A massive genetic analysis of over one million people has revealed 535 new genes linked to high blood pressure. The discovery sheds light on new biological pathways for blood pressure regulation and holds promise for improved cardiovascular disease prevention.
Scientists have developed a metal-organic framework that can take up gaseous ammonia at densities similar to those of liquid ammonia, making it suitable for storage and handling. The framework's unique sorption mode allows for reversible adsorption and desorption of ammonia.
A new study by North Carolina State University reveals that wineries with more sustainable practices experience better financial performance when they feel competitive pressure. Conversely, those without significant competitive pressure are more likely to adopt new sustainability measures.
A root extract of Fallopia multiflora has been shown to extend the lifetime of nematodes by almost 19% and protect them from oxidative stress. The primary component of the extract, similar in structure to resveratrol, activates sirtuins that control ageing.
A new long-acting injectable implant developed by UNC School of Medicine researchers has shown promising results in animal models, delivering anti-HIV medication over time with minimal toxicity. The implant can be quickly and safely removed if needed, making it a potential game-changer for HIV treatment and prevention.
Researchers at Duke University used a supercomputer to computationally predict the optical properties of layered hybrid organic-inorganic perovskites, opening new material design space for light-based devices. The study successfully matched experimental observations, proving the accuracy of computational models.
Researchers studied copper-based superionic crystal CuCrSe2, revealing copper ions flow like liquids above a certain temperature. This discovery could lead to the development of more efficient and safer rechargeable batteries by replacing liquid electrolytes with solid superionic materials.
Researchers from MIT, SMART, and NTU have discovered a new molecular pathway that could boost the body's Natural Killer cells to fight malaria infection. The treatment targets MDA5, a receptor used by NK cells to identify infected red blood cells.
Rice University researchers are working to develop cell implants that can sense blood glucose levels and produce insulin on demand for Type 1 diabetes patients. The project aims to eliminate the need for patients to monitor their blood glucose and administer insulin shots, potentially leading to a cure for this autoimmune disease.
A CU Boulder-led study found that targeted training can improve spatial reasoning skills in young adults, increasing their performance in geoscience classes. After one semester, 70% of trained students showed significant improvement in spatial skills, with many reporting enhanced abilities in other science classes.
Research published in Folia Phoniatrica et Logopaedica suggests that dummy use, breastfeeding, bottle use, and thumb sucking in early years do not cause or worsen phonological impairment, the most common type of speech disorder in children. The study found no significant association between sucking habits and speech delay.
Scientists have found that low TIP60 expression leads to uncontrolled jumping gene expression, triggering tissue inflammation that supports tumor growth. The discovery opens new avenues for cancer treatment using anti-HIV drugs.
A new study by Prof. Hyuncheol Bryant Kim and colleagues found that education can enhance an individual's economic decision-making quality. The research team conducted a randomized controlled trial in Malawi and found that those who received education support had higher scores of economic rationality.
A study of 6.5 million hectares of Brazilian Amazonia found that carbon losses from El Niño forest fires were three to four times greater than expected. The analysis showed that uncontrolled wildfires in understorey areas resulted in high immediate CO2 emissions.
A new analysis found that nonfatal injuries in the US cost over $1.8 trillion in 2013, with falls and being hit by objects causing most prevalent causes of injury. The study highlights preventable measures, such as well-designed safety devices and laws, to reduce deaths caused by injuries.
A pilot study found that pregnant women with a history of depression or bipolar disorder process infant facial and vocal signals of emotion differently. Pregnant women with bipolar disorder had difficulty recognizing all facial expressions, while those with previous depression showed a negative bias in adult facial expression recogniti...
Researchers found that a gene variant, 5-HTTLPR, reduces the risk of depression associated with friendship and relationships stresses when young, but increases the risk following financial stress. This discovery may offer new insights into the evolution of depression.
A clinical trial suggests that individuals with bipolar disorder who have a high-quality diet, low BMI, or anti-inflammatory properties may respond better to nutraceutical treatment. The study found statistically significant results but emphasizes the need for replication in larger trials before firm conclusions can be drawn.
A new study published by the Keck School of Medicine of USC found that an online care delivery model is equivalent to in-person care for improving psoriasis symptoms. Patients with chronic skin diseases need ongoing care, and depending on where they live, their access to dermatological care can be variable.
The nationwide Chinese survey found that childhood overweight/obesity prevalence increased to 16.8% and children underestimated their weight status at the start of the study by 49%. Children with a higher body image had lower increases in BMI over time.
A recent study found that species-rich subtropical forests can absorb up to twice as much carbon as monocultures, showcasing the importance of biodiversity in forest productivity. Reforestation with a variety of tree species is recommended to promote both ecological and economic benefits.
Researchers found antibiotic-resistant bacteria in sink traps of an Israeli hospital's intensive care unit. Implementing sink contamination prevention guidelines eliminated new infections and zeroed out infections altogether. The study highlights the importance of proper hygiene practices in preventing the spread of resistant bacteria.
Researchers at the University of Delaware will study clostridium bacteria for biofuel production, aiming to create sustainable energy from renewable resources. The project seeks to demonstrate that using multiple complementary microorganisms can improve process yields and create valuable chemicals.
The new guidelines update previous recommendations, prioritizing patient-centric care, medication adherence, and lifestyle management. They also highlight the importance of metabolic surgery, metformin as first-line therapy, and personalized medication selection based on patient preferences and comorbidities.
A study of top-ranked US hospitals reveals noncompliance with federal and state regulations regarding patient medical records request processes. Patients may face discrepancies in information provided, hindering their right to access protected health information under the Health Insurance Portability and Accountability Act (HIPAA).
Researchers at MUSC Hollings Cancer Center aim to find a less toxic, more effective treatment for metastatic breast cancer using a novel therapeutic antibody and innovative molecular imaging tools. The study will investigate the calcineurin/NFAT pathway's role in tumor growth and its potential inhibition by the antibody.
Researchers at Tokyo University of Agriculture and Technology have developed a simple technique to identify Small Cell Lung Cancer (SCLC) earlier using nanopore technology and DNA computing. The method recognizes specific microRNA patterns associated with SCLC, enabling early detection without invasive cell biopsies.
Researchers at the University of Toronto have discovered a way to select the outcome of chemical reactions by manipulating the 'impact parameter', a key factor in reaction dynamics. By directing reagent molecules towards targeted molecules with controlled accuracy, chemists can now control the products of chemical reactions.
A joint study by University of Sheffield and National University of Singapore found that combined impacts of deforestation and wildlife trade on Sundaland bird species are underestimated, with 50-90 species at risk of extinction by 2100.
The American College of Medical Genetics and Genomics has received a five-year, $13 million contract renewal to continue its work in newborn screening. The Newborn Screening Translational Research Network (NBSTRN) will support groundbreaking research and build upon its decade-long efforts.
Rice University scientists develop micron-sized spheres that trap and destroy bisphenol A (BPA), a synthetic chemical used in plastics. The spheres utilize reactive oxygen species (ROS) to degrade BPA into harmless chemicals, showing 90% efficacy after just one hour.
Research reveals that a single dose of cocaine can irreversibly alter brain circuits surrounding neurons associated with addiction. This discovery may lead to the development of medications targeting the extracellular matrix to reverse addiction.
A study by Yale researchers found that many top US hospitals fail to comply with federal regulations regarding patient access to medical records. Despite HIPAA guarantees, hospitals often make it difficult or expensive for patients to obtain their own records, violating state and federal guidelines.
Researchers at UTMB create DNA-based vaccine that cuts production costs and storage needs by up to 80%. The new platform has potential to serve as a universal platform for developing live-attenuated vaccines for many viral pathogens.
Tropical Storm Kong-Rey experienced extreme rainfall rates near its center, with rain falling at over 1.8 inches per hour in two areas northwest of the storm's center. The storm is weakening and expected to transition into the Sea of Japan, taking a turn toward the northeast.
Researchers found that turbidity currents in Monterey Canyon involve large-scale movements of the seafloor, contrary to previous conceptual models. The dense layer of water-saturated sediment moves rapidly over the bottom, remobilizing the upper few meters of the preexisting seafloor.
Researchers developed a cancer vaccine platform that can enhance oncolytic virus efficacy, activating human immune response against cancer cells. By using patient's own peptides, the treatment targets tumour cells, increasing T cell activity and improving therapy.
A new approach for managing chronic obstructive pulmonary disease (COPD) has been proposed, increasing physical activity levels by over 900 steps per day. The Urban Training intervention, developed by the Barcelona Institute for Global Health, combines tailored components to address individual social and cultural factors.
Researchers have designed a nanopore system capable of measuring different metabolites simultaneously in biological fluids, all in seconds. The system uses substrate-binding proteins as electrical transducers to detect single molecules, enabling real-time monitoring and diagnosis.
Researchers have characterized the electrochemical properties of polyaniline and polyaspartic acid thin films using NMR techniques. They found that PASP outpaces polyaniline in catalyzing hydroquinone and catechol oxidation, suggesting its potential as a catalyst.
Researchers have developed a novel strategy to measure material properties of the cell nucleus and its components using naturally occurring cellular dynamics. The study shows that human nucleoli behave like liquid droplets, which can influence disease progression, such as Alzheimer's and Parkinson's disease.
A new study published in the Journal of Nutrition Education and Behavior found that digital marketing of energy drinks was more persuasive with young adults than other marketing methods. The study showed that engagement with digital marketing increased energy drink usage among participants.
Cancer death disparities exist among US counties due to socioeconomic and behavioral traits, such as food insecurity, smoking, physical inactivity, and inadequate healthcare. Researchers identified these factors using a novel method, which may help public health experts target specific areas for reduction.
The study found that pro-inflammatory TNFα and anti-inflammatory CCL18 cytokines are increased in human atherosclerotic lesions, associated with cholesterol accumulation. The expression levels vary across plaque stages, with maximum levels in lipofibrous plaques.
Researchers at ASU have made significant advances in catalysis, a crucial energy technology. Their work, featured on the cover of the October edition of ACS Catalysis, explores electrocatalytic properties of binuclear Cu(II) fused porphyrins for hydrogen evolution.
The Global Alliance for Genomics and Health (GA4GH) has released three new interoperability standards: Beacon API, refget API, and Workflow Execution Service (WES) API. These standards address variant discovery, patient case discovery, reference sequence harmonization, and cloud computing to enable responsible genomic data sharing.
NASA tracks Tropical Storm Leslie's size and strength, forecasting heavy rainfall and strong winds. The storm is expected to bring significant wave activity to Atlantic Canada and New England coastlines.
A study by Columbia University's Mailman School of Public Health found that nearly one-third of Washington Heights residents experienced energy insecurity, leading to breathing problems, mental health issues, and poor sleep. Energy-insecure households were more likely to have children under 18 years of age and lower household income.
A study by Johns Hopkins Bloomberg School of Public Health found that US public and private health insurance policies are inconsistent in covering non-drug treatments for lower back pain. Most plans lacked clear coverage terms for acupuncture, psychological counseling, and physical therapy, with only a few covering these alternatives.
Researchers have used a novel fluorescence-based imaging technique to track shape changes in pore proteins that export molecules into the extracellular medium. The study provides insights into the mechanisms underlying protein function and could lead to new therapeutic opportunities for disorders such as cystic fibrosis.
A new study published in The Lancet Infectious Diseases found that a single dose of medication is not enough to eliminate trichomoniasis, a common curable STD causing serious birth complications and increasing HIV susceptibility. Researchers suggest multiple doses of treatment may be necessary for effective elimination of the parasite.
Scientists explore the property of electrons' spin to develop faster, smaller and more energy-efficient information technology. Researchers from Linköping University propose a device concept that can efficiently transfer electron spin to light at room temperature using gallium nitrogen arsenide nanopillars.
C3 regulates autophagy in beta cells, enabling protection from stress and potentially treating diseases like type 2 diabetes. Disruption of this mechanism can contribute to disease development.
A novel study suggests that people who participate in dementia prevention trials are primarily motivated by a desire to help others. The findings also highlight the importance of human interaction, with trial participants preferring staff-administered assessments over automated technologies.
A recent assessment of Alaska's carbon cycle reveals both alarming signs of rapid warming and potential counteracting effects. The state's forests, permafrost, lakes, and rivers store significant amounts of terrestrial carbon, which could be released into the atmosphere at an increased rate due to climate change. However, warmer temper...
Researchers found that brain activity patterns during sleep can reveal which memories are stored and which forgotten. The brain reactivates memory traces during certain sleep phases, especially when gamma band activity from deep processing is reactivated during ripples in the hippocampus, leading to later recall of images.
Researchers found that children of radar soldiers who were exposed to high doses of radiation had a higher rate of multisite de novo mutations and chromosomal alterations compared to offspring of non-radiation exposed parents. The results support the idea that accumulation of genotype damage by radiation can occur in the next generation.
A study found that a simple cleaning procedure using antibacterial shampoo and wipes can prevent therapy dogs from spreading MRSA to children with cancer. The decolonization process reduces MRSA carriage in both patients and dogs, improving patient safety.
A majority of U.S. beer drinkers are willing to pay $1.30 more per six-pack for beer produced with sustainable practices. The brewing industry can reap financial benefits from introducing energy-saving practices, according to a new study published in PLOS ONE.
A multi-institutional team has revealed new details about the HIV virus capsid structure and its role in the life cycle. Researchers found that a naturally occurring small molecule called IP6 plays an important part in both immature and mature phases of the HIV life cycle, making it a potential target for new treatments.