Bacteria resistant to ampicillin emerged several years before its widespread use in humans, according to a new study published in The Lancet Infectious Diseases. Low doses of penicillin added to animal feed in the 1950s and 60s may have encouraged antibiotic-resistant bacteria to evolve and spread.
A home-based activity program called Tailored Activity Program (TAP) was found to significantly reduce dementia-related behaviors in veterans, as well as decrease caregiver distress. After four months, nearly 70% of TAP group participants eliminated or reduced their behavioral symptoms compared to 46% in the control group.
A recent study published in Psychological Science found that employees whose personality traits closely match their job requirements tend to earn more than those who don't. The researchers used response surface analysis to create a model that identified the relationship between personality traits, job demands, and income.
Researchers highlight the challenges of preparing seasonal influenza vaccines in eggs, citing reduced effectiveness rates of 40-60 percent. They also emphasize the need for targeted research on manufacturing strategies and vaccine antigens to improve vaccine efficacy.
A new image-guided pulsed radiofrequency treatment has shown extraordinary results in relieving low back pain and sciatica. The procedure involves inserting a probe to deliver energy to the affected area, resolving herniation without thermal damage, and patients were largely pain-free within a day.
Researchers found that antibiotic-resistant bacteria evolved and spread decades before the widespread use of ampicillin. The study suggests that low doses of penicillin fed to livestock may have triggered this evolution.
A new study published in Endangered Species Research found that chronically entangled North Atlantic right whales have high hormone levels indicating severe stress. The research used fecal samples from live, entangled, and dead whales to investigate stress levels and determine cause of death.
A UCL-led study found that inhibiting RNA polymerase III, a common enzyme in all animals, extends the lifespans of yeast cells and animals by an average of 10%. This discovery may lead to targeted anti-aging therapies, similar to the effects of rapamycin.
A new study reveals prehistoric women had up to 30% stronger arm bones than modern rowers due to activities like grinding grain and performing manual labor. The research suggests that the varied work of early agricultural women played a crucial role in shaping their physical strength.
The Heilbrunn Department at Columbia University is conducting a study to measure the impact of the expanded Mexico City Policy on women's health and wellbeing in Kenya and Nepal. The research aims to assess the current policy's effects on access to life-saving services such as abortion, contraception, and HIV testing and treatment.
Researchers at George Mason University are developing new techniques for photo editing using machine-learning algorithms, allowing for easier material changes. They are also working to improve streaming video quality on mobile phones by utilizing the features of HTTP/2.
The NIH has awarded the Center for BrainHealth $2.5 million to examine cannabis use disorders and understand brain mechanisms behind problems related to cannabis use. The study aims to identify individual and cultural effects on severity of cannabis use disorder and inform public health policies.
Scientists at Max Planck Institute discovered robust Bain distortion in premartensite phase of Pt-substituted Ni2MnGa, which transforms to martensite with additional Bain distortion on further cooling. This phenomenon enhances applicability as magnetic actuators and refrigeration technology due to lower hysteresis.
Experts at the Global Innovation Summit propose 10 guiding principles for sustainable economies, emphasizing research, education, and responsible resource development. The summit highlights innovative technologies like AI, sensors, and additive manufacturing to drive efficient production and mitigate environmental challenges.
Researchers developed a synthetic cannabis-like drug that was safe and effective in treating obstructive sleep apnea. Participants in the trial had reduced apnea and decreased subjective sleepiness after taking the drug for six weeks.
The LigniOx project aims to commercialize a lignin-based concrete plasticizer technology that can compete with synthetic admixtures. The technology has shown promising results in enhancing workability and strength of fresh and matured concrete.
Researchers at the German Cancer Research Center found that natural infection with malaria induces a strong immune response, producing antibodies that protect mice from infection. The study's findings will help develop more effective and specific vaccines against the disease.
New research from UC Davis Health finds that denying patient requests for specialist referrals, laboratory tests, or medications leads to lower clinician satisfaction ratings. Communications training is recommended to help doctors effectively manage patient requests and balance patient needs with resource efficiency.
The study found that trisomy 21 affects proteins on all chromosomes, leading to an overdose of proteins and dysregulated cellular functions. This deregulation disrupts the cell's ability to regulate protein production, resulting in symptoms such as intellectual impairment and congenital heart disease.
Researchers found that dogs exhibit mouth-licking behavior in response to visually perceived anger, suggesting a form of communication with humans. The study suggests that domestication may have selected this behavioral trait, indicating dogs' potential understanding of emotional information.
A new study suggests that combining Virtual Reality and treadmill exercise therapy can dramatically lower the incidence of falling among Parkinson's patients. The therapy promotes beneficial brain plasticity, even in patients with neurodegenerative disease, and enhances motor control and cognitive performance.
Researchers developed a new method to protect quantum information in trapped ions by leveraging dissipation. The approach allows for autonomous correction of quantum states without requiring logical circuits or measurements.
Amanda Botticello at Kessler Foundation leads a study on a six-week cognitive-behavioral intervention to enhance self-efficacy and community participation in individuals with spinal cord injuries. The five-year grant aims to enroll over 250 participants and improve outcomes for people with SCI.
A review paper compares health determinants of people and healthcare systems in Thailand, Lao PDR, Vietnam, and Cambodia. The study highlights the need for policies impacting population health and country development to guide policymakers and healthcare providers.
A new study at Boston Medical Center will test Gabby's effectiveness in reducing pregnancy health risks. The AI-powered system has been successful in previous trials, identifying and resolving health risks by over 25% compared to a control group.
A new project at Lancaster University aims to discover the likely privacy and security challenges arising from children using IoT devices. Researchers will work closely with child protection experts to provide guidelines and advice for children, their families, and teachers on programming IoT devices.
Researchers developed a novel method called CRISPR-AID that combines genetic manipulations to improve metabolic engineering efficiency. By exploring different combinations of gene modifications, scientists can discover optimal solutions for specific goals.
Researchers have identified lymphocyte clusters in the pericardial adipose tissue as key regulators of the post-infarction immune response. These clusters stimulate an immune reaction that degrades damaged tissues, but also promote tissue repair. The findings suggest a critical role for this process in heart healing.
The Biogerontology Research Foundation's Managing Trustee, Dmitry Kaminskiy, will present on the synergistic convergence of AI and Blockchain in healthcare. The conference aims to transform clinical translation and validation of therapies aiming to extend healthy, productive longevity.
Studies show that spelling problems in dyslexic children can modify or impair their writing skills. Researchers analyzed the relationship between learning to spell and physical writing processes, finding that spelling difficulties significantly affected handwriting.
The OPTIMISTIC program reduced avoidable hospitalizations among long-stay nursing facility residents by 33%, eliminating nearly one in five hospitalizations. The initiative lowered Medicare expenditures by $1589 per resident, resulting in a total savings of over $13.5 million from 2014 to 2016.
Researchers identified specific gene expression patterns in women who appear younger than their chronologic age, suggesting that genetic changes may slow down skin aging. The study revealed accelerated changes in pathways related to oxidative stress, energy metabolism, and senescence with increasing age.
Researchers at University of Toronto and Istanbul Technical University propose an 'active drip' model for the formation of the Central Anatolian Plateau, where the lower tectonic plate has dripped below Earth's surface. This process is linked to the planet's crust and upper mantle thickening and sinking into the lower mantle.
A new study using pluripotent stem cell technology reveals that having too much or too little of the CHRNA7 gene can lead to similar biological effects in brain cells. This discovery sheds light on the mechanisms underlying neuropsychiatric disorders and offers a potential avenue for treatment.
Researchers from UNIGE have identified a key role for the liver in the development of type 2 diabetes, linked to obesity and inflammation. By targeting the protein PTPR-γ, scientists may uncover new therapeutic strategies to prevent insulin resistance and related metabolic conditions.
Research reveals that online products sold as selective androgen receptor modulators (SARMs) may contain unapproved substances or incorrect amounts. Most products did not match label information, highlighting the need for greater regulatory oversight of these appearance- and performance-enhancing drugs.
A new report by ECDC and WHO reveals that over half of HIV diagnoses in Europe occur at a late stage, leading to poorer health outcomes and increased transmission risks. Early diagnosis is crucial to prevent these outcomes, with improved testing practices and community-based services vital to addressing the issue.
The team is developing a new technique to use human actor movements to drive four-legged animal characters, making animations more realistic. The project involves collecting motion capture data from various dog breeds at the Bath Cats and Dogs Home.
A team of researchers has demonstrated a simple approach for coupling solution-synthesized cesium lead tribromide (CsPbBr3) perovskite nanocrystals to silicon nitride photonic cavities, enhancing room temperature light emission by an order of magnitude.
The full results from the second Phase 3 clinical study of LMTX confirm its efficacy as a monotherapy for mild to moderate Alzheimer's disease. The study showed significant slowing of brain atrophy and functional decline in patients treated with LMTX, while those receiving add-on therapy experienced no significant change.
Researchers have identified a neural mechanism that allows us to segment our experience into discrete memory units, which are then stored in long-term memory. This process involves the identification of boundary events, which trigger the reactivation of memories and enable the formation of prediction models.
Researchers discovered that humble leaders foster higher levels of creativity in teams when team members value open communication and collaboration. Humble leaders acknowledge their limitations, facilitate information sharing, and broaden the scope of team skills.
Researchers at Carnegie Mellon University developed a new method to improve chemotherapy nanodrug delivery by using an FDA-approved nutrition source. This approach reduces toxic side-effects and increases the amount of drugs reaching tumor cells.
A research team led by David Brankovits discovered that cave-adapted organisms can thrive on methane gas and bacteria near it, raising the possibility of similar life forms existing worldwide. The study found a complex food web involving tiny organisms and large shrimp.
An international team of researchers discovered a previously unrecognized genus of extinct horses in North America, diverging from the main trunk of the Equus family tree around 4-6 million years ago. The new species, Haringtonhippus francisci, was a widespread and successful species that survived until roughly 17,000 years ago.
The new printer can print objects up to 10 times faster than existing commercial counterparts due to its compact printhead design. The team used a screw mechanism and laser to speed up the printing process, enabling it to fabricate detailed objects in several minutes.
The Vega de Granada area in SE Spain sinks up to one centimeter per year during dry periods. This land subsidence is caused by the exploitation of the aquifer and is a concern for village residents.
Researchers at NIST develop a new approach to testing multilayered, three-dimensional computer chips using microwaves. This method provides real-time insight into material performance and defects, potentially reducing electromigration issues and improving chip stability.
Researchers identified several lncRNAs linked to ovarian cancer, including DNM30S, which correlates with worse survival rates. Targeting these lncRNAs may represent a viable treatment strategy for ovarian cancer.
Scientists at Boston Children's Hospital have identified the molecule responsible for releasing interleukin-1 (IL-1) from immune cells. The study found that gasdermin D enables IL-1 release without killing the cell, which could lead to more potent and long-lasting vaccines.
A study of 42,230 adults found that delaying surgery for hip fracture beyond 24 hours was linked to a small but significant increased risk of death. Patients who had surgery within 24 hours had a lower risk of complications such as heart attack and pneumonia compared to those who waited longer.
A new technique using machine learning can improve the diagnosis of melanoma by identifying the optimal amount of context around skin lesions. By segmenting images into two parts, separating the lesion from surrounding skin, researchers found that a limited border beyond the lesion enhances classification performance.
Researchers from Children's Hospital of Philadelphia highlighted racial disparities in bystander CPR methods and found that children with hypertrophic cardiomyopathy are at risk for sudden cardiac death. Targeted training may increase bystander CPR rates and improve outcomes.
Researchers at The Feinstein Institute discovered dozens of genetic variations linked to general cognitive ability. These findings have the potential to aid in targeted treatment for cognitive disorders, including Alzheimer's disease, schizophrenia, and attention deficit hyperactivity disorder.
A new study published in the Journal of the American Medical Association shows that Fecal Microbiota Transplant capsules are just as effective as colonoscopy in treating C. difficile infections. The capsule delivery method is non-invasive, less expensive, and has no risks associated with sedation.
Scientists at Bielefeld University and University of Münster are studying how animals adapt to their environment through individualised ecological niches. They explore the genetic and behavioral factors influencing these adaptations.
Researchers at the University of Bristol created a new platform for producing desperately needed antibiotics by combining synthetic biology with biology and chemistry. The team successfully generated a semi-synthetic pleuromutilin derivative with enhanced antibiotic activity, addressing the growing resistance to existing antibiotics.
A Sydney team has invented a microcircuit based on Nobel Prize research, miniaturizing a crucial component for quantum computing. This innovation could pave the way for large-scale integration of quantum circuits and manufacturing in massive quantities.
A James Cook University study found nearly three quarters of office workers believe there is a negative relationship between sitting down all day and their health. The study suggests that education on the benefits of standing and buy-in from management are crucial to implementing effective behavior change strategies.
A new study found that weight loss through diet and exercise significantly slows down the degeneration of knee cartilage in obese individuals. However, weight loss achieved solely through exercise had no significant impact on cartilage degeneration, suggesting that a balanced approach involving diet is crucial for protecting the knees.