A new study reveals that sambaqui societies living in coastal Atlantic Forest areas between 8,000 and 1,000 years ago consumed a range of plants and had a more diversified economy than previously believed. Analysis of their middens shows evidence of plant cultivation and high consumption of carbohydrates.
A clinical trial led by CNIO's Luis Paz-Ares showed that immunotherapy significantly increases patient survival when administered alongside conventional chemotherapy. This opens the door to investigate its effectiveness in early stages of the disease.
A new research developed a platform to predict compounds with clinical potential for treating brain diseases. The platform uses machine learning and whole-brain activity imaging to identify drugs with higher therapeutic and clinical translation potential, accelerating the drug development process.
Acute flaccid myelitis is a rare but serious condition in children that can progress rapidly and result in persistent health deficits. The disease is usually caused by enteroviruses and requires urgent testing and medical attention.
Researchers developed a strategy to block GM-CSF protein, reducing toxicities and improving CAR-T cell efficacy. A second strategy involves combining CAR-T cell therapy with a drug targeting AXL protein, potentially enhancing potency and lowering toxicity.
A new study by Indiana University scientists found toxic flame retardants in newly manufactured children's car seats, posing risks to children's health. The researchers detected high levels of emerging flame retardant chemicals, including cyclic phosphonate esters and polybrominated diphenyl ethers.
A small survey of patients with diabetes found that 1 in 4 reported underusing insulin due to cost concerns. Poor glycemic control was a common result of this underuse. The study emphasizes the importance of making insulin more affordable.
Researchers at the University of Otago have discovered blocking oxytocin cells in the brain after a heart attack can improve survival outcomes. The breakthrough could lead to a new pharmacological drug targeting these cells, potentially improving cardiovascular patient outcomes.
A new decision tool accurately predicts short-term serious complications in COPD patients, decreasing unnecessary admissions and unsafe discharges.
Barts Charity has awarded £6.5 million to Queen Mary University of London to transform its Charterhouse Square campus, featuring new labs, offices, and biorepositories for world-leading research in medicine and dentistry. The funding will support the expansion of research capacity and enhance collaboration among teams.
Scientists have found magnetic evidence of oxygenation in a paleolake, suggesting that most water column and history contained oxygen. The study analyzed drill cores from the Nonesuch Formation, revealing a gradient of oxygenation according to water depth.
A joint US-African effort to test the Bharat Biotech typhoid conjugate vaccine (TCV) on 250 children aged 9-36 months in Burkina Faso. The study aims to evaluate the TCV's efficacy when co-administered with other routine vaccines, such as yellow fever and meningitis A vaccines.
A recent study by Clark University researchers reveals that tropical forests are under threat from massive infrastructure projects and resource extraction. The study highlights the urgent need for policy-making that protects forests and communities from corruption and human rights abuses.
Researchers studying gribble, a small marine crustacean, have discovered that their digestive system holds the key to converting wood into low-carbon fuel. Hemocyanins, proteins found in the crustaceans' blood, enable the breakdown of lignin, allowing for more efficient sugar release from wood.
Scientists have created a version of RNA that could have served as an early genetic polymer, with inosine replacing guanine to improve accuracy. The results suggest that inosine could have played a crucial role in the origins of life.
A new study found that nearly all hospital patients experience disturbances in at least one category during their stay, with a significant impact on outcomes. The researchers suggest that simple interventions can improve patient care and reduce readmissions.
Researchers have developed a new method to study the flu virus, allowing them to visualize individual proteins and understand how they contribute to the virus's success. The study suggests that variations in protein composition may be beneficial for the virus, enabling it to spread infection more effectively.
Scientists at USC and SLAC develop a 3D map of the structure of a cell receptor as it binds to misoprostol, a key drug for women's health. This research provides a starting point for new drug discoveries that could reduce maternal mortality rates.
A research group at Osaka University has observed magnetic reconnection driven by electron dynamics for the first time in a laboratory setting. The study uses high-power lasers to create plasma conditions similar to those found in space, allowing researchers to investigate electron-scale phenomena alongside macroscopic structures.
Retailers in minority and low-income communities are more likely to sell alternative tobacco products, such as cigars and e-cigarettes, due to consumer demand. These products have been found to be more accessible in predominantly White neighborhoods with higher retailer density.
Researchers have developed a tiny device that electrically stimulates the brain, paving the way for minimally invasive treatments for conditions such as epilepsy and Parkinson's disease. The Stentrode can deliver targeted stimulation without open-brain surgery, opening up new possibilities for treating neurological disorders.
A new study published in Circulation found that running a full marathon significantly raises concentrations of biomarkers indicating heart strain in amateur runners. The study suggests that shorter endurance races may reduce the strain on the heart muscle during competition.
A recent paper by Insilico Medicine introduces deep learning for aging research, revealing age as a key biological feature that can be predicted using various data types. The study also outlines the potential applications of this technology, including personalized immunotherapies and vaccinations.
Researchers discovered 40 new genetic variants associated with an increased risk of colon cancer, validating 55 previously identified variants. The study also identified a rare protective variant for sporadic colorectal cancer, offering hope for targeted treatments.
Researchers developed a noninvasive diagnostic imaging method for bladder cancer using machine learning analysis of nanoresolution images from urine samples. The method achieved 94% accuracy in diagnosing bladder cancer compared to cystoscopy, the clinical standard.
Researchers at Harvard University suggest that inosine could have served as a surrogate for guanosine in the early emergence of life. Inosine enabled RNA to replicate with high speed and few errors, supporting its potential role as a backbone of the first cells.
Quside co-founder and CEO Dr. Carlos Abellan has been recognized by the European edition of the MIT Technology Review's 35 Innovators Under 35 list for his work on quantum random number generators. The technology, which enables gigabit-per-second quantum random numbers, is crucial for ensuring long-term data protection in a hyper-conne...
A recent study found that despite a rise in telehealth participation, vulnerable populations continue to have limited access. Lack of accessible providers remains a major barrier for Medicaid beneficiaries, those with lower incomes, and rural communities. State policies alone may not be enough to increase adoption.
A study found that older adults with heart failure who take five or more medications are at higher risk for cognitive impairment and difficulty performing daily activities. The researchers suggest that healthcare providers should consider these limitations when prescribing medications, as they may unnecessarily expose patients to incre...
The LIGO and Virgo collaborations have detected 10 stellar-mass binary black hole mergers and one neutron star merger, with six of the black hole events previously reported. The new detections include GW170729, GW170809, GW170818, and GW170823, which are included in a new catalog of gravitational-wave events.
Vaccines have been proven to be safe and beneficial for society, but misconceptions persist. The World Health Organization requires vaccination checks during medical encounters, but many cases are missed. Digital tools like VaccApp and ViVI Score aim to improve vaccine communication.
Archaeologists used machine learning techniques to classify and predict the technological elements of ancient hunter-gatherer groups in Patagonia. The study identified two distinct 'landscapes' of technology, one for pedestrian groups and another for nautical societies, shedding light on their mobility patterns and interactions.
A study by UC Berkeley found that married couples who aged show more humor and tenderness towards each other, leading to lower rates of defensiveness and criticism. The researchers tracked the emotional interactions over a period of 13 years, revealing an increase in positive behaviors like affection and enthusiasm.
A meta-analysis of clinical trials found that home telemedicine programs for heart failure patients decrease mortality six months after hospitalization, but lose effectiveness after one year. The analysis also showed that these programs increase the odds of all-cause emergency room visits.
The Center for Central Nervous System Function at Brown University has been awarded a $12 million grant renewal from the National Institutes of Health's COBRE program. The funding will support five new research projects and develop new analysis tools to advance brain science.
A new UK study found that women experiencing domestic violence and abuse are more than twice as likely to request emergency contraception, highlighting a possible indicator of abuse. The research suggests that healthcare professionals can play a crucial role in identifying and referring these women to specialist support services.
A University of Central Florida study suggests that workplace abuse by managers may not lead to abusive behavior by lower-level leaders. In fact, prior victims of abuse are more likely to treat their own subordinates better after learning from their boss's bad behavior.
Scientists discover hundreds of unrecognized halogenated contaminants in polar bear serum, including polychlorinated biphenyls and perfluoroalkyl sulfonic acids. The study reveals increasing levels of these pollutants over the past two decades, posing potential health risks to the Arctic ecosystem.
Researchers from MIPT and Lomonosov Moscow State University developed an experimental setup combining thermal and X-ray analysis to study semicrystalline polymers. They found that a critical heating rate can prevent structural changes, revealing complex thermodynamic behavior behind the material's melting points.
Researchers at IST Austria found that plant cells inherit knowledge of where is up and down from their mother cell. The directional transport of hormone auxin sets up polarization, but this depends on polar distribution of PIN auxin transporters. Endocytosis and phosphorylation of PIN transporters are crucial for re-establishing polarity.
A study found that prenatal environmental factors, including maternal age and nutrition, influence genomic imprinting in humans. The researchers analyzed DNA methylation data from Gambian children and found varying levels of imprinting depending on the season of conception.
A new study published in Biogeosciences reveals that declining silicon concentrations in the European Arctic Ocean reduce diatom production, impacting the food chain and organic matter sinking to the seafloor. The research team confirms this effect in 95% of samples collected during a research expedition.
A study found that Indiana firefighters had a 30.4% death rate from malignant cancers, 20% higher than non-firefighters between 1985-2013. Heart disease was the second leading cause of firefighter deaths, with no difference in odds compared to non-firefighters.
A Stanford University School of Medicine study found that teens and young adults who receive their initial opioid prescriptions from dentists are at increased risk for opioid addiction in the following year. The study, which examined nearly 15,000 patients, found that those who received dental opioid prescriptions were more likely to c...
In a breakthrough study, researchers successfully delivered a microRNA called miR-126 via a nanocarrier to improve survival rates in a preclinical model of sepsis. The treatment resulted in over 67% of mice being alive at seven days compared to just 25% of untreated mice.
Scientists have created a lab-based method to monitor honey bee queen fertility, revealing the impact of worker nutrition on queen egg laying. The study found that worker bees fed with pollen paste resulted in slower egg laying rates for queens compared to those fed with bee bread.
A new scientific report highlights the importance of collaborative problem-solving skills for tackling modern problems. The research team identifies key cognitive and social components of CPS and emphasizes the need for evidence-based standards and curricula in education to develop these skills.
A new study by Ohio State University found that utility customers rely on perception of cost savings rather than actual savings when deciding to participate in energy-conservation programs. The study involved 8,702 customers and showed that consumers who thought they were saving more were more likely to renew their programs.
Researchers found that girls who gained weight rapidly between ages 5 and 15 were more likely to be obese at 24. A follow-up study of 182 participants found a 93% rate of overweight or obesity in those with accelerated weight gain, compared to 20-37% in other groups.
A study finds that resource extraction and infrastructure development lead to significant forest loss and marginalize indigenous communities. The authors suggest novel approaches balancing conservation and agroindustry goals through rigorous land use zoning and community-led resource management.
An international team has reported the induction of helimagnetism in a simple cubic crystal by carefully selecting ions of different size. Systematically replacing strontium ions with larger barium ions caused the lattice to expand until ferromagnetic order was disrupted, resulting in helimagnetism.
Tropical Cyclone Owen formed in the Southern Pacific Ocean and produced heavy downpours, with rain rates reaching over 53 mm/hour near its center. The GPM satellite captured powerful storms on the eastern side of the cyclone, dropping rain at a rate of over 94 mm/hour
Leading scientists propose eight steps to boost global soil organic carbon stocks, mitigate climate change and improve agricultural productivity. The KJWA aims to formalize these measures through coordination and financing.
Queen Mary University of London has received £6.5 million in funding from Barts Charity to develop a new teaching lab, Cell Culture Labs, Tissue Bank Lab, Mass Spec Lab, Microscopy Lab, and office spaces at its Charterhouse Square campus. The investment will enhance the school's capacity to host up to 100 new appointments over four years.
According to a national survey, 2.8% of US children have ever been diagnosed with autism spectrum disorder (ASD), while 2.5% currently have the condition. Despite treatment, 30% of children with ASD remain untreated.
Recent studies highlight the need for updated adaptation plans to address severe weather events, with hard-adaptive measures like seawalls increasing long-term vulnerability. Increasing hazard awareness through education can reduce vulnerability, while effective communication strategies can mitigate flood damages.
An international team of astronomers has confirmed over 100 exoplanets using a combination of space-based and ground-based telescopes. The discovery includes ultra-short orbital period planets and low-mass rocky exoplanets, offering insights into their formation processes.
Researchers reported promising early results from a clinical study of genetically engineered immune cells that recognize and fight cancer cells. The treatment generated excellent responses when used after chemotherapy, with 71% of patients achieving complete response.
Researchers at Dana-Farber Cancer Institute have made significant advances in understanding the progression of multiple myeloma from precursor conditions, suggesting potential new treatments. The study found that immune system cells in patients with precursor conditions undergo changes that affect disease progression, and a novel combi...
Research reveals that coffee compounds eicosanoyl-5-hydroxytryptamide and caffeine work together to maintain enzyme PP2A activity, dephosphorylating pathogenic α-synuclein proteins. This synergy prevents neurodegeneration and neuroinflammation in Parkinson's disease models.