Researchers found a transient, shape-shifting mechanism in DNA that influences the frequency of spontaneous mutations, which can drive evolution and diseases like cancer. The study reveals that specific DNA sequences affect the rates of these errors.
Researchers used a novel lab-on-a-chip to study gene regulation in single E. coli bacteria under changing environmental conditions. The chip allows for the precise growth and behavior of individual bacteria to be tracked over several days, revealing new insights into bacterial adaptation strategies.
A new research from the University of Sydney suggests that athletes who delay specialising until later years may be more successful. The study found that younger swimmers were over-represented at lower age categories but relatively older swimmers excelled at higher levels.
An international team of researchers has confirmed that supermassive black holes in the centers of massive galaxies play a key role in regulating star formation. The study found that galaxies with more massive black holes form stars at a faster rate initially, but then experience slower star formation rates over time.
A comprehensive review of 30 years' worth of research concludes that lone star ticks do not transmit the bacteria that cause Lyme disease, but can transmit other human illnesses such as ehrlichiosis and red meat allergy. The evidence, based on over 60 published articles, shows that lone star tick saliva is a barrier against Lyme bacteria.
Researchers have developed a smart coating that mimics the structure of human skin, offering a balance between strength and self-healing capabilities. The coating, composed of polyvinyl alcohol and tannic acid, can heal itself like skin when cut and also kill bacteria.
Researchers from Kumamoto University developed a new electrodialytic ion transfer enrichment method to improve the sensitivity of analytical systems for various ionic solutes. This method enables fast and efficient detection in low-cost equipment, making it suitable for community health analysis in resource-limited areas.
The University of Texas at Arlington has received a $227,000 grant to develop the manufacturing process for the REHEAL glove, a bioengineered healing glove that delivers medicine to injured hands to speed up healing. The project aims to accelerate rehabilitation and improve patient care.
Research found that fertilized soils in the Central Valley contribute up to 40 percent of California's NOx emissions. The study suggests potential solutions through improved fertilizer management and soil conservation techniques.
Research suggests that the brain's insular cortex mediates approach and avoidance responses to others in distress. The hormone oxytocin plays a crucial role in regulating this process, influencing social affective behaviors.
Researchers at Naval Research Laboratory have discovered a new material that emits light much faster than conventional materials, enabling larger power, lower energy use, and faster switching for communication and sensors. The discovery could lead to 20 times more intense LEDs and lasers.
Researchers discover that low levels of microRNA miR-125a-5p correlate with high levels of protein TIMP-1 in human lung cancer cells. Increasing miR-125a-5p levels reduces cancer spread and increases cell death. TIMP-1's role is also explored, revealing its dual function in promoting or inhibiting tumor growth.
A study of European adolescents aged 12-17 found that only vigorous physical activity significantly reduced cardiovascular disease risk factors like BMI and waist size. Poor cardiovascular fitness was linked more closely to future heart problems than moderate activity.
Research found adults with psychotic disorders experience cognitive decline in early childhood and adolescence, suggesting potential for early intervention to prevent illness onset. The study tracked IQ scores and cognitive abilities throughout the first two decades of life among individuals who developed psychotic disorders in adulthood.
Research by University of Delaware oceanographer Wei-Jun Cai and colleagues reveals that coastal water is taking up a larger portion of atmospheric carbon dioxide. The study's findings, published in Nature Communications, may have important implications for understanding the global carbon budget and predicting greenhouse gas emissions.
A new special issue in PhytoKeys features 17 new species from Southeast Asia, showcasing the region's remarkable botanical diversity. The discoveries emphasize the urgent need for conservation and understanding biodiversity in the face of climate change and economic growth.
A University of Minnesota study found that multiple wetlands within a watershed can significantly reduce nitrate pollution in rivers and streams. The research highlights the importance of targeted wetland restoration as a strategy for improving water quality in agricultural regions.
A slab of sandstone at NASA's Goddard Space Flight Center contains over 70 preserved tracks of mammals and dinosaurs, including small theropods and pterosaurs, providing a rare glimpse of their interaction. The discovery sheds light on ancient times on Earth and offers insights into prehistoric life.
A study published in The BMJ reveals that chronic diseases, such as heart disease and diabetes, significantly increase cancer risk, accounting for over one-fifth of new cancer cases. Regular physical activity was found to reduce this risk by nearly 40%.
Research found that forest owners at greater risk of causing deforestation are more likely to participate in conservation programs when controlled harvesting is allowed. Sustainable timber harvesting was a key factor in their willingness to accept contracts, suggesting that such practices can enhance ecological impacts.
The Colorado potato beetle's genome provides insights into its ability to rapidly develop resistance to insecticides and spread to new climates. Researchers have discovered genes that enable the beetle to thrive on different plant hosts and tolerate toxins, but not new genes explaining rapid pesticide evolution.
A team of astrophysicists has created a map with 300 galaxies close to the Milky Way, classified based on stellar motion rather than morphological characteristics. The study reveals that circular orbits are common in lower mass galaxies, while 'hot orbits' are more frequent in higher mass galaxies.
Researchers used over 40 telescopes to observe a rare event: the blazar CTA 102 increased its brightness by 3,500 times. The team found that the jet's radiation and particles emit in multiple frequencies from different zones, creating a serpentine shape. This discovery supports theoretical models of jet instability and propagation.
A new web-based stress management program has been shown to significantly improve the quality of life and reduce distress in newly diagnosed cancer patients. The online program, developed by researchers from the University of Basel, provides patients with information, exercises, and strategies to manage their condition.
A new study found that pink sea urchin species are less vulnerable to climate change than other urchin species. The species is abundant at depths similar to spot prawn fishers and produces edible roe during winter. Legalizing fishing of pink sea urchin as bycatch could relieve pressure on vulnerable species.
A new study on turtle brain evolution reveals that their brains have changed slowly and constantly over 210 million years, with modern turtles showing a wide variety of brain shapes and sizes. The first turtles with fully formed shells were likely living on land, contradicting previous hypotheses about their origins.
The AR Girls project aims to promote science and computer science interest among young women through augmented reality design experiences. The team will work with local art organizations to create AR stories or games that address science questions and issues relevant to their communities.
A global clinical trial of CAR T-cell therapy tisagenlecleucel found that 61% of children and young adults achieved complete remission after treatment, with durable responses lasting months or years. Most side effects were short-lived and reversible, with overall survival rates exceeding 90% at six months.
Researchers prove the security of device-independent quantum cryptography using a new approach called entropy accumulation. This breakthrough paves the way for practical realization of such schemes with state-of-the-art quantum technology.
Researchers found that complex PTSD was most often present in people who had experienced childhood sexual abuse, while classic PTSD was more common among those who had serious accidents or witnessed traumatic events. Further research is needed to develop effective therapies for complex psychological trauma.
A University of B.C. study found Indigenous people suffered transportation-related injuries at a rate 1.89 times higher than the province's total population between 1991 and 2010. The injury rate for those living on reserves was significantly higher, while those off-reserves had a lower risk.
A new enzyme-linked immunosorbent assay (ELISA) for bioanalysis of bevacizumab has been developed with a high sensitivity and selectivity. The assay limits detection to 1.01 ng/mL and offers an effective working dynamic range of 3.07-100 ng/mL.
Research found that early access to palliative care significantly improves end-of-life quality indicators for patients with advanced cancer. Patients who received palliative care were more likely to die in a hospice or at home, rather than a hospital, and had better access to pain relief drugs.
New observations of Tabby's Star by the Canary Island Observatories suggest that interstellar dust is causing the star's unusual brightness fluctuations, rather than an alien megastructure. The data, published in two articles, show that different colors in the star's light are being attenuated at varying rates.
Researchers studying a new species of parasitoid wasp discovered it has a unique saw-like spine structure that allows it to break free from its host. The wasp, Dendrocerus scutellaris, is likely an endoparasitoid, feeding on live insects.
Researchers investigated ultraconserved elements and found that deleting individual enhancers does not cause major defects, but some subtle brain abnormalities persist. A second study on limb enhancers showed functional redundancy, highlighting the importance of these regulatory elements.
Scientists use super-resolution microscopy to reveal the fine detail of red blood cells' cellular mesh underlying the cell membrane. They discover that the mesh is a triangular structure composed of proteins, allowing for flexibility and elasticity in squeezing through narrow capillaries.
A study published in the American Academy of Neurology found that balance and eye movement exercises can help people with multiple sclerosis (MS) improve their balance and reduce fatigue. The exercise program showed significant improvements in balance, fatigue, and dizziness scores compared to a control group.
A new study from Washington University School of Medicine found that West Nile and Powassan viruses can cause brain damage and fetal death in mice, similar to Zika. The study suggests that these flaviviruses may also pose a risk to developing fetuses in humans.
A new study published in the European Journal of Preventive Cardiology found that standing burns more calories than sitting. By substituting standing for sitting for six hours a day, adults can expend an extra 54 calories, equivalent to 5.5 pounds in one year.
NASA's GPM satellite measured Tropical Cyclone Cebile's rainfall intensity at over 228 mm/h on January 31, 2018. The storm's eye featured a clear circular structure with deep convective banding and sharp eyewall.
A global, multicenter study has found CAR T-cell therapy to be safe and effective in treating patients with relapsed or refractory B-cell ALL. The therapy achieved an overall remission rate of 81% within 3 months of treatment, with a median length of remission lasting up to 20 months.
The University of Washington and Pacific Northwest National Laboratory are joining forces to research and develop new materials that will significantly influence tomorrow's world. The joint endeavor, NW IMPACT, aims to tackle areas such as materials for energy conversion, quantum materials, water separation, and biomimetic materials.
Researchers are exploring non-invasive biomarker tests to monitor organ transplant patients and prevent rejection. Current biomarkers fall short, but various teams are hunting for new markers such as RNA levels, exosomes, and proteoforms.
Researchers at NYU School of Medicine developed a community-based health program that achieved significant control of Type 2 diabetes in a high-risk population. After six months, over 55% of participants in the intervention group had blood sugar levels under seven percent.
The NASA Goddard Space Flight Center has confirmed that a satellite re-discovered on Jan. 20, 2018, is the Imager for Magnetopause-to-Aurora Global Exploration (IMAGE) satellite. The satellite was launched in 2000 and had been declared mission-ended after repeated failures.
Researchers at Rutgers University have created a 4D-printed shape-shifting smart gel that can morph over time and temperatures change. The gel can provide structural rigidity in organs like the lungs and create new applications in soft robotics, biomedical devices, and scaffolds for cell growth.
A new universe simulation model, IllustrisTNG, provides fresh insights into how black holes influence dark matter distribution, heavy element production, and magnetic field origins. The simulation reveals a high degree of realism in predicting galaxy clustering patterns and the influence of supermassive black holes on the cosmos.
Recent papers by Keck Graduate Institute professors James Sterling and Shenda Baker describe the interaction between ions and glycans on mucosal surfaces. The research highlights how different ion types affect the structure, electrical potential, and fluid behavior of airway-surface layers in the lung.
Researchers have created a stealth virus that effectively recognizes and infects tumor cells using adapter molecules. The virus is protected by a novel protein shield that prevents immune system elimination, opening up avenues for treating aggressive cancers.
Scientists at ICIQ discover a novel methodology to create carbynes using visible light and photocatalysts. They use these molecules to add chiral fragments to existing compounds, accelerating the drug discovery process.
Researchers at OIST have discovered a simple solution to the mystery of transitional flow, a phenomenon that has puzzled engineers for over 130 years. By analyzing individual patches of smooth and chaotic flow, they found that the law of resistance can be applied using Reynolds's original laws.
The blood test measures a specific peptide to inform scientists of Alzheimer's disease presence with 90% accuracy. It has the potential to accelerate therapeutic strategies development by speeding up patient selection for new drug trials.
A study published in Science Advances found that prenatal famine exposure leads to changes in DNA methylation, which can influence adult body mass index and triglycerides levels. The researchers discovered that these epigenetic changes are similar to those seen in the general population.
A Yale-led survey found that long-term research is crucial for advancing knowledge, particularly in addressing global change impacts. Scientists prioritize multi-site, observational, and experimental approaches over short-term experiments.
A comparative study of 1,227 individuals from three groups and seven cultures found that perceived threats to culture, traditions, and values predict outgroup hostility and violence. The research suggests that a 'Clash of Cultures' mentality underlies some Muslim-Western conflicts.
New research reveals hydropower dams significantly disturb river connectivity in the Andes Amazon, impacting migratory fish patterns and sediment flow. The study suggests that 100% of sediment will be trapped in downstream dams, altering natural river flow and regional cultural processes.
Research suggests that migraine is associated with an increased risk of cardiovascular diseases in both men and women. The study found a positive association between migraine and heart attack, stroke, blood clots, and irregular heart rate, particularly among women.
Researchers recorded laboratory-quality brain activity measurements outdoors using portable equipment, revealing differences in brain processing stimuli compared to indoor conditions. The findings suggest the brain may be compensating for environmental distractions, which could inform the creation of safer public spaces.
Researchers trained neural networks on thousands of images from simulated high-energy particle collisions to identify key features. The networks achieved up to a 95% success rate in this analysis. Machine learning algorithms will next be applied to actual experimental data to further advance our understanding of the universe's mysteries.