Researchers found that platelets release TGF-beta to suppress T cells and promote immune tolerance to certain cancers. Adding antiplatelet drugs like aspirin may improve adoptive T cell therapy against melanoma and other cancers.
Researchers used underwater microphones to detect and map harbor porpoise habits in the Maryland Wind Energy Area. They found that porpoises occur significantly more frequently during January to May and forage for food in the evenings.
Wei Chen, a UTA physics professor, has received the Best Paper Award from American Scientific Publishers for his pioneering work on using nanoparticles to treat cancer. His research involves activating toxins to kill cancer cells and has led to over 20 further journal articles and international recognition.
Scientists at McGill University propose a new theory on how Earth's crust was created, suggesting that silica-rich minerals condensed and fell back to earth over about a million years. This process, called aerial metasomatism, could provide clues for the search for life on exoplanets.
Dendritic cells are crucial for immunity against pathogens and foreign substances. Researchers found that these cells develop from specialized progenitors, not a common progenitor, providing insights into the regulation of human immune responses.
Researchers have identified DNA polymorphisms causing two knockdown resistance mutations in the pyrethroid and DDT target site gene of Phlebotomus argentipes sandfly. These mutations, similar to those found in mosquitoes, are linked with insecticide resistance and pose a significant threat to Leishmaniasis control.
A new study found that simple calf muscle stretching can improve blood flow and reduce leg pain in people with peripheral artery disease. After four weeks of daily stretches, participants were able to walk half a city block farther and their leg discomfort was prolonged.
Researchers find that parts of Antarctica's ice sheet have remained stable for millions of years, despite recent warming. The discovery helps scientists refine predictions of the region's response to climate change and potential contribution to sea level rise.
Tropical Cyclone Donna was a Category 2 hurricane that blanketed the islands of Vanuatu with strong storms and heavy rain potential. The storm's cloud top temperatures were as cold as minus 63 degrees Fahrenheit, indicating heavy rainfall.
A new study reveals pregnant women are nearly twice as likely to experience a traumatic injury resulting from violent assault and die from their injuries compared to non-pregnant women. The research highlights the need for universal screening in Ob/Gyn clinics.
Research by the German Cancer Research Center found that vitamin A deficiency can lead to a loss of dormant stem cells in the bone marrow, impairing the immune system. The study suggests that understanding how vitamin A regulates these stem cells could lead to new cancer treatments.
A research team identified a mechanism by which influenza A viruses hijack cellular machinery to replicate, including the RNA exosome. This process is linked to congenital defects and neurodegeneration in people with rare mutations. The study offers future insight into common brain disorders such as Alzheimer's and Parkinson's diseases.
A five-year national study found that regions with stronger gun laws had significantly fewer firearm-related pediatric emergency department visits. The study suggests an association between regional gun laws and firearm-related injuries in children, with stricter laws linked to lower incidence rates.
Researchers at UT Health San Antonio have developed a gene-transfer technique that increases insulin-producing cells, potentially curing Type 1 and improving Type 2 diabetes. The therapy has cured diabetes in mice without side effects, offering a major advance over traditional insulin therapy.
A study found that retirement lowers biological stress levels in higher-status jobs, but increases them in lower-status jobs. This widening of the socio-economic-health gradient could contribute to rising health inequalities in old age.
Researchers have identified three additional compounds in chicken livers treated with Roxarsone, a common poultry feed supplement containing arsenic. These methylated compounds are up to 30,000 times more toxic than Rox and may pose significant risks to human health if consumed.
New research contradicts previous study suggesting East Antarctic Ice Sheet gains mass, instead shows significant losses. The findings indicate Antarctica as a whole contributes to sea level rise, with the East Antarctic Ice Sheet playing a more limited role.
Researchers at the University of Sussex have developed a shape-changing fog screen called MistForm, allowing users to interact with 2D and 3D objects in mid-air. The display optimizes visibility and facilitates interaction, adapting to single or multiple users.
Children with MRSA bacteremia have a low mortality rate of 2%, but experience high complication rates that increase with each passing day. The risk of treatment failure is associated with infections in muscles, bones, or blood vessels, and concurrent critical illnesses, highlighting the need for optimized vancomycin dosing and monitoring.
Joseph Park, a second-year student at Boston University School of Medicine, has been awarded his third Howard Hughes Medical Institute's (HHMI) Medical Research Fellowship. He will delve into the cell biology of chlamydia to advance knowledge of the disease and become a physician-scientist.
Researchers have developed a new model to predict the extinction of alpine plants, finding that populations are not adapting quickly enough to climate change. The study shows that even favorable climate scenarios can lead to population decline if warming continues without restraint.
Researchers at the University of Pennsylvania School of Medicine found that obese women are less than half as likely to experience strokes, seizures, and other serious complications of preeclampsia. The studies also identified risk factors for persistent high blood pressure after delivery among women with preeclampsia.
Researchers found that viewers make comparisons between characters to judge their morality, with heroes appearing after villains making them seem more heroic. The study suggests that perceived villainy comes with certain advantages, such as increased altruism, in fictional narratives.
A new study analyzed 21,380 nephrectomies and found the 30-day mortality rate to be only 0.5%. Established risk factors were confirmed, with old age, co-morbidities, significant blood loss, and advanced stage of disease identified as major contributors.
Researchers at the University of Pennsylvania School of Medicine found that obese women are less likely to experience severe complications from preeclampsia, such as stroke and seizures. The studies also identified risk factors for persistent high blood pressure after delivery among women with preeclampsia.
Research on fruit flies reveals that those lacking the Fragile X protein have less inhibition among their neurons, resulting in impaired information processing and increased anxiety. This finding provides valuable insights into human brain diseases and may lead to new treatments for Fragile X syndrome.
A new mutation in the Lotus japonicus plant has been identified, resulting in leaves with white spots. The mutation is linked to a shortage of chloroplast proteins, which are crucial for plant growth, and may hold clues for improving ornamental plants.
A recent study by NYU and the Visiting Nurse Service of New York found that only 18.1% of RN visits and 26.7% of PT visits with LEP patients were language concordant, pointing to a lack of understanding of the language capacity of the US healthcare workforce. This highlights the need for more research on this subject and the implementa...
A study published at the 2017 Pediatric Academic Societies Meeting found that children's hospital admissions for suicidal thoughts or self-harm more than doubled between 2008 and 2015, with significant increases in all age groups. The study also identified seasonal variations in cases, with most occurring during spring and fall.
The RICMAC trial found that dose-reduced conditioning followed by allogeneic stem cell transplantation improved overall and relapse-free survival for patients with myelodysplastic syndrome. Engraftment rates were comparable between the two groups, with higher non-relapse mortality after standard conditioning.
A recent study has identified genetic mutations in 14 genes as the primary cause of childhood overgrowth syndromes, which are characterized by excessive growth and intellectual disability. The researchers found that these genes play a crucial role in epigenetic regulation, controlling how and when other genes are expressed.
Researchers at the University of Pittsburgh's Swanson School of Engineering have found that graphane could transport protons without water, potentially leading to more efficient hydrogen fuel cells. The unusual properties of graphane enable it to rapidly conduct protons across a membrane, making it suitable for anhydrous conditions.
Researchers argue that current measurements like global warming potential mask the effects of greenhouse gases over different timescales. A new approach recognizing both 20- and 100-year time scales could provide clarity to climate change policy analyses and avoid misleading debates.
Researchers developed a new process to create graphene from ethene, using higher temperatures than previous methods. The technique could open up new applications for graphene due to its lower cost and simplicity.
A new study found that a TB vaccine candidate is safe and effective in adolescents infected with Schistosoma mansoni, a parasitic worm. No serious adverse events were recorded during the trial.
A new analysis reveals heart failure patients experience worse survival rates than prostate cancer and breast cancer survivors, but better outcomes compared to lung cancer and ovarian cancer. The study highlights the continued burden of heart failure as a major public health concern.
A 250-kilometer-diameter basin in the Falkland Islands exhibits traits of a large impact crater, including decreased gravity strength and increased magnetic field strength. The structure is estimated to be approximately 270-250 million years old, potentially correlating with the largest mass extinction event.
A team of researchers from UNIST and Korea University has developed a self-sustaining sensor platform to monitor water motion dynamics, frequency, and amplitude. The platform harnesses energy from water motion to perform multiple functions simultaneously, enabling continuous monitoring without external power source.
Researchers propose a novel approach to treating newborns with opioid exposure based on their ability to eat, sleep, and be consoled. This alternative method significantly reduces the length of hospitalization without increasing readmission rates.
A new study examines 'small for gestational age' (SGA) across Europe and finds that birthweight has a strong impact on reference percentiles for very preterm infants. Country-specific references are recommended to effectively benchmark outcomes for SGA in each population.
Researchers have identified a group of critical cells in the testes that play a key role in repairing damage to produce healthy sperm. These Miwi2-expressing cells are essential for regeneration and may help preserve fertility in pre-pubescent boys undergoing cancer treatment.
Replacing beef with insect-based foods could reduce greenhouse gas emissions and free up vast areas of land, according to a new study. The researchers found that eating more insects or imitation meat could halve global consumption of animal products, freeing up 1680 million hectares of land.
A new study found that lead exposure has a negative impact on cognitive and language development in preschoolers, with poverty amplifying these effects. The research analyzed data from the Bellevue Early Language and Education Project and showed that even low levels of blood lead above 5 micrograms per deciliter can cause reduced cogni...
Researchers developed polypeptide catalysts that function efficiently in water, which could reduce the use of organic solvents and toxic waste in chemical processes. The discovery has potential applications in pharmaceutical, agrochemical, and food industries.
Research suggests a simple saliva test can predict which children will experience prolonged concussion symptoms, providing a more accurate prognosis than standard survey questions. The study found that salivary miRNA levels were significantly more effective in predicting prolonged concussion symptoms than SCAT-3 surveys.
Scientists successfully completed the first EPA-approved outdoor field trial for genetically engineered algae, testing a strain in real-world conditions without adverse impact on native populations. The study demonstrates the feasibility of cultivating genetically engineered algae outdoors while maintaining engineered traits.
The Entomological Society of America has published a comprehensive review on identifying, biology, impacts, and management of various stink bug species affecting Midwestern corn and soybean growers. The guide provides methods for differentiating species, life cycle summaries, and guidance on monitoring and managing pests.
Researchers found that white blood cell counts at baseline and during therapy predict whether patients will respond to nivolumab treatment. A greater number and concentration of natural killer cells were associated with response to treatment.
Research suggests that exosomes derived from very obese patients' fat can accelerate biological processes leading to atherosclerosis. In contrast, those from lean patients promote cholesterol efflux and reduce 'bad' cholesterol buildup. This discovery holds promise for early detection of chronic diseases in children.
Researchers developed a technique using multimodal autofluorescence and light scattering to evaluate kidney function after ischemic injury. The study suggests that variations in tissue microstructure, fluorophore emission, and blood absorption spectral characteristics contribute to the behavior of recorded signals.
Researchers found that infants taking antacids had a higher risk of fractures during childhood, especially those who started treatment under 6 months old. The study suggests that antacid medications should only be used for severe symptomatic gastroesophageal reflux disease in young children.
NCAR will develop a three-year project to provide detailed forecasts of wind and solar irradiance at Kuwait's 2-gigawatt Shagaya renewable energy plant. This technology will help Kuwait reach its goal of generating 15% of its energy from renewable sources by 2030.
Researchers have developed a new class of CRISPR enzymes that can detect specific sequences of RNA, including those from viruses. These enzymes, variants of Cas13a, target different RNA nucleotides, allowing for simultaneous viral diagnostics and potentially expanding the range of diseases they can detect.
A recent study identified around 6,500 human genes that are expressed differently in men and women, with some genes playing a crucial role in body hair growth, muscle building, and fat storage. The research suggests that natural selection puts less pressure on genes specific to one sex or the other.
The Teaching Health Centers (THC) program, created under the Affordable Care Act, funds 700 primary care residents to serve in 28 states, helping 500,000 people living below poverty line, most with public insurance or none.
Moleculomics' new technology accelerates drug discovery by simulating protein interactions with chemicals, reducing development time and cost. The platform enables the high-throughput screening of candidate compounds against human proteins, identifying safe and toxic compounds.
Glicksberg's study found that specimen pH, temperature and chemical structure had a significant influence on drug stability. Her research may help predict the stability of future synthetic cathinones.
Researchers at the Institute of Physical Chemistry of Poland have demonstrated that increasing light intensity can accelerate chemical reactions by several dozen percent. This discovery has implications for various applications, including microscopic imaging techniques and ultra-fast spectroscopy.
Chronic fluid overload increases the risk of early death in kidney failure patients on hemodialysis, comparable to coronary artery disease and heart failure. The study found that cumulative exposure to fluid overload over 1 year predicted a higher risk of death than a single measurement at the start of dialysis treatment.
Researchers found reduced proliferation capacity and increased rates of cell death in MSCs from patients with acute myeloid leukemia at diagnosis. These alterations may play a role in the development of leukemia, according to the study published in Stem Cells and Development.