Researchers found that reducing secondary mitral regurgitation in heart failure patients did not improve survival or symptoms, suggesting the procedure is futile. Despite successful procedure completion, there was no significant difference in primary endpoint outcomes between intervention and medical treatment groups.
Researchers studied blood samples from 3,740 children and 1,074 adults in Managua, Nicaragua, after the 2016 Zika epidemic. The study found a high post-epidemic seroprevalence of 36% in children and 56% in adults, with immunity rates higher in females and increasing nonlinearly with age.
A new study reveals that even deep coral reefs in Palau are exposed to thermal stress at intervals different than those near the surface. By combining sea level and temperature data sets, researchers developed a forecast tool for predicting temperature stress on corals up to 150 meters below the surface.
A study of over 40,000 patients found that myocardial injury, major bleeding, and sepsis contributed to nearly three-quarters of all deaths after noncardiac surgery. Most deaths were linked to cardiovascular causes, with cardiologists playing a crucial role in preventing further complications.
A study of over 1,000 motor vehicle accident survivors found a common genetic variant in the stress response gene FKBP5 linked to increased chronic pain. The researchers discovered that addressing this interaction between the genetic variant and post-traumatic stress may represent a supplemental or alternative treatment option.
Researchers have successfully created 3D human liver tissue from human stem cells and implanted it into mice with liver disease, demonstrating improved liver function. The study showcases a promising approach to developing human liver tissue implants that could reduce the need for animal testing.
A new study suggests that paternal diet influences offspring health by affecting sperm DNA methylation tags and seminal plasma immunological responses. Mice fed a low-protein diet had overweight offspring with dysfunctional metabolism, highlighting the importance of a healthy father's nutrition for child well-being.
A new analysis of the LEADER trial suggests liraglutide treatment reduces the risk of death from heart attack and nonfatal stroke in people with Type 2 diabetes, regardless of their cholesterol levels. The study found that liraglutide also lowers LDL-C levels, an important marker of developing heart disease.
Qrypt has licensed a novel cybersecurity technology from Oak Ridge National Laboratory to fortify encryption methods. The company will incorporate the quantum random number generator into its platform, using unique and unpredictable encryption keys to create virtually impenetrable communications.
By 24 months old, children demonstrate awareness that their behavior can be positively or negatively evaluated by others. The study found that even young toddlers are attuned to the judgments of others and adjust their behavior accordingly.
Scientists discover TREM-1 amplifies inflammation, leading to liver scarring and cirrhosis. Targeting this receptor may prevent fibrosis and cancer development.
Researchers found that only 8% of studies included some primary care patients, and none were conducted solely in primary care settings. Primary care physicians should be represented in advisory boards, considered for study grants, and primary care patients need to be included in trials of drugs used in primary care.
Endurance athletes show more left atrial fibrosis than non-athletes, with the condition linked to a higher risk of arrhythmias and atrial fibrillation. The study suggests that increased left atrial fibrosis may help explain the higher incidence of arrhythmias in endurance athletes.
Researchers found that fishing in the Phoenix Islands Protected Area doubled before its implementation, leading to excess fishing equivalent to what was prevented by the reserve for 1.5 years. This suggests that anticipating marine reserves can trigger overfishing, undermining conservation efforts.
The Vibrio cholerae bacterium has evolved skills to survive in aquatic environments by 'hitchhiking' on predatory amoebas and establishing a replication niche within their osmoregulatory organelle. This adaptation may have contributed to the emergence of V. cholerae as a major human pathogen.
A study published in the European Heart Journal reveals that microvascular dysfunction is a prevalent underlying disease mechanism in patients with heart failure and preserved ejection fraction. The research highlights the importance of identifying patients at risk and developing targeted therapies to improve outcomes.
A new study led by Harvard T.H. Chan School of Public Health warns that high CO2 levels could lead to widespread nutritional deficiencies, affecting 1.9% of the global population by 2050. The research estimates that 175 million people will become zinc deficient and 122 million will become protein deficient due to lower crop yields.
A study found that air pollution exposure was associated with decreased cognitive test scores, particularly in verbal abilities. Reducing fine particulate matter concentrations could lead to significant improvements in cognitive performance, equivalent to a shift from median to 63rd percentile scores.
The study provides guidance on synthesizing high-quality graphene with less domain boundaries. Researchers found that the lattice orientation of graphene is determined by the Cu crystal it is nucleated on, regardless of the substrate's crystallinity.
Researchers from Massachusetts General Hospital found that immune cells responding to a stroke or brain injury in an animal model are more likely to come from the skull's bone marrow. Microscopic channels were discovered in the skull's inner layer, allowing inflammatory cells to migrate directly to the brain surface.
Researchers at Yerkes National Primate Research Center have successfully reversed the effects of parental stress on offspring by exposing parents to behavioral interventions. The study found that this approach breaks the cycle of intergenerational stress, reducing sensitivity and structural imprints in offspring.
Researchers at Stanford University School of Medicine discovered that people with cardiomyopathy have abnormally short telomeres in their heart muscle cells. This finding opens the door to new research and drug discovery, potentially allowing for the identification of individuals at risk for heart failure due to genetic defects.
A large study found that care coordination strategies significantly reduce symptoms of depression and improve health in seniors with multiple chronic diseases. The review included 25 studies and 12,579 older adults, highlighting the potential benefits of managing co-existing chronic illnesses in a coordinated manner.
A recent survey found that about 4.5% of US adults use e-cigarettes, with higher rates among young adults and those in the LGBTQ community. E-cigarette use also varies by state, with estimates ranging from 3.1% in South Dakota to 7% in Oklahoma.
Researchers aim to address muscle power deficits in children with cerebral palsy, using a combined impairment and task-specific approach. The study will investigate the effects of PT3 on functional walking capacity, muscle performance, and architecture.
A study by University of California - San Diego found that 63% of breast milk samples from mothers using marijuana contained THC, the primary psychoactive component. The study suggests that while the amount of THC in breast milk is relatively low, more research is needed to understand its potential effects on nursing babies.
The COMMANDER HF trial found that rivaroxaban did not significantly reduce the risk of death, myocardial infarction, or stroke in patients with recent worsening of chronic heart failure and coronary artery disease. Rivaroxaban was associated with a lower rate of nonfatal stroke, but a higher risk of major bleeding compared to placebo.
Researchers used fMRI data to analyze brain activity of infrequent and frequent news readers, finding that the former group was better at predicting article popularity. The study suggests that people who don't normally read the news are more representative of general population trends.
A new UNLV study reveals that real estate prices for homes in wildfire-prone areas fall initially after a blaze, but rebound within one to two years. The phenomenon may pose a curse, as homebuyers prioritize environmental amenities over fire risk.
Health policy experts argue that expunging the program could worsen educational debt in America and threaten the medical workforce. The authors call for clarity and swift decisions to resolve the uncertainty, which is particularly unfair to recent graduates who are already facing significant loan debt.
Tafamidis improves survival and quality of life, reducing hospitalizations in patients with transthyretin amyloid cardiomyopathy. The therapy delays neurologic progression in a similar condition, and has been approved for this condition in the EU.
A new study led by Ohio State University found that algae poses a greater threat to freshwater fish vision than sediment, causing a 40% decrease in their ability to see in cloudy water. This could jeopardize the future of walleye and other fish populations if harmful algal blooms persist.
Researchers identified epigenetic changes that accompany glioblastoma progression and predict patient survival. DNA methylation sequencing can be used to predict clinically relevant tumor properties.
Tropical cyclone Lane was affected by strong westerly winds, causing a significant shift in its strongest storms east of the center. Despite this, the storm strengthened back into a tropical storm on August 27.
The article highlights the importance of providing care for transgender patients by incorporating patient-centered approaches and creating more inclusive healthcare environments. Key strategies include using preferred names, pronouns, and gender-affirming language, as well as training staff on trans-specific health issues.
A new study finds that toddlers are attuned to how others may be judging them and modify their behavior accordingly. Children between 14 and 24 months show inhibition when being watched with a neutral or negative expression, but press the buttons associated with positive responses more often.
Researchers found that ant colonies with as few as six individuals experienced significant benefits from group living, including better-surviving babies and faster growth. The study suggests that increases in group size alone can create benefits for small colonies, challenging the idea that strong groups require strong leaders.
Scientists from Tokyo Metropolitan University studied how microswimmers navigate gels with contrasting results based on swimmer features and size relative to the gel's mesh. They discovered two mechanisms for achieving motion, one through breaking time-reversal symmetry and the other by modulating arm amplitudes
Subordinate females in naked mole-rat colonies become more responsive to pup vocalizations after consuming queen's feces or estradiol, suggesting a unique mode of communication.
Researchers at Cedars-Sinai Medical Center have developed a simpler and more accurate method to estimate body fat percentage than the widely used BMI. The new relative fat mass index (RFM) formula uses only height and waist circumference measurements, providing a better measure of body fatness without requiring expensive equipment.
Researchers found that the Ross procedure reduced death from all causes by 46% compared to mechanical valve replacement, while also decreasing stroke and bleeding complications. However, patients undergoing the Ross procedure were more likely to require reoperation due to graft failure.
A phase three clinical trial has shown that tafamidis can reduce deaths by 30% and cardiovascular-related hospitalizations by 32%. The treatment also slows the decline in quality of life among patients with transthyretin amyloid cardiomyopathy. If approved, it would be the first medical therapy for this life-threatening disease.
Researchers designed video games to enhance heuristic judgment in emergency medicine physicians. The intervention improved accuracy in trauma triage decisions, with participants who used the games showing a 17-18 point lower under-triage rate compared to those receiving no intervention.
NASA's Terra satellite detected three areas of strong water vapor concentrations in Tropical Depression 25W, indicating potential for heavy rainfall and intensification.
Researchers discovered that beluga whales and narwhals undergo menopause, mirroring killer whales' behavior. This reproductive strategy may have evolved due to increased relatedness among family members and the need for older females to contribute to group survival through knowledge sharing.
MIT researchers create a new technique to alter membrane proteins, making them more accessible for structural studies. The QTY code allows for the substitution of hydrophobic amino acids with hydrophilic ones, enabling water-soluble proteins that can be analyzed using X-ray crystallography or NMR.
A study by McLean Hospital calls for a unified approach to preventing suicides and other self-injury deaths. Researchers found that the estimated mortality rate from self-injury surpassed diabetes, prompting experts to emphasize the need for more effective prevention strategies.
Female refugees are more likely to become naturalized US citizens than male counterparts, according to a recent study. The study found that higher levels of education and longer US residency also contribute to increased naturalization rates among refugees.
A study defines mechanisms behind focused-ultrasound-assisted treatment of brain tumors, improving drug delivery across the blood-brain barrier and into abnormal tumor tissues. The approach enhances permeability of endothelial cells lining tumor blood vessels, increasing cellular uptake of anti-cancer drugs.
Researchers discovered a protein called HIF helps heart cells survive after a heart attack, but its effect is blocked by fats accumulating within the heart muscle in people with diabetes. Repurposed drugs that activate HIF may help prevent lasting heart muscle damage and improve recovery in Type 2 diabetics.
Japanese researchers from Osaka University analyzed Hayabusa particles to determine the age of asteroid Itokawa, finding it formed 4.6 billion years ago and was destroyed 1.5 billion years later. The study used precise isotope analyses to clarify the chronology of the asteroid's evolution.
A study published in PLOS ONE found that restricting high-sucrose diet to active times reduced fat levels in rats. The research team limited the diet to nighttime, resulting in lower blood and liver fat compared to an unrestricted diet.
Studies with rodent models show reduced anxiety and improved brain function with early treatment using the histone deacetylase inhibitor LBH589. This approach may offer a new therapeutic strategy for Huntington disease.
A study by Boston University School of Medicine researchers suggests that HIV RNA expression inhibitors can diminish atypical inflammation and restore immune function in HIV-infected individuals on combination antiretroviral therapy (cART). Chronic viral infection leads to immune activation, causing non-AIDS complications such as cardi...
Researchers discovered tiny tunnels in the skull that connect bone marrow to the lining of the brain, enabling immune cells to quickly reach injured tissue. The study found that these channels play a crucial role in inflammation and may be important in various brain disorders.
Hydroxyl-terminated diamond surfaces created via water vapor annealing maintain atomically flat surfaces and remove two-dimensional hole gas layers, enabling high-temperature operation.
The University of Texas at San Antonio has developed the world's smallest medical robot, made up of nanocomposite particles that can be remotely controlled by an electromagnetic field. These robots have the potential to target cancerous cells for treatment and potentially treat Alzheimer's disease.
The discovery of the Bombali virus in Sierra Leone's bats marks a significant breakthrough for the PREDICT project, which aims to find viruses before they spillover into humans. The finding suggests that bats are likely hosts of ebolaviruses and underscores the importance of understanding their role in preventing Ebola outbreaks.
Researchers develop radiomic signature to predict efficacy of immunotherapy in patients with solid tumors. The algorithm analyzes CT scan images to extract biological information, providing a predictive score for treatment effectiveness.
Researchers developed a new method to measure degeneration of sensory neurons grown in a lab, improving the screening of experimental therapies for neurodegenerative diseases. The automated test uses software-assisted analysis to accurately assess nerve cell densities and shapes.
Researchers have proposed a new model for Jupiter's birth, revealing three distinct phases of growth. The first phase was characterized by rapid accretion of small pebbles and core building, followed by slower accretion of larger planetesimals that brought energy to the growing planet.
A new intelligent machine, Image-Activated Cell Sorting (IACS), sorts cells based on their spatial and morphological properties using an image-driven approach. The platform has been optimized for analyzing individual cells and holds promise for making machine-based discoveries in biological sciences.
Researchers found that vamorolone improved muscle repair and strength in experimental models of LGMD2B, while prednisolone worsened muscle weakness and degeneration. The study suggests modified steroids like vamorolone may be an option for some patients with the disease.
University at Buffalo scientists discovered that the chemical methylene blue, commonly found in textile mill wastewater, is good at tasks associated with energy storage. The compound can capture, store and release electrons, making it a viable material for liquid batteries.
Research found that biodiversity increases live tree carbon storage by up to 20 megagrams per hectare, but has a smaller impact on overall carbon storage. Climate and site topography have a more significant effect on forest carbon storage.
Researchers identified APOBEC enzymes as major contributors to the development of aggressive skin cancer in patients with Butterfly Syndrome. The discovery reveals a mechanism that instigates tissue damage-driven cancers and provides new therapeutic strategies.
A study by Duke University researchers shows that slow and steady animals actually have a faster average speed over their lifetimes than fast but erratic ones. The analysis also applies to modern aircraft design, where jet fighters are surprisingly slow when averaged over their service lifetime.
The new journal tracks China's dominance and rise, analyzing historical, cultural, social, economic, and political impact of initiatives like AIIB and BRI. Global experts provide unique insight on the transformative effects on global mindsets.
Deaths from drug overdose and suicide in the US have surpassed those from diabetes, with rates increasing by 80% between 2000 and 2016. Researchers urge national initiatives to tackle common factors behind 'self-injury', citing trauma, adversity, and mental health issues as key drivers.
A large-scale study found that reducing the frequency of blood transfusions in cardiac surgery patients results in similar or better patient outcomes, while also saving blood and reducing costs. The study involved over 5,200 patients across 19 countries and suggests a new approach to transfusion therapy.
Scientists have observed intersubband transitions in few-layer 2D materials using s-SNOM, revealing a new class of materials for infrared detection and emission. The study also shows potential for compact integration with Si CMOS.
Researchers reduced household lead levels and found significant reductions in dust lead levels, especially among black children. However, the intervention did not result in significant neurobehavioral improvements, such as improved IQ or behavior. The study suggests that eliminating residential lead exposure may be necessary to fully p...
Researchers discovered a brain-heart biomarker that can identify mice at risk of developing post-cerebral malaria epilepsy. This finding could translate to humans and improve therapeutic approaches for patients recovering from traumatic brain injury or stroke, which are estimated to develop epilepsy in up to 15 percent of survivors.
Researchers argue that sugar is not responsible for obesity and metabolic diseases, citing evidence from multiple domains. Experts also highlight the importance of physical activity in determining metabolic health. The debate raises questions about the role of sugar in modern diets and whether restrictive recommendations are effective.
A new study published in JAMA Neurology shows that the Affordable Care Act's Medicaid expansion has reduced the number of young stroke survivors who stop taking their medications due to cost. The study found that nearly 31% of all stroke survivors aged 45-64 were covered by Medicaid, up from 24% in 2011-2013.
A study found that nearly 20% of children use prescription medications, with 7.5% using multiple medications simultaneously. Adolescent girls are most vulnerable to harmful drug-drug interactions due to higher concurrent use of antidepressants and other psychotropic medications.
Scientists at Washington University in St. Louis have created an algorithm to reveal connections between cells over time, potentially impacting circadian rhythms. The approach, called ICON, shows the strength of these connections, which could lead to a better understanding of brain disorders such as epilepsy and Alzheimer's disease.
Researchers at Predictive Science Inc. developed a complex numerical model to simulate the corona, using data from NASA's Solar Dynamics Observatory. Their prediction bore a striking resemblance to the Aug. 21, 2017, corona, indicating advances in the new model and its ability to reflect key features such as helmet streamers.
Researchers discovered a previously unseen 'ecosystem' in advanced breast cancer, where primary tumors emit signals to halt secondary tumor growth. The study found that activating the immune response can freeze secondary cancers, offering new hope for living with advanced breast cancer.
Researchers studied pancreas duct formation in mice and found that the network resembles road networks, with stronger ducts expanding and weaker ones shrinking. This study may lead to better understanding and treatment of cystic fibrosis and other diseases involving abnormal duct formation.
Researchers discovered a predictive biomarker for epilepsy by analyzing the connection between heartbeat irregularities and abnormal brain activity in mice. They found that anomalous heart rate patterns slightly preceded abnormal brain waves, allowing them to predict which mice would develop seizures with 100% accuracy.
Researchers found that cold climate cycles coincided with the absence of Neanderthal tools and the rise of modern humans in Europe. The limited diet of Neanderthals, which relied on terrestrial meat sources, may have contributed to their decline during stadials.
The NIH study found that the EXP2 protein forms a channel in the vacuole membrane of Plasmodium falciparum, enabling the parasite to obtain essential nutrients. This discovery could lead to the development of new drugs targeting this nutrient transport mechanism.
A new predictive model by Cornell University researchers aims to reduce food waste and spoilage by making 'sell-by' dates on milk cartons more precise. The model shows that refrigerated milk at lower temperatures significantly reduces the presence of spore-forming bacteria, leading to improved shelf life.
Engineered E. coli strains have successfully produced extracellular free haem using a novel strategy, overcoming previous limitations in production efficiency and yield. The optimized metabolic pathway enables high titer production of haem, paving the way for its use as a bioavailable iron-supplying agent in medical applications.
A new minimally-invasive surgical technique has been developed to create dialysis access for patients with severe kidney disease. The WavelinQ endoAVF System allows vascular surgeons to create a connection between an artery and vein using magnets, reducing the risk of complications and surgeries.
Researchers synthesized a novel rod-like metal-organic framework (MOF-5) nanomaterial for efficient removal of uranium hexafluoride. The study found that MOF-5 exhibited high sorption capacity and was an effective candidate for U(VI) enrichment, alleviating environmental pollution pressure.
Researchers create standardized model by reclassifying bacteria into 121 separate genus groups across 29 different families. The study uses metagenomics and genome sequencing technology to overcome historical difficulties in classifying microbial species.
Researchers at UCSB and the University of Oregon discovered that efforts to close off fishing in marine reserves paradoxically led to more fishing, exacerbating habitat degradation. The preemptive behavior was equivalent to 1.5 years of avoided fishing following the ban.
A study published in Frontiers in Zoology found that traffic noise may contribute to aging in Zebra finches, with birds exposed after fledging having shorter telomeres. The researchers suggest that this period is critical for song learning and development, making birds more sensitive to noise.
Researchers discover a new type of human brain cell that has never been seen in mice and other laboratory animals. These 'rosehip neurons' may play a role in fine-level control between regions of the human brain, and their absence in rodents suggests difficulties in modeling human brain diseases.
A new study found that the Siberian Flood Basalts, a massive volcanic eruption around 250 million years ago, sent nearly 90% of life into extinction. The team discovered that chlorine, bromine, and iodine in the lithosphere were released into the atmosphere, destroying the ozone layer.
Researchers at Gladstone Institutes identify 156 genes affecting ATP levels in cells, shedding light on cellular energy production. The findings could lead to the development of new therapies for diseases such as mitochondrial disorders, heart disease, and neurodegenerative diseases.
Tropical cyclones regularly develop in the Eastern Pacific Ocean. NASA's GPM mission observed intense rainfall near Tropical Storm Miriam's center, with rain falling at over 190 mm per hour. The satellite's radar data revealed the 3D structure of precipitation within the storm, providing insights into energy release and fuel formation.
Researchers found that listening to yoga music before bed increased heart rate variability, while pop music decreased it. Additionally, yoga music reduced anxiety levels and improved participants' mood.
Researchers analyzed gomphotheres' tooth fossils for dietary patterns, finding evidence of tree browsing and herb grazing. The study suggests that the mammals' diets were flexible according to resource availability and latitudinal climate gradients.
A new study published in EClinicalMedicine found that the loss of treated bed nets between mass campaigns significantly increases malaria transmission. Continuous distribution approaches can help maintain access to effective nets.
Researchers have identified a gene variant linked to chronic pain after traumatic injury, specifically the FKBP5 gene, which regulates the stress response and is affected by microRNA miR-320a. Individuals with this variant are more likely to experience increased pain due to altered cortisol levels and nerve sensitization.
Researchers from Australia and the UK have isolated three related rust resistance genes that confer distinct recognition specificities to the stripe rust pathogen. This breakthrough could enable accurate monitoring and integration of these genes into breeding programs to combat evolving pathogens.
Dr. Lequerica's work focuses on the relationships between insomnia and fatigue after TBI, aiming to generate effective interventions to address the needs of TBI survivors. He has authored over 40 peer-reviewed publications and is a leading expert in brain injury rehabilitation.
The Affordable Care Act (ACA) has been associated with a decrease in cost-related nonadherence to medication among adult stroke survivors. This is primarily attributed to the increase in Medicaid coverage and subsequent reduction in uninsurance rates within this group.
Researchers have developed tools to break down pesticides in the environment using catalytic amyloids. The discovery shows that these molecules can facilitate multiple chemical transformations at once, offering a promising approach for OP detoxification. Catalytic amyloids have been shown to hydrolyze paraoxon by several thousand-fold.
Researchers observed 'antennal grabbing' behavior in three different cuckoo bee species in the genus Nomada, where males transfer pheromones during copulation. This phenomenon has been documented for the first time in this genus, shedding new light on the courtship and mating behaviors of these kleptoparasitic bees.
A team of Japanese scientists has demonstrated a method to produce novel light beams from synchrotron radiation, enabling the generation of X-ray vector beams. This breakthrough could pave the way for new applications in X-ray diffraction, scattering, and absorption/emission spectroscopy.
A new study published in PLOS ONE found that household food insecurity is strongly associated with increased mortality rates in adults. The study analyzed data from Ontario, Canada and found that more severe levels of food insecurity were linked to a higher risk of mortality.
A new study by NYU researchers found that people form impressions of others' personalities from facial features based on their pre-existing beliefs about personality. The study's findings suggest that face impressions are shaped by our own beliefs, and can be highly inaccurate but consequential in real-world outcomes.
Scientists have identified two rare fatty acids, Nebraskanic acid and Wuhanic acid, in the seeds of a flowering plant native to central China. The discovery could lead to improved performance of vegetable oils as lubricants and biofuels.
A new study explores the cognitive effects of childhood acute lymphoblastic leukemia (ALL) and its treatment on brain function. The research reveals that connectome disruption is associated with delayed neurodevelopment in long-term survivors, with younger age at diagnosis and longer chemotherapy duration linked to poorer outcomes.
Researchers found a 130% increase in fishing activity in the Phoenix Islands Protected Area before a full ban took effect, setting back conservation efforts. The study suggests that people will adapt rationally to policy changes, leading to unintended consequences for conservation goals.
A study published in the American Journal of Preventive Medicine found that nearly 1 in 3 US veterans who own firearms store at least one loaded gun unlocked. This practice contributes to heightened suicide risk among vulnerable individuals who perceive firearms as a means of protection.
Two new $1 million NSF grants will support RENCI's efforts to develop a high-performance platform for scientific data processing and detect unintentional data errors. The projects aim to improve scientific productivity, increase confidence in outcomes, and facilitate seamless integration of available resources and networks.
A new study among senior Singaporeans suggests that happiness is directly proportional with a reduction in mortality. Happy older people lived 15% longer on average compared to unhappy counterparts, with even small increments in happiness showing significant benefits for longevity.
Researchers found that inflammatory response triggered by primary breast cancer prevents tumor cells from growing in distant organs. Inhibitors of interleukin-1β, such as canakinumab, are being tested in clinical trials for potential benefits in preventing metastatic growth.
IUPUI researchers identified a unique compound in the seed oil of the February orchid, which could lead to the development of environmentally friendly lubricants. The discovery provides clues as to what makes the seed oil a superior lubricant, demonstrating better friction and wear reduction.
Patients with high blood pressure are at increased risk of developing dementia within five years, yet cognitive function is not routinely measured. A clock drawing test was found to be more effective in detecting cognitive impairment than the Mini-Mental State Examination (MMSE) in adults with high blood pressure.
Levels of some persistent organic pollutants (POPs) regulated by the Stockholm Convention are decreasing in the Arctic, according to an international team of researchers. The biggest decreases were in a byproduct of the pesticide lindane and PCBs, with mean annual declines of 9% and 4% per year across the Arctic region.
A new study reveals that active shooter training increases emergency department staff's ability to respond effectively in the event of an attack. 92% of participating nurses reported feeling better prepared after training.
A large trial found that long-term single antiplatelet therapy after stenting is relatively safe, but it does not reduce the risk of death or heart attacks compared to standard dual antiplatelet therapy. The study involved over 15,000 patients and followed them for two years.
Researchers used a quantitative method to analyze over 140,000 artworks and found a temporal evolution of artistic styles reflecting divisions in style during Renaissance, Modern, and Contemporary art. The study demonstrates the utility of quantitative metrics in assessing artistic style evolution.
Scientists at Scripps Research have developed a non-invasive urine test to detect the parasitic worm Onchocerca volvulus, causing river blindness. The new lateral flow assay uses a biomarker in human urine to identify active infections, offering a crucial tool for tracking outbreaks and treating current infections.
A new study from Binghamton University suggests that women's diets play a bigger role in their emotional wellbeing than men's. Women are less likely to experience mental distress until they follow a balanced diet and healthy lifestyle.
A $7 million grant will fund a 18-month study comparing two interventions: online CATCH-IT and in-person POD group therapy, to prevent depressive episodes among adolescents. The trial aims to identify which program has the greatest capacity for large-scale impact.
Rice University researchers have developed a fleet of autonomous aerial drones that can coordinate to detect and track airborne pollutants. The system, called ASTRO, will use real-time data to alert neighborhoods of hazardous conditions following extreme weather events.
A geographic profiling tool used to catch serial criminals could help reduce the casualties of human-tiger conflict. By analyzing data from 2,386 Sumatrans and 13 years of human-tiger encounter records, scientists identified three places with high risk and low tolerance for tigers.
Scientists develop FliptR, a fluorescent molecule that measures cell membrane tension, revealing how cells adapt their surface to volume changes. The discovery paves the way for applications in cancer cell detection and membrane tension regulation.
The Jiachala Formation, a key deposit in the Neo-Tethyan subduction zone, was formed in a submarine fan environment during Late Cretaceous (~88-84 Ma) at the active southern margin of the Asian plate. Provenance analysis indicates it originated from the Gangdese arc and central Lhasa terrane.
A global assessment by scientists reveals nearly one-third of world's farms use sustainable intensification practices, improving productivity and biodiversity. Less developed countries see the largest gains in productivity, while industrialized countries focus on minimizing harm to ecosystem services.
A team of neuroscientists at Columbia University has figured out how to tease apart the many roles EGFR plays in the body. They report their findings in PLOS Genetics, solving a long-standing question about EGFR signaling and development. The study sheds light on the link between EGFR and disease, offering clues for diseases like cancer.
Researchers used information theory techniques to track changes in rainfall, heat, soil moisture and carbon flow in two ecosystems before, during and after rainfall and drought events. The study found that stronger connectivity alters how rainfall affects moisture, heat and carbon flux in the system.
The European Commission has approved Kymriah, a personalized CAR T-cell gene immunotherapy, for treating pediatric and young adult patients with aggressive blood cancers. The therapy has shown strong and durable response rates, providing a new hope for young cancer patients in Europe.
The PoshBee EU Horizon 2020 project aims to support healthy bee populations and sustainable beekeeping practices in Europe. The project will integrate knowledge from academics, beekeepers, and farmers to quantify the exposure hazard of chemicals on bees and determine their impact on health.
Researchers identify PDGF pathway to improve anti-VEGF therapies for glioblastoma. Adding an additional inhibitor blocks PDGF, making tumors more sensitive to anti-VEGF treatments.