Researchers at Helmholtz Munich have discovered a new cofactor, NUFIP2, that works with Roquin to regulate the immune response. This cooperative regulation helps limit immune responses to specific reactions and prevents inflammatory reactions.
The study provides the first atomic description of the herpes virus associated with Kaposi's sarcoma, allowing scientists to identify specific targets for antiviral therapies. This breakthrough could lead to the development of new treatments for both KSHV and Epstein-Barr viruses.
A collaboration between BTI Institute and the South East Texas Regional Planning Commission aims to identify current gaps in terrorist response plans and create a unified regional plan. The project will also provide templates and recommendations for nationwide use.
Studies show that home infusions can decrease infusion burden for selected patients and are cost-effective. Telemedicine may also improve outcomes but increases healthcare utilization. Urgent care access and patient education also lead to improved clinical outcomes and satisfaction.
A cross-disciplinary team developed a satellite, Micius, to facilitate secure quantum key distribution globally. The system has achieved significant milestones, including decoy-state QKD with kHz rates over 1200 km distances, demonstrating the potential for an ultra-long-distance global quantum network.
A new study published in the Journal of the American Geriatrics Society found that older hospitalized adults are less likely to have provider-ordered influenza testing than younger patients. The study included 1422 adults with symptoms of acute respiratory illness or non-localizing fever and found that only 28% were tested for influenza.
Researchers at University of Wisconsin-Madison have developed an economical and high-yielding way to produce furandicarboxylic acid (FDCA), a critical chemical for making renewable plastics.
A study published in The Journal of the National Cancer Institute found that patients with high intra-tumour heterogeneity of the oestrogen receptor are twice as likely to die from breast cancer over a span of 25 years. This risk holds true for Luminal A breast cancer subtype, which is generally considered to have a good prognosis.
Researchers at NIST have identified a toolset to study memristors, leading to deeper understanding of their operation and potential for more efficient devices. The team found that reducing the size of a memristor can minimize unwanted current pathways, suggesting ways to engineer better performance.
Dr. Mohammad Najafi is leading a $53,000 research project to examine the safety risks of steam sealing in repaired pipes, focusing on emissions and worker protection.
A model plant study reveals a previously unknown pathway for genetic material exchange in germ cells, crucial for understanding Fanconi anemia disease. The study identifies the key protein FANCD2's important function in meiotic crossover formation.
The patented AromaStick inhaler enhances pain management by changing pain dynamics and improving relief. In two field studies, participants experienced increased mood and well-being when using the inhaler.
A University of Córdoba research group has disproved a widespread assumption among geneticists regarding DNA structure. The study reveals that two types of gaps caused by spontaneous and deliberate breakage are not equivalent, contradicting previous understanding.
A national register study by the University of Turku and THL found that more adolescents are receiving psychiatric or neurodevelopmental diagnoses, especially girls, between ages 12 and 18. The diagnoses primarily relate to depression and anxiety, with limited psychotherapy treatment options available.
Researchers develop optimized titanium-mesh scaffolds that promote faster and more effective bone regeneration. The study found that softer implants enhanced healing, with results applicable to various types of bone defects.
A new smartphone app enables patients to remotely send images of their surgical wounds for earlier detection of surgical site infections and prevention of hospital readmissions. The study found seven wound complications detected, one false negative, and a high patient satisfaction rate.
Researchers at La Jolla Institute for Allergy and Immunology identified a hitherto unknown precursor for a poorly understood subgroup of killer T cells. Single-cell transcriptome analysis revealed an unprecedented level of heterogeneity among immune cells, upending the traditional view of immune cells as unvarying entities.
A team of researchers at the University of Cincinnati has discovered how myostatin, a signaling protein limiting muscle growth, is activated. This knowledge could lead to new treatments for diseases like muscular dystrophy, ALS, and cancer cachexia.
A new study by UTSA professor Chris Packham and colleagues reveals weaker-than-expected magnetic fields around a black hole, contradicting previous models. The findings shed light on the complex relationship between black holes and galaxies, hinting at a deeper understanding of these cosmic phenomena.
Researchers created the first network map for 200 plant sensing proteins, revealing unknown interactions and key proteins that act as master nodes. The map could lead to ways to increase plant resistance to pathogens, heat, drought, salinity, or cold shock.
Researchers found that city lights in metropolitan areas like Boston, New York, and Philadelphia attract large densities of migratory birds, even from far away. This can lead to increased mortality risks from collisions with buildings, vehicles, and predators like domestic cats, as well as resource depletion.
Research presented at the Crohn's & Colitis Congress provides guidance for physicians to enhance IBD patient care. Studies show that better management of anemia improves overall outcomes, while IBD patients need better understanding of CRC screening intervals.
Scientists at ICN2 have found that bone's mineral component exhibits flexoelectricity, which triggers the bone repair process. This effect is localized to the tip of microfractures and signals to osteoblasts where damage needs repair.
A new study published in The BMJ suggests that the duration of opioid treatment is a more potent predictor of abuse and overdose than dosage among patients with no history of recent or chronic opioid use. Longer treatment spells increase the risk of dependence, abuse, or overdose by up to 20% each additional week.
Researchers have made breakthroughs in IBD treatment with the approval of a new antibiotic and the use of Janus kinase inhibitors. These advancements aim to improve outcomes for patients who currently lack effective treatment options.
A recent study found that none of the 89 approved pediatric drug products include dosing information for obese kids. Obesity affects how the body takes up medicine, where it retains it and how quickly it is excreted. More efforts are needed to provide safe dosing guidelines for children with obesity.
Scientists from Tomsk Polytechnic University are developing a technology to burn weapons-grade plutonium in high-temperature gas-cool low-power reactors, converting it into power and thermal energy. The process also enables the desalination of water, making it suitable for areas without large water bodies.
Researchers have discovered a potential new therapy for eczema that also reduces asthma severity, offering hope for effective treatments for both conditions. The study found that alleviating skin inflammation can significantly reduce asthma symptoms.
A new algorithm developed by ETH Zurich and Stanford University aims to increase employment opportunities for refugees in Switzerland by up to 73%. By analyzing data on refugees' characteristics and labor market conditions, the algorithm provides a tailored recommendation for which canton each refugee is most likely to find work.
Researchers from Innsbruck and Vienna teams used artificial intelligence to design new quantum experiments, leveraging a projective simulation model and reinforcement learning. The AI-agent performed tens of thousands of experiments, discovering novel structures that could be tested in the lab.
A Kaiser Permanente study found that cognitive behavioral therapy (CBT) is a cost-effective treatment option for adolescents with depression who decline or stop using antidepressants. The CBT program was shown to reduce depression-related health care costs by $5,000 on average over a two-year period.
The Biophysical Society has announced its new and notable symposium speakers for the 62nd Annual Meeting. The session will feature cutting-edge research on ultrafast glutamate sensors, dynamic chromatin fibers, and more. The meeting will take place from February 17-21, 2018.
Women with MSH6 and PMS2 gene variants have a 2-fold or 3-fold increased risk of developing breast cancer. The study suggests more intensive screening for these women may be beneficial.
Researchers discovered that nuclei play a crucial role in cell movement, particularly in 3D environments. Cells lacking nuclei or disconnected from the cytoskeleton exhibit reduced mobility on soft surfaces and fail to move in three-dimensional matrices.
A team of scientists reports a Verwey-type charge ordering transition in Cs4O6, where molecular O2- entities form well-defined singly charged superoxide and doubly charged peroxide anions. The study sheds light on the mechanism of Verwey-type charge ordering phenomena in mixed-valence compounds.
Researchers found seven percent of Austrian hunting dogs tested positive for the disease, highlighting a potential new vector for tularaemia transmission. The study suggests that asymptomatic dogs may pose an additional risk of infection for people.
Researchers created a robot to aid in treating babies with oesophageal atresia, a rare genetic disease that affects the infant's oesophagus. The robot stimulates cells by gently pulling on tissue using sensors.
A comprehensive study has identified just a handful of bacterial taxa that dominate the Earth's soil globally. These abundant bacteria can be grouped based on five key environmental preferences, providing new insights into their roles in regulating nutrient cycles, plant productivity, and terrestrial carbon dynamics.
The KAUST team has developed a methodology for acquiring atomic-resolution images of beam-sensitive materials, such as metal organic frameworks, using transmission electron microscopy. This enables the precise alignment and determination of defocus values, reducing the procedure to a near-routine process.
Hawkeye's advanced eyesight can be used to explain the physiology of the human eye and its limitations. This can lead to discussions on genetic engineering, wearable technologies, and responsible innovation in genetics. The article suggests using Hawkeye as a tool for engaging students in scientific communication and outreach.
A new study published in PNAS shows that ocean currents can concentrate marine debris, known as flotsam, into small areas. This phenomenon has implications for ocean cleanup projects and could help predict where concentrations will occur.
Researchers identified two related genes, Nr2f2 and Nr2f5, that pattern the jaw by regulating stem cell generation of skeletal cells. This study offers clues for understanding craniofacial anomalies in humans, where equivalent gene mutations are present.
Native carnivores like leopards, bats, and vultures provide critical services such as disease regulation, agricultural productivity, and waste-disposal.
US Army Research Laboratory scientists improved chemical yield of diaminoglyoxime (DAG) synthesis by 80%, increasing material production per reaction. The new method reduces heat release, minimizing explosion and combustion hazards.
Archaeologists at Rice University have discovered glass production in sub-Saharan Africa, challenging previous theories about the origins of glass technology. The findings suggest that glass was widely traded across West Africa and had a significant impact on regional dynamics.
Researchers have discovered a way for plants to acquire phosphorus more efficiently by suppressing secondary root growth in favor of primary root growth. This trait allows plants to explore a greater volume of soil and acquire more phosphorus, making it beneficial for farmers growing in nutrient-poor soils.
Researchers at Gladstone Institutes have successfully created induced pluripotent stem cells using CRISPR technology, simplifying a key step in the process. This breakthrough offers new possibilities for treating currently incurable conditions and studying diseases.
Researchers developed CancerSEEK, a noninvasive blood test detecting cancer mutations and protein biomarkers in the blood. The test detected cancer with a sensitivity of 69-98% and was 99% specific.
A new study suggests that people who perceive their willpower as limited are more likely to feel exhausted and need breaks between mentally taxing activities. In contrast, those who view their willpower as limitless tend to feel energized and ready to tackle the next challenge.
Researchers have solved a biological mystery by detailing the step-by-step process of genome folding, which involves coiling up long chromosome tangles and twisting them into spiral staircase structures. The study provides an efficient packing strategy that explains how cells can reliably bundle their chromosomes during cell division.
Researchers used carbon isotopes to track shark feeding habits, finding that coastal sharks forage in a range of coastal food webs, while deeper ocean sharks rely on specific areas of colder water. The findings may help conservationists design more effective protection strategies for declining shark populations.
Research reveals that past work commitments can still affect employees negatively, hindering their ability to fully commit to new projects and supervisors. The study identifies common reasons for the end of these commitments, including changes in work circumstances and over-commitment.
A new mathematical tool, based on Bayes' Theorem, was developed to validate and improve methods for interpreting clinical genetic test results. The tool assessed the rigor of widely-used approaches and found that a system of 18 rules is statistically sound and objectively strong.
The Harrington Discovery Institute awards support groundbreaking research in cancer, diabetes, osteoporosis, and addiction. Physician-scientists receive financial backing and critical resources to advance their work from the clinical realm.
Researchers have found that post-fire logging operations are responsible for declines in spotted owl territory occupancy, contradicting previous reports of large forest fires. The study suggests that preserving natural processes and reducing human disturbance can help protect this imperiled species.
A study found that screening the general population for cancer genes is cost-effective, preventing more breast and ovarian cancers. This approach could lead to thousands fewer cases of these cancers, particularly among women over 30.
A comprehensive review of literature on coral resilience highlights the need for urgent action to reduce greenhouse gas emissions. The study also identifies novel management techniques and overlooked reef areas to protect against climate change impacts.
A new mouse study suggests that a high-salt diet can impair blood flow in the brain, leading to cognitive dysfunction. The researchers found that changes in the gut caused by a high-salt diet led to reduced blood flow and dementia-like symptoms in mice.
The new instrument uses OCT-based technology with an electrically tunable lens to produce higher quality images of the entire eye. This enables whole-eye imaging, improving patient experience and potentially reducing instrument costs.
A recent Portland State University study shows that the term middle class is too simplistic to describe economic status across different countries and cultures. The study found that increases in income did not necessarily translate to reduced structural inequality in Brazil.