The VTX-1 Liquid Biopsy System is a commercial, automated instrument that isolates clinically relevant CTC populations directly from whole blood. It achieves high recovery rates of spiked breast and lung cancer cell lines, with purities as low as <100 white blood cells per mL of processed blood.
The study reveals that the invasive Eurasian woodwasp outcompetes and kills native species due to its larger venom glands and earlier emergence. This threatens the fragile ecosystem in North American pine forests.
Researchers have demonstrated that cells navigate using molecular force from within, enabling them to turn and potentially leading to the development of new drugs. This discovery was made possible by the study of integrins, which are essential for cell interactions.
Researchers found PQQ can prevent fatty liver disease progression in young mice fed a high-fat diet by protecting their microbiome. The study suggests that maternal diet affects offspring's gut health, leading to an increased risk of developing the disease.
A nationally representative study found considerable variation in US nursing home hip fracture rates among facilities. The majority of the variation remained unexplained by measured characteristics, but psychotropic medication prescribing and staffing requirements emerged as plausible targets for initiatives to reduce hip fractures.
Researchers at Queen's University Belfast found that female cats exhibit a strong preference for using their right paw, while males show a preference for the left. This gender-based difference in limb use may help cat owners understand their pet's stress levels and behavior.
Researchers at TU Wien have developed a method to manufacture porous silicon carbide structures with controlled porosity, opening up new possibilities for sensor technology, optical components, and biological applications. The technique allows for the creation of micro- and nanostructures with unique properties.
A recent study found that latent HIV reservoirs exhibit inherent resistance to CD8+ T-cells, making it challenging to eliminate the virus. Researchers at George Washington University used their most powerful combinations against these cells, but were unable to kill the virus, which remained present at high levels.
Researchers at MIT have developed a new approach to rechargeable batteries using a metal-mesh membrane, which overcomes the limitations of previous ceramic membranes and enables cost-effective power storage for large-scale installations.
Researchers at MIT have designed an artificial synapse that can precisely control the strength of an electric current flowing across it, similar to the way ions flow between neurons. The team found that their chip and its synapses could recognize samples of handwriting with 95% accuracy.
A bioarchaeological study of cranial modification practices in the Colca Valley found a significant increase in prevalence over time, with oblique modification becoming predominant. This suggests that modification contributed to the creation of a new collective identity and reinforced social inequality.
A new 'long acting' medicine has been developed to prevent malaria using nanotechnology, providing therapeutic drug concentrations for months after a single dose. This innovation aims to remove the need for daily tablets and could provide an additional tool in combating malaria globally.
The Colorado Consortium for Prescription Drug Abuse Prevention at CU Anschutz Medical Campus receives a $1.5 million grant from the Colorado Health Foundation to advance its mission to reduce misuse and abuse of prescription drugs in Colorado.
The Northwestern University team developed highly efficient metadevices at millimeter-wave frequencies using inverse design principles and 3D printing. This approach starts with a function and asks what structure is needed to achieve the desired result, producing unexpected outcomes like broad bandwidth functionality.
Particle receiver CSP technology can nearly double molten salt temperatures, increasing efficiency and reducing costs. Researchers have tested a red sand approach that achieves high temperatures while minimizing energy loss.
A team of researchers from the Oak Ridge National Laboratory has discovered how microorganisms adapt to survive in phosphorus-poor environments. By analyzing genes and proteins, they found an increase in phosphorus-acquiring enzymes and a large number of genes that break down complex organic compounds like phytate.
A new study published in the American Educational Research Journal found that perceived gender bias is the most predictive attribute of whether a female chooses a college major. The study suggests that college administrators should examine the environments in different majors to increase female representation. Additionally, women are m...
A study has linked individual variation in biological motion perception to genetic factors, revealing a common genetic basis for heritable aspects of BM perception and autistic traits. Genetic influences account for up to 50% of individual variation in local kinematics processing, while environmental factors shape global configuration ...
A study by Florida Atlantic University researchers found that moisture conditions inside sea turtle nests significantly affect the development and sex ratios of turtle embryos. The coolest and wettest substrates produce 100% males, while warmer and drier ones produce fewer males.
Researchers found increased risk of congenital malformations with methimazole and propylthiouracil use during the first trimester. This association confirms the importance of minimizing MMI use in pregnancy and suggests reevaluating the current recommendation to switch from MMI to PTU.
Neuroscientists have created a detailed map of the connections in the subgenual cingulate area 25 (A25) of non-human primates. The research reveals strong links between A25 and brain areas involved in emotional regulation, stress response, and memory formation.
A new test developed by Stanford chemists combines the convenience of spitting in a cup with the reliability of blood tests to detect HIV infections earlier. The test was shown to correctly diagnose 22 people and demonstrate improved sensitivity compared to existing saliva tests.
Shallow lakes in agricultural landscapes will emit significantly greater amounts of methane due to the combination of warming and nutrient enrichment. Methane ebullition increases by up to 17-fold with high nutrient levels, highlighting the need for managing agricultural landscapes to minimize this potent greenhouse gas emission.
Research across 462 sites in the western US found that winter snow melt increased with rising winter temperature in humid areas, but not in arid Southwest regions. In these areas, spring snow melt occurred earlier as temperatures rose.
Cloud seeding with silver iodide resulted in the formation of ice crystals within 30 minutes, which grew up to 1 mm in diameter and eventually became precipitation as snow. The study provides valuable insights into the process of snow formation via cloud seeding, paving the way for further research.
Researchers at Idaho National Laboratory have developed a new fuel cell technology powered by solid carbon, which can utilize three times as much carbon as earlier designs. The innovation enables lower temperatures and higher power densities, making it potentially more efficient than conventional hydrogen fuel cells.
Research found discrepancies between satellite and global model estimates of land water storage in 186 river basins worldwide. GRACE satellites measured changes in water storage, which differed from simulations made by seven commonly used models. The study highlights the need for improved regional assessments to ensure accurate water a...
KAIST researchers designed metallic nanostructure substrates to enhance Quantum Dot LED efficiency and reduce production costs. The technology uses silver and aluminum nanoparticles to increase fluorescent properties of QDs, resulting in brighter displays and lower unit prices.
Studies examined point-light displays of biological motion in twins, revealing individual variation tied to genetic factors; participants with higher autistic traits showed impaired local BM processing. A shared genetic basis may underlie both perception and autistic characteristics.
A new study examines nutrient loss reduction strategies from three upper Midwestern states and finds promise in certain practices like cover crops and bioreactors. The researchers also assess the trackability and stackability of these practices, which will aid decision makers in choosing specific conservation practices to adopt or avoid.
Researchers at Berkeley Lab have developed a thermochromic material that works as both transparent and non-transparent, producing electricity when darkened. The material's reversible phase transition enables it to switch between these states without degrading its electronic properties.
A new analysis of marine fossils reveals that polar oceans warmed more than previously thought during the Eocene, a greenhouse period. The study's findings challenge modern climate models, which underestimated polar ocean warming by about 50 percent.
Researchers at The Scripps Research Institute identified the p53 gene as a master regulator of mesenchymal stem cells' ability to differentiate. The study found that a basal level of p53 is required for MSCs to act accurately in the body, and its deletion can lead to unexpected differentiation outcomes.
Wild Australian rice's unique genetics hold the key to improving drought tolerance, pest resistance, and nutritional benefits in commercial rice production. The study reveals that northern Australia's wild rices contain valuable genetic diversity closely related to domesticated rice, which can be cross-bred for improved crop resilience.
A new medical school elective at Boston University School of Medicine combines standard education with direct patient care experience to increase confidence and improve care outcomes for transgender patients. Students reported significant increases in comfort and knowledge after participating in the elective.
Researchers have discovered a way to minimize waste in solar energy capture by designing materials that can harness previously wasted light. This breakthrough could push solar cell efficiency beyond 30%, addressing limitations of silicon-based solar cells.
Researchers at Siberian Federal University have developed a new method for reducing nitrogen oxide emissions in heat power plants (HPPs). By modeling the process of coal burning and testing different fuels, they found that mechanically activated fuel can reduce Nox emissions by up to 50% compared to traditional coal. This technology ha...
Researchers at the University of California, Riverside, have created a new, highly efficient catalyst material that could significantly reduce the cost of producing fuel cells. The material, made from porous carbon nanofibers embedded with cobalt, outperforms industry-standard platinum-carbon systems but at a fraction of the cost.
Researchers have produced the first detailed images of a giant star outside our solar system, showcasing a nearly circular atmosphere with complex convection cells. The study confirms theories about the characteristics of these stars, providing insight into their future activity and appearance.
A study published in HortTechnology has found that bad posture can increase loads by 50% on the lower back and double on the shoulders, leaving people susceptible to chronic injuries. The researchers used 3D optical tracking equipment to analyze the movement of gardeners undertaking routine tasks.
Researchers discovered Asian elephants in Sri Lanka respond with alarm and retreat to bee sounds, similar to African counterparts. The study aims to develop effective community-based beehive fence deterrent systems to reduce human-elephant conflict and protect the endangered species.
Researchers compared global water storage trends from 2002-2014 using GRACE satellite data and seven hydrology models. The study found that model projections of climate and human-induced changes are likely underestimates.
Researchers found that human neurochemical profiles are consistent with enhanced sensitivity to social cues, promoting monogamy and reducing within-group aggression. Elevated serotonin and neuropeptide Y levels may have encouraged male provisioning, while a dopamine-dominated striatum could have led to increased brain size and language.
Researchers at Swansea University have discovered patterns in soil fractures that could speed up the decontamination of industrial brownfield sites. The technique uses fracturing to generate high-conductivity pathways for fluid exchange, reducing cleaning time and cost.
Researchers successfully produced a high-powered, randomly polarized laser beam using a 'Q switch' laser, which typically emits brief pulses of light. This breakthrough expands the potential applications of smaller and more powerful lasers in various fields.
Researchers at Brown University aim to store billions of terabytes of data in a single flask of liquid using synthetic molecules. The project, backed by a $4.1 million DARPA award, has the potential to enable computation through chemical reactions and improve information densities.
A new study by University of Waterloo researchers found that vaccines used by commercial fish farmers are not protecting fish from disease, with vaccinated fish showing more symptoms and higher death rates. The study highlights the need for veterinary pharmaceutical companies to redesign and test vaccines tailored to fish immune systems.
A computer-based language classifier predicted psychosis in at-risk youths with up to 83% accuracy, identifying disturbances in speech flow and tangential thinking as indicative of psychosis. The technology has the potential to improve prediction and prevention of psychosis by targeting cognitive deficits.
Researchers identified four fundamental building blocks for all proteins, which can be stacked together to form energy-rich molecules available to humans and other living organisms. The discovery could lead to applications in biomedical engineering, therapeutic proteins, and industrial catalysts.
Researchers at Lobachevsky University have developed a new type of magnetic semiconductor layer that demonstrates spin-dependent phenomena at room temperature. The layers, fabricated using pulsed laser deposition, exhibit ferromagnetic properties and unique spin-split band structures.
A team of scientists has identified the protein kinase MSK1 as a key regulator of dormant or latent metastases in estrogen-positive breast cancer. The study found that tumors expressing MSK1 have a longer period of latency with no symptoms, reducing the risk of earlier relapse.
Exposure to a widely used flame retardant chemical mixture can disrupt placental function, leading to altered production of the neurotransmitter serotonin. This study found evidence of endocrine, inflammatory and neurotransmitter signaling pathway disruption in placentas.
PTB physicists have developed a frequency-doubling unit that can endure transportation and maintain accuracy. The unit is based on a highly stable monolithic enhancement cavity for second harmonic generation, enabling reliable laser light for quantum-optical experiments.
Infants born in opioid withdrawal after utero exposure show a significant increase in torticollis and plagiocephaly. These abnormalities can be prevented with early preventive measures, such as occupational and physical therapy.
Researchers have used a material's persistent photoconductivity to stimulate PC12 neurotypic cells, demonstrating a faster and noninvasive way to influence cellular behavior. The technique, which was shown to increase calcium ion levels within the cells, has the potential to advance research on cellular behavior.
Researchers used global climate models to predict March US snowpack based on July 1 conditions, outperforming statistical predictions. This approach could improve water management and hazard preparedness.
Researchers at the University of Innsbruck used a sophisticated measurement method to create a chemical fingerprint of urban VOC emission sources. The study found that emissions from cosmetics, detergents, and food preparation contribute significantly to the total VOC burden, with some compounds leaving characteristic 'scent' in the air.
A new study found that one in three low-income renters face housing instability, linked to poor health outcomes and material hardships. Housing instability was associated with increased odds of adverse health outcomes, including poor caregiver health and food insecurity.
Researchers created a computer model using neural networks to predict areas prone to corruption, finding that longer government terms and certain economic variables increase the likelihood. The study aims to contribute to anti-corruption efforts by targeting high-risk regions.
A new study published in LGBT Health found that young men who have sex with men are less likely to receive school-based HIV education than their female-only sex partners. The study associated HIV education with reduced sexual risk behaviors, particularly among young MSM.