully grown artificial bile ducts in a lab and transplanted them into mice, offering new hope for treating liver diseases. The artificial bile ducts, known as biliary organoids, were grown using cell transplantation and tissue engineering technology.
Researchers studied the Sun using sound waves to find that its significant magnetic activity layer has grown thinner in recent years. This change is being investigated as a possible cause of unusual solar activity.
Contracting shingles significantly raises the risk of stroke and heart attack, according to a recent study published in the Journal of the American College of Cardiology. Patients with shingles are more likely to have common risk factors for cardiovascular events, such as high blood pressure and diabetes.
A 'brain training' game developed by researchers at the University of Cambridge improved memory in patients with mild cognitive impairment by 40% through episodic memory tests. The app's engaging gameplay and individualization also boosted motivation and confidence.
Metal-nitride nanowires show high sensitivity to light when arranged in nano-sized wires, but thermal effects significantly impact their performance at room temperature. Researchers have developed a detailed study to quantify the effect of photoinduced entropy on device performance.
A new study of almost 19,000 IVF treatment cycles reveals that the age of the male partner significantly affects live birth success rate. The study found a decline in cumulative incidence of live birth with increasing male partner age, particularly among women aged 30-35 and those over 40.
UNIST has received a $4.5 million ITRC project grant to develop a self-charging tracking device that can monitor wild birds and detect potential bird flu outbreaks. The new technology, called Mobile Tracker, is expected to provide early warnings and aid public health officials in preventing the spread of disease.
Physicists have successfully demonstrated topological superconductivity in β-Bi2Pd films, a crucial step towards fault-tolerant quantum computing. The researchers found that tuning the chemical potential can isolate topological surface states, revealing a promising candidate for topological superconductor.
Research suggests that exoplanets near cool, low-mass stars require strong magnetic fields to shield their atmospheres from harmful X-rays and extreme pressure. The study models CMEs in a cool star system and finds that most CMEs are trapped by the star's surface, posing a significant threat to planetary habitability.
Research on ostriches reveals a counter-intuitive effect of their double-kneecap, decreasing mechanical advantage in knee extensor muscles. The true purpose of this unique structure is still unknown, with potential roles including tendon protection and joint function improvement.
A new robot designed by Mr Mouad Mkamel and his team can extract scorpion venom without harming the animal or risking life-threatening electrical shocks. The VES-4 device uses electric stimulation to collect venom droplets, which are then stored safely, offering a safer alternative to traditional manual methods.
Researchers at Mount Sinai Hospital have developed a novel technique to continuously monitor laryngeal and vagus nerve function during otolaryngology and neurosurgery procedures. This non-invasive method uses a special breathing tube to stimulate and record nerve responses, allowing surgeons to adjust their approach in real-time.
Patients with right-sided primary tumours have a 36% better survival rate after treatment with a combination of first-line chemotherapy and selective internal radiation therapy, compared to chemotherapy alone. This treatment combination was no better than chemotherapy only in patients with left-sided primary tumours.