Researchers aim to develop a blood test to detect and track metastatic melanoma by analyzing circulating tumor DNA in the bloodstream, promising a more precise, individualized, sensitive, and quantifiable approach than current imaging tests.
Researchers have made significant progress in developing an acne vaccine by targeting a toxin secreted from Propionibacterium acnes bacteria. The vaccine has shown promise in reducing inflammation in human acne lesions. Future studies aim to engineer a non-toxic chemical or targeted vaccine formulation for its human application.
A new rapid imaging protocol has been developed and tested in Peru, quickly and cheaply diagnosing heart ailments in patients. The technique, which took 18 minutes and cost $150 per patient, revealed important changes in patient care and satisfied all imaging needs in 89% of patients.
Researchers found that religious people regularly assign significance to unremarkable events, leading to positive emotions like gratitude and contentment. The study suggests that giving meaning to everyday events is a general phenomenon across religious groups.
A study by Zicheng Yu of Lehigh University aims to understand the dynamics of peatlands in the Arctic Tundra and their role in mitigating climate change. The research will investigate the formation, distribution, and dynamics of peat patches in the Arctic Tundra and assess their implications for global carbon storage capacity.
This CVIA special issue brings together valuable new insights into research in cath lab procedures. Papers cover topics such as intravascular ultrasound-guided percutaneous coronary intervention, cardiac catheterization after cardiac arrest, and the current state of transradial access.
Fiordland penguins migrate 3,500-6,800 km in 69 days, traveling up to 80km/day, and arrive at two feeding grounds near Tasmania and Antarctica. Their behavior may be a remnant from an ancestral species, with successful breeders departing late to reach these distant areas.
Kristen DeAngelis will lead a new soil warming studies project with undergraduates annotating soil microbe genomes and investigating bacterial traits. The goal is to understand how bacteria thrive in warmer soils and their impact on the environment.
A recent expedition demonstrated how AI can dramatically accelerate exploration of deep sea ecosystems using autonomous robots and high-throughput data analysis. Scientists used unsupervised clustering to analyze seafloor images and identify biological hotspots, which were then surveyed and sampled within days.
A new study suggests that protecting key habitats outside of existing wildernesses and preserves is essential for conserving at-risk species with small ranges. The analysis shows that even half of the world's large wilderness areas may not be enough to protect many more species.
A large international collaboration identified 15 genetic variations linked to bone fracture risk, contradicting previous assumptions about clinical risk factors. The study highlights the importance of increasing bone strength in preventing fractures, rather than relying solely on calcium and vitamin D supplementation.
Researchers have made a breakthrough in treating childhood brain cancer by using stem cells to track down and deliver a drug to destroy medulloblastoma cells. The approach has shown promising results, shrinking tumors and extending life in laboratory models.
A new study reveals that six countries in the Americas - Brazil, the US, Mexico, Colombia, Venezuela, and Guatemala - accounted for over half of all firearm-related deaths in 2016. The study found that global firearm-related deaths exceeded conflict and terrorism deaths every year from 1990 to 2016, except for 1994.
Studies present new approaches to treating small coronary artery disease with drug-coated balloons, reducing the need for stents. Radial access is associated with lower rates of adverse events compared to femoral access in patients with acute coronary syndrome.
The National Science Foundation is investing in research to detect, disrupt and disable illicit supply networks that traffic people, weapons, drugs, human organs, and nuclear material. This funding supports a combination of engineering and computer, physical and social sciences to dismantle these networks.
Research found that migrating monarchs encounter high levels of disease when interacting with resident monarchs at tropical milkweed sites, which can lead to reproductive issues and reduced migration rates. Monarch populations are vulnerable to parasitic protozoan OE due to the loss of natural migration patterns.
Recent study reveals Amazonian precipitation in wet season has largely increased during the past three decades due to changes in sea surface temperature (SST) variability. This finding suggests a new perspective for studying long-term change in Amazonian precipitation.
Researchers have found that disrupting the non-canonical NF-κB pathway improves the effects of radiotherapy by enhancing the immune system's ability to interact with radiation. This new approach may lead to novel combination strategies for improving cancer treatment.
Researchers have discovered a key role for O-GlcNAc modifications in enhancing neuronal regeneration after injury. Altering sugar levels on proteins can alter metabolism, leading to improved regeneration outcomes.
A new catheter-based sclerotherapy technique is a safe and effective treatment for endometrial cysts, decreasing their size and relieving pain. The procedure also preserves ovarian function and improves future fertility outcomes.
A new study found that a change in breathing tube use can significantly improve survival rates for patients with sudden cardiac arrest. The new technique, which uses laryngeal tubes, resulted in higher survival rates compared to traditional endotracheal intubation.
Researchers at the Center for BrainHealth investigated concurrent cannabis and nicotine use on brain networks. The study found that combined use had greater connectivity compared to isolated use of either substance. These findings suggest unique contributions of cannabis and nicotine on brain network connectivity.
A recent study published in the European Heart Journal found that teenage smokers and heavy drinkers experience arterial damage, which can predict heart problems later in life. The research analyzed data from over 1,200 adolescents and showed that a combination of smoking and drinking significantly increased arterial stiffness.
Scientists found four pivotal strengthening events in the East Asian summer monsoon between 1250-1900 CE, with ocean sediments offering a more reliable record of past monsoon signals. The study provides insights into Asian monsoon dynamics and their impact on regional societies.
A crowdsourced intervention led to an 8.9% absolute increase in the number of gay men who got tested for HIV in eight Chinese cities. The campaign used a multimedia approach, including contests for images, concepts, and messages, to promote HIV testing.
A recent study found that girls who have closer relationships with their fathers tend to report less loneliness as they transition from first grade to fifth grade. This suggests that fathers can help their daughters feel more connected and reduce feelings of isolation.
A clinical trial of over 1,000 patients with implantable cardioverter defibrillators found that ranolazine was safe but did not significantly decrease the likelihood of the first occurrence of ventricular arrhythmia or death. However, it did lower the number of recurring episodes of ventricular tachycardia.
A new study uses modeling tools to identify areas where forest conservation in Fiji can reduce harm to coral reefs and their fish populations. The research found that protecting or restoring native forests can provide the most benefit to downstream coral reef systems.
A 40-year study found that vacations can prolong life by reducing stress. Men who took longer vacations had lower mortality rates than those with shorter vacation times, suggesting that stress reduction is key to cardiovascular health.
New research from Michigan State University challenges the traditional 'invisible hand' theory of market control. A third party's intervention disrupts trading relationships, establishing trust and loyalty among parties involved. This leads to favorable prices, but also creates a risk of runaway train-like effects unless regulated.
A recent study from Regenstrief Institute found that a patient's diagnosis is not the primary factor in determining whether a nursing home resident needs to be hospitalized. Instead, coordinated care systems and quality improvement opportunities are crucial in preventing unnecessary hospitalizations. The study highlighted gaps in commu...
The VERDICT trial found that postponing invasive examination and treatment for up to 72 hours is as good as a very early approach in patients with NSTE-ACS, particularly those with high risk. This contradicts ESC guidelines on immediate versus early invasive strategies.
A study found that a specific E. coli strain from retail poultry products is causing urinary tract infections in people, with nearly 80% of meat samples and 72% of patient cultures positive for the bacteria. The research suggests that cooking poultry thoroughly and handling it carefully are crucial to prevent foodborne illnesses.
A new study found that goats can differentiate between positive and negative human facial expressions and prefer to interact with the former. The researchers observed that goats spent more time approaching images of happy faces than angry ones, suggesting a preference for positive emotions.
Researchers found a 9% increase in HIV testing during the intervention period, with crowdsourcing effective in promoting HIV self-testing among MSM. The study suggests crowdsourcing as a tool for developing youth-friendly HIV services and improving treatment outcomes worldwide.
Researchers fabricated an asymmetric supercapacitor based on FeCo-selenide nanosheet arrays, demonstrating a specific capacitance of 978 F/g and cycle stability of 81.2%. The device also showed excellent electrochemical performance, providing evidence that FeCo-selenide could be the next-generation promising electrode material.
Treatment with irbesartan, a blood pressure medication, slows aortic dilatation in children and young adults with Marfan syndrome. The five-year study found a clinically important reduction in aortic dilatation rates, potentially delaying surgical intervention and reducing complications.
Researchers from Politecnico di Torino and NUST MISIS create a new metamaterial that cloaks nano-sensors, improving their accuracy in optics and biomedicine. The development is part of the Italian-Russian project ANASTASIA, funded by Compagnia di San Paolo.
A new technique called TSA-Seq measures distance of every gene from specific nuclear landmarks, building a 3D picture of the genome’s organization. Genes closer to nuclear speckles tend to be more active than those near the nuclear lamina.
New research at McGill University found that people with higher BMI tend to have reduced cognitive flexibility, increased volume in the left amygdala and decreased volume in certain memory structures. The study suggests a model where genetics play a role in obesity through brain anatomy and cognitive functions.
Researchers found that air temperature feedback, a process linking atmosphere and surface, amplifies surface warming in response to external forcing. This feedback kernel measures the ability of temperature feedback to amplify surface warming.
UTEP scientists have received a $6 million grant from the National Institutes of Health to develop new regimens and biomarkers for Chagas disease treatment. The researchers aim to improve the efficacy and safety of current treatments, which are toxic and have low effectiveness.
A large study found that low-carbohydrate diets were associated with a 32% higher risk of all-cause death over an average 6.4-year follow-up. Risks were also increased for coronary heart disease, stroke, and cancer.
Researchers analyzed data from over 5,700 pregnant women with heart disease and found that fewer deaths occurred during pregnancy compared to previous years. However, nearly one in ten women with pulmonary arterial hypertension died during pregnancy or early post-partum. Pre-pregnancy counseling is crucial to identify high-risk patients.
A recent study found that tree swallow females who absorbed a stress hormone through their skin had lower survival rates and smaller offspring. Another study showed that birds with stronger stress responses were more susceptible to lingering effects of stress.
A new study found that a parental training program improved toddlers' physiological regulation and sensitivity towards their children, which can lead to better emotional and social development. The study showed that the program reduced foster care placements and improved parents' behavior.
Research by an international team from the University of Vienna reveals that remote islands have higher numbers of non-native species, which can lead to extinction events and threaten unique island species. The study found that isolation from the mainland increases the number of non-native species, while native species decline.
A study published in the Journal of the American Geriatrics Society found that short-term decline in physical function was common among older adults treated with chemotherapy for breast cancer. However, about half of patients were resilient and able to recover their ability to function within 12 months.
A new model accurately predicts patterns of mosquito-borne Ross River virus epidemics, highlighting the importance of temperature in predicting disease transmission. The study suggests that warmer temperatures may increase transmission in some regions and decrease it in others due to climate change.
A UCLA-led study found that a combination of pembrolizumab and SD-101 can alter the tumor microenvironment, enabling the immune system to attack cancer more effectively. The treatment has shown promise in people receiving immunotherapy for the first time, with some patients experiencing complete tumor disappearance.
Researchers developed a three-factor model predicting burn patients at risk for acute respiratory distress syndrome (ARDS). The model includes inhalation injury extent, percentage of body burned, and von Willebrand factor levels. This prediction tool could guide clinical trials to prevent ARDS in high-risk patients.
Scientists developed an updated international approach to identifying a healthy diet by analyzing data from large global studies involving over 240,000 people from more than 50 countries. The new guidelines suggest higher amounts of fruit, vegetables, nuts, and fish in the diet to reduce cardiovascular disease risk.
A team of MIT researchers has found a way to balance the size of droplets used in spraying pesticides, making them stick to targets more effectively. The new method uses a fine mesh screen to break up larger drops into tiny ones, reducing waste and pollution.
Researchers designed a novel molecular wire with a polyyne backbone and a ruthenium-based unit, achieving higher conductance than previous organic molecular wires. The origin of high conductance lies in orbital splitting, which induces changes in the electron orbitals to facilitate electron transfer between metal electrodes and the wir...
A study of 200 Irish adults found that many struggle to understand food labels, particularly men and those at risk for cardiovascular disease. The survey revealed gaps in consumers' use and interpretation of nutritional information, highlighting the need for improved public education and enhanced labeling.
Research found cancer increases risk of death and rehospitalization in patients with broken heart syndrome. Patients with cancer also experienced higher risks of adverse events after discharge, highlighting the need for strict monitoring.
Researchers identified two essential genes involved in regulating REM sleep duration in mice. The knockout of these genes resulted in drastically decreased REM sleep and altered sleep patterns. This study provides insights into the molecular mechanisms underlying REM sleep, a crucial aspect of maintaining mental and physical health.
A team of researchers at the University of Minnesota has successfully 3D printed a hemispherical surface with an array of light receptors. This breakthrough discovery brings scientists closer to creating a 'bionic eye' that could potentially restore vision in blind individuals.
A new nanoactuator system has been developed that can tune the conformation of biomolecules using an electric field. The system uses a gold nanoparticle tethered on a conducting surface, which can be moved reversibly using electric fields and monitored optically via changes in its plasmon resonance.
Researchers have developed a new laser technique to bind aluminum with plastic in injection molding, creating stronger lightweight materials. The method uses continuous infrared lasers to pretreat aluminum sheets, improving adhesion strength and paving the way for more efficient vehicles.