Researchers found that grape-based compounds resveratrol and grape seed extract effectively killed colon cancer cells and suppressed tumors in mice. The combination of these compounds was found to be non-toxic to healthy cells, making them a promising approach for colon cancer prevention and treatment.
Researchers analyzed national health statistics to understand demographic differences in diabetes rates and care sought. The study found that people with lower income or lower educational levels had a higher prevalence of diabetes, with American Indians and Alaska Natives having the highest rates.
Researchers at Tel Aviv University develop new DNA delivery technology to neutralize lethal activity of drug-resistant bacterial pathogens. The innovation expands the range of bacteriophages, enabling manipulation and potentially leading to the development of new drugs.
Researchers developed a new brain stimulation protocol using repetitive transcranial magnetic stimulation (rTMS) and excitatory intermittent theta burst stimulation (iTBS), which showed significant benefits in reducing spasticity in spinal cord injury patients. The study found that improvements persisted even after the treatment ended.
Researchers found that yellow soybeans result from naturally occurring gene silencing involving two genes, which blocks production of darker pigment's precursors. The study also identified the Argonaute5 gene responsible for saddle-patterned beans, shedding light on epistatic interactions in soybean genetics.
A nationwide survey of hospitals, eldercare facilities, and therapy animal organizations reveals gaps in health and safety policies for therapy animal visits. Many facilities lack proper guidelines for animal health, behavior, and hygiene, posing risks to both humans and animals.
A new study reveals how mass wildebeest drownings impact the ecology of the Mara River. The research found that wildebeest carcasses provide a rich source of nutrients to the river's food web, supporting fish and scavenger populations. This subsidy delivers terrestrial nitrogen, phosphorus, and carbon to the river.
A recent study found that domesticated cats descend from the African wildcat or Felis silvestris lybica subspecies. The origins of cat domestication are attributed to the Near East and ancient Egypt around 10,000 years ago, where farmers welcomed wildcats to control rodents.
A new mathematical model developed by researchers at the University of Alberta predicts HIV growth and progression in the brain, revealing a viral reservoir. The model enables scientists to backtrack the development of HIV infection, informing treatment strategies and potential nasal spray therapies.
A new study found that HIV-1 infected cells can persist in the body for decades by exploiting normal cell proliferation. The research identified a single infected CD4 T cell that can amplify the number of virally infected cells through clonal proliferation, leading to a million-fold increase.
Scientists at Berkeley Lab demonstrated how particles synchronize in response to acoustic waves, exhibiting a phononic bandgap that emerged only when collectively organized. The study provides a simple platform to study non-equilibrium systems and could lead to the development of intelligent networks with sentient-like decision making.
States that expanded Medicaid coverage saw a 2.5% increase in emergency department visits per 1,000 people after 2014, while uninsured ER visits decreased by 5.3%. The study found larger impacts on states with higher childless adult populations.
A novel smartphone application has been developed to direct first responders to cardiac arrest victims more than three minutes before emergency services arrive. Each minute of earlier intervention increases the chance of survival by 10%, reducing brain injury risk.
Researchers have found that wheat middlings and red dog, two coproducts of the wheat milling process, have varying levels of protein digestibility when fed to pigs. The study suggests that red dog contains more easily digested amino acids due to its lower fiber content.
A new study published in The Journal of Neuroscience found that adolescent mice fed a poor diet lacking omega-3 fatty acids showed increased anxiety-like behavior and poorer memory performance as adults. The study suggests that adequate nutrition during adolescence is crucial for brain refinement and function.
A recent study reveals that the Asian summer monsoon significantly contributes to aerosol formation in the Northern Hemisphere's lower stratosphere, with a 15% annual contribution. The anticyclonic Asian monsoon serves as an efficient smokestack venting aerosols to the upper troposphere and lower stratosphere.
A new study published in PNAS argues that achieving net-zero carbon emissions requires a diverse portfolio of clean energy technologies beyond wind, solar, and hydroelectric power. Experts emphasize the importance of a broader approach to decarbonization, citing technical challenges and infrastructure realities.
Ticks use specialized pads on their feet to adhere to surfaces, allowing them to walk and search for prey on humans and animals. Their attachment mechanism is reversible and can be folded and unfolded like an accordion.
A study of 320 predominantly low-income, racially diverse adults with chronic low back pain found that yoga was as safe and effective as physical therapy in restoring function and relieving pain. Yoga and physical therapy groups showed similar improvements at 1 year, suggesting a reasonable alternative for patients.
Scientists have found that pericytes, strong contractile cells forming blood vessels, can also produce tumors and enable their spread. GT198, a gene normally expressing stem-cell like properties, becomes an oncogene when mutated, promoting cancer growth.
Researchers discovered how dying cells alert neighbors to replace them, a process called compensatory proliferation signaling (CPS). Specialized vesicles containing the CrkI protein travel to neighboring cells and cause them to create new cells.
A new ultrasound scoring system has been developed to identify thyroid nodules that require biopsy or follow-up. The system uses a risk stratification approach to classify nodule appearance and size, reducing unnecessary biopsies and improving cancer diagnosis accuracy.
Researchers at the University of York and Leeds have made a major discovery in Hepatitis B Virus assembly, paving the way for new drug treatments. The team identified an 'assembly code' in the genetic material that allows the virus to create a protective casing.
The study found that wildebeest carcasses play a crucial role in the ecosystem, providing food for various animals and supporting fish populations. The nutrient-rich carcasses also decompose over time, releasing phosphorus that supports algae, insects, and fish.
A study found that acetaminophen is effective in preventing acute mountain sickness, with no significant difference in incidence and severity compared to ibuprofen. The study suggests that acetaminophen may be an alternative prophylactic treatment for AMS, potentially offering fewer side effects.
Researchers found that probiotics can improve immunity in fruit flies exposed to pesticides, a common model for studying honey bee effects. This mechanism could lead to improved survival rates for honey bees exposed to pesticide toxins, with potential benefits for agriculture and human health.
A clinical trial found that financial incentives increased viral suppression among HIV-positive patients, but not linkage to care. The study offered gift cards as incentives and found a 3.8% higher proportion of virally suppressed patients at financial incentive sites compared to standard care sites.
New research suggests that people over-worry about waiting for a 'right time' to enjoy themselves, continually postponing fun. In contrast, studies found that leisure activities tend to be enjoyable regardless of when experienced, with some tasks even enhancing enjoyment when completed before work.
Heterostructural alloys combine materials with different structures to control behavior, providing an additional degree of control. The study focuses on semiconductor applications, creating metastable phases that can be used in solar cells and other devices.
Researchers found that Scots pine benefits from beech presence in forest with high rainfall, while beeches adapt to dry conditions by increasing water efficiency. These findings highlight the importance of considering species complementarity and climate in managing mixed forests.
A new study found that only one in four young adults with opioid use disorder receive life-saving medications for treatment. The study highlights a critical gap in addiction treatment for teens and young adults, emphasizing the need for increased access to effective medication-based care.
A new national poll on healthy aging will release its first results on June 29, tracking key health issues for people between 50 and 80 years old. The poll aims to provide timely insight into current issues affecting older Americans, informing healthcare policy and clinical practice.
Insilico Medicine will showcase its latest AI advancements in aging research and personal health data management. The company aims to apply deep learning to improve biomarker development, predict chronological age, and provide geroprotectors for various diseases.
Researchers at U-M Medical School discovered that a molecule called cathepsin protease L is crucial to the parasite's ability to survive the cyst phase and cause disease. Interfering with this protein can stop the parasite, offering new hope for treatments. The study suggests that targeting the 'stomach' of the parasite may be key to p...
Griffith University researchers used Australia's fastest camera to measure the time it takes for molecules to break apart, achieving a record-breaking 15 millionth of a billionth of a second. This breakthrough could help design new molecules for materials science and drug discovery.
Scientists have found that random diversification and extinction of cells can organize bacteria into taxonomic units as effectively as traditional ecological forces. This discovery challenges current models of microbial classification, highlighting the need for a reevaluation of the task.
Researchers developed a long-term field experiment to monitor post-compaction evolution of soil structure, revealing projected recovery rates of years to decades. Initial results indicate different recovery rates for various properties and decreasing recovery rates with soil depth.
Orly Leiva, a fourth-year medical student at Boston University School of Medicine, has been named to the 2017 Minority Medical Student Award Program. The program supports underrepresented minority students pursuing hematology research projects with $7,000 funding and mentorship.
The HPTN 065 study found that financial incentives can motivate some people living with HIV to take their medication regularly and maintain viral load suppression. This increase in viral suppression was observed at care sites offering financial incentives, with an overall increase of 5% at the peak of the intervention.
A new desalination system uses solar energy to turn salt water into freshwater, promising a cost-effective and sustainable solution for global water scarcity. The technology combines membrane distillation with light-harvesting nanophotonics to efficiently generate steam from sunlight.
The CRISPR-Cpf1 gene editing system has been improved by incorporating a firefly gene, enabling the simultaneous targeting of multiple genes in human cells. This advance could be useful for treating diseases such as hepatitis B and muscular dystrophy.
Scientists used an X-ray free-electron laser to determine the atomic structure of an intact virus particle on a microchip containing thousands of tiny pores. This new method allows for faster and more efficient analysis, reducing sample material waste.
A new study from the Kennedy Krieger Institute found that acupuncture interventions can lead to improved behavior, attention span, sleep quality, and reduced parenting stress in young children with autism spectrum disorder. Most parents reported a positive relationship with their child after participating in the intervention.
Computational biologists discover that protein variations have a significant impact on cell functions, even in healthy individuals. The study's findings could lead to advances in personalized medicine and better understanding of individual responses to environmental influences.
City College of New York scientists discover a rapid method to produce new molecules inhibiting the HIV virus, focusing on modifying nucleosides and their impact on biological activity. The research yields diverse compounds that can be tested for structural effects against the virus.
Berkeley Lab awards $4.6 million for two projects to mitigate risks in California's natural gas system, focusing on risk management and ground deformation monitoring. The projects will help facility operators detect leaks early and prevent catastrophic events.
A new study has classified nearly 3,500 confirmed exoplanets into two distinct size groups: rocky Earth-like planets and larger mini-Neptunes. The researchers used data from NASA's Kepler mission and the W.M. Keck Observatory to make this discovery.
A team from Ireland developed a collagen scaffold loaded with an antibiotic to prevent bacterial biofilm formation, successfully targeting Escherichia coli and Staphylococcus epidermidis. The discovery marks a significant step forward in combating implant infections, which can cause long hospitalization periods and additional surgeries.
Researchers at the University of Illinois used a new technique called eDNA to detect and monitor the Hay's Spring amphipod, an endangered species found in seepage springs in Rock Creek Park. The method successfully detected the creature's DNA in water samples from three sites where it had been previously seen.
Michael Mann, a world leader in climate science, has been awarded the Stephen H. Schneider Award for Outstanding Climate Science Communications. The award recognizes his work on reconstructing global temperature variations over the past two millennia and its significance in understanding human-caused warming.
Researchers have identified the driving force behind differences in sea spray particles' chemical make-up, enabling better understanding of ocean chemistry and physics' influence on cloud formation. The study's findings could improve climate models by providing a more accurate representation of clouds' impact on precipitation.
A team of researchers led by Carnegie Mellon University chemist Roberto R. Gil and Universidade Federal de Pernambuco chemist Armando Navarro-Vázquez has developed a program that automates the process of figuring out a molecule's three-dimensional structure, reducing human error and shortening the pipeline of drug discovery.
MIT biologists identified a mechanism for eliminating genetically imbalanced cells using natural killer cells. Aneuploidy, or uneven chromosome distribution, harms most cells but can help cancer cells grow uncontrollably.
UCSB researchers have developed a method for 3D through-wall imaging using drones and WiFi, enabling objects to be imaged in real-time with high resolution. The technology has potential applications in emergency search-and-rescue, archaeological discovery, and structural monitoring.
Family members of individuals with non-alcoholic fatty liver disease (NAFLD) and cirrhosis are at a significantly higher risk of developing advanced liver fibrosis. A clinical trial found that immediate relatives had 12 times higher prevalence of liver fibrosis than healthy controls, indicating the need for screenings in family members.
A study published in Nature Climate Change warns that 74% of the world's population will face deadly heatwaves by 2100 if current emissions continue. Researchers found a common threshold beyond which temperatures and humidities become lethal, with tropical areas projected to bear the greatest risk.
The TAMEST Shale Task Force report highlights both benefits and consequences of shale development in Texas. Key findings include an increase in earthquakes due to wastewater disposal wells, habitat fragmentation, increased greenhouse gas emissions, and contamination risks to drinking water sources.
Neuroscientists at Johns Hopkins Medicine report that mouse eyes can constrict in response to light without involving the brain. Melanopsin, a light-sensitive pigment, is found in the iris sphincter muscle and causes it to contract.
A study published in the European Heart Journal shows a vaccine that lowers cholesterol may be effective in preventing cardiovascular disease. The AT04A vaccine, administered to genetically modified mice, reduced cholesterol levels by 53% and induced long-lasting antibodies against PCSK9, an enzyme contributing to high cholesterol.
Researchers discovered two ancient fossils from the Triassic Period that connect Kermit the Frog's relatives to wormlike creatures with sharp teeth. These findings expand the history of modern amphibians by 15 million years, closing a major gap in early caecilian evolution.
Researchers found that rhodopsin accelerates visual performance in cold-water catfish at high altitudes, enabling survival. The study provides new insights into the evolution of complex biological processes and potential therapeutic targets for human disease.
A major international study found that some features in a baby's DNA can increase the risk of its mother developing pre-eclampsia. The condition affects up to 5% of pregnancies and can cause serious complications including high blood pressure and organ damage.
Researchers led by SDSU neuroscientist Stephanie Ries discovered that wide swaths of the brain work in parallel to retrieve correct words from memory, challenging previous assumptions about localized language processing. The study's findings could help speech-language pathologists develop strategies for treating disorders like anomia.
Research at the University of Chicago Medical Center identified genetic variations that pre-dispose children to severe forms of neuroblastoma, paving the way for more targeted treatments. Children with MYCN-amplified tumors have a lower survival rate, but understanding their genetic predispositions could lead to more effective therapies.
A recent study by Florida Atlantic University researchers proposes a new capital ratio that would allow regulators to close insolvent banks earlier, potentially saving $18.5 billion in closure costs. The proposed ratio, called the nonperforming asset coverage ratio, could prevent regulators from granting forbearance to insolvent banks.
Researchers at the University of Houston have discovered a new class of material that addresses many battery concerns, including fire risk, cold weather performance, and lifespan. The quinones-based anode is inexpensive, chemically stable, and allows batteries to work across temperature ranges.
A recent study in the Journal of Social and Personal Relationships explores how high levels of relationship anxiety impact partner experiences. Researchers found that individuals experiencing anxiety about their partner's commitment tend to experience increased volatility in their feelings about the relationship.
Researchers at Northwestern University have designed a sugar-coated nanomaterial that promotes bone regeneration by binding to growth factor BMP-2, reducing its need by 100 times. The biodegradable material functions as an artificial extracellular matrix, mimicking natural cell interactions.
Researchers have developed a diagnostic test for amyotrophic lateral sclerosis (ALS) using neurofilaments, which can confirm the presence of the disease. The test has shown promising results in accurately diagnosing ALS patients, with a good correlation between neurofilament levels and motor neuron loss.
Research at Smithsonian Tropical Research Institute found that fig wasps that cheat by not collecting pollen can still flourish in populations where they have a time and energy advantage. This suggests that cheaters may become more common when punishment is too severe, allowing them to reproduce and pass on their non-cooperative behavior.
Researchers at Stockholm University have discovered how bacteria in hot springs control the burning process, providing insights into human cellular metabolism. By studying oxygen combustion at low temperatures, scientists unraveled the mechanism behind the carefully controlled process in our cells.
Rachel Whitaker, Associate Professor of Microbiology at the University of Illinois, receives a $1.5 million award to study mobile genetic elements and their role in microbial evolution. Her research aims to develop a new evolutionary paradigm to combat antimicrobial resistance.
The spruce budworm's massive defoliation can lead to devastating consequences for the forest industry, causing an estimated $3 billion to $4 billion in losses over the next 30 years in New Brunswick alone. Defoliation increases the risk of natural fires igniting eight to 10 years after a budworm outbreak.
A study led by NYU's Steinhardt School found that believing the system is fair predicts lower self-esteem, risky behaviors, and decreased classroom attention in middle school students. This reversal occurs over time as youth become more aware of structural barriers and inequities.
A team of ecologists has introduced five new species of the Syzygium genus, one of the world's largest tree genera, to the island of Sulawesi. The discovery highlights the vast, undocumented plant diversity on the island and raises concerns about the conservation of endemic species.
A team of researchers led by David Julian McClements aims to quantify the ability of food nanoemulsions to increase pesticide bioavailability, posing a risk to human health. The study will investigate how nanoemulsion composition and structure impact pesticide absorption in fruits and vegetables.
The EcoCity model simulates future city expansion and predicts urban heat island effects. The study reveals different surface temperatures in various function zones, with urban impervious surfaces and green spaces playing distinct roles in thermal regulation.
Researchers found clear links between volcanic activity and the end-Triassic mass extinction. The study revealed repeated large emissions of carbon dioxide from volcanoes, which led to a profound impact on the global climate.
A new study found that older adults are less likely to leave the hospital against medical advice than younger individuals, with men and people insured by Medicaid or without health insurance at highest risk. Factors such as race/ethnicity, poverty, and suboptimal communication play a role in this phenomenon.
A recent discovery by Stanford University scientists could lead to a new, more sustainable way to make ethanol without corn or other crops. The technology uses three basic components: water, carbon dioxide and electricity delivered through a copper catalyst.
Researchers found that restoring a healthy balance in gut bacteria can treat Autism Spectrum Disorder (ASD) symptoms. The review highlights several studies showing positive impacts of probiotics, prebiotics, diet changes and faecal matter transplants on ASD symptoms.
Scientists have discovered a new type of immune cell that can predict which lung cancer patients will benefit from immunotherapy treatment. The study found that patients with high levels of tissue-resident memory T-cells in their tumour were more likely to survive, and the cells' behaviour played a key role in increasing survival rates.
Researchers found that increasing roasting levels reduced antioxidant and anti-inflammatory activities in coffee extracts, with chlorogenic acid varying by roast level. The study suggests some beneficial compounds may be affected by the roasting process.
A study analyzing 9.7 million young people found that only 26.8% received medication for opioid use disorder within six months of diagnosis. Younger people, females, and non-Hispanic black and Hispanic youth were less likely to receive medications.
A daily low dose of valnoctamide reduces CMV infection in newborn mice and suppresses replication in the brain, normalizing neurological development. The treatment also attenuates neurobehavioral dysfunctions and brain abnormalities associated with CMV infection.
A developing tropical cyclone in the western Atlantic Ocean is expected to strengthen into a tropical storm within the next five days. NASA provided critical data and cloud height information to forecasters, revealing heavy rain showers and towering thunderstorms with heights above 9.3 miles.
The new biofuel can be used undiluted in modern diesel engines or mixed with petroleum diesel, fulfilling EU and US requirements. It has improved properties compared to traditional biodiesel, which vaporizes at higher temperatures and forms deposits on engine components.
Research by Kevin Langergraber and colleagues reveals that patrolling by male chimpanzees increases group size, leading to increased offspring and long-term benefits. This cooperative behavior outweighs individualized efforts, demonstrating a striking example of group-level cooperation among primates.
A UTEP doctoral candidate has discovered three new species of chameleons in the Albertine Rift region of Central Africa. The reptiles were found to be endemic to specific mountain ranges, with two species named after their habitats and a third species named after herpetologist Krystal Tolley.
Scientists have identified mutations in the CARD11 gene that lead to severe atopic dermatitis, an allergic skin disease. Supplementing with the amino acid glutamine may partially correct the underlying cell-signaling defects, according to a study published in Nature Genetics.
A recent study by Emory University highlights the importance of insecticide-resistance monitoring in controlling the spread of Zika and other mosquito-borne diseases. The research found that applying insecticides like deltamethrin in areas with high resistance can be ineffective, emphasizing the need for targeted control measures.
A study finds that many state pension plans use open-ended amortization to delay payments, making their financial condition appear better than it is. This practice exacerbates funding shortfalls and increases the risk of insufficient funds to pay pension obligations.
Researchers from Nationwide Children's Hospital used a combination of immunotherapies in a mouse model of rhabdomyosarcoma, finding that combining oncolytic virotherapy and PD-1 blockades was more effective than either approach alone. This new strategy marshals more T-cells to attack tumors without increasing regulatory T-cells.
Researchers found that couples who viewed positive images of their spouses paired with cute animals showed improved marriage quality. The intervention used evaluative conditioning to create automatic associations between the spouse's face and positive feelings.
Researchers at La Jolla Institute for Allergy and Immunology identify tissue-resident memory T cells as an important distinguishing factor between cancer patients whose immune system mounts an effective anti-tumor response. The study found that patients with a high density of these cells in tumor tissue survived significantly longer.
The study highlights potential widespread presence of mosquitoes Aedes aegypti and Aedes albopictus in the US, as well as gaps in local surveillance capabilities. This information will help target limited public health resources and improve understanding of these mosquito species' distribution.
Experts conclude that a near-zero-emissions energy system will require a diverse portfolio of energy technologies, including bioenergy, nuclear energy, and carbon capture technology. The study corrects previous research suggesting the US can be powered solely by solar, wind, and hydroelectric energy.
A University of Alberta research team found that patients with obesity have a higher risk of infection within 30 days after heart bypass surgery, and 88% of these patients received non-surgical PCI. This increased risk may be due to the fact that patients with obesity are more likely to receive PCI.
The Gauss Centre for Supercomputing (GCS) has secured €500 million in funding for the next decade to invest in next-generation systems and strengthen comprehensive user support. The organisation aims to deliver world-class supercomputing resources while fostering interdisciplinary collaboration between researchers and industry.
Scientists used CRISPR/Cas9 gene editing to reverse Huntington's disease pathology and motor symptoms in a mouse model. The treatment delivered enzymes to brain cells, reducing toxic protein aggregates and improving motor abilities.
A recent study by Columbia University found that financial incentives significantly increased viral suppression and clinic attendance among HIV-positive patients. The study showed a four-percent higher percentage of patients with suppressed virus at sites offering gift cards compared to those without.
A phase 1 randomized controlled trial found an Ebola virus disease vaccine developed in Canada to be well-tolerated and effective, with high antibodies present six months after immunization. The vaccine showed no safety concerns and was well-received by participants.
A study found that 9 out of 10 A🌳 departments fail to identify young people with alcohol problems, preventing vital help. Over 85% of departments do not routinely ask young people or those over 65 about their drinking habits, despite NICE guidelines recommending screening and feedback.
A new study reveals that rising CO2 levels reached a tipping point, triggering sudden temperature shifts of up to 15°C in the Northern Hemisphere during ice age periods. The findings add to evidence suggesting that gradual climate changes can lead to abrupt surprises.
A Drexel University study reveals that birds of different species cooperate to access food sources by following army ant marches. Facilitation theory supports this behavior, where species help each other exploit shared resources.
UW researchers design polymers that can effectively communicate across biological and electronic realms by creating rigid and non-rigid regions with varying conductance properties. These findings may lead to new biosensors, flexible bioelectronic implants, and improved batteries.
Researchers are studying the clinical outcomes of children infected with Zika virus after birth to examine long-term brain development. Neurodevelopmental testing will be conducted to identify changes in children infected with Zika virus.
A systematic review reveals widespread self-medication misuse in the Middle East, with pharmacies selling up to 97% of antibiotics without a prescription. The study emphasizes the need for improved policies and education to address this issue.