A recent study found that a significant number of older adults with delirium were not diagnosed by healthcare professionals. The researchers concluded that developing more objective screening tools could improve diagnosis accuracy. Understanding delirium is crucial to recognize and address the condition in older adults and caregivers.
Researchers studied data from nearly 4 million Medicare beneficiaries over 65 with multiple chronic conditions, comparing hospitalizations, deaths, and medical costs between those who saw PCPs and specialists. People who saw PCPs had fewer hospitalizations and lower costs.
Scientists developed an algorithm to accurately identify multiple signals at multiple levels in the circuit to detect open-switch faults. The combination of the algorithm and artificial neural network can improve microgrid reliability, efficiency, and cost.
Researchers from AWI demonstrated how the Arctic Ocean transformed into a saline body after the land bridge between Greenland and Scotland submerged, enabling Atlantic circulation. The study found that changes occurred when the ocean passage reached a depth of over 50 meters below the surface mixed layer.
Researchers found that capecitabine results in fewer side effects and improved quality of life, while being as effective as CMF in preventing breast cancer recurrence. Over 85% of patients did not experience their cancer returning for at least five years.
A new electronic sepsis alert protocol has been implemented in pediatric emergency departments, reducing missed diagnoses of severe sepsis by 76 percent. The protocol uses a combination of vital signs, risk factors, and physician judgment to identify children at high risk of developing sepsis.
Recent clinical trials using different gene transfer approaches have shown acceptable risk and potential for treating heart failure with reduced ejection fraction. Despite mixed results in terms of efficacy, the data support further clinical development of this therapeutic strategy.
Researchers at KAUST developed a novel catalyst to split water efficiently in acidic conditions, paving the way for greener power sources. The molybdenum coating improves stability and prevents oxygen recombination, enabling longer-term hydrogen production.
Implementation of community-based testing and treatment programs was associated with increased HIV diagnosis, ART initiation, and viral suppression among HIV-positive adults. After two years, 80% of residents achieved viral suppression, and 96% had been previously diagnosed.
A new study by UW-Madison undergraduate Ben Hoscheit confirms the idea that our galaxy lives in an enormous void, seven times larger than average. The findings help ease tension between different measurements of the Hubble Constant, resolving a long-standing discrepancy among cosmologists.
Researchers found that insomnia is three times more likely to report thoughts of suicide and death among U.S. Army servicemembers compared to those without the condition. Insomnia was a significant predictor for suicidality, with wakefulness at night associated with increased suicidal ideation.
A study published in eLife discovered that loss of muscle stem cells is the main driving force behind muscle decline in old age in mice. By depleting muscle stem cells, researchers found that muscle decline accelerated, while mice with preserved stem cells maintained healthier muscles at older ages.
Advances in lab-on-a-chip technology allow for more accurate analysis and translation of research to the clinic. Organ-on-a-chip (OOAC) technology has great potential in helping screen drugs in a more cost-effective manner, reducing failures and costs.
Researchers have developed a novel approach to detecting dengue infection using PET-FDG imaging, which tracks glucose uptake and predicts disease progression. This non-invasive method has the potential to transform the assessment of new treatments in clinical trials.
Scientists at Gladstone Institutes discover distinct neurons in the reticular thalamus, a region involved in attention, perception, and consciousness. The study reveals that targeting specific cell types can disrupt seizures or affect cognition and emotion.
Researchers have discovered a new complex of enzymes in herbivore gut fungi that can break down plant biomass into sugars, offering potential for sustainable fuels and chemicals. The unique structure of these enzymes, called cellulosomes, has the potential to be engineered for industrial use, reducing the need for current enzyme mixtures.
A new study found that frequent coffee consumption was significantly associated with lower odds of high liver stiffness values, independent of lifestyle traits. Herbal tea consumption also showed a significant association with lower liver stiffness values, even in small amounts.
Researchers at the American Society of Hematology report on the effectiveness of enasidenib in treating a rare form of leukemia. Enasidenib demonstrates significant benefits as a targeted treatment for this aggressive disease, offering new hope for patients with limited options.
A computational model of the soybean plasma membrane reveals that similar lipids cluster together due to van der Waals interactions. The research has applications for studying membrane proteins and understanding plant responses to stressful conditions.
Researchers from Florida Atlantic University caution that copaiba's potential benefits for treating inflammatory arthritis are unproven due to limited evidence. Despite this, sales of the essential oil continue to increase, presenting clinical challenges.
A study published in the Journal of the American College of Surgeons found that trauma centers verified by the American College of Surgeons Committee on Trauma have lower complication rates for pediatric and elderly patients. The study analyzed data from the National Trauma Data Bank and found that patients treated at non-verified trau...
Researchers at the University of Copenhagen have developed a model to control alcohol content in liquid dishes, including red wine sauces. By adjusting cooking time and technique, cooks can reduce alcohol levels, making it safer for pregnant individuals or those tracking calories.
A University of Zurich study analyzed archived tissues from dog mammary tumors to understand breast carcinoma in both species. The researchers found that tumor cells reprogram healthy cells, promoting tumor growth, a mechanism also observed in human breast carcinoma.
Researchers at the University of Texas at Austin identified several plant-based compounds that can prevent or slow down prostate cancer growth. The study found that combining these compounds, such as ursolic acid and curcumin, with glutamine can block the nutrient uptake needed by prostate cancer cells.
A new assay developed by University of Illinois researchers can identify Palmer amaranth DNA in mixed seed samples, overcoming slow and unreliable testing methods. The low-cost technique uses quantitative PCR to detect genetic variations unique to Palmer, enabling farmers to certify their product as Palmer-free.
Professor Coaldrake was recognised for his role in helping turn Brisbane into an international creative hub for education, innovation and knowledge. He has overseen the development of QUT's Learning Potential Fund, which provides scholarships and bursaries for students from low SES backgrounds.
Astronomers have captured unique close-up views of the universe's brightest infrared galaxies, which are as much as 10,000 times more luminous than our Milky Way. The galaxies' star-birth production is 5,000 to 10,000 times higher than that of our Milky Way.
KELT-9b, a Jupiter-like gas giant, has a 'year' of only 1.5 days and orbits an extremely hot star that radiates more ultraviolet radiation than our sun. The planet's atmosphere is constantly blasted with high levels of radiation, making it inhospitable to life.
Researchers at Brigham and Women's Hospital have developed a new model to mimic the blood-brain barrier, using miniature spheroids that replicate key properties and functions. This innovative approach may advance neuroscience research and expedite the discovery of brain-penetrant drugs for treating diseases.
Research by University of Exeter scientists shows motorboat noise reduces fish survival rates and changes parental behavior, with increased aggression and reduced feeding among affected males. Motorboat noise is considered a global pollutant, distracting fish from protecting their young.
Researchers developed a stem cell-based therapy to generate skin grafts for myelomeningocele defects before birth. The treatment successfully covered large defects and protected the spinal cord, but had some drawbacks, including decreased birth weight and body length.
A study of over 1,800 patients found that tildrakizumab significantly improved skin conditions in those with moderate-to-severe psoriasis. The treatment demonstrated a 75% improvement in PASI scores at 12 weeks, with fewer than 10% of placebo recipients showing similar results.
Researchers at EPFL developed a dynamic test method that replicates blood and lymphatic systems, allowing for more accurate nanoparticle testing. This method reduces discrepancies between in vitro and in vivo tests, providing valuable insights into nanoparticle behavior.
A recent study found that even moderate drinking is associated with an increased risk of adverse brain outcomes and steeper decline in cognitive skills. Higher alcohol consumption over 30 years was linked to hippocampal atrophy, poorer white matter integrity, and faster decline in language fluency.
A national fruit and vegetable subsidy is estimated to avert 150,500 CVD deaths, while a mass media campaign might reduce deaths by 25,800. A tax on sugar sweetened beverages could avert 31,000 CVD deaths, with a combination of these policies potentially saving around 230,000 lives
Researchers found that variable advisory speed limit systems can decrease average queue length by 39-53% and increase safety with a 30% drop in rear-end collisions, while also reducing maximum speed differences and lane changing conflicts.
Researchers from NC State University developed an ultra-thin sound diffuser that is 10 times thinner than existing designs, reducing echoes and improving sound quality. The new design uses less material and takes up less space, making it lighter and less expensive.
A nationwide team of security experts, led by Clemson University's Hongxin Hu, is developing a new operating system to fundamentally change how large computer and network systems are built, making data more secure. The S2OS system could be transformative for cloud computing, protecting users' data from cyber threats.
A systematic review and meta-analysis found that women who gained more than the recommended weight during pregnancy were at a higher risk of small for gestational age, preterm birth, and cesarean delivery. In contrast, those who gained less than the recommended weight had a lower risk of large for gestational age and macrosomia.
A new molecular modeling method using freely available software provides accurate predictions of solubility. The approach exploits thermodynamic expressions and can be applied to any solute-solvent combination, making it a crucial tool for industries such as pharmaceuticals and petroleum.
Researchers at Johns Hopkins University found that the Lombard effect, a phenomenon where animals raise their voices to be heard over noise, occurs in just 30 milliseconds, making it a fundamental temporal reflex. This discovery sheds light on human speech control and reveals a shared auditory process among species.
Three EU-funded projects synthesize research knowledge on high-end climate change impacts and adaptation for key policy sectors. Research highlights potential risks, challenges, and opportunities for transformational change, including innovative solutions for coastal zone adaptation.
Dr. Nancy Chiaravalloti was awarded the 2017 Mitchell Rosenthal Memorial lecturer for her contributions to cognitive rehabilitation research and successful mentorship of postdoctoral fellows.
A study published in PLOS Biology found that duration, biomechanics, and force influence the subjective effort associated with arm movements, while movement amplitudes have no effect. The researchers also discovered a link between brain functions involved in decision-making and movement execution.
Researchers found that gut bacteria can limit Listeria growth and prevent infection in immunocompromised mice. Probiotic bacteria species were identified as protective against Listeria infections in laboratory cultures.
Researchers at Salk Institute developed a new protocol to derive astrocytes from human stem cells, which could provide breakthroughs for treatments of stroke, Alzheimer's and psychiatric disorders. The method allows for faster and more effective production of astrocytes, enabling researchers to model neurological disorders in a dish.
The Gerontological Society of America and New America Media have selected 18 journalists to participate in the Journalists in Aging Fellows Program. The fellows will focus on producing in-depth stories on aging issues such as disparities in hospice access, mental health treatment for African Americans, and isolation of older adults in ...
A new study suggests that dronabinol, an old pharmaceutical product, could be a potential treatment for obstructive sleep apnea. Researchers found that the drug reduced the frequency of apneas and hypopneas during sleep, decreased subjective sleepiness, and improved overall treatment satisfaction.
Researchers study how baleen whales use crossflow filtration to separate prey from water without contact, shedding light on whale evolution and conservation. The study finds that larger body size enhances this form of filtration, affecting a whale's drag and energy needs.
A new study by the American Academy of Sleep Medicine found that sleep disturbances are strongly related to substance use among college athletes. Student athletes with sleep difficulties were more likely to smoke, drink, and use illegal substances, including a 317% increase in methamphetamine use.
Researchers propose pairing remote wind farms with conventional units to reduce power storage needs, improving reliability. The approach uses an algorithm to estimate future wind states and provides limitations for extreme wind states.
A new study uses a novel chemical technique to assess the impact of human activity on coral skeletons, revealing devastating effects of pollution and climate change. The research provides critical information for predicting future reef health and informs mitigation strategies for tropical islands facing similar challenges.
Researchers from the University of Oldenburg and Alfred Wegener Institute found that competition within the krill population drives fluctuation cycles. The study suggests a self-generating mechanism in the population is responsible for the variability.
Researchers found that vaccinated obese adults are twice as likely to develop influenza and flu-like illnesses compared to those of healthy weight. The study suggests that existing blood tests may provide misleading information for obese individuals.
Early research suggests that immunotherapy may provide new hope to patients with relapsed mesothelioma. A phase II clinical trial found that the combination of nivolumab and ipilimumab slowed cancer growth by 44% and tumor shrinkage in 26% of patients.
Researchers found that babies who shared a room with parents after the first four months had poorer sleep quality and more unsafe sleeping practices. The study suggests that the American Academy of Pediatrics should reconsider its recommendation to room-share for the entire first year.
A study found that only 9% of patients with Acute Myeloid Leukemia (AML) received the recommended seven genetic tests, highlighting a significant gap in adherence to guidelines. The CONNECT registry data also showed varying rates of compliance among different patient groups, including age and insurance status.
The American Association for Cancer Research has published its first set of consensus screening recommendations for children with common cancer predisposition syndromes. The guidelines provide standardized approaches to surveillance and facilitate appropriate monitoring of children affected by these conditions.
Engineer Dr. Joseph S. Friedman designs a novel computing system made solely from carbon that might replace silicon transistors in electronics. The resulting all-carbon spin logic proposal enables cascaded logic gates with increased performance and potential terahertz clock speeds.
A new study found that generous health insurance plans with low deductibles and copays can lead to unnecessary treatments for chronically ill patients. The study suggests that personalized medicine interventions, providing more information about treatment effectiveness, can reduce healthcare costs and improve patient outcomes.